Comparison of Clinical Risk Index for Babies (CRIB) II Score and Extended Sick Neonatal Score (ESNS) as a Predictor of In-hospital Mortality in Premature Neonates with Gestational Age ≤ 32 Weeks.

IF 1.7 4区医学 Q2 PEDIATRICS

Indian pediatrics Pub Date : 2025-05-28 DOI:10.1007/s13312-025-00107-4

Goolla Akhila, Jasashree Choudhury, Vijay Kumar Krishnegowda, Debasish Nanda

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引用次数: 0

Abstract

Objective: To compare Clinical Risk Index for Babies (CRIB) II score and Extended Sick Neonatal Score (ESNS) for predicting in-hospital mortality in premature neonates with gestational age ≤ 32 weeks.

Method: This prospective observational study included 110 preterm neonates less than equal to 32 weeks of gestation. Clinical parameters of CRIB II score and ESNS were documented at time of admission and laboratory parameter were obtained with 24 h. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and likelihood ratio of the two scores as a predictor of mortality were compared.

Result: The sensitivity, specificity, PPV, NPV and the Area under the Receiver Operating Characteristic (ROC) curve of CRIB II score at a cut-off value of ≥ 10 were 85.2%, 96.4%, 88.5%, 95.2%, ands 0.91 (95%CI 0.83, 0.98) respectively. The corresponding values for ESNS at a cut-off value of ≤ 11, were 77.8%, 71.1%, 46.7%, 90.8% and 0.85 (95%CI 0.78, 0.92) respectively. CRIB II score had better predictive accuracy for in-hospital mortality among premature neonates compared to ESNS (0.93 v 0.73).

Conclusion: Both CRIB II and ESNS are useful tools to predict the risk of mortality during hospital stay in premature neonates. However, CRIB II score has a better predictive ability for in-hospital mortality in comparison with ESNS.

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婴儿临床风险指数（CRIB） II评分与延长新生儿疾病评分（ESNS）作为胎龄≤32周早产儿住院死亡率预测因子的比较

目的：比较婴儿临床风险指数（CRIB） II评分与延长新生儿疾病评分（ESNS）对胎龄≤32周早产儿住院死亡率的预测价值。方法：本前瞻性观察研究纳入110例妊娠小于32周的早产儿。入院时记录CRIB II评分和ESNS的临床参数，24 h后获取实验室参数。比较两种评分作为死亡率预测指标的敏感性、特异性、阳性预测值（PPV）、阴性预测值（NPV）和似然比。结果：CRIB II评分在截断值≥10时的敏感性为85.2%，特异性为96.4%，PPV为88.5%，NPV为95.2%，ROC曲线下面积为0.91 （95%CI 0.83, 0.98）。ESNS在临界值≤11时的对应值分别为77.8%、71.1%、46.7%、90.8%和0.85 （95%CI 0.78、0.92）。与ESNS相比，CRIB II评分对早产儿住院死亡率的预测准确性更高（0.93 vs 0.73）。结论：CRIB II和ESNS是预测早产儿住院期间死亡风险的有效工具。然而，与ESNS相比，CRIB II评分对院内死亡率有更好的预测能力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Indian pediatrics 医学-小儿科

CiteScore

3.30

自引率

8.70%

发文量

344

审稿时长

3-8 weeks

期刊介绍： The general objective of Indian Pediatrics is "To promote the science and practice of Pediatrics." An important guiding principle has been the simultaneous need to inform, educate and entertain the target audience. The specific key objectives are: -To publish original, relevant, well researched peer reviewed articles on issues related to child health. -To provide continuing education to support informed clinical decisions and research. -To foster responsible and balanced debate on controversial issues that affect child health, including non-clinical areas such as medical education, ethics, law, environment and economics. -To achieve the highest level of ethical medical journalism and to produce a publication that is timely, credible and enjoyable to read.