Indian pediatricsPub Date : 2025-06-01Epub Date: 2025-04-01DOI: 10.1007/s13312-025-00040-6
Shalabh Garg, Adnan Zafar
{"title":"Non-Invasive Blood Pressure Measurement in Extremely Preterm Neonates: Comparative Analysis of Different Methods.","authors":"Shalabh Garg, Adnan Zafar","doi":"10.1007/s13312-025-00040-6","DOIUrl":"10.1007/s13312-025-00040-6","url":null,"abstract":"<p><strong>Objectives: </strong>To compare non-invasive (Doppler and Oscillometric) and invasive (indwelling umbilical arterial catheter, UAC) methods for measuring blood pressure in extremely preterm neonates.</p><p><strong>Methods: </strong>Neonates < 28 weeks gestation were recruited if UAC was inserted as part of their clinical care. Blood pressure measured 4-6 hourly by Oscillometric and Doppler methods was compared with invasive method (10-15 readings/baby).</p><p><strong>Results: </strong>438 blood pressure recordings were taken from 11 neonates. Compared to invasive method, non-invasive methods underestimated (P = 0.630) and overestimated (P = 0.431 for > 10% overestimation, P = 0.960 for > 20% overestimation) blood pressure. The frequency of blood pressure being within 10% of UAC reading was higher with the Oscillometric method compared to Doppler (41% vs 17%).</p><p><strong>Conclusions: </strong>Compared to invasive arterial recording, non-invasive methods underestimated as well as overestimated blood pressure in extremely preterm neonates. Oscillometric methods are more reliable compared to Doppler methods.</p>","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"433-436"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Indian pediatricsPub Date : 2025-06-01Epub Date: 2025-04-02DOI: 10.1007/s13312-025-00039-z
Kumar Guru Mishra, Nabnita Patnaik, Nihar Ranjan Pradhan
{"title":"School Teachers' Perspectives on National Iron Plus Initiative Implementation: A Qualitative Study.","authors":"Kumar Guru Mishra, Nabnita Patnaik, Nihar Ranjan Pradhan","doi":"10.1007/s13312-025-00039-z","DOIUrl":"10.1007/s13312-025-00039-z","url":null,"abstract":"<p><strong>Objective: </strong>To explore the school teachers' perspectives on factors affecting the implementation of National Iron Plus Initiative (NIPI).</p><p><strong>Methods: </strong>A qualitative participatory study was conducted in six schools in rural areas of Telangana, involving free listing, pile sorting, and force field analysis. Analysis included frequency calculations, multidimensional scaling, hierarchical cluster analysis, and thematic analysis.</p><p><strong>Results: </strong>Fifty four teachers participated; 25 barriers and 14 enablers were identified. Key barriers included lack of education and health literacy, negative attitudes, lack of faith in public services, and unhygienic practices. Major enablers were school-based anemia-related activities, government awareness programs, and programmatic interventions. Force field analysis revealed attitudes and awareness gaps as significant barriers, while school-based activities emerged as the primary enabler.</p><p><strong>Conclusion: </strong>School-based interventions, addressing attitudinal and educational barriers, and adopting a holistic approach are crucial for effective anemia prevention in rural settings.</p>","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"421-427"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143763455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intramuscular Versus Oral Ondansetron for Management of Children with Acute Dehydrating Diarrhea and Vomiting: A Randomized Controlled Trial.","authors":"Shubham Satyesh, Rajesh Kumar Meena, Dheeraj Shah, Rumpa Saha, Piyush Gupta","doi":"10.1007/s13312-025-00049-x","DOIUrl":"10.1007/s13312-025-00049-x","url":null,"abstract":"<p><strong>Objectives: </strong>To compare efficacy and safety of intramuscular (IM) ondansetron with oral ondansetron for improving utilization of Oral Rehydration Therapy (ORT) by controlling vomiting in children with acute diarrhea and some dehydration.</p><p><strong>Methods: </strong>We enrolled children aged 3 months to 12 years presenting with acute diarrhea (duration < 14 days) with some dehydration, and at least two episodes of vomiting within last 6 h in an open-label randomized controlled trial. Participants were randomized to receive single dose (0.2 mg/kg) of IM or oral ondansetron before starting ORT. Primary outcome was failure of ORT (persistence of some dehydration after 4 h of ORT or need for intravenous fluids). Secondary outcomes included need for unscheduled intravenous fluids, amount of Oral Rehydration Salt Solution (ORS) ingested after 4 h, frequency of vomiting episodes, adverse effects, and caregiver satisfaction.</p><p><strong>Results: </strong>We randomized 60 children (31 IM, 29 oral); 58 (29 per group) were followed-up for all outcomes. There were no significant differences between IM and oral routes in terms of ORT failure (31% vs. 24.1%; RR (95% CI) 1.3 (0.5, 3.0), P = 0.557), need for IV fluids during ORT (24.1% vs. 20.7%; P = 0.753), mean (SD) ORS ingested (mL) in 4 h [616.2 (429.7) vs. 645.5 (403.5); P = 0.79], mean (SD) frequency of vomiting [1.4 (2.0) vs. 2.3 (2.4); P = 0.107] or caregiver satisfaction. No adverse events attributable to the intervention were observed.</p><p><strong>Conclusion: </strong>Intramuscular ondansetron may not offer any advantage over oral use in management of children with acute diarrhea with vomiting and some dehydration.</p><p><strong>Trial registration: </strong>Clinical Trials Registry-India (CTRI/2020/01/023082) available at ctri.nic.in.</p>","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"414-420"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143763389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Indian pediatricsPub Date : 2025-06-01Epub Date: 2025-04-02DOI: 10.1007/s13312-025-00027-3
Nimisha S Dange, Vaman Khadilkar, Ketan Gondhalekar, Anuradha V Khadilkar
{"title":"Double Burden of Malnutrition in Under-Five Children (NFHS-5 Data) Using Extended CIAF: WHO 2006 Growth Standard Versus 2019 Indian Growth References.","authors":"Nimisha S Dange, Vaman Khadilkar, Ketan Gondhalekar, Anuradha V Khadilkar","doi":"10.1007/s13312-025-00027-3","DOIUrl":"10.1007/s13312-025-00027-3","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the double burden of malnutrition (DBM) in under-five children using extended composite index of anthropometric failure (eCIAF) using WHO 2006 and 2019 Indian standards.</p><p><strong>Methods: </strong>Data of 2,32,920 under-five children as per National Family Health Survey-5 were eligible for inclusion. Incomplete records and extreme z-scores were excluded. eCIAF categories included: A No failure; B Wasted; C Wasted + Underweight; D Wasted + Stunted + Underweight; E Stunted + Underweight; F Stunted; G Stunted + Overweight; H Overweight; Y Underweight; Underfailure (UF): A + B + C + D + E + F + Y; Overfailure (OF): G + H.</p><p><strong>Results: </strong>Records of 1,96,015 under-five children were analyzed. 50.1% versus 74% children were categorized as no failure using WHO and Indian standards, respectively (P < 0.001). Prevalence of DBM, UF and OF using WHO reference was significantly higher than using Indian references [49.9% vs. 26%; 48.4% vs. 24.7%; 3.5% vs. 1.9%, respectively].</p><p><strong>Conclusion: </strong>Using Indian references prevents misclassification of DBM in under-fives.</p>","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"428-432"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143763385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Indian pediatricsPub Date : 2025-06-01Epub Date: 2025-04-29DOI: 10.1007/s13312-025-00077-7
Jogender Kumar, Praveen Kumar, Vineet Bhandari
{"title":"Noninvasive Ventilation Strategies in Neonates.","authors":"Jogender Kumar, Praveen Kumar, Vineet Bhandari","doi":"10.1007/s13312-025-00077-7","DOIUrl":"10.1007/s13312-025-00077-7","url":null,"abstract":"<p><p>We provide recommendations on neonatal noninvasive ventilation (NIV) strategies used in the delivery room (DR) and neonatal intensive care unit (NICU). A systematic search was performed in the PubMed, Embase, and CENTRAL databases to identify relevant literature from the past 5 years. A critical review of the available literature was conducted to provide context-specific recommendations. In the DR, we recommend using nasal continuous positive airway pressure (NCPAP) or nasal intermittent positive pressure ventilation (NIPPV) with a T-piece resuscitator (TPR). Surfactant replacement therapy should be administered early (< 2 h of life) in infants requiring NCPAP of 6-7 cm H<sub>2</sub>O and FiO<sub>2</sub> > 0.3, using less invasive surfactant administration techniques. Infants should be transported to the NICU on positive pressure support using NCPAP or TPR. In extremely preterm infants with severe respiratory distress requiring intubation in the DR, surfactant should be considered during the intubation. If equipment and expertise are available in the NICU, NIPPV is the preferred mode of NIV. Nasal masks or short binasal prongs are the preferred nasal interfaces. A heated, humidified, high flow nasal cannula is not recommended as the primary mode of NIV. Additional clinical trials are needed for nasal high frequency ventilation and noninvasive ventilation neurally adjusted ventilatory assist modes of NIV. Guidelines for the recommended initial and maximal settings for primary, post-extubation, and weaning off NIV in neonates are provided in this article. NIPPV and NCPAP are the preferred modes of NIV in neonates with respiratory distress.</p>","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"451-460"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12106148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of Clinical Risk Index for Babies (CRIB) II Score and Extended Sick Neonatal Score (ESNS) as a Predictor of In-hospital Mortality in Premature Neonates with Gestational Age ≤ 32 Weeks.","authors":"Goolla Akhila, Jasashree Choudhury, Vijay Kumar Krishnegowda, Debasish Nanda","doi":"10.1007/s13312-025-00107-4","DOIUrl":"https://doi.org/10.1007/s13312-025-00107-4","url":null,"abstract":"<p><strong>Objective: </strong>To compare Clinical Risk Index for Babies (CRIB) II score and Extended Sick Neonatal Score (ESNS) for predicting in-hospital mortality in premature neonates with gestational age ≤ 32 weeks.</p><p><strong>Method: </strong>This prospective observational study included 110 preterm neonates less than equal to 32 weeks of gestation. Clinical parameters of CRIB II score and ESNS were documented at time of admission and laboratory parameter were obtained with 24 h. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and likelihood ratio of the two scores as a predictor of mortality were compared.</p><p><strong>Result: </strong>The sensitivity, specificity, PPV, NPV and the Area under the Receiver Operating Characteristic (ROC) curve of CRIB II score at a cut-off value of ≥ 10 were 85.2%, 96.4%, 88.5%, 95.2%, ands 0.91 (95%CI 0.83, 0.98) respectively. The corresponding values for ESNS at a cut-off value of ≤ 11, were 77.8%, 71.1%, 46.7%, 90.8% and 0.85 (95%CI 0.78, 0.92) respectively. CRIB II score had better predictive accuracy for in-hospital mortality among premature neonates compared to ESNS (0.93 v 0.73).</p><p><strong>Conclusion: </strong>Both CRIB II and ESNS are useful tools to predict the risk of mortality during hospital stay in premature neonates. However, CRIB II score has a better predictive ability for in-hospital mortality in comparison with ESNS.</p>","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144158255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of Vitamin B12, Folate, and Iron Deficiency in Adolescents in the Yadadri-Bhuvanagiri District of Telangana: a Community-based Study.","authors":"Emine A Rahiman, Gomathi Ramaswamy, Rajendra Prasad Anne, Sangeetha Sampath, Patil Parag Parshuram","doi":"10.1007/s13312-025-00096-4","DOIUrl":"https://doi.org/10.1007/s13312-025-00096-4","url":null,"abstract":"<p><strong>Objectives: </strong>To determine the prevalence of anemia and iron, folate, and vitamin B12 deficiency in the adolescents of Yadadri-Bhuvanagiri district of Telangana.</p><p><strong>Methods: </strong>A cross-sectional community-based study was conducted. Prevalence of anemia and micronutrient deficiencies were calculated and analyzed for age, sex, socio-economic status, diet, menstruation, and growth.</p><p><strong>Results: </strong>The prevalence of anemia and deficiency of iron, vitamin B12 and folate was 34.1%, 29.2%, 77.4%, and 8.7%. Anemia and iron deficiency were higher in girls compared to boys (41.2% vs 20.9%,, P < 0.001; 39.5% vs 9.8%, P < 0.001) and girls in active menstruation (44.6% vs 12.1%; 42.3% vs 21.2%, P < 0.001). Anemia was more in older girls (15-19 years) compared to those aged 10-14 years (50% vs 28.9%; P < 0.001).</p><p><strong>Conclusions: </strong>Anemia is a significant health problem for older girls. Vitamin B12 deficiency is prevalent in nearly three-fourths of adolescents.</p>","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}