Indian pediatrics最新文献_第3页

Intramuscular Versus Oral Ondansetron for Management of Children with Acute Dehydrating Diarrhea and Vomiting: A Randomized Controlled Trial. 肌注与口服昂丹司琼治疗儿童急性脱水腹泻和呕吐：一项随机对照试验。

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-04-02 DOI: 10.1007/s13312-025-00049-x

Shubham Satyesh, Rajesh Kumar Meena, Dheeraj Shah, Rumpa Saha, Piyush Gupta

{"title":"Intramuscular Versus Oral Ondansetron for Management of Children with Acute Dehydrating Diarrhea and Vomiting: A Randomized Controlled Trial.","authors":"Shubham Satyesh, Rajesh Kumar Meena, Dheeraj Shah, Rumpa Saha, Piyush Gupta","doi":"10.1007/s13312-025-00049-x","DOIUrl":"https://doi.org/10.1007/s13312-025-00049-x","url":null,"abstract":"Objectives: To compare efficacy and safety of intramuscular (IM) ondansetron with oral ondansetron for improving utilization of Oral Rehydration Therapy (ORT) by controlling vomiting in children with acute diarrhea and some dehydration.Methods: We enrolled children aged 3 months to 12 years presenting with acute diarrhea (duration < 14 days) with some dehydration, and at least two episodes of vomiting within last 6 h in an open-label randomized controlled trial. Participants were randomized to receive single dose (0.2 mg/kg) of IM or oral ondansetron before starting ORT. Primary outcome was failure of ORT (persistence of some dehydration after 4 h of ORT or need for intravenous fluids). Secondary outcomes included need for unscheduled intravenous fluids, amount of Oral Rehydration Salt Solution (ORS) ingested after 4 h, frequency of vomiting episodes, adverse effects, and caregiver satisfaction.Results: We randomized 60 children (31 IM, 29 oral); 58 (29 per group) were followed-up for all outcomes. There were no significant differences between IM and oral routes in terms of ORT failure (31% vs. 24.1%; RR (95% CI) 1.3 (0.5, 3.0), P = 0.557), need for IV fluids during ORT (24.1% vs. 20.7%; P = 0.753), mean (SD) ORS ingested (mL) in 4 h [616.2 (429.7) vs. 645.5 (403.5); P = 0.79], mean (SD) frequency of vomiting [1.4 (2.0) vs. 2.3 (2.4); P = 0.107] or caregiver satisfaction. No adverse events attributable to the intervention were observed.Conclusion: Intramuscular ondansetron may not offer any advantage over oral use in management of children with acute diarrhea with vomiting and some dehydration.Trial registration: Clinical Trials Registry-India (CTRI/2020/01/023082) available at ctri.nic.in.","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143763389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Double Burden of Malnutrition in Under-Five Children (NFHS-5 Data) Using Extended CIAF: WHO 2006 Growth Standard Versus 2019 Indian Growth References. 使用扩展CIAF的五岁以下儿童营养不良的双重负担（NFHS-5数据）：世卫组织2006年增长标准与2019年印度增长参考。

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-04-02 DOI: 10.1007/s13312-025-00027-3

Nimisha S Dange, Vaman Khadilkar, Ketan Gondhalekar, Anuradha V Khadilkar

{"title":"Double Burden of Malnutrition in Under-Five Children (NFHS-5 Data) Using Extended CIAF: WHO 2006 Growth Standard Versus 2019 Indian Growth References.","authors":"Nimisha S Dange, Vaman Khadilkar, Ketan Gondhalekar, Anuradha V Khadilkar","doi":"10.1007/s13312-025-00027-3","DOIUrl":"https://doi.org/10.1007/s13312-025-00027-3","url":null,"abstract":"Objectives: To compare the double burden of malnutrition (DBM) in under-five children using extended composite index of anthropometric failure (eCIAF) using WHO 2006 and 2019 Indian standards.Methods: Data of 2,32,920 under-five children as per National Family Health Survey-5 were eligible for inclusion. Incomplete records and extreme z-scores were excluded. eCIAF categories included: A No failure; B Wasted; C Wasted + Underweight; D Wasted + Stunted + Underweight; E Stunted + Underweight; F Stunted; G Stunted + Overweight; H Overweight; Y Underweight; Underfailure (UF): A + B + C + D + E + F + Y; Overfailure (OF): G + H.Results: Records of 1,96,015 under-five children were analyzed. 50.1% versus 74% children were categorized as no failure using WHO and Indian standards, respectively (P < 0.001). Prevalence of DBM, UF and OF using WHO reference was significantly higher than using Indian references [49.9% vs. 26%; 48.4% vs. 24.7%; 3.5% vs. 1.9%, respectively].Conclusion: Using Indian references prevents misclassification of DBM in under-fives.","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143763385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Erratum: Transcranial Doppler: The Bedside Window to Explore Cerebral Hemodynamics. 勘误：经颅多普勒：探索脑血流动力学的床边窗口。

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-04-01 DOI: 10.1007/s13312-025-00074-w

Muthu Chidambaram

引用次数: 0

Feasibility of Implementing Resuscitation Training for Parents of at-Risk Infants at Discharge: Author's Reply. 对高危婴儿出院时父母实施复苏培训的可行性：作者回复。

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-04-01 DOI: 10.1007/s13312-025-00046-0

A Nalina, A Shashidhar

引用次数: 0

Non-Invasive Blood Pressure Measurement in Extremely Preterm Neonates: Comparative Analysis of Different Methods. 极早产新生儿的无创血压测量：不同方法的比较分析。

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-04-01 DOI: 10.1007/s13312-025-00040-6

Shalabh Garg, Adnan Zafar

{"title":"Non-Invasive Blood Pressure Measurement in Extremely Preterm Neonates: Comparative Analysis of Different Methods.","authors":"Shalabh Garg, Adnan Zafar","doi":"10.1007/s13312-025-00040-6","DOIUrl":"https://doi.org/10.1007/s13312-025-00040-6","url":null,"abstract":"Objectives: To compare non-invasive (Doppler and Oscillometric) and invasive (indwelling umbilical arterial catheter, UAC) methods for measuring blood pressure in extremely preterm neonates.Methods: Neonates < 28 weeks gestation were recruited if UAC was inserted as part of their clinical care. Blood pressure measured 4-6 hourly by Oscillometric and Doppler methods was compared with invasive method (10-15 readings/baby).Results: 438 blood pressure recordings were taken from 11 neonates. Compared to invasive method, non-invasive methods underestimated (P = 0.630) and overestimated (P = 0.431 for > 10% overestimation, P = 0.960 for > 20% overestimation) blood pressure. The frequency of blood pressure being within 10% of UAC reading was higher with the Oscillometric method compared to Doppler (41% vs 17%).Conclusions: Compared to invasive arterial recording, non-invasive methods underestimated as well as overestimated blood pressure in extremely preterm neonates. Oscillometric methods are more reliable compared to Doppler methods.","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chemotherapy-Induced Oral Mucositis: Can We Nip it in the Bud? 化疗引起的口腔黏膜炎：我们能把它扼杀在萌芽状态吗？

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-04-01 DOI: 10.1007/s13312-025-00073-x

Neha Rastogi

引用次数: 0

Mixed Type Atypical Rabies Encephalitis: A Case Report. 混合型非典型狂犬病脑炎1例报告。

IF 1.7 4区医学

Indian pediatrics Pub Date : 2025-03-31 DOI: 10.1007/s13312-025-00043-3

Lukshay Bansal, Shibani Mehra

引用次数: 0

Breaking the Chains of Childhood Obesity. 打破儿童肥胖的枷锁。