2023年昌迪加尔麻疹暴发调查:病例系列

IF 1.7 4区 医学 Q2 PEDIATRICS
Vidushi Mahajan, Mini P Singh, Anjali Sharma, Poonam Kanta, Shivani Gupta, Vishal Guglani
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引用次数: 0

摘要

目的:调查2023年印度北部某三级保健中心麻疹病毒(MeV)暴发情况。方法:使用世卫组织麻疹暴发工具箱对2023年1月1日至2023年9月30日期间印度昌迪加尔一家三级医院的疑似和确诊麻疹病例进行定义。实验室确认是基于麻疹IgM血清学阳性。根据疾病控制中心的规程,对实验室确诊病例采用实时聚合酶链反应进行基因分型。结果:38例实验室确诊病例中,18例(47%)为婴儿;结论:2023年的疫情凸显了免疫缺口的严重影响,需要持续开展疫苗接种工作,并考虑提前两剂接种计划,以防止未来发生类似事件。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Measles Outbreak Investigation in Chandigarh in 2023: A Case Series.

Objective: To investigate the measles virus (MeV) outbreak at a tertiary-care centre of northern India in 2023.

Methods: Probable and confirmed cases of measles presenting to from a tertiary hospital in Chandigarh, India, between January 01, 2023, and September 30, 2023, were defined using the WHO measles outbreak toolbox. Laboratory confirmation was based on positive IgM serology for measles. Laboratory-confirmed cases were subjected to genotyping by real-time polymerase chain reaction as per the Centre for Disease Control protocol.

Results: Out of 38 laboratory-confirmed cases, 18 (47%) were infants; 10 out of 18 infants were aged < 9 months. 60% cases were unvaccinated for MeV. Genotyping in 3 out of 5 cases revealed the D8 genotype, MeV strain MVs/Thiruvananthapuram. IND/18.12 in circulation.

Conclusion: The 2023 outbreak underscores the critical impact of the immunization gap, need for sustained vaccination efforts and to consider early 2-dose schedule to prevent similar occurrences in the future.

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来源期刊
Indian pediatrics
Indian pediatrics 医学-小儿科
CiteScore
3.30
自引率
8.70%
发文量
344
审稿时长
3-8 weeks
期刊介绍: The general objective of Indian Pediatrics is "To promote the science and practice of Pediatrics." An important guiding principle has been the simultaneous need to inform, educate and entertain the target audience. The specific key objectives are: -To publish original, relevant, well researched peer reviewed articles on issues related to child health. -To provide continuing education to support informed clinical decisions and research. -To foster responsible and balanced debate on controversial issues that affect child health, including non-clinical areas such as medical education, ethics, law, environment and economics. -To achieve the highest level of ethical medical journalism and to produce a publication that is timely, credible and enjoyable to read.
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