Indian pediatricsPub Date : 2025-06-01Epub Date: 2025-04-02DOI: 10.1007/s13312-025-00027-3
Nimisha S Dange, Vaman Khadilkar, Ketan Gondhalekar, Anuradha V Khadilkar
{"title":"Double Burden of Malnutrition in Under-Five Children (NFHS-5 Data) Using Extended CIAF: WHO 2006 Growth Standard Versus 2019 Indian Growth References.","authors":"Nimisha S Dange, Vaman Khadilkar, Ketan Gondhalekar, Anuradha V Khadilkar","doi":"10.1007/s13312-025-00027-3","DOIUrl":"10.1007/s13312-025-00027-3","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the double burden of malnutrition (DBM) in under-five children using extended composite index of anthropometric failure (eCIAF) using WHO 2006 and 2019 Indian standards.</p><p><strong>Methods: </strong>Data of 2,32,920 under-five children as per National Family Health Survey-5 were eligible for inclusion. Incomplete records and extreme z-scores were excluded. eCIAF categories included: A No failure; B Wasted; C Wasted + Underweight; D Wasted + Stunted + Underweight; E Stunted + Underweight; F Stunted; G Stunted + Overweight; H Overweight; Y Underweight; Underfailure (UF): A + B + C + D + E + F + Y; Overfailure (OF): G + H.</p><p><strong>Results: </strong>Records of 1,96,015 under-five children were analyzed. 50.1% versus 74% children were categorized as no failure using WHO and Indian standards, respectively (P < 0.001). Prevalence of DBM, UF and OF using WHO reference was significantly higher than using Indian references [49.9% vs. 26%; 48.4% vs. 24.7%; 3.5% vs. 1.9%, respectively].</p><p><strong>Conclusion: </strong>Using Indian references prevents misclassification of DBM in under-fives.</p>","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"428-432"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143763385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Indian pediatricsPub Date : 2025-06-01Epub Date: 2025-04-29DOI: 10.1007/s13312-025-00077-7
Jogender Kumar, Praveen Kumar, Vineet Bhandari
{"title":"Noninvasive Ventilation Strategies in Neonates.","authors":"Jogender Kumar, Praveen Kumar, Vineet Bhandari","doi":"10.1007/s13312-025-00077-7","DOIUrl":"10.1007/s13312-025-00077-7","url":null,"abstract":"<p><p>We provide recommendations on neonatal noninvasive ventilation (NIV) strategies used in the delivery room (DR) and neonatal intensive care unit (NICU). A systematic search was performed in the PubMed, Embase, and CENTRAL databases to identify relevant literature from the past 5 years. A critical review of the available literature was conducted to provide context-specific recommendations. In the DR, we recommend using nasal continuous positive airway pressure (NCPAP) or nasal intermittent positive pressure ventilation (NIPPV) with a T-piece resuscitator (TPR). Surfactant replacement therapy should be administered early (< 2 h of life) in infants requiring NCPAP of 6-7 cm H<sub>2</sub>O and FiO<sub>2</sub> > 0.3, using less invasive surfactant administration techniques. Infants should be transported to the NICU on positive pressure support using NCPAP or TPR. In extremely preterm infants with severe respiratory distress requiring intubation in the DR, surfactant should be considered during the intubation. If equipment and expertise are available in the NICU, NIPPV is the preferred mode of NIV. Nasal masks or short binasal prongs are the preferred nasal interfaces. A heated, humidified, high flow nasal cannula is not recommended as the primary mode of NIV. Additional clinical trials are needed for nasal high frequency ventilation and noninvasive ventilation neurally adjusted ventilatory assist modes of NIV. Guidelines for the recommended initial and maximal settings for primary, post-extubation, and weaning off NIV in neonates are provided in this article. NIPPV and NCPAP are the preferred modes of NIV in neonates with respiratory distress.</p>","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"451-460"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12106148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of Clinical Risk Index for Babies (CRIB) II Score and Extended Sick Neonatal Score (ESNS) as a Predictor of In-hospital Mortality in Premature Neonates with Gestational Age ≤ 32 Weeks.","authors":"Goolla Akhila, Jasashree Choudhury, Vijay Kumar Krishnegowda, Debasish Nanda","doi":"10.1007/s13312-025-00107-4","DOIUrl":"https://doi.org/10.1007/s13312-025-00107-4","url":null,"abstract":"<p><strong>Objective: </strong>To compare Clinical Risk Index for Babies (CRIB) II score and Extended Sick Neonatal Score (ESNS) for predicting in-hospital mortality in premature neonates with gestational age ≤ 32 weeks.</p><p><strong>Method: </strong>This prospective observational study included 110 preterm neonates less than equal to 32 weeks of gestation. Clinical parameters of CRIB II score and ESNS were documented at time of admission and laboratory parameter were obtained with 24 h. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and likelihood ratio of the two scores as a predictor of mortality were compared.</p><p><strong>Result: </strong>The sensitivity, specificity, PPV, NPV and the Area under the Receiver Operating Characteristic (ROC) curve of CRIB II score at a cut-off value of ≥ 10 were 85.2%, 96.4%, 88.5%, 95.2%, ands 0.91 (95%CI 0.83, 0.98) respectively. The corresponding values for ESNS at a cut-off value of ≤ 11, were 77.8%, 71.1%, 46.7%, 90.8% and 0.85 (95%CI 0.78, 0.92) respectively. CRIB II score had better predictive accuracy for in-hospital mortality among premature neonates compared to ESNS (0.93 v 0.73).</p><p><strong>Conclusion: </strong>Both CRIB II and ESNS are useful tools to predict the risk of mortality during hospital stay in premature neonates. However, CRIB II score has a better predictive ability for in-hospital mortality in comparison with ESNS.</p>","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144158255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of Vitamin B12, Folate, and Iron Deficiency in Adolescents in the Yadadri-Bhuvanagiri District of Telangana: a Community-based Study.","authors":"Emine A Rahiman, Gomathi Ramaswamy, Rajendra Prasad Anne, Sangeetha Sampath, Patil Parag Parshuram","doi":"10.1007/s13312-025-00096-4","DOIUrl":"https://doi.org/10.1007/s13312-025-00096-4","url":null,"abstract":"<p><strong>Objectives: </strong>To determine the prevalence of anemia and iron, folate, and vitamin B12 deficiency in the adolescents of Yadadri-Bhuvanagiri district of Telangana.</p><p><strong>Methods: </strong>A cross-sectional community-based study was conducted. Prevalence of anemia and micronutrient deficiencies were calculated and analyzed for age, sex, socio-economic status, diet, menstruation, and growth.</p><p><strong>Results: </strong>The prevalence of anemia and deficiency of iron, vitamin B12 and folate was 34.1%, 29.2%, 77.4%, and 8.7%. Anemia and iron deficiency were higher in girls compared to boys (41.2% vs 20.9%,, P < 0.001; 39.5% vs 9.8%, P < 0.001) and girls in active menstruation (44.6% vs 12.1%; 42.3% vs 21.2%, P < 0.001). Anemia was more in older girls (15-19 years) compared to those aged 10-14 years (50% vs 28.9%; P < 0.001).</p><p><strong>Conclusions: </strong>Anemia is a significant health problem for older girls. Vitamin B12 deficiency is prevalent in nearly three-fourths of adolescents.</p>","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Adherence of Children to the Indian Academy of Pediatrics (IAP) Guidelines on Permissible Daily Screen Exposure-A Hospital-Based Cross-Sectional Study from Southern India.","authors":"Siva Sai Sushumna Veluguri, Diptirekha Satapathy, Thirunavukkarasu Arun Babu, Vinothkumar Kalidoss","doi":"10.1007/s13312-025-00097-3","DOIUrl":"https://doi.org/10.1007/s13312-025-00097-3","url":null,"abstract":"<p><p>This study assessed the adherence to IAP guidelines on permissible daily screen exposure in 771 children aged 3 months to 14 years using a pre-validated questionnaire. The mean (SD) screen time (ST) was 2.62 (1.44) hours, with adherence rates of 1%, 8.8%, 3.2%, and 24.6% in children aged < 2 years, 2-5 years, 6-10 years, and 11-14 years, respectively. Factors like age, siblings, family size, school type, and home gadgets significantly influenced ST. Novel strategies and implementation techniques should be adopted to improve adherence among children.</p>","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk Stratification-Based Therapy for Children with E-beta Thalassemia: A 20-Year Follow-Up Study.","authors":"Kavitha Ganesan, Suresh Duraisamy, Anupama Nair, Vijayshree Muthukumar, Anurag Nalla Reddy, Minakshi Balwani, Nithya Seshadri, Ramya Uppuluri, Revathi Raj","doi":"10.1007/s13312-025-00089-3","DOIUrl":"https://doi.org/10.1007/s13312-025-00089-3","url":null,"abstract":"<p><strong>Objective: </strong>To present risk stratification-based follow-up of children with E-beta thalassemia.</p><p><strong>Methods: </strong>Children with E-beta thalassemia between August 2002 and August 2022 were classified as mild, moderate, or severe disease using Mahidol scoring. Children in the moderate group with < 20 or ≥ 20 nucleated red blood cells (nRBCs) per 100 white blood cells were clubbed with mild or severe phenotype, respectively. Children with mild/moderate severity received hydroxyurea (HU) and those with severe disease received regular transfusions.</p><p><strong>Results: </strong>Out of 104 children (median age of onset 3.5 years), 30 (29%), 46 (44%), and 28 (27%) were categorized as mild, moderate, and severe disease, at initial presentation. Based on nRBC count, 27 and 19 children in moderate category were recategorized as mild to moderate and moderate to severe. Fifty-six, 19, and 29 children received HU, transfusions with HU, and monthly transfusion and chelation, respectively. At a median follow-up of 8 years, 67/93 (72%) children classified as \"mild to moderate\" remained well on HU, and 26/93 (28%) children classified as \"moderate to severe\" remained on regular transfusions.</p><p><strong>Conclusion: </strong>Using nRBCs in addition to Mahidol scoring can serve as a useful tool to individualize therapy.</p>","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Indian pediatricsPub Date : 2025-05-26DOI: 10.1007/s13312-025-00101-w
Akanksha Mahajan, Mukta Mantan
{"title":"An Update of the KDIGO Chronic Kidney Disease Guidelines 2024: Takeaway for Pediatricians.","authors":"Akanksha Mahajan, Mukta Mantan","doi":"10.1007/s13312-025-00101-w","DOIUrl":"https://doi.org/10.1007/s13312-025-00101-w","url":null,"abstract":"<p><p>Revised KDIGO (Kidney Disease: Improving Global Outcomes) Chronic Kidney Disease (CKD) guidelines have been published in 2024 with salient modifications to the previous version published in 2012. The guidelines provide management details for both adults and children with CKD. Herein, we highlight the practice points for pediatric population.</p>","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Skin Damage Risk and its Severity Caused by Pulse Oximetery Saturation Probe Attachment in Preterm Neonates: A Prospective Observational Study from Western India.","authors":"Aditya Hemendra Bhatt, Dipen Vasudev Patel, Reshma Kushal Pujara, Mayur Kiran Shinde, Somashekhar Marutirao Nimbalkar","doi":"10.1007/s13312-025-00100-x","DOIUrl":"https://doi.org/10.1007/s13312-025-00100-x","url":null,"abstract":"<p><p>A six-month prospective study assessed 94 preterm neonates using neonatal skin condition score (NSCS) at the site of peripheral capillary oxygen saturation (SpO<sub>2</sub>) probe attachment. Skin damage (NSCS > 3) occurred in 70.21% of neonates at least once. The severity of skin injury was associated with lower gestational age, lower birth weight, and poor outcomes.</p>","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Indian pediatricsPub Date : 2025-05-22DOI: 10.1007/s13312-025-00091-9
Anuradha Khadilkar, Chirantap Oza, Neha Sanwalka, Neha Kajale, Vivek Patwardhan, Dipali Ladkat, Alex Ireland, Raja Padidela, Vaman Khadilkar
{"title":"Reference Data for Lunar iDXA for the Assessment of Bone Health in Indian Children and Youth: A Cross-Sectional Study.","authors":"Anuradha Khadilkar, Chirantap Oza, Neha Sanwalka, Neha Kajale, Vivek Patwardhan, Dipali Ladkat, Alex Ireland, Raja Padidela, Vaman Khadilkar","doi":"10.1007/s13312-025-00091-9","DOIUrl":"https://doi.org/10.1007/s13312-025-00091-9","url":null,"abstract":"<p><strong>Objective: </strong>Dual energy x-ray absorptiometry (DXA) is the commonest bone densitometry technique in children. As no pediatric reference database for Indian children using a narrow fan beam densitometer is available, the aim of the study was to provide sex- and age-specific reference percentile curves for the assessment of bone health using the Lunar iDXA in 1-19-year-old Indian children.</p><p><strong>Methods: </strong>A cross-sectional study was carried out between November 2017 and July 2022 involving 1247 (607 girls) healthy children from Pune, India. The bone mineral content [BMC (g)], bone area [BA (cm<sup>2</sup>)], and bone mineral density [BMD (g/cm<sup>2</sup>)] were measured using the GE-Lunar iDXA narrow-angle fan beam scanner. Reference percentile curves were generated for total body BMC (TBBMC), total body BA (TBBA), lumbar spine bone mineral apparent density [BMAD (g/cm<sup>3</sup>)], and left femoral neck BMAD. Additionally, we provided percentile curves for TBBA relative to height, TBBMC relative to TBBA, lean body mass (LBM) relative to height, and TBBMC relative to LBM.</p><p><strong>Results: </strong>Mean (SD) bone parameters were expressed by age groups for boys and girls separately. The average annual age-related increase in TBBMD, lumbar spine BMD, and femoral neck BMD was 6.3, 7.2, and 4.5%, respectively, across different age groups. The median TBBA and TBBMC for height were higher in boys than girls by 14.7 and 24.9%, respectively. Similarly, the median TBBMC for LBM was 36.8% higher in boys as compared to girls.</p><p><strong>Conclusion: </strong>The study reports reference curves for DXA parameters (narrow fan beam) for Indian children and youth.</p>","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}