Indian pediatrics最新文献_第3页

Diagnostic Performance of Mean Neutrophil Volume in Neonatal Sepsis. 平均中性粒细胞体积在新生儿脓毒症中的诊断价值。

IF 1.5 4区医学

Indian pediatrics Pub Date : 2025-10-01 Epub Date: 2025-07-28 DOI: 10.1007/s13312-025-00144-z

Santosh Kumar Panda, T Jenith, Nageswar Sahu, Palash Das, Sourav Padhee

引用次数: 0

Skin Damage Risk and its Severity Caused by Pulse Oximetery Saturation Probe Attachment in Preterm Neonates: A Prospective Observational Study from Western India. 脉搏血氧饱和度探头附着引起的早产儿皮肤损伤风险及其严重程度：一项来自印度西部的前瞻性观察研究。

IF 1.5 4区医学

Indian pediatrics Pub Date : 2025-10-01 Epub Date: 2025-05-26 DOI: 10.1007/s13312-025-00100-x

Aditya Hemendra Bhatt, Dipen Vasudev Patel, Reshma Kushal Pujara, Mayur Kiran Shinde, Somashekhar Marutirao Nimbalkar

引用次数: 0

Disease and economic burden of stillbirths in India in 2019. 2019年印度死产的疾病和经济负担。

IF 1.5 4区医学

Indian pediatrics Pub Date : 2025-09-30 DOI: 10.1007/s13312-025-00196-1

Vidhi Wadhwani, Divya Shrinivas, Sweta Dubey, Siddhesh Zadey

{"title":"Disease and economic burden of stillbirths in India in 2019.","authors":"Vidhi Wadhwani, Divya Shrinivas, Sweta Dubey, Siddhesh Zadey","doi":"10.1007/s13312-025-00196-1","DOIUrl":"https://doi.org/10.1007/s13312-025-00196-1","url":null,"abstract":"Objective: India has the highest number of stillbirths worldwide. However, the disease and economic burdens of stillbirths in India remain missing. This study aimed to estimate the disease and economic burden associated with stillbirths in India and its states for 2019.Methods: A retrospective analysis was conducted using stillbirth data from the health management information system (HMIS) and civil and sample registration systems (CRS and SRS) for India and its states. Disease burden was calculated as disability-adjusted life years (DALYs) and economic burden as value of life years (VLYs). A sensitivity analysis for disease burden estimation was performed using a framework that estimated DALYs using a stillbirth-adjusted life expectancy.Results: Indian HMIS reported 263,342 stillbirths in 2019. Nationally, stillbirths led to 18.3 million DALYs and a monetary loss of INR 7.80 trillion. Uttar Pradesh, Maharashtra, Rajasthan, Madhya Pradesh, Gujarat, and West Bengal contributed to more than 40% of the burden. The sensitivity analysis showed consistent findings.Conclusion: Stillbirths should be prioritized in the public health agenda as they contribute to a high burden of disease and disability.","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hereditary Tyrosinemia Type 1: Success and Challenges in Indian Subcontinent. 遗传性酪氨酸血症1型：印度次大陆的成功与挑战。

IF 1.5 4区医学

Indian pediatrics Pub Date : 2025-09-26 DOI: 10.1007/s13312-025-00182-7

Samannay Das, Vikrant Sood, Bikrant Bihari Lal, Rajeev Khanna, Seema Alam, Chhagan Bihari

{"title":"Hereditary Tyrosinemia Type 1: Success and Challenges in Indian Subcontinent.","authors":"Samannay Das, Vikrant Sood, Bikrant Bihari Lal, Rajeev Khanna, Seema Alam, Chhagan Bihari","doi":"10.1007/s13312-025-00182-7","DOIUrl":"https://doi.org/10.1007/s13312-025-00182-7","url":null,"abstract":"Objectives: To analyze the profile and outcomes of Indian children with hereditary tyrosinemia type 1 (HT-1).Methods: In this retrospective study, the data of children with a confirmed diagnosis of HT-1 from 2013 to 2024 admitted in the pediatric hepatology unit of a tertiary care referral center were analyzed.Results: Eighteen children with HT-1 with a median (Q1, Q3) age of diagnosis of 15.5 (6, 44) months were included. All children had established cirrhosis. Hepatocellular carcinoma (HCC) was noted in 4 patients at baseline, while HCC developed in 4 children on follow-up. Only 7 (38.9%) children could be initiated on nitisinone or 2-[2-nitro-4-trifluoromethylbenzoyl]-1,3-cyclohexanedione (NTBC). In the NTBC group (n = 7), one child survived with native liver, 3 children underwent liver transplant (LT) and 3 died. In the non-NTBC group (n = 11), 4 underwent LT (rest died). Post-LT survival was 100% without new-onset/recurrent HCC.Conclusion: Native liver outcomes for HT-1 in the Indian subcontinent remain dismal with a high proportion developing HCC and requiring LT for optimum outcomes.","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145148691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Macrolide Resistance and Mycoplasma pneumoniae DNA Load in Bronchoalveolar Lavage Fluid on Immune and Inflammatory Responses in Children with Mycoplasma pneumoniae Pneumonia. 支气管肺泡灌洗液大环内酯耐药及肺炎支原体DNA负荷对肺炎支原体肺炎患儿免疫和炎症反应的影响

IF 1.5 4区医学

Indian pediatrics Pub Date : 2025-09-24 DOI: 10.1007/s13312-025-00190-7

Haiqin Zhong, Zeyu Zeng, Haoxiang Gu, Xiaoyan Dong

{"title":"Effect of Macrolide Resistance and Mycoplasma pneumoniae DNA Load in Bronchoalveolar Lavage Fluid on Immune and Inflammatory Responses in Children with Mycoplasma pneumoniae Pneumonia.","authors":"Haiqin Zhong, Zeyu Zeng, Haoxiang Gu, Xiaoyan Dong","doi":"10.1007/s13312-025-00190-7","DOIUrl":"https://doi.org/10.1007/s13312-025-00190-7","url":null,"abstract":"Objective: To investigate the impact of macrolide resistance and Mycoplasma pneumoniae DNA (MP-DNA) load in bronchoalveolar lavage fluid (BALF) on immune and inflammatory responses in children with Mycoplasma pneumoniae pneumonia (MPP).Methods: This retrospective study included 190 hospitalized children with MPP who underwent bronchoscopy. Patients were classified as macrolide-resistant or macrolide-sensitive based on 23S rRNA mutation analysis. MP-DNA load and cytokines in BALF and inflammatory markers in blood were measured. MRMP patients were further stratified by MP-DNA load for subgroup analysis.Results: Of 1029 children screened, 474 had MPP, and 190 who underwent bronchoscopy were analyzed. Macrolide-resistant mycoplasma pneumonia (MRMP) accounted for 73.2% of cases and was associated with longer fever duration and hospital stay, lower lymphocyte counts, higher BALF total cell counts and neutrophil proportions, and increased inflammatory cytokines. Among MRMP patients, those with high MP-DNA loads had greater BALF cytokine levels than those with low loads. MP-DNA load positively correlated with IL‑1β and IL‑6 levels.Conclusions: Macrolide resistance and high pathogen load are associated with enhanced airway inflammation and immune dysregulation in children with MPP. Early detection of resistance and quantification of pathogen load may guide timely antibiotic adjustment and improve clinical outcomes.","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145130740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Silent Bowel Damage From Magnetic Ball Ingestion: A Pediatric Case Series. 磁性球摄入引起的无症状性肠损伤：一个儿科病例系列。

IF 1.5 4区医学

Indian pediatrics Pub Date : 2025-09-22 DOI: 10.1007/s13312-025-00193-4

K R Aparna, M G Joy, Robin Thomas, Neena Baby

引用次数: 0

Intrapartum Antibiotics and Neonatal Sepsis: Confounding by Indication. 产时抗生素与新生儿败血症：指征混淆。

IF 1.5 4区医学

Indian pediatrics Pub Date : 2025-09-22 DOI: 10.1007/s13312-025-00195-2

Deepak Chawla

引用次数: 0

Adenoid Hypertrophy: A Rare Cause of Hemoptysis. 腺样体肥大：一种罕见的咯血原因。

IF 1.5 4区医学

Indian pediatrics Pub Date : 2025-09-22 DOI: 10.1007/s13312-025-00198-z

Neeraj Sharma, Robin Chaudhary, Puneet Saxena

引用次数: 0

Rickets: Diagnostic Challenges and Insights. 佝偻病：诊断挑战和见解。

IF 1.5 4区医学

Indian pediatrics Pub Date : 2025-09-17 DOI: 10.1007/s13312-025-00176-5

Ankita G Sharma, Preeti Singh

引用次数: 0

Impact of Biologic Therapy, School Success, Parent's Education and Socioeconomic Status on Transition Readiness in Adolescents with Juvenile Idiopathic Arthritis and Their Parents. 生物治疗、学校成功、父母教育和社会经济地位对青少年特发性关节炎及其父母的过渡准备的影响。

IF 1.5 4区医学

Indian pediatrics Pub Date : 2025-09-15 DOI: 10.1007/s13312-025-00188-1

Dragana Lazarević, Hristina Stamenković, Tatjana Stanković, Stefan Đorđević, Dušica Novaković, Maja Zečević, Gordana Sušić, Valentina Živković

{"title":"Impact of Biologic Therapy, School Success, Parent's Education and Socioeconomic Status on Transition Readiness in Adolescents with Juvenile Idiopathic Arthritis and Their Parents.","authors":"Dragana Lazarević, Hristina Stamenković, Tatjana Stanković, Stefan Đorđević, Dušica Novaković, Maja Zečević, Gordana Sušić, Valentina Živković","doi":"10.1007/s13312-025-00188-1","DOIUrl":"https://doi.org/10.1007/s13312-025-00188-1","url":null,"abstract":"Objective: To evaluate the effect of biologic therapy, school success, parental education and socioeconomic status on transition readiness of adolescent patients with juvenile idiopathic arthritis (JIA) and their parents.Methods: This cross-sectional study enrolled adolescent patients with JIA from two pediatric clinics. Juvenile Arthritis Disease Activity Score was calculated, and Transition Readiness Assessment Questionnaire (TRAQ) was administered to the patients and their parents. Demographic and clinical data were collected.Results: The study included 91 JIA patients (median age 15.32 years, range 11.58-18 years) and their parents; 36 had active disease. Biologic usage was significantly associated with transition readiness of children (P = 0.038) and their parents (P = 0.035). School success was associated with higher levels of transition readiness; TRAQ was significantly lower in observed groups with \"good\" school success compared to \"very good\" (P = 0.024; P = 0.002) and \"excellent\" (P = 0.010; P = 0.012). Parents' education or socioeconomic status has no influence on transition readiness.Conclusion: Biologic usage and better school performance have a positive impact on the patients and their parents' transition readiness.","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145064309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0