Indian pediatrics最新文献_第10页

Gestational Age Maturity: Have Our Assessment Tools Truly Matured and Come of Age? 胎龄成熟度：我们的评估工具是否真正成熟和成熟？

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-04-01 Epub Date: 2025-04-10 DOI: 10.1007/s13312-025-00044-2

Sourabh Dutta

引用次数: 0

Assessment of Cerebral Perfusion Pressure by Transcranial Doppler in Pediatric Patients with Convulsive Status Epilepticus. 经颅多普勒评价小儿惊厥性癫痫持续状态的脑灌注压。

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-04-01 Epub Date: 2025-03-12 DOI: 10.1007/s13312-025-00002-y

Aritra Kapat, Angana Bhattacharjee, Kaushani Chatterjee, Gobinda Mondal, Asok Kumar Mandal

{"title":"Assessment of Cerebral Perfusion Pressure by Transcranial Doppler in Pediatric Patients with Convulsive Status Epilepticus.","authors":"Aritra Kapat, Angana Bhattacharjee, Kaushani Chatterjee, Gobinda Mondal, Asok Kumar Mandal","doi":"10.1007/s13312-025-00002-y","DOIUrl":"10.1007/s13312-025-00002-y","url":null,"abstract":"Objective: To study the changes in cerebral hemodynamics and cerebral perfusion pressure (CPP) in children with convulsive status epilepticus (SE) by bedside transcranial doppler (TCD).Methods: Transcranial doppler of bilateral middle cerebral artery (MCA) was performed in 42 antiepileptic drug naïve convulsive SE patients (1-12 years) within 30 min of seizure termination and in 42 hemodynamically stable patients with non-neurological symptoms without any pre-existing cardiovascular and renal pathologies. The mean flow velocity (Fvm), diastolic flow velocity (Fvd) and peak systolic velocity (PSV) were measured, and CPP was calculated.Results: Mean (SD) Fvd, PSV, Fvm, and CPP in the right MCA in study group was 57.85 (3.57) cm/s, 139.90 (7.07) cm/s 85.19 (3.30) cm/s and 68.40 (4.91) mm Hg, respectively, and corresponding values in left MCA were 58.04 (3.35) cm/s, 139.90 (6.96) cm/s, 85.30 (3.20) cm/s, and 68.50 (4.93) mmHg. Alterations of Fvd, PSV, and Fvm and CPP were statistically significant in the study group compared to comparator group.Conclusion: Bedside TCD within 30 min of seizure termination in SE patients can detect alterations in cerebral flow velocities risking cerebral hypoperfusion.","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"264-268"},"PeriodicalIF":1.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Minimum Dietary Diversity and Its Determinants among Children Aged 6-60 Months in Rural Puducherry. 印度农村地区6-60月龄儿童最低膳食多样性及其决定因素

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-04-01 Epub Date: 2025-04-03 DOI: 10.1007/s13312-025-00029-1

Ilavarasu Rangassamy, Karthika Ganesamoorthy, Amarnath Santhaseelan, Premnath Dhasaram

{"title":"Minimum Dietary Diversity and Its Determinants among Children Aged 6-60 Months in Rural Puducherry.","authors":"Ilavarasu Rangassamy, Karthika Ganesamoorthy, Amarnath Santhaseelan, Premnath Dhasaram","doi":"10.1007/s13312-025-00029-1","DOIUrl":"10.1007/s13312-025-00029-1","url":null,"abstract":"Objective: To assess the prevalence of minimum dietary diversity (MDD) and explore its associated determinants among children aged 6-60 months in rural Puducherry.Methods: 143 children aged 6-60 months were selected from rural areas of Puducherry using systematic random sampling in a cross-sectional study conducted between January and February 2024. Data were collected through a semi-structured questionnaire based on World Health Organization (WHO) guidelines for Infant and Young Child Feeding (IYCF) practices. MDD was defined as the consumption of at least five of eight food groups for children aged 6-24 months and seven food groups for children aged 25-60 months. Sociodemographic factors, food group consumption, and anthropometric measurements were also recorded. Statistical analysis involved Chi-square tests and binary logistic regression to identify associations between MDD and various factors.Results: 55.24% of the children achieved MDD. Children aged 25-60 months (P < 0.001) and those with mothers over 30 years old (P = 0.001) were significantly more likely to meet MDD. Underweight (P = 0.001) and severely underweight children (P = 0.001) had a lower likelihood of achieving MDD. Factors such as gender, birth order, and socioeconomic status were not significantly associated with MDD.Conclusion: Despite a higher MDD rate than the national average, a substantial proportion of children in rural Puducherry do not meet dietary diversity standards, particularly younger (< 24 months) and underweight children.","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"283-288"},"PeriodicalIF":1.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

FGF23-Mediated Hypophosphatemic Rickets: Phenotype, Genotype, and Comparison to Non-FGF23-Mediated Forms. fgf23介导的低磷血症佝偻病：表型、基因型和与非fgf23介导形式的比较

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-03-01 Epub Date: 2025-03-07 DOI: 10.1007/s13312-025-00024-6

Manjiri Pramod Karlekar, Manjunath Havalappa Dodamani, Anurag Lila, Saba Samad Memon, Anima Sharma, Vijaya Sarathi, Samiksha Hegishte, Rohit Barnabas, Nalini Shah, Tushar Bandgar

{"title":"FGF23-Mediated Hypophosphatemic Rickets: Phenotype, Genotype, and Comparison to Non-FGF23-Mediated Forms.","authors":"Manjiri Pramod Karlekar, Manjunath Havalappa Dodamani, Anurag Lila, Saba Samad Memon, Anima Sharma, Vijaya Sarathi, Samiksha Hegishte, Rohit Barnabas, Nalini Shah, Tushar Bandgar","doi":"10.1007/s13312-025-00024-6","DOIUrl":"10.1007/s13312-025-00024-6","url":null,"abstract":"Objective: To compare the phenotypic, biochemical, and genotypic characteristics of hereditary FGF23-mediated hypophosphatemic rickets (FGF23-M-HR) and non-FGF23-mediated hypophosphatemic rickets (non-FGF23-M-HR).Methods: Clinical, biochemical, and radiological data of genetically proven FGF23-M-HR and non-FGF23-M-HR cases from a single center in western India were compared.Results: Thirteen probands (6 familial; 11 females) with FGF23-M-HR with median (IQR) age of symptom onset 2.0 (1.25, 26) years and age at diagnosis 10 (3, 30) years, were included. All, but one, presented with rickets and short stature. There were 12 (7 novel) unique PHEX mutations and one homozygous novel DMP1 mutation. FGF23-M-HR had significantly higher parathormone levels (81.9 vs. 25.1 pg/mL), lower 1,25 (OH)2 D (54.9 vs. 103 ng/mL), and lower urinary calcium/creatinine ratio (0.006 vs. 0.38). Parathormone > 65.3 pg/mL has 100% specificity for diagnosing FGF23-M-HR.Conclusion: Parathormone, urinary calcium/creatinine ratio, and 1,25 (OH)2 D levels can differentiate FGF23-M-HR from non-FGF23-M-HR.","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":"62 3","pages":"211-216"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Eosinophilic Meningitis: A Live Evidence. 嗜酸性粒细胞性脑膜炎：一个活生生的证据。

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-03-01 DOI: 10.1007/s13312-025-00017-5

Meera George, Gibi George, Vinod Jacob Cherian, Chithra Valsan

引用次数: 0

Trustworthy Evidence-Need of the Hour. 值得信赖的证据——当下的需要。

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-03-01 DOI: 10.1007/s13312-025-00022-8

Joseph L Mathew

引用次数: 0

Unlocking the Role of Biomarkers in Febrile Neutropenia. 解锁生物标志物在发热性中性粒细胞减少症中的作用。

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-03-01 DOI: 10.1007/s13312-025-00009-5

Gauri Kapoor, Payal Malhotra

引用次数: 0

Practical Concerns on Acceptability of Mobile Direct Observed Therapy (MDOT) Amongst the Parents/Caregivers of Children with Asthma. 移动直接观察治疗（MDOT）在哮喘儿童家长/照顾者中的可接受性的实际问题。

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-03-01 DOI: 10.1007/s13312-025-00020-w

Rupali Bavikar, Rajesh Kulkarni

引用次数: 0

Clinical Characteristics and Outcomes of Children with Unilateral Multicystic Dysplastic Kidney: A Cohort Study. 单侧多囊性肾发育不良儿童的临床特点和预后：一项队列研究。

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-03-01 Epub Date: 2025-03-03 DOI: 10.1007/s13312-025-00006-8

Gurram Vandana, Pediredla Karunakar, Sudarsan Krishnasamy, Ramachandran Ramge Sivakumar, Bobbity Deepthi, Bondada Hemanth Kumar, Sivamurukan Palanisamy, Ramesh Ananthakrishnan, Sriram Krishnamurthy

{"title":"Clinical Characteristics and Outcomes of Children with Unilateral Multicystic Dysplastic Kidney: A Cohort Study.","authors":"Gurram Vandana, Pediredla Karunakar, Sudarsan Krishnasamy, Ramachandran Ramge Sivakumar, Bobbity Deepthi, Bondada Hemanth Kumar, Sivamurukan Palanisamy, Ramesh Ananthakrishnan, Sriram Krishnamurthy","doi":"10.1007/s13312-025-00006-8","DOIUrl":"10.1007/s13312-025-00006-8","url":null,"abstract":"Objectives: To study the clinical profile and outcomes of children with unilateral multicystic dysplastic kidney (MCDK).Methods: We assessed the clinical features and extrarenal manifestations in children with unilateral MCDK. These children were followed up to ascertain involution, compensatory hypertrophy and progression of chronic kidney disease (CKD) stage.Results: We enrolled 106 children with unilateral MCDK which was detected antenatally in 98 (92.4%), while evaluating for urinary tract infection in three (2.8%), and incidentally in five (4.7%) children. Abnormalities in the contralateral kidney and extrarenal manifestations at initial presentation were detected in 30 (28.3%) and 15 (14.2%), respectively. At a median (IQR) follow-up of 60 (32, 87) months, 34 (32.1%) children demonstrated complete involution of the MCDK, while 72 (67.9%) showed compensatory hypertrophy in the contralateral kidney. The median age at involution of MCDK was 48.5 (33, 86.5) months. Twenty-two (20.7%) children had non-regression of MCDK, and two (1.9%) underwent nephrectomy. Eight (7.5%) children developed hypertension and two children were detected to have proteinuria. One child, each, progressed to CKD stage 2 and stage 3a; and another child (0.9%) progressed to end stage kidney disease. None of the patients developed malignant transformation.Conclusions: Majority of cases (92.4%) of MCDK had been detected antenatally. The rate of involution was 32.1% at a median follow-up of 60 months. Although, 28.3% of cases of MCDK had abnormalities in the contralateral kidney, progression of CKD to a higher stage occurred only in three (2.8%) cases.","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":"62 3","pages":"203-209"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Should Liberal Fluid Therapy (Compared to Restrictive Fluid Therapy) be used in Children with Septic Shock? No. 感染性休克患儿是否应采用自由液体疗法（与限制性液体疗法相比）？否。

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-03-01 DOI: 10.1007/s13312-025-00014-8

Madhusudan Samprathi

引用次数: 0