Indian pediatrics最新文献_第10页

Broadening the Evidence Base for IVIg in Pediatric Myocarditis: A Call for Pragmatism. 扩大IVIg治疗小儿心肌炎的证据基础：实用主义的呼吁。

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-03-01 DOI: 10.1007/s13312-025-00021-9

Surendra Bahadur Mathur, Anurag Agarwal

引用次数: 0

Is Docosahexaenoic Acid Supplementation During Pregnancy and Lactation Beneficial for the Mother-Infant Dyad? 孕期和哺乳期补充二十二碳六烯酸对母婴有益吗？

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-03-01 DOI: 10.1007/s13312-025-00010-y

Jayashree Mondkar

引用次数: 0

Unpacking the Perceptions on Take Home Rations for Under-3 Children in Telangana State: Insights from the STAR Trial. 解开泰伦加纳邦3岁以下儿童带口粮回家的观念：来自STAR试验的见解。

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-03-01 DOI: 10.1007/s13312-025-00019-3

Teena Dasi, Little Flower Augustine, Santosh Kumar Banjara, Sai Ram Challa, Ravindranadh Palika

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Clinico-etiological Profile and Metabolic Complications in Pediatric Early Onset Obesity - Experience from a Tertiary Care Centre in India. 小儿早发性肥胖的临床病因学特征和代谢并发症——来自印度三级保健中心的经验。

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-02-15 DOI: 10.1007/s13312-025-3379-1

Simran Syal, Vrushali Takalikar, Sudha Rao, Rajesh Joshi, Minnie Bodhanwala

{"title":"Clinico-etiological Profile and Metabolic Complications in Pediatric Early Onset Obesity - Experience from a Tertiary Care Centre in India.","authors":"Simran Syal, Vrushali Takalikar, Sudha Rao, Rajesh Joshi, Minnie Bodhanwala","doi":"10.1007/s13312-025-3379-1","DOIUrl":"10.1007/s13312-025-3379-1","url":null,"abstract":"Objective: To describe the clinical and metabolic profile and associated risk factors in children with early onset obesity (presenting before five years of age). To identify features that would differentiate primary from secondary obesity in under-five children.Methods: A retrospective study analyzed the medical records of children diagnosed with early onset obesity between June 2015 to December 2023 to ascertain the etiological diagnosis and identify the risk predictors. Laboratory profiles and genetic studies, wherever available, were studied. Association of various factors with underlying etiology was done using standard statistical methods.Results: Out of 530 children presenting with obesity during the study period, 77 (14.5%) were aged less than 5 years. Primary obesity was found in 55 (71.4%) children. Genetic causes of obesity were confirmed in 14 (18.18%) children. Increased screen time (more than 2 hours per day) and acanthosis nigricans correlated positively with the presence of primary obesity. Additionally, a significant association was observed between the presence of obesity in parents and early onset primary obesity, indicating a combined influence of an unhealthy lifestyle and a genetic predisposition.Conclusion: Primary obesity was more common in early onset obesity. Obesity in parents, excess screen time and presence of acanthosis nigricans were significantly associated with primary obesity suggesting a combination of genetic predisposition and unhealthy lifestyle as risk factors.","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":"62 2","pages":"138-142"},"PeriodicalIF":1.7,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143254738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevention of VAP Using Hypertonic Saline Nebulization in NICU: A Randomized Controlled Trial. NICU高渗盐水雾化预防VAP：一项随机对照试验。

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-02-15 DOI: 10.1007/s13312-025-3373-7

Arpit Gupta, Mukesh Vir Singh, Rajesh Kumar Yadav, - Monica, Anubha Shrivastava

{"title":"Prevention of VAP Using Hypertonic Saline Nebulization in NICU: A Randomized Controlled Trial.","authors":"Arpit Gupta, Mukesh Vir Singh, Rajesh Kumar Yadav, - Monica, Anubha Shrivastava","doi":"10.1007/s13312-025-3373-7","DOIUrl":"10.1007/s13312-025-3373-7","url":null,"abstract":"Objective: To evaluate the efficacy and safety of hypertonic saline (HS) nebulization in reducing the occurrence of ventilator associated pneumonia (VAP) by comparison of modified Clinical Pulmonary Infection Score (mCPIS) in HS nebulized and non-nebulized newborns.Methods: A randomized controlled study with 1:1 participant allocation ratio was conducted in a tertiary centre in North India. Neonates who received mechanical ventilation at the centre were included. Those who had been intubated for >12 hours at outside hospitals were excluded. The study group received nebulization with HS for seven days or till extubation (whichever was earlier). Both groups were compared in terms of occurrence of VAP and mCPIS. mCPIS ≥ 6 was used to suggest VAP. VAP was confirmed by a positive blood culture in ventilated newborns with clinicoinvestigative features of VAP.Results: A total of 143 neonates were analyzed in each group. VAP rate (per 1000 mechanical ventilation-days) in the HS nebulization and the control groups were 36.72 and 51.51, respectively; P = 0.031. A 33.52% reduction in the rate of VAP was observed due to HS nebulization. [RR (95% CI) 0.67 (0.47, 0.95), P = 0.022]. The mean (SD) mCPIS in HS group was 5.22 (0.88) compared to 5.94 (1.07) in the control group; P = 0.030. Only 5.5% neonates in the intervention group developed wheezing.Conclusion: Nebulization with HS reduces the incidence of VAP in ventilated newborns without significant side effects.","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":"62 2","pages":"109-115"},"PeriodicalIF":1.7,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Albumin Infusion in Children With Fluid Refractory Severe Dengue: A Comparative Study. 白蛋白输注治疗难治性重症登革热患儿的比较研究

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-02-15 DOI: 10.1007/s13312-025-3372-8

Amandeep Kaur, Siddharth Bhargava, Gurdeep Singh Dhooria, Puneet A Pooni, Deepak Bhat, Kamal Arora, Karambir S Gill, Mitali Sharma

{"title":"Albumin Infusion in Children With Fluid Refractory Severe Dengue: A Comparative Study.","authors":"Amandeep Kaur, Siddharth Bhargava, Gurdeep Singh Dhooria, Puneet A Pooni, Deepak Bhat, Kamal Arora, Karambir S Gill, Mitali Sharma","doi":"10.1007/s13312-025-3372-8","DOIUrl":"10.1007/s13312-025-3372-8","url":null,"abstract":"Objectives: To evaluate the effect of 25% albumin in addition to standard treatment (ST) in children with fluid refractory severe dengue on morbidity and mortality compared with ST alone.Methods: This was a comparative study that enrolled children aged 2 months to 18 years with severe dengue who presented to emergency between 2021-2023. Patients who were in circulatory shock after 40 mL per kg of crystalloid/colloid bolus within 1-2 hours of admission were equally categorized into two groups. ST-plus albumin group enrolled patients prospectively and received an albumin infusion (0.5-1 g/kg) in addition to ST as per WHO guidelines. ST-only group enrolled patients retrospectively who had received only ST. Demographic data, clinical course, laboratory parameters and outcomes were compared.Results: Baseline characteristics were comparable between the two groups. Survival was significantly higher in the ST-plus albumin group (97.1%) than in the ST-only group (77.1%); P = 0.043. The need for inotropic support was significantly lower in ST-plus albumin group (60%) than ST-only group (94.3%); P < 0.001. The incidence of bleeding (P = 0.008), AKI (P = 0.065), need for diuretics (P = 0.029) and renal replacement therapy (P = 0.028) were significantly lower in children in the ST-plus albumin group than ST-only group.Conclusion: The addition of 25% albumin to fluid refractory severe dengue early in the disease course led to better survival, less fluid accumulation and bleeding, and lesser incidence of complications.","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":"62 2","pages":"102-108"},"PeriodicalIF":1.7,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Post Transplant Outcomes of High-Risk Neuroblastoma From a Tertiary Care Unit in India. 高危神经母细胞瘤移植后的结果从印度三级护理单位。

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-02-15 DOI: 10.1007/s13312-025-3381-7

Shivam Bansal, Rahul Kumar, Aditya Kumar Gupta, Jagdish Prasad Meena, Rachna Seth

引用次数: 0

Gearing up for Battles Ahead 为了孩子，与同事一起，迈向更健康的国家。

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-02-15 DOI: 10.1007/s13312-025-3368-4

Vasant Khalatkar

引用次数: 0

Cerebral Blood Flow Indices During Immediate Skin-to-Skin Contact in Healthy Term Neonates: A Prospective Observational Study. 健康足月新生儿直接皮肤接触时的脑血流指数：一项前瞻性观察研究

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-02-15 DOI: 10.1007/s13312-025-3377-3

Somashekhar M Nimbalkar, Satyender S Yadav, Dipen V Patel, Mayur K Shinde, Reshma K Pujara

{"title":"Cerebral Blood Flow Indices During Immediate Skin-to-Skin Contact in Healthy Term Neonates: A Prospective Observational Study.","authors":"Somashekhar M Nimbalkar, Satyender S Yadav, Dipen V Patel, Mayur K Shinde, Reshma K Pujara","doi":"10.1007/s13312-025-3377-3","DOIUrl":"10.1007/s13312-025-3377-3","url":null,"abstract":"Objective: To evaluate the effect of skin-to-skin contact (SSC) started immediately after birth on cerebral blood flow (CBF) using middle cerebral artery (MCA) Doppler and vital parameters in stable-term infants.Methods: Clinically stable term newborns delivered through normal vaginal deliveries who only required routine care were included in this observational study through convenience sampling. Newborns with any congenital malformation or multiple gestation were excluded. Heart rate, oxygen saturation and CBF parameters of MCA [Peak systolic velocity (PSV), end diastolic velocity (EDV), mean velocity (MV), pulsatility index (PI) and resistive Index (RI)] were measured using transcranial Doppler sonography at 5, 20, 40, 60 minutes of SSC.Results: The mean (SD) gestational age was 38.4 (0.97) weeks. The mean CBF parameters of MCA Doppler viz., PSV, EDV, MV, and RI improved significantly at 60 min of SSC contact compared to baseline values except PI. Similarly, the physiological parameters viz; temperature, heart rate, and SPO2 showed significant improvement at 60 min of SSC care from baseline.Conclusion: SSC improves cerebral hemodynamics in hemodynamically stable term neonates.","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":"62 2","pages":"126-130"},"PeriodicalIF":1.7,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143254435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

One Milligram Versus Two Milligram Intramuscular Vitamin K to Prevent Late-Onset Hemorrhagic Disease in Young Infants: A Randomized Controlled Trial. 1毫克vs 2毫克肌注维生素K预防婴幼儿迟发性出血性疾病：一项随机对照试验

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-02-15 DOI: 10.1007/s13312-025-3374-6

Amala Srilatha Natarajan, C G Delhikumar, G P Senthil Kumar, Nivedita Mondal, R Sasirekha

{"title":"One Milligram Versus Two Milligram Intramuscular Vitamin K to Prevent Late-Onset Hemorrhagic Disease in Young Infants: A Randomized Controlled Trial.","authors":"Amala Srilatha Natarajan, C G Delhikumar, G P Senthil Kumar, Nivedita Mondal, R Sasirekha","doi":"10.1007/s13312-025-3374-6","DOIUrl":"10.1007/s13312-025-3374-6","url":null,"abstract":"Objective: To compare the efficacy of a standard dose (1 mg) with 2 mg vitamin K administered by intramuscular (IM) route in reducing subclinical late-onset vitamin K deficiency bleeding (VKDB) assessed using serum protein induced by vitamin K absence (PIVKA II) levels.Methods: This was an open-labeled randomized controlled trial that enrolled healthy term neonates delivered vaginally. Neonates delivered to mothers receiving antiepileptics, anti-tuberculous drugs, or warfarin, and those with a family history of bleeding disorder were excluded. Participants were randomized to receive either 1 or 2 mg of vitamin K1 (Phytomenadione) IM at birth. PIVKA II was measured in the cord blood and at 30 and 72 days after birth by ELISA method. PIVKA II level >100 ng/mL was labeled as subclinical VKDB.Results: Forty-one neonates were recruited in each arm. On the 30 days follow-up visit 9 infants (4 in 1 mg group; 5 in 2 mg group) were lost to follow-up. All babies had PIVKA II levels >100 ng/mL at birth. The median PIVKA II values (ng/mL) in the 1 mg group were 827.68 (cord blood), 678.80 (30 days), and 644.10 (72 days). The corresponding levels (ng/mL) in the 2 mg group were higher, viz., 770.55, 726.35, and 693.14 ng/mL; P > 0.05 for all comparisons. PIVKA II level in the 1 mg group reduced significantly on 72 days of life compared to that observed at birth (cord blood) (P = 0.012). However, the fall in 2 mg group was not statistically significant.Conclusion: There was no difference in PIVKA II levels between neonates receiving 1 mg or 2 mg vitamin K IM suggesting a similar risk for late-onset VKDB in both groups.","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":"62 2","pages":"116-120"},"PeriodicalIF":1.7,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0