Vidushi Mahajan, Mini P Singh, Anjali Sharma, Poonam Kanta, Shivani Gupta, Vishal Guglani
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Measles Outbreak Investigation in Chandigarh in 2023: A Case Series.
Objective: To investigate the measles virus (MeV) outbreak at a tertiary-care centre of northern India in 2023.
Methods: Probable and confirmed cases of measles presenting to from a tertiary hospital in Chandigarh, India, between January 01, 2023, and September 30, 2023, were defined using the WHO measles outbreak toolbox. Laboratory confirmation was based on positive IgM serology for measles. Laboratory-confirmed cases were subjected to genotyping by real-time polymerase chain reaction as per the Centre for Disease Control protocol.
Results: Out of 38 laboratory-confirmed cases, 18 (47%) were infants; 10 out of 18 infants were aged < 9 months. 60% cases were unvaccinated for MeV. Genotyping in 3 out of 5 cases revealed the D8 genotype, MeV strain MVs/Thiruvananthapuram. IND/18.12 in circulation.
Conclusion: The 2023 outbreak underscores the critical impact of the immunization gap, need for sustained vaccination efforts and to consider early 2-dose schedule to prevent similar occurrences in the future.
期刊介绍:
The general objective of Indian Pediatrics is "To promote the science and practice of Pediatrics." An important guiding principle has been the simultaneous need to inform, educate and entertain the target audience. The specific key objectives are:
-To publish original, relevant, well researched peer reviewed articles on issues related to child health.
-To provide continuing education to support informed clinical decisions and research.
-To foster responsible and balanced debate on controversial issues that affect child health, including non-clinical areas such as medical education, ethics, law, environment and economics.
-To achieve the highest level of ethical medical journalism and to produce a publication that is timely, credible and enjoyable to read.