IEEE transactions on ultrasonics, ferroelectrics, and frequency control最新文献

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Remote Super-Resolution Mapping of Wave Fields 波场的远程超分辨率映射。
IF 3 2区 工程技术
IEEE transactions on ultrasonics, ferroelectrics, and frequency control Pub Date : 2025-02-04 DOI: 10.1109/TUFFC.2025.3538607
Jian-Yu Lu
{"title":"Remote Super-Resolution Mapping of Wave Fields","authors":"Jian-Yu Lu","doi":"10.1109/TUFFC.2025.3538607","DOIUrl":"10.1109/TUFFC.2025.3538607","url":null,"abstract":"Mapping wave field in space has many applications such as optimizing design of radio antennas, improving and developing ultrasound transducers, and planning and monitoring the treatment of tumors using high-intensity focused ultrasound (HIFU). Currently, there are methods that can map wave fields remotely or locally. However, there are limitations to these methods. For example, when mapping the wave fields remotely, the spatial resolution is limited due to a poor diffraction-limited resolution of the receiver, especially when the f-number of the receiver is large. To map the wave fields locally, the receiver is either subject to damage in hazardous environments (corrosive media, high temperature, high wave intensity, and so on) or difficult to be placed inside an object. To address these limitations, in this article, the point spread function (PSF)-modulation super-resolution imaging method was applied to map pulse ultrasound wave fields remotely at a high spatial resolution, overcoming the diffraction limit of a focused receiver. For example, to map a pulse ultrasound field of a full-width-at-half-maximum (FWHM) beamwidth of 1.24 mm at the focal distance of a transmitter, the FWHM beamwidths of the super-resolution mapping of the pulse wave field with a spherical glass modulator of 0.7 mm diameter at two receiver angles (0° and 45°) were about 1.13 and 1.22 mm, respectively, which were close to the theoretical value of 1.24 mm and were much smaller than the diffraction-limited resolution (1.81 mm) of the receiver. Without using the super-resolution method to remotely map the same pulse wave field, the FWHM beamwidth was about 2.06 mm. For comparison, the FWHM beamwidth obtained with a broadband (1–20 MHz) and 0.6-mm-diameter polyvinylidene fluoride (PVDF) needle hydrophone was about 1.41 mm. In addition to the focused pulse ultrasound wave field, a pulse Bessel beam near the transducer surface was mapped remotely with the super-resolution method, which revealed high spatial frequency components of the beam.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 3","pages":"370-379"},"PeriodicalIF":3.0,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143541851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MM-UKAN++: A Novel Kolmogorov–Arnold Network-Based U-Shaped Network for Ultrasound Image Segmentation 基于Kolmogorov-Arnold网络的u形网络超声图像分割。
IF 3 2区 工程技术
IEEE transactions on ultrasonics, ferroelectrics, and frequency control Pub Date : 2025-02-04 DOI: 10.1109/TUFFC.2025.3539262
Boheng Zhang;Haorui Huang;Yi Shen;Mingjian Sun
{"title":"MM-UKAN++: A Novel Kolmogorov–Arnold Network-Based U-Shaped Network for Ultrasound Image Segmentation","authors":"Boheng Zhang;Haorui Huang;Yi Shen;Mingjian Sun","doi":"10.1109/TUFFC.2025.3539262","DOIUrl":"10.1109/TUFFC.2025.3539262","url":null,"abstract":"Ultrasound (US) imaging is an important and commonly used medical imaging modality. Accurate and fast automatic segmentation of regions of interest (ROIs) in US images is essential for enhancing the efficiency of clinical and robot-assisted diagnosis. However, US images suffer from low contrast, fuzzy boundaries, and significant scale variations in ROIs. Existing convolutional neural network (CNN)-based and transformer-based methods struggle with model efficiency and explainability. To address these challenges, we introduce MM-UKAN++, a novel U-shaped network based on Kolmogorov-Arnold networks (KANs). MM-UKAN++ leverages multilevel KAN layers as the encoder and decoder within the U-network architecture and incorporates an innovative multidimensional attention mechanism to refine skip connections by weighting features from frequency-channel and spatial perspectives. In addition, the network effectively integrates multiscale information, fusing outputs from different scale decoders to generate precise segmentation predictions. MM-UKAN++ achieves higher segmentation accuracy with lower computational cost and outperforms other mainstream methods on several open-source datasets for US image segmentation tasks, including achieving 69.42% IoU, 81.30% Dice, and 3.31 mm HD in the BUSI dataset with 3.17 G floating point of operations (FLOPs) and 9.90 M parameters. The excellent performance on our automatic carotid artery US scanning and diagnostic system further proves the speed and accuracy of MM-UKAN++. Besides, the good performance in other medical image segmentation tasks reveals the promising applications of MM-UKAN++. The code is available on GitHub.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 4","pages":"498-514"},"PeriodicalIF":3.0,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143541848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Waveform-Specific Performance of Deep Learning-Based Super-Resolution for Ultrasound Contrast Imaging 基于深度学习的超分辨率超声对比成像的波形特性研究。
IF 3 2区 工程技术
IEEE transactions on ultrasonics, ferroelectrics, and frequency control Pub Date : 2025-01-30 DOI: 10.1109/TUFFC.2025.3537298
Rienk Zorgdrager;Nathan Blanken;Jelmer M. Wolterink;Michel Versluis;Guillaume Lajoinie
{"title":"Waveform-Specific Performance of Deep Learning-Based Super-Resolution for Ultrasound Contrast Imaging","authors":"Rienk Zorgdrager;Nathan Blanken;Jelmer M. Wolterink;Michel Versluis;Guillaume Lajoinie","doi":"10.1109/TUFFC.2025.3537298","DOIUrl":"10.1109/TUFFC.2025.3537298","url":null,"abstract":"Resolving arterial flows is essential for understanding cardiovascular pathologies, improving diagnosis, and monitoring patient condition. Ultrasound contrast imaging uses microbubbles to enhance the scattering of the blood pool, allowing for real-time visualization of blood flow. Recent developments in vector flow imaging further expand the imaging capabilities of ultrasound by temporally resolving fast arterial flow. The next obstacle to overcome is the lack of spatial resolution. Super-resolved ultrasound images can be obtained by deconvolving radiofrequency (RF) signals before beamforming, breaking the link between resolution and pulse duration. Convolutional neural networks (CNNs) can be trained to locally estimate the deconvolution kernel and consequently super-localize the microbubbles directly within the RF signal. However, microbubble contrast is highly nonlinear, and the potential of CNNs in microbubble localization has not yet been fully exploited. Assessing deep learning-based deconvolution performance for nontrivial imaging pulses is therefore essential for successful translation to a practical setting, where the signal-to-noise ratio (SNR) is limited, and transmission schemes should comply with safety guidelines. In this study, we train CNNs to deconvolve RF signals and localize the microbubbles driven by harmonic pulses, chirps, or delay-encoded pulse trains. Furthermore, we discuss potential hurdles for in vitro and in vivo super-resolution by presenting preliminary experimental results. We find that, whereas the CNNs can accurately localize microbubbles for all pulses, a short imaging pulse offers the best performance in noise-free conditions. However, chirps offer a comparable performance without noise, but they are more robust to noise and outperform all other pulses in low-SNR conditions.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 4","pages":"427-439"},"PeriodicalIF":3.0,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143541894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Delivery of Cavitation Therapy With a Modified Clinical Scanner: In Vitro Evaluation 用改良的临床扫描仪进行空化治疗:体外评估。
IF 3 2区 工程技术
IEEE transactions on ultrasonics, ferroelectrics, and frequency control Pub Date : 2025-01-29 DOI: 10.1109/TUFFC.2025.3536932
Lance H. De Koninck;Kaleb S. Vuong;Seonghun Shin;Jeffry E. Powers;Michalakis A. Averkiou
{"title":"Delivery of Cavitation Therapy With a Modified Clinical Scanner: In Vitro Evaluation","authors":"Lance H. De Koninck;Kaleb S. Vuong;Seonghun Shin;Jeffry E. Powers;Michalakis A. Averkiou","doi":"10.1109/TUFFC.2025.3536932","DOIUrl":"10.1109/TUFFC.2025.3536932","url":null,"abstract":"In this study, we design and implement pulses [1.67 MHz, 20–1000 cycles, 0.8–2.5 MPa, and 5–100 ms pulse repetition time (PRT)] suitable for microbubble cavitation treatments with a phased array of a clinical ultrasound scanner. A range of acoustic parameters was evaluated in a tissue-mimicking phantom with suspended Sonazoid microbubbles. Hydrophone measurements were used to optimize the transmit beamforming. A passive cavitation detection (PCD) system was designed to measure the microbubble scattered signals over a 1 s exposure. Postprocessing of the scattered signals evaluated frequency content to extract broadband energy and calculate the inertial cavitation dose (ICD). ICD was maximized at 1000 cycles (maximum pulse length), 5 ms (fastest firing rate), and 2.5 MPa peak negative pressure (PNP) (maximum pressure). Inertial cavitation was only sustained for about three pulses (out of hundreds fired) occurring within the first 100 ms of treatment. Temporal analysis of the first 1000-cycle pulse revealed that broadband energy is sustained for the entire pulse. We also demonstrate that while inertial cavitation is possible with clinically available pulse wave Doppler settings, ICD can be significantly increased using the new conditions suggested in this work. We have delivered successful image-guided cavitation treatment after modifying a clinical scanner and monitored the cavitation dose with a PCD system on a gel phantom with suspended microbubbles. We plan to apply this technique in vivo in animal tumor models next. This work demonstrates the first implementation of long, high-pressure pulses on a clinical scanner that users can optimize for cavitation treatments.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 3","pages":"351-361"},"PeriodicalIF":3.0,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143541882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Frequency-Domain Decoding of Cascaded Dual- Polarity Waves for Ultrafast Ultrasound Imaging 超快超声成像级联双极性波频域解码。
IF 3 2区 工程技术
IEEE transactions on ultrasonics, ferroelectrics, and frequency control Pub Date : 2025-01-28 DOI: 10.1109/TUFFC.2025.3534429
Charlotte L. Nawijn;Joosje M. K. de Bakker;Tim Segers;Chris L. de Korte;Michel Versluis;Anne E. C. M. Saris;Guillaume Lajoinie
{"title":"Frequency-Domain Decoding of Cascaded Dual- Polarity Waves for Ultrafast Ultrasound Imaging","authors":"Charlotte L. Nawijn;Joosje M. K. de Bakker;Tim Segers;Chris L. de Korte;Michel Versluis;Anne E. C. M. Saris;Guillaume Lajoinie","doi":"10.1109/TUFFC.2025.3534429","DOIUrl":"10.1109/TUFFC.2025.3534429","url":null,"abstract":"Ultrafast plane-wave (PW) ultrasound imaging is a versatile tool that has become increasingly relevant for blood flow imaging using speckle tracking but suffers from a low signal-to-noise ratio (SNR). Cascaded dual-polarity wave (CDW) imaging can improve the SNR by transmitting pulse trains, which are subsequently decoded to recover the imaging resolution. However, the current decoding method (in the time domain) requires a set of two acquisitions, which introduces motion artifacts that result in incorrect speckle tracking at high flow velocities. Here, we evaluate an inverse filtering approach that uses frequency-domain decoding to decode acquisitions independently. Experiments using a disk phantom show that frequency-domain decoding of a four-pulse train achieves an SNR gain of up to 4.2 dB, versus 5.9 dB for conventional decoding. The benefit of frequency-domain decoding for flow quantification is assessed through experiments performed with a rotating disk phantom and a parabolic flow, and through matching linear simulations. Both CDW methods improve the tracking accuracy compared to single PW imaging. Time-domain decoding outperforms frequency-domain decoding in low SNR conditions and low velocities (<inline-formula> <tex-math>$leq 0.25$ </tex-math></inline-formula> m/s), as a result of the higher SNR gain. In contrast, frequency-domain decoding outperforms time-domain decoding for high peak velocities in imaging of the rotating disk (1 m/s) and of the parabolic flow (2 m/s), when significant scatterer motion between acquisitions causes imperfect time-domain decoding. Its ability to decode individual acquisitions makes the used frequency-domain decoding of CDW (F-CDW) a promising approach to improve the SNR and thereby the accuracy of flow quantification at high velocities.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 3","pages":"321-337"},"PeriodicalIF":3.0,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=10856850","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143541884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control Publication Information IEEE超音波学、铁电学与频率控制论文集
IF 3 2区 工程技术
IEEE transactions on ultrasonics, ferroelectrics, and frequency control Pub Date : 2025-01-27 DOI: 10.1109/TUFFC.2025.3529339
{"title":"IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control Publication Information","authors":"","doi":"10.1109/TUFFC.2025.3529339","DOIUrl":"https://doi.org/10.1109/TUFFC.2025.3529339","url":null,"abstract":"","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 1","pages":"C2-C2"},"PeriodicalIF":3.0,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=10855164","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143107106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spatially Weighted Fidelity and Regularization Terms for Attenuation Imaging 衰减成像的空间加权保真度和正则化项。
IF 3 2区 工程技术
IEEE transactions on ultrasonics, ferroelectrics, and frequency control Pub Date : 2025-01-27 DOI: 10.1109/TUFFC.2025.3534660
Sebastian Merino;Roberto Lavarello
{"title":"Spatially Weighted Fidelity and Regularization Terms for Attenuation Imaging","authors":"Sebastian Merino;Roberto Lavarello","doi":"10.1109/TUFFC.2025.3534660","DOIUrl":"10.1109/TUFFC.2025.3534660","url":null,"abstract":"Quantitative ultrasound (QUS) holds promise in enhancing diagnostic accuracy. For attenuation imaging, the regularized spectral log difference (RSLD) can generate accurate local attenuation maps. However, the performance of the method degrades when significant changes in backscatter amplitude occur. Variations in the technique were introduced involving a weighted approach to backscatter regularization, which, however, is not effective when changes in both attenuation and backscatter are present. This study introduces a novel approach that incorporates an L1-norm for backscatter regularization and spatially varying weights for both fidelity and regularization terms. The weights are calculated from an initial estimation of backscatter changes. Comparative analyses with simulated, phantom, and clinical data were performed. When changes in backscatter and attenuation occur, the proposed approach reduced the lowest root mean square error by up to 73%. It also improved the contrast-to-noise ratio (CNR) by a factor of 4.4 on average compared with previously available methods, considering the simulated and phantom data. In vivo results from healthy livers, thyroid nodules, and a breast tumor further confirm its effectiveness. In the liver, it is shown to be effective at reducing artifacts of attenuation images. In thyroid and breast tumors, the method demonstrated an enhanced CNR and better consistency of the attenuation measurements with the posterior acoustic enhancement. Overall, this approach offers promise for enhancing ultrasound attenuation imaging by helping differentiate tissue characteristics that may indicate pathology.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 3","pages":"338-350"},"PeriodicalIF":3.0,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143541853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantification of Blood Flow in the Carotid Bifurcation of Healthy Subjects 健康受试者颈动脉分叉血流的定量分析。
IF 3 2区 工程技术
IEEE transactions on ultrasonics, ferroelectrics, and frequency control Pub Date : 2025-01-22 DOI: 10.1109/TUFFC.2025.3529285
Janna Ruisch;Joosje M. K. de Bakker;Majorie van Helvert;Erik Groot Jebbink;Suzanne Holewijn;Michel M. P. J. Reijnen;Chris L. de Korte;Anne E. C. M. Saris
{"title":"Quantification of Blood Flow in the Carotid Bifurcation of Healthy Subjects","authors":"Janna Ruisch;Joosje M. K. de Bakker;Majorie van Helvert;Erik Groot Jebbink;Suzanne Holewijn;Michel M. P. J. Reijnen;Chris L. de Korte;Anne E. C. M. Saris","doi":"10.1109/TUFFC.2025.3529285","DOIUrl":"10.1109/TUFFC.2025.3529285","url":null,"abstract":"Locally disturbed blood flow patterns are known to create an atherogenic environment, particularly in the presence of other cardiovascular risk factors. Given the geometry of a healthy carotid artery, complex flow patterns are expected to be present. This study aims to characterize (complex) blood flow patterns and estimate flow-derived parameters in the carotid bifurcation of healthy subjects. Ultrasound-based velocity vector imaging (US-VVI) was acquired in the carotid bifurcation of 20 healthy subjects. Hemodynamic parameters, including temporal velocity profile, vector complexity (VC), vortex presence, and wall shear stress (WSS), were derived and compared between two age groups (20–30 and 65–75 years). Lower velocities and higher VC values were observed in the older age group for all timepoints. The highest presence of vortices was observed during the systolic deceleration, which was more exposed in younger subjects (5 out of 10) compared to older subjects (3 out of 9). A quick build-up and consequent resolving of the vortices was reflected by the relatively short vortex duration, with a vortex presence of 11.4% (7.9–15.6) and 13.1% (5.9–18.6) as a percentage of the cardiac cycle in younger and older subjects, respectively. Larger WSS estimates, represented as median along the complete vessel wall, were found in the younger subjects at all timestamps, except at systolic deceleration. In conclusion, the presence of complex flow patterns was confirmed in healthy subjects and multiple flow-derived hemodynamic parameters were evaluated in two age groups, providing an insight into age-related differences in hemodynamics. Aging seemed to result in higher vector complexities, whereas the presence of recirculating flow is less in older subjects.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 3","pages":"309-320"},"PeriodicalIF":3.0,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=10849671","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143541850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Selective Subnucleus Ultrasound Stimulation Induces Synaptic Potentiation in the Mouse Hippocampus 选择性亚核超声刺激诱导小鼠海马突触增强。
IF 3 2区 工程技术
IEEE transactions on ultrasonics, ferroelectrics, and frequency control Pub Date : 2025-01-20 DOI: 10.1109/TUFFC.2025.3531971
Wei Zhou;Pengqi Li;Wen Meng;Stephanie Hong Zheng;Shixiong Zhang;Shasha Yi;Minghui Gao;Zhengrong Lin
{"title":"Selective Subnucleus Ultrasound Stimulation Induces Synaptic Potentiation in the Mouse Hippocampus","authors":"Wei Zhou;Pengqi Li;Wen Meng;Stephanie Hong Zheng;Shixiong Zhang;Shasha Yi;Minghui Gao;Zhengrong Lin","doi":"10.1109/TUFFC.2025.3531971","DOIUrl":"10.1109/TUFFC.2025.3531971","url":null,"abstract":"Ultrasound neuromodulation enables to elicit of long-lasting effect on neural activities and behavioral responses across species, including humans. However, the potential biophysical mechanism of ultrasound stimulation to induce neuroplasticity is still unclear. In this study, we developed a miniature, high target-specificity ultrasound neuro-stimulation chip to selectively stimulate subnucleus and investigate the synaptic plasticity induced by ultrasound stimulation in mouse hippocampal slices. The design of the narrow aperture planar interdigital transducers (IDTs) could reach a 1.3-mm acoustic beam to precisely stimulate the presynaptic CA3 neurons. Acoustic long-term potentiation (A-LTP) was induced by the ultrasound neuro-stimulation chip with 1-ms pulsed duration and different acoustic pressures at 100-Hz repetition frequency [100-Hz low-intensity pulsed ultrasound stimulation (LIPUS)] in the CA3 subregion. Synaptic plasticity was measured by the slope of field excitatory postsynaptic potentials (fEPSPs), which were elicited using bipolar electrical stimulation (ES) electrodes in the Schaffer collaterals of CA3 region and recorded in postsynaptic CA1 neurons using extracellular electrodes. The LTP induced by ultrasound was compared to conventional 100-Hz tetanic ES (100-Hz ES). Our results confirmed that ultrasound stimulation of CA3 significantly induces LTP-like synaptic plasticity when the applied acoustic pressure was 1.08 MPa. The success rate of A-LTP and the average weight of synaptic potentiation level were significantly increased with the increment of acoustic pressure. Moreover, A-LTP was mainly due to the mechanical effects of acoustic waves, but not the thermal or cavitation effects. These results demonstrated that the high-precision ultrasound neuro-stimulation chip can selectively modulate the neural activities in the subnuclear brain region to induce synaptic potentiation, clarifying the biophysical mechanism of A-LTP.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 4","pages":"454-466"},"PeriodicalIF":3.0,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143541852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Temperature Dependence of the Sensitivity of Hydrophones for Biomedical Ultrasound Exposimetry 生物医学超声暴露水听器灵敏度的温度依赖性。
IF 3 2区 工程技术
IEEE transactions on ultrasonics, ferroelectrics, and frequency control Pub Date : 2025-01-09 DOI: 10.1109/TUFFC.2025.3527625
Volker Wilkens;Martin Weber;Jennifer Twiefel
{"title":"Temperature Dependence of the Sensitivity of Hydrophones for Biomedical Ultrasound Exposimetry","authors":"Volker Wilkens;Martin Weber;Jennifer Twiefel","doi":"10.1109/TUFFC.2025.3527625","DOIUrl":"10.1109/TUFFC.2025.3527625","url":null,"abstract":"Though it has been recognized that the sensitivity of hydrophones depends on the temperature of the water they are used in, the amount of specific data that is available is very limited. This is possible because the measurements are technically challenging, laborious, and time-consuming. A broadband primary hydrophone calibration setup was extended to implement stable calibration conditions at different temperature settings. Four hydrophones of different types commonly used in ultrasound exposimetry were then characterized in the range from 17 °C to 29 °C, and average change rates of the sensitivity with temperature were determined for different ultrasonic frequencies. Two different membrane hydrophones showed an increase in sensitivity with increasing temperature in the range from 0.55% to 1.10% per 1 °C temperature rise within their bandwidths. The results for a capsule-type and a needle-type hydrophone were different in the sense that a decreasing sensitivity with increasing temperature was also observed. For the capsule-type hydrophone, a small increase was observed up to 15 MHz and a decrease for higher frequencies. The needle-type hydrophone provided a decrease at all frequencies, and the results were more noisy. Data, as determined in this study, can be applied to correct acoustic output measurements of medical ultrasonic equipment if the water temperature of the hydrophone application differs from that during calibration. Alternatively, it may suffice in some applications to consider a sensitivity change with temperature within the uncertainty estimation of the exposure measurement, in particular, if the temperature difference is limited to 1 °C or 2 °C.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 3","pages":"362-369"},"PeriodicalIF":3.0,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143541855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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