Indian pediatrics最新文献_第10页

Serum Ferritin Levels in Very Preterm Infants Receiving Erythrocyte Transfusions: A Retrospective Study. 接受红细胞输注的早产儿血清铁蛋白水平：一项回顾性研究

IF 1.7 4区医学

Indian pediatrics Pub Date : 2024-07-15 Epub Date: 2024-06-07

Arathy Vijay, Zubair Ahmad Bhat, Femitha Pournami, Arif Abdulsalam Kolisambeevi, Naveen Jain

引用次数: 0

Comparative Evaluation of Multiplex PCR, RLEP PCR and LAMP PCR in Urine, Stool and Blood Samples for the Diagnosis of Pediatric Leprosy - A Cross-Sectional Study. 尿液、粪便和血液样本中多重 PCR、RLEP PCR 和 LAMP PCR 用于诊断小儿麻风病的比较评估--一项横断面研究。

IF 1.7 4区医学

Indian pediatrics Pub Date : 2024-07-15 Epub Date: 2024-06-13

Shivam Sharma, Rajeshwar Dayal, Raj Kamal, Dharmendra Singh, Shripad A Patil, Neeraj Kumar, Sheo Pratap Singh, Madhu Nayak

{"title":"Comparative Evaluation of Multiplex PCR, RLEP PCR and LAMP PCR in Urine, Stool and Blood Samples for the Diagnosis of Pediatric Leprosy - A Cross-Sectional Study.","authors":"Shivam Sharma, Rajeshwar Dayal, Raj Kamal, Dharmendra Singh, Shripad A Patil, Neeraj Kumar, Sheo Pratap Singh, Madhu Nayak","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To compare the diagnostic efficacy of multiplex polymerase chain reaction (PCR), Mycobacterium leprae-specific repetitive element (RLEP) PCR and loop-mediated isothermal amplification (LAMP) PCR in the diagnosis of pediatric leprosy as an alternative to slit-skin smear (SSS) examination.Methods: A cross-sectional study was performed on 26 children aged 0-18 years with characteristic skin lesions of leprosy. SSS examination for acid fast bacilli (AFB) was performed for all children. Additionally, urine, stool and blood samples were tested by three PCR techniques - multiplex, RLEP and LAMP. The results of these tests were compared with each other and with results of SSS examination for acid fast bacilli (AFB) using appropriate statistical tests.Results: Out of 26 patients studied, SSS examination was positive for AFB in 7 cases (26.9%). In blood samples, the positivity of multiplex PCR, RLEP PCR and LAMP PCR was 84.6%, 80.8%, and 80.8%, respectively. Multiplex PCR in blood samples was positive in 100% (n = 7) of SSS positive cases and 84.2% (16 out of 19) of the SSS negative cases (P < 0.001). The positivity of all PCR methods in urine and stool samples was significantly lesser than in blood.Conclusion: Multiplex PCR in blood sample is a superior diagnostic tool for pediatric leprosy compared to RLEP PCR and LAMP PCR as well as SSS examination.","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"661-665"},"PeriodicalIF":1.7,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141442556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recommending Adoption of Revised Growth Charts for Indian Children is Misleading: Authors's Reply. 建议采用经修订的印度儿童成长图表具有误导性：作者的回复。

IF 1.7 4区医学

Indian pediatrics Pub Date : 2024-07-15

Santu Ghosh, Harshpal Singh Sachdev

引用次数: 0

Biomonitoring Study of Urinary Bisphenol A Levels and Impact of Bottle-Feeding Practices Among Infants and Children From Northern India. 印度北部婴幼儿尿液中双酚 A 含量及奶瓶喂养方式影响的生物监测研究

IF 1.7 4区医学

Indian pediatrics Pub Date : 2024-07-15 Epub Date: 2024-05-25

Prabakaran Gangadaran, Bhavneet Bharti, Savita Verma Attri, Vivek Singh Malik, Ajay Patial

{"title":"Biomonitoring Study of Urinary Bisphenol A Levels and Impact of Bottle-Feeding Practices Among Infants and Children From Northern India.","authors":"Prabakaran Gangadaran, Bhavneet Bharti, Savita Verma Attri, Vivek Singh Malik, Ajay Patial","doi":"","DOIUrl":"","url":null,"abstract":"Objectives: To compare the urinary bisphenol A (BPA) levels in bottle-fed and never bottle-fed infants and under-five children and to determine the impact of bottle-feeding practices and sociodemographic factors on urinary BPA levels.Methods: A community-based cross-sectional study was carried out on children aged between 2 to 60 months attending the Anganwadi centres in Chandigarh.Results: Urine samples were collected from 184 children, out of which 94.56% (n = 174) children had detectable urinary BPA levels. The mean (SD) BPA level was 2.74 (2.60) ng/ml and BPA was detected in 93.9% of 'ever' bottle-fed children (n = 93/99) and 95.3% of 'never' bottle-fed children (n = 81/85) (P = 0.69). On multivariate regression analysis, there were no significant predictors for high (≥ 75th percentile) urinary BPA levels. Still, the odds of urinary BPA levels ≥75th percentile showed higher trend for significance among children from middle/higher socioeconomic background in reference to lower socioeconomic stratum (adjusted OR 7.02; 95% CI 1.24, 133.25; P = 0.07) and among children whose feeding bottles were brushed once or twice daily in reference to group with no daily brushing (adjusted OR 3.92, 95% CI 0.95, 20.56; P = 0.07).Conclusions: Although feeding with plastic bottle did not emerge as a statistically significant risk factor for BPA exposure, yet detection of BPA levels among majority of study children signals urgent need for unmasking exposure to other sources given the potential long-term toxicity of BPA among infants and young children.","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"649-655"},"PeriodicalIF":1.7,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141158389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Assisted Reproductive Technology Act 2021- Provisions and Implications. 2021 年辅助生殖技术法》--条款和影响。

IF 1.7 4区医学

Indian pediatrics Pub Date : 2024-07-15 Epub Date: 2024-05-25

Mamatha Gowda, Bobbity Deepthi, Kubera Siddappa Nichanahalli

引用次数: 0

Weight Velocity Percentiles in Children Aged 4-17 Years from Pune During 2007-2013. 2007-2013 年间浦那 4-17 岁儿童的体重速度百分位数。

IF 1.7 4区医学

Indian pediatrics Pub Date : 2024-07-15 Epub Date: 2024-04-22

Vaman Khadilkar, Chirantap Oza, Sushil Yewale, Anuradha Khadilkar

{"title":"Weight Velocity Percentiles in Children Aged 4-17 Years from Pune During 2007-2013.","authors":"Vaman Khadilkar, Chirantap Oza, Sushil Yewale, Anuradha Khadilkar","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To assess weight velocity and the age at peak weight velocity and to construct weight velocity percentiles in 4-17-year-old apparently healthy Indian children.Method: This longitudinal study enrolled 1045 children (588 boys) from Pune belonging to middle and upper socioeconomic class aged 4-17 years. The study parameters included annual height and weight measurements recorded longitudinally from 2007 to 2013. A total of 5225 weight velocity measurements (2940 on boys) were computed. Age- and gender-specific smoothened weight velocity percentiles (3rd, 10th, 25th, 50th, 75th, 90th and 97th) were constructed using LMS chart maker.Results: The median weight velocity was low in boys and girls at 4 years, thereafter it increased to a peak of 4.6 kg/year at 13 years in boys, then declined to 1.1 kg/year at 17.5 years. In girls, median weight velocity peaked to 4.0 kg/year at 11 years, then declined to 0.8 kg/year at 17.5 years. Peak velocity-centred analysis revealed higher peak velocities of 7.5 kg/year at 13.1 years and 6.6 kg/year at 12 years in boys and girls respectively.Conclusion: Weight velocity percentiles are presented for 4-17-year-old apparently healthy Indian children.","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"637-642"},"PeriodicalIF":1.7,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140851367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative Efficacy of Ferrous, Ferric and Liposomal Iron Preparations for Prophylaxis in Infants. 用于婴儿预防的亚铁、铁和脂质体铁制剂的功效比较。

IF 1.7 4区医学

Indian pediatrics Pub Date : 2024-07-15 Epub Date: 2024-04-22

Betül Orhan Kiliç, Dilek Konuksever, Namik Yasar Özbek

{"title":"Comparative Efficacy of Ferrous, Ferric and Liposomal Iron Preparations for Prophylaxis in Infants.","authors":"Betül Orhan Kiliç, Dilek Konuksever, Namik Yasar Özbek","doi":"","DOIUrl":"","url":null,"abstract":"Objective: This study aimed to assess the efficacy of different oral iron preparations prescribed for prevention of iron deficiency anemia in healthy infants.Methods: This retrospective study enrolled infants aged between 6 and 12 months who were initiated on iron prophylaxis at four months of age. Enrolled children consistently used specific iron preparations (ferrous, ferric or liposomal iron) and had their complete blood counts and serum ferritin levels assessed within the 6-12 month timeframe. Blood values and iron prophylaxis type (ferrous (Fe+2), ferric (Fe+3), liposomal iron) were recorded. Chi-square test was used to compare the hemoglobin and ferritin levels levels between groups. Univariate and multivariate regression analyses assessed the risk of anemia.Results: The study included 371 children (ferrous sulphate - 60, iron hydroxide-polymaltose complex - 137 and liposomal ferric pyrophosphate - 174) with a mean (SD) age 9.1 (1.3) mo. Iron deficiency in different groups were: liposomal iron (46.0%), ferric iron (44.5%), and ferrous iron (5.0%). Mean (SD) serum ferritin levels (µg/L) were higher in the ferrous group [30.1 (10.8)] compared to infants receiving ferric [17.6 (14.50)] and liposomal iron [15.4 (12.1)] (P < 0.001). Mean (SD) hemoglobin levels (g/dL) were significantly higher in the ferrous group [12.4 (0.8)] compared to ferric [11.9 (1.1)] and liposomal iron group [12.0 (1.1)]; P =0.008. Multiple regression analysis showed that ferrous group was associated with a lower risk of iron deficiency [OR (95% CI) 0.04 (0.01-0.15), P < 0.001].Conclusion: Ferrous iron demonstrated superior efficacy compared to ferric and liposomal iron. Further studies are needed to establish alternative iron preprations in children.","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"621-626"},"PeriodicalIF":1.7,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140864031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of COVID-19 Pandemic on Routine Immunization Among Tribal Children in Odisha: A Rapid Epidemiological Survey. COVID-19 大流行对奥迪沙部落儿童常规免疫接种的影响：快速流行病学调查。

IF 1.7 4区医学

Indian pediatrics Pub Date : 2024-07-15 Epub Date: 2024-05-25

G Alekhya, Dinesh Prasad Sahu, Binod Kumar Patro, Priyamadhaba Behera, Manish Taywade, Sankalp Suhag Dash

{"title":"Impact of COVID-19 Pandemic on Routine Immunization Among Tribal Children in Odisha: A Rapid Epidemiological Survey.","authors":"G Alekhya, Dinesh Prasad Sahu, Binod Kumar Patro, Priyamadhaba Behera, Manish Taywade, Sankalp Suhag Dash","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To assess the impact of COVID-19 on immunization coverage and delayed vaccination among tribal children in the Khordha district of Odisha state.Methods: A cross-sectional rapid epidemiological survey was conducted using a standard WHO (30 × 7) cluster survey with 30 tribal villages under the Community Health Centre (CHC), Mendhasala, Odisha, as clusters and seven children from each cluster. A total of 14 children from each cluster; seven each born in 2019 (2019 cohort) and 2020 (2020 cohort), amounting to 420 children were included. The dates of vaccination and related details were obtained from the mother and child protection cards alongside a pretested, semi-structured questionnaires administered to the mothers or primary caregivers. Immunization coverage and delayed vaccination rates were compared between the two cohorts.Results: Full immunization coverage was 81.9% and 77.6% in the 2019 and 2020 cohorts, respectively. A significant decline in full immunization coverage was seen for 14 weeks (Pentavalent-3) vaccine in 2020 cohort (P = 0.01). The proportion of delayed vaccination for scheduled vaccines at birth, 6 weeks, 10 weeks, 14 weeks, and 9-12 months for 2019 cohort and 2020 cohort were 8.6%, 6.7%, 18.1%, 19.5%, 22.4%, and 21.9%, 26.7%, 30.5%, 19%, 16.2%, respectively. However, delayed vaccination rates among the 2019 and 2020 cohorts were not statistically significant.Conclusion: Our study findings showed a little decline in immunization coverage in tribal areas during the pandemic.","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"627-631"},"PeriodicalIF":1.7,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141158390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic Accuracy of Waist Circumference and Waist-to-Height Ratio for Moderate and Severe Acute Malnutrition in Under-5 Children. 腰围和腰围身高比对 5 岁以下儿童中度和严重急性营养不良的诊断准确性。

IF 1.7 4区医学

Indian pediatrics Pub Date : 2024-07-15 Epub Date: 2024-04-05

Vaishali Sharma, Sumaira Khalil, Dheeraj Shah, Piyush Gupta

{"title":"Diagnostic Accuracy of Waist Circumference and Waist-to-Height Ratio for Moderate and Severe Acute Malnutrition in Under-5 Children.","authors":"Vaishali Sharma, Sumaira Khalil, Dheeraj Shah, Piyush Gupta","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To determine the most appropriate cut-off values of Waist Circumference (WC) and Waist-to-Height Ratio (WHtR) for diagnosing moderate acute malnutrition (MAM) and severe acute malnutrition (SAM) in under-five children.Methods: This cross-sectional diagnostic accuracy study was conducted between January 2021 and August 2022 in the Department of Pediatrics of a tertiary hospital in Delhi. Children aged 6 months to 5 years attending the outpatient or emergency services were included in the study. Detailed clinical evaluation and anthropometry including measurement of WC were done at enrollment. Body mass index (BMI) and WHtR were calculated. Malnutrition was classified as per the WHO criteria. Receiver operating characteristic curves (sensitivity, specificity) for WC and WHtR (absolute values) were drawn against the standard test of WHO definitions for MAM and SAM to determine the most appropriate cut-offs for diagnosing MAM and SAM.Results: 1500 children with a median (IQR) age of 29 (14, 43) months were enrolled; 21% children had MAM and 11% had SAM as per the WHO criteria. WC < 44.5 cm (sensitivity 74.1%, specificity 71.1%) and WHtR < 0.565 (sensitivity 75.6%, specificity 33.7%) were the best cut-offs to identify MAM, whereas WC < 42.3 cm (sensitivity 67.5%, specificity 81.3%) and WHtR < 0.563 (sensitivity 81.3%, specificity 33.4%) were the best cut-offs to diagnose SAM.Conclusion: Waist circumference (< 44.5 cm for MAM; < 42.3 cm for SAM) had a reasonably good sensitivity and specificity for diagnosing MAM and SAM, but the same was not true for WHtR.","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"643-648"},"PeriodicalIF":1.7,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140848097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SpO2/FiO2 and PaO2/FiO2 for Predicting Intensive Care Admission in Wheezy Children: An Observational Study. SpO2/FiO2 和 PaO2/FiO2 预测喘息患儿重症监护入院情况：观察研究

IF 1.7 4区医学

Indian pediatrics Pub Date : 2024-07-15 Epub Date: 2024-04-22

Rakhi Beniwal, Prerna Batra, Vikram Bhaskar, Deepika Harit

{"title":"SpO2/FiO2 and PaO2/FiO2 for Predicting Intensive Care Admission in Wheezy Children: An Observational Study.","authors":"Rakhi Beniwal, Prerna Batra, Vikram Bhaskar, Deepika Harit","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To determine the sensitivity of cut-off of SpO2/FiO2 (SF ratio) < 300 at hospital admission for predicting the need for admission in the pediatric intensive care unit (PICU) in wheezy children. Secondary objectives were to determine the sensitivity of cut-off of SF ratio < 300 for predicting in-hospital mortality and that of PaO2/FiO2 (PF ratio) < 200 for predicting intensive care admission and in-hospital mortality. We also ascertained the correlation between SF ratio and PF ratio in the above population.Methods: This prospective observational study was conducted on 315 wheezy children aged 6 months to 12 years requiring admission in the pediatric emergency department. Oxygen saturation (SpO2) and fraction of oxygen in inspired air (FiO2) were recorded at admission while the partial pressure of oxygen (PaO2) was measured using arterial blood gas analysis performed within half an hour of admission. All children were managed as per protocol and followed up during hospital stay. Outcome was defined as the need for admission in the pediatric intensive care unit (PICU) or in-hospital mortality.Results: Cut -offs of SF ratio < 300 and PF ratio < 200 were able to determine the need PICU admission with a sensitivity of 97.30% and 62.16% respectively. The best cut-off of SF ratio for predicting PICU admission was < 178.79 [AUC (95% CI) 0.841 (0.767, 0.914)], while that for PF ratio was < 201.81 [AUC (95% CI) of 0.849 (0.775, 0.924)]. Cut-offs of < 300 for SF ratio and < 200 of PF ratio, were able to predict in-hospital mortality with sensitivity of 100%, but specificity of only 3.33% and 46.67%, respectively. There was only a moderate correlation between SF ratio and PF ratio (r = 0.44, P < 0.001).Conclusion: SpO2/FiO2 cut-off of < 300 had a good sensitivity in determining need for PICU admission. SF ratio has only a moderate correlation with PF ratio.","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"632-636"},"PeriodicalIF":1.7,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140852108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0