Immunopathologia Persa最新文献_第2页

Thymoma; clinical presentations, pathology, and prognostic factors – a surgery point of view 胸腺；临床表现、病理学和预后因素&外科学的观点

IF 0.8

Immunopathologia Persa Pub Date : 2023-08-22 DOI: 10.34172/ipp.2023.40581

H. Hemmati, M. Memarian

引用次数: 0

Comparing the effect of local injection of combined morphine, triamcinolone and lidocaine and lidocaine injection on pain intensity after mastoidectomy-tympanoplasty; a triple-blind clinical trial 比较局部注射吗啡、曲安奈德、利多卡因与利多卡因注射对乳突切除-鼓室成形术后疼痛强度的影响;一项三盲临床试验

IF 0.8

Immunopathologia Persa Pub Date : 2023-08-11 DOI: 10.34172/ipp.2023.39525

R. Talakoub, Gholamreza Khalili, Hoda Sadat Rohani

{"title":"Comparing the effect of local injection of combined morphine, triamcinolone and lidocaine and lidocaine injection on pain intensity after mastoidectomy-tympanoplasty; a triple-blind clinical trial","authors":"R. Talakoub, Gholamreza Khalili, Hoda Sadat Rohani","doi":"10.34172/ipp.2023.39525","DOIUrl":"https://doi.org/10.34172/ipp.2023.39525","url":null,"abstract":"Introduction: Postoperative pain control is one of the patient’s rights and the challenges of surgeons and anesthesiologists since about 20% of patients experience severe pain in the first 24 hours after surgery. Mastoidectomy and tympanoplasty are common surgeries in the head and neck area, in which profound and long-term analgesia is essential. Objectives: The present study investigated the effect of the combination of topical morphine, triamcinolone, and lidocaine compared to the control group. Patients and Methods: In the current clinical trial, 68 patients’ candidates for mastoidectomy-tympanoplasty surgery were included and randomly divided into intervention and control groups. The variables of demographic, pain, hemodynamics, extubation time, and received opioids were measured. Results: The results of the current study indicated a significant reduction in the patient’s pain scores in both groups (P=0.001), while the patients of group 1 had significantly lower pain scores than group 2 after 8, 12, and 24 hours in the ward (P<0.05). Moreover, a significant reduction was observed in systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean arterial pressure (MAP) in all patients during surgery (P<0.001). However, in patients who received morphine, triamcinolone, and lidocaine (group 1), SBP and MAP were significantly lower than group 2 after 40, 80, 100, 120, 140, and 160 minutes during surgery (P<0.05). Conclusion: The present study indicated that the combination of morphine, triamcinolone, and lidocaine compared to the control group could lead to better pain control, further reduction of SBP and MAP, reduction of post-operative opioid use, and delay during the first opioid administration. Trial Registration: The trial protocol was approved by the Iranian Registry of Clinical Trials (identifier: IRCT20200825048515N39; https://irct.ir/trial/57931, ethical code; IR.MUI.MED.REC.1400.064).","PeriodicalId":13454,"journal":{"name":"Immunopathologia Persa","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43404941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of agreement coefficient between chest computed tomography and echocardiography in the diagnosis of pulmonary artery hypertension in patients with systemic sclerosis; a pilot study 胸部ct与超声心动图诊断系统性硬化症肺动脉高压的一致系数评价一项初步研究

IF 0.8

Immunopathologia Persa Pub Date : 2023-07-30 DOI: 10.34172/ipp.2023.34435

A. Ahmadzadeh, M. Sheibani, F. Farsad, P. Dehghan, L. Gachkar, Samad Nazarpoor

{"title":"Evaluation of agreement coefficient between chest computed tomography and echocardiography in the diagnosis of pulmonary artery hypertension in patients with systemic sclerosis; a pilot study","authors":"A. Ahmadzadeh, M. Sheibani, F. Farsad, P. Dehghan, L. Gachkar, Samad Nazarpoor","doi":"10.34172/ipp.2023.34435","DOIUrl":"https://doi.org/10.34172/ipp.2023.34435","url":null,"abstract":"Introduction: Systemic sclerosis (SSc) is an autoimmune disorder that often presents with skin involvement. SSc affects various organs, and one of the most important of these organs is the cardiovascular system, which is one of the complications of this syndrome, including pulmonary arterial hypertension (PAH). Early diagnosis of this complication is very important due to the importance of the effect of PAH on mortality and morbidity of patients. For diagnosis of PAH, two methods of computed tomography (CT) scan and echocardiography are conducted. Objectives: In this study, we aimed to evaluate the agreement coefficient of chest CT scan in comparison with echocardiography in the diagnosis of PAH in patients with SSc. Patients and Methods: In a diagnostic study, which was conducted in Loghman hospital (Tehran-Iran), patients with a diagnosis of SSc were evaluated for pulmonary artery pressure (PAP) by echocardiography. For patients, a CT scan of the lungs was conducted and PAP was assessed. The results that obtained from the lungs CT scan were compared with the echocardiography results. Results: Fifty patients with SSc were evaluated. Eighty-four percent of patients were female and the mean age of all patients was 48.94 ± 11.02 years. About 16% of all patients had high PAP based on echocardiography and 28% of patients based on CT scan. Kappa’s agreement coefficient was 0.428 and Spearman’s correlation coefficient was 0.457. In other words, chest CT scan has a partly agreement with the echocardiography method (P value = 0.001). Conclusion: Chest CT scan has a high sensitivity, specificity, and accuracy compared to echocardiography as a screening method.","PeriodicalId":13454,"journal":{"name":"Immunopathologia Persa","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69814716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The comparative survey of phenotypic methods and the 16S rRNA gene sequencing method for detecting genus and species of non-fermented gram-negative bacteria isolated from blood samples in Isfahan, Iran 伊朗伊斯法罕地区血样中非发酵革兰氏阴性菌属和种检测的表型方法和16S rRNA基因测序方法的比较研究

IF 0.8

Immunopathologia Persa Pub Date : 2023-07-29 DOI: 10.34172/ipp.2023.39481

Shahnaz Eskandari, Nasim Shabani, A. Baradaran, S. Mobasherizadeh, S. Rostami, M. Derakhshan

{"title":"The comparative survey of phenotypic methods and the 16S rRNA gene sequencing method for detecting genus and species of non-fermented gram-negative bacteria isolated from blood samples in Isfahan, Iran","authors":"Shahnaz Eskandari, Nasim Shabani, A. Baradaran, S. Mobasherizadeh, S. Rostami, M. Derakhshan","doi":"10.34172/ipp.2023.39481","DOIUrl":"https://doi.org/10.34172/ipp.2023.39481","url":null,"abstract":"Introduction: This study compared phenotypic methods and the 16S rRNA gene sequencing method to identify the genus and species of non-fermenting gram-negative bacilli isolated from blood culture samples. Objectives: The aim of this study was to evaluate the effectiveness of using the 16S rRNA gene sequencing method in detecting the genus and species of non-fermented gram-negative bacteria isolated from blood samples. Materials and Methods: A cross-sectional study was conducted from April 2019 to April 2020, including all patients who required sterile culture at AL Zahra and Kashani hospitals. Specimens were cultured in BACTEC and subjected to standard phenotypic methods. Subsequently, 16S rRNA gene sequencing was performed to detect gram-negative non-fermenting Bacillus bacteria at the genus and species level. A comparative evaluation was then conducted. Results: The study identified 30 bacteria. The 16S rRNA gene sequencing method observed that 83.3% of the diagnoses were Acinetobacter baumannii, while the phenotypic approach identified 86.7% as Acinetobacter. Conclusion: The results indicate a significant difference between the phenotypic method and 16S rRNA sequencing in detecting non-fermenting gram-negative bacilli (NFGNB).","PeriodicalId":13454,"journal":{"name":"Immunopathologia Persa","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69815261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The comparative survey of phenotypic methods and the BD Phoenix M50 automated microbiology system for detecting the genus of non-fermenting gram-negative bacteria isolated from blood samples in Isfahan, Iran 表型方法与BD Phoenix M50自动微生物系统检测伊朗伊斯法罕血液中非发酵革兰氏阴性菌属的比较研究

IF 0.8

Immunopathologia Persa Pub Date : 2023-07-29 DOI: 10.34172/ipp.2023.39483

Shahnaz Eskandari, E. Amini, A. Baradaran, S. Mobasherizadeh, S. Rostami, M. Derakhshan

{"title":"The comparative survey of phenotypic methods and the BD Phoenix M50 automated microbiology system for detecting the genus of non-fermenting gram-negative bacteria isolated from blood samples in Isfahan, Iran","authors":"Shahnaz Eskandari, E. Amini, A. Baradaran, S. Mobasherizadeh, S. Rostami, M. Derakhshan","doi":"10.34172/ipp.2023.39483","DOIUrl":"https://doi.org/10.34172/ipp.2023.39483","url":null,"abstract":"Introduction: A comparative study was conducted to identify the genus and species of non-fermenting gram-negative bacilli isolated from blood culture samples using phenotypic methods and the Phoenix method. Objectives: This study aimed to evaluate the Phoenix system compared to the currently available phenotypic process. Materials and Methods: This descriptive-analytical cross-sectional study evaluated 30 samples collected from 2019 to 2020 from patients at AL Zahra and Kashani hospitals who required blood cultures. The specimens were injected into BACTEC™. Positive cultures identified as non-fermenting gram-negative bacteria by the phenotypic method were included in the study and then evaluated using the Phoenix method to determine the genus and species of non-fermenting gram-negative bacteria. A comparison was then conducted. Results: The study identified 30 non-fermenting gram-negative bacteria. The Phoenix method revealed that 78.5% of the diagnoses were Acinetobacter, while the phenotypic approach identified 86.7% as Acinetobacter spp. Conclusion: The present study demonstrated a significant difference between the Phoenix and phenotypic methods in identifying the type of bacteria.","PeriodicalId":13454,"journal":{"name":"Immunopathologia Persa","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42463446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The correlation of estrogen and progesterone receptor expression with prognostic parameters in women with breast cancer 癌症雌、孕激素受体表达与预后参数的相关性

IF 0.8

Immunopathologia Persa Pub Date : 2023-07-29 DOI: 10.34172/ipp.2023.39486

Shahnaz Eskandari, A. Baradaran, Sarah Ghorbani, Parisa Masoumzade

{"title":"The correlation of estrogen and progesterone receptor expression with prognostic parameters in women with breast cancer","authors":"Shahnaz Eskandari, A. Baradaran, Sarah Ghorbani, Parisa Masoumzade","doi":"10.34172/ipp.2023.39486","DOIUrl":"https://doi.org/10.34172/ipp.2023.39486","url":null,"abstract":"Introduction: Progesterone and estrogen receptor (PR and ER) expression are considered the oldest biomarkers. The presentation of these markers can guide the treatment in breast cancer patients because of their predictive value in hormonal therapy responsiveness and prognosis. Objectives: This study investigated the correlation between estrogen and PR expression with prognostic parameters of breast cancer, including age, grading, staging, tumor size, and lymph node spread. Patients and Methods: This cross-sectional study included 245 cases of breast tumors. Characteristics of patients, including age, the status of ER and PR biomarkers, tumor type, pathological features of cancer, and staging, were documented from case files. Accordingly, SPSS version 27 software was conducted for data analysis. The collected data were analyzed using the Spearman’s correlation, Mann-Whitney U and chi-squared tests. A P value < 0.05 is considered statistically significant. Results: High ER and PR expression (>50%) were found in 56.7% and 40.4% of cases, respectively. Most of the tumors in patients belonged to grade 2 (56.3%) and staging IIA, IIB, and IIIA. We found a significant correlation between ER expression, breast cancer grading, and patients’ age. PR expression was significantly associated with breast cancer staging, grading, size, and lymph node spread. Conclusion: These results highlight the value of ER and PR expression as they can determine the clinicopathological parameters of the tumor, which can be helpful for better-managing breast cancer.","PeriodicalId":13454,"journal":{"name":"Immunopathologia Persa","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44158211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of hemoperfusion on treatment outcomes in COVID-19 patients with respiratory failure: a prospective study 血液灌流对新冠肺炎呼吸衰竭患者治疗结果的影响：一项前瞻性研究

IF 0.8

Immunopathologia Persa Pub Date : 2023-07-29 DOI: 10.34172/ipp.2023.38457

Effat Rafiee, Samad Ghodrati, Ayoub Pezeshgi, Masumeh Hasanlu, F. Salarpour, Kamyar Mansori, N. Parsamanesh

{"title":"The effect of hemoperfusion on treatment outcomes in COVID-19 patients with respiratory failure: a prospective study","authors":"Effat Rafiee, Samad Ghodrati, Ayoub Pezeshgi, Masumeh Hasanlu, F. Salarpour, Kamyar Mansori, N. Parsamanesh","doi":"10.34172/ipp.2023.38457","DOIUrl":"https://doi.org/10.34172/ipp.2023.38457","url":null,"abstract":"Introduction: COVID-19 emerged as a global clinical threat following an outbreak in China in late 2019. Objectives: The aim of the current study was to assess the effect of hemoperfusion in COVID-19 patients with respiratory failure. Patients and Methods: In this prospective study, a total of 98 patients over the age of 18 with the positive COVID-19 polymerase chain reaction (PCR) test were investigated. The patients were divided into two groups; a control group consisting of 47 patients who did not receive hemoperfusion, and an exposed group consisting of 51 patients who met the criteria for hemoperfusion. Various parameters including complete blood cell counts, serum bilirubin, creatinine, C-reactive protein (CRP), and interleukin 6 (IL-6) levels were evaluated in all patients. Results: The results of our study revealed a statistically significant difference in intensive care unit (ICU) admission between the two groups. Hospitalization time (19.941±1.75 versus 14.615±1.39, P=0.021) and ICU time (14.98±1.30 versus 9.62±1.15; P=0.003) were significantly higher in patients who received hemoperfusion. Regarding the mortality rate, only 36.7% of the patients survived; however, there was no significant difference observed between the two groups (P=0.34). Conclusion: In conclusion, the findings of our study indicate that hemoperfusion in COVID-19 patients with respiratory failure led to a significant increase in hospital stay and ICU stay compared to those without hemoperfusion. Further research is needed to determine the optimal timing and frequency of hemoperfusion to improve treatment outcomes in COVID-19 patients with respiratory failure.","PeriodicalId":13454,"journal":{"name":"Immunopathologia Persa","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48215374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prognostic and diagnostic roles of serum ferritin level in cancer 血清铁蛋白水平对癌症的预后和诊断作用

IF 0.8

Immunopathologia Persa Pub Date : 2023-07-04 DOI: 10.34172/ipp.2023.40529

M. Barahman, Najmeh Nameh Goshay Fard, M. Bahadoram, E. Akade, Roozbeh Mohghaddar

引用次数: 0

Recurrent cardiac hydatid cysts with pericardial protrusion; a rare case presentation of Echinococcus granulosus 复发性心脏棘球蚴囊肿伴心包突出；细粒棘球蚴的罕见病例报告

IF 0.8

Immunopathologia Persa Pub Date : 2023-06-20 DOI: 10.34172/ipp.2023.31376

Mahmoud Beheshti Monfared, H. Ghaderi, Zahra Ansari Aval, M. Hekmat, S. Mirjafari, Reza Beheshti Monfared, R. Tirdad

{"title":"Recurrent cardiac hydatid cysts with pericardial protrusion; a rare case presentation of Echinococcus granulosus","authors":"Mahmoud Beheshti Monfared, H. Ghaderi, Zahra Ansari Aval, M. Hekmat, S. Mirjafari, Reza Beheshti Monfared, R. Tirdad","doi":"10.34172/ipp.2023.31376","DOIUrl":"https://doi.org/10.34172/ipp.2023.31376","url":null,"abstract":"Hydatid cyst (HC) is a rare pathology mostly found in less developed, livestock-raising countries. HC can be found anywhere in the body, however it is a rare finding in the heart, and its recurrence in the heart and pericardium is very rare. A 54-year-old woman who had undergone surgery for the removal of HC in another country 11 years before presented with shortness of breath and heaviness in the chest. The examinations and computerized tomography (CT) scan revealed a large mass measuring 60×50 mm in the pericardium cavity originating from the right atrial wall. Infection with Echinococcus granulosus was confirmed with serological enzyme-linked immunosorbent assay (ELISA) test and the patient underwent cardiac surgery. The patient underwent cardiopulmonary bypass, nevertheless did not suffer cardiac arrest, and aortic cross-clamping was not performed for her. The removed mass was filled with daughter cysts. The endocysts were removed and intramural cysts were drained. Following the surgery, the patient received treatment with albendazole for six months. Cardiac hydatid cyst recurrence is a rare but possible incident, and annual follow-ups and echocardiography are recommended.","PeriodicalId":13454,"journal":{"name":"Immunopathologia Persa","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49181754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between placental thickness, grading, and heterogeneity in fetal growth restriction in the third trimester of pregnancy by ultrasonography and pathology tests and their relationship with estimated fetal weight and neonatal outcome 超声和病理检查显示的妊娠晚期胎儿生长受限胎盘厚度、分级和异质性之间的关系及其与估计胎儿体重和新生儿结局的关系

IF 0.8

Immunopathologia Persa Pub Date : 2023-06-17 DOI: 10.34172/ipp.2023.39471

F. Farahbod, E. Zarean, S. Khanjani, M. Moezzi, Fereshteh Mohammadizadeh, S. Shabanian

{"title":"Relationship between placental thickness, grading, and heterogeneity in fetal growth restriction in the third trimester of pregnancy by ultrasonography and pathology tests and their relationship with estimated fetal weight and neonatal outcome","authors":"F. Farahbod, E. Zarean, S. Khanjani, M. Moezzi, Fereshteh Mohammadizadeh, S. Shabanian","doi":"10.34172/ipp.2023.39471","DOIUrl":"https://doi.org/10.34172/ipp.2023.39471","url":null,"abstract":"Introduction: The placenta is the influencing factor on the fetal weight and is as the first organ that reveals the pathological changes of pregnancy. Therefore, placental ultrasound findings influence the diagnosis of fetal growth restriction (FGR). Objectives: This study examines the relationship between placental thickness, grading and heterogeneity during ultrasound and placental pathology in third trimester FGR fetuses and its effect on neonatal outcome. Patients and Methods: This prospective observational study included 67 pregnant women with FGR fetuses in the third trimester of pregnancy with the mean gestational age of 34.52 ± 2.65 weeks and possible termination of pregnancy within the next seven days. The placental thickness, grading, and heterogeneity in ultrasonography were examined and compared with thickness and grading. Their effect was also considered in neonatal outcome and the results were analyzed. Results: In this study, there is a significant relationship between the thickness of the placenta before and after birth with the weight of the placenta, weight and Apgar score, neonatal arterial pH at birth and fetal growth restriction grading in ultrasound, and neonatal outcome. Conclusion: This study shows that ultrasonic placental findings can be effective in determining the final weight of the placenta and fetus and also the final outcome of the baby at birth. Therefore, ultrasound of the placenta should be performed along with pregnancy ultrasound.","PeriodicalId":13454,"journal":{"name":"Immunopathologia Persa","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45391928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0