Indian pediatricsPub Date : 2025-09-01Epub Date: 2025-07-22DOI: 10.1007/s13312-025-00135-0
Rajan Kumar, Ehtesham Ansari
{"title":"Community-Based Study on Childhood Injuries in Rural Odisha.","authors":"Rajan Kumar, Ehtesham Ansari","doi":"10.1007/s13312-025-00135-0","DOIUrl":"10.1007/s13312-025-00135-0","url":null,"abstract":"","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"710"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144690071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Utility of Fecal Biomarkers to Predict Invasive Nature of Acute Infectious Diarrhea in Indian Children.","authors":"Prabhav Aggarwal, Raghvendra Singh, Masoom Nathani, Sonal Saxena, Oves Siddiqui","doi":"10.1007/s13312-025-00030-8","DOIUrl":"10.1007/s13312-025-00030-8","url":null,"abstract":"<p><strong>Objective: </strong>To determine role of fecal calprotectin (FC) and fecal lactoferrin (FL) in diagnosis of invasive diarrhea.</p><p><strong>Methods: </strong>Stool samples from 75 children (≤ 12 years) with acute diarrhea were analysed using wet mount microscopy, culture, multiplex polymerase chain reaction, rapid tests for Rotavirus/ Adenovirus and quantitative ELISA for FC and FL.</p><p><strong>Results: </strong>The mean (SD) FC levels (μg/g) [774 (626.59) vs. 213 (251.48), P < 0.001] and FL levels (μg/g) [7.95 (4.72) vs. 4.22 (3.91), P = 0.004] were significantly higher in children with invasive diarrhea (n = 38) compared to those with non-invasive diarrhea (n = 37). Cut-off values of FC > 243 μg/g (sensitivity 81.57%, specificity 67.56%, AUC 0.813) and for FL > 6.02 μg/g (sensitivity 71.05%, specificity 81.08%, AUC 0.732) have diagnostic potential.</p><p><strong>Conclusions: </strong>FC and FL can aid diagnosis of acute invasive diarrhea.</p>","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"671-675"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143779901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Indian pediatricsPub Date : 2025-08-27DOI: 10.1007/s13312-025-00179-2
R M Dinesh Babu, G S Naresh Kanna, Muthu Meera, S Ashwath
{"title":"Thiamine-Responsive Megaloblastic Anemia Syndrome: A Rare Syndromic Cause of Diabetes in Childhood.","authors":"R M Dinesh Babu, G S Naresh Kanna, Muthu Meera, S Ashwath","doi":"10.1007/s13312-025-00179-2","DOIUrl":"https://doi.org/10.1007/s13312-025-00179-2","url":null,"abstract":"","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Indian pediatricsPub Date : 2025-08-27DOI: 10.1007/s13312-025-00171-w
Kanya Mukhopadhyay, Rajni Sharma, Jaivinder Yadav
{"title":"Cognitive Functions and Behavioral Outcomes of Very Low Birth Weight Neonates in Middle Childhood.","authors":"Kanya Mukhopadhyay, Rajni Sharma, Jaivinder Yadav","doi":"10.1007/s13312-025-00171-w","DOIUrl":"https://doi.org/10.1007/s13312-025-00171-w","url":null,"abstract":"<p><strong>Objective: </strong>To assess the cognitive and behavioral outcomes of very low birth weight (VLBW) as compared to normal birth weight (NBW) neonates in middle childhood.</p><p><strong>Methods: </strong>In this observational study, the first 50 VLBW (≤ 1250 g) children from an original cohort of 2009-2011, who agreed to participate, and 50 age and sex-matched NBW children were assessed at 6-11 years age. Cognitive function, behavior, psychopathology, self-concept, adjustment and memory parameters were assessed by a certified psychologist using Malin's Intelligence Scale for Indian Children (MISIC), Childhood Psychopathology Measurement Schedule, Children's Self-concept Scale, Preadolescent Adjustment Inventory, and PGI Memory Scale for Children (PGIMC), respectively.</p><p><strong>Results: </strong>Compared to NBW, the VLBW children had significantly lower Verbal Intelligence Quotient (IQ) (P = 0.008), Performance IQ (P < 0.001), and Full-Scale IQ (FSIQ) (P < 0.001). VLBW cohort had significantly lower scores in remote memory (P < 0.001), mental balance (P = 0.001), attention (P = 0.005), visual retention (P < 0.001), and recognition (P = 0.003). VLBW cohort exhibited significantly higher scores on psychopathology (P = 0.036), anxiety (P = 0.034), significantly lower self-concept (P < 0.001) and adjustment scores (P < 0.001) than NBW.</p><p><strong>Conclusions: </strong>VLBW children have significant cognitive, behavioral and adjustment issues as compared to NBW children.</p>","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Indian pediatricsPub Date : 2025-08-19DOI: 10.1007/s13312-025-00159-6
Rachit Khandelwal, Sumaira Khalil, Vipin Tyagi, Mrinalini Kotru, Basu Dev Banerjee, Sunil Gomber, Pooja Dewan
{"title":"Organochlorine Pesticide Residues in Children with Hematological Disorders.","authors":"Rachit Khandelwal, Sumaira Khalil, Vipin Tyagi, Mrinalini Kotru, Basu Dev Banerjee, Sunil Gomber, Pooja Dewan","doi":"10.1007/s13312-025-00159-6","DOIUrl":"10.1007/s13312-025-00159-6","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the levels of organochlorine pesticide (OCP) residues in sera and bone marrow of children with malignant and non-malignant hematological disorders (HDs) with those in healthy controls.</p><p><strong>Methods: </strong>This case-control study was conducted among children aged ≤ 12 years with malignant and non-malignant HDs and non-anemic healthy controls. Children with gross congenital malformations, neurodevelopmental disorders, and chronic systemic diseases were excluded. OCPs were estimated in sera and bone marrow aspirate using gas-liquid chromatography/<sup>63</sup>Ni electron capture detection.</p><p><strong>Results: </strong>Thirty children, each, with malignant HDs, non-malignant HDs, and controls, were included. The median (Q1, Q3) serum total OCPs (ng/mL) were significantly higher in children with malignant and non-malignant HDs compared to controls [38.67 (33.64, 42.51); 32.72 (17.26, 41.60); and 14.11 (12.82, 16.40)]; levels were significantly higher in the malignant versus non-malignant HD group. The median (Q1, Q3) serum levels of total hexachlorocyclohexane [3.30 (2.23, 4.28) vs. 2.16 (1.31, 3.31) ng/mL] and β-hexachlorocyclohexane [0.98 (0.67, 1.68) vs. 0.54 (0.10, 0.77) ng/mL] levels were significantly higher in children with non-malignant HDs compared to malignant HD, respectively. The median (Q1, Q3) total bone marrow OCPs (ng/mL) were significantly higher in the malignant HD group [23.53 (20.83, 26.91)] compared to the non-malignant HD group [17.41 (0, 25.63)]; bone marrow endosulfan II (ng/mL) was significantly higher in the non-malignant HD group [1.56 (0.56, 3.89)] compared to malignant HD group [0.45 (0.35, 1.72)].</p><p><strong>Conclusion: </strong>Children with HDs had significantly higher OCP residues in sera compared to controls. The cumulative OCP residues in sera and bone marrow were significantly higher in children with malignant versus non-malignant HDs.</p>","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144872918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Indian pediatricsPub Date : 2025-08-18DOI: 10.1007/s13312-025-00172-9
G M Pranam, Usha Hirevenkangoudar, Sanjeev Chetty, Srikesh Laguvaram
{"title":"Unmasking a Rare Cause of Macrocytic Anemia and Proteinuria in a Child.","authors":"G M Pranam, Usha Hirevenkangoudar, Sanjeev Chetty, Srikesh Laguvaram","doi":"10.1007/s13312-025-00172-9","DOIUrl":"https://doi.org/10.1007/s13312-025-00172-9","url":null,"abstract":"","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144872920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Indian pediatricsPub Date : 2025-08-18DOI: 10.1007/s13312-025-00169-4
Anurag V Kumar, Narayanan Parameswaran
{"title":"Should Amoxicillin-Clavulanate and Not Amoxicillin be the Choice of Antibiotic for Uncomplicated Community-Acquired Pneumonia? No.","authors":"Anurag V Kumar, Narayanan Parameswaran","doi":"10.1007/s13312-025-00169-4","DOIUrl":"https://doi.org/10.1007/s13312-025-00169-4","url":null,"abstract":"","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144872919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Indian pediatricsPub Date : 2025-08-12DOI: 10.1007/s13312-025-00168-5
Lian-Sheng Zhong, Yao Wu, Jia-Liang Zou
{"title":"Bloody Montgomery's Tubercle Discharge in an Infant.","authors":"Lian-Sheng Zhong, Yao Wu, Jia-Liang Zou","doi":"10.1007/s13312-025-00168-5","DOIUrl":"https://doi.org/10.1007/s13312-025-00168-5","url":null,"abstract":"","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144821365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Indian pediatricsPub Date : 2025-08-12DOI: 10.1007/s13312-025-00170-x
Rashna Dass
{"title":"Should Amoxicillin-Clavulanate and Not Amoxicillin be the Choice of Antibiotic for Uncomplicated Community Acquired Pneumonia? Yes.","authors":"Rashna Dass","doi":"10.1007/s13312-025-00170-x","DOIUrl":"https://doi.org/10.1007/s13312-025-00170-x","url":null,"abstract":"","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144821370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}