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BIOCONJUGATE OF R-PHYCOERYTHRIN WITH AG0 NANOPARTICLE – FUNCTIONAL NANOSTRUCTURE FOR CANCER THERANOSTICS, FLUORESCENT BIOSENSORS AND ELECTROCHEMICAL BIOINTERFACES r -植氰菊酯与ag0纳米粒子的生物偶联——用于癌症治疗、荧光生物传感器和电化学生物界面的功能纳米结构
http://eng.biomos.ru/conference/articles.htm Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-73-75
B. Kurganov
{"title":"BIOCONJUGATE OF R-PHYCOERYTHRIN WITH AG0 NANOPARTICLE – FUNCTIONAL NANOSTRUCTURE FOR CANCER THERANOSTICS, FLUORESCENT BIOSENSORS AND ELECTROCHEMICAL BIOINTERFACES","authors":"B. Kurganov","doi":"10.37747/2312-640x-2021-19-73-75","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-73-75","url":null,"abstract":"Bioconjugate Ag‧PE was obtained by the synthesis of silver nanoparticles in the phycoerythrin tunnel cavity without an exogenous reducing agent. Physicochemical properties of the conjugate and analysis of published data indicate that Ag‧PE can find application for diagnostics and therapy (theranostics) of cancer, as well as fluorescent biosensors and electrochemical biointerfaces.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75783708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ENZYMES AS TARGETS FOR THE EFFECTS OF ORGANOPHOSPHORUS COMPOUNDS AND THEIR BIOCATALYTIC DETOXIFIERS: A NEW LOOK AT A WELL-KNOWN PROBLEM 酶作为有机磷化合物及其生物催化解毒剂作用的靶标:一个众所周知的问题的新视角
http://eng.biomos.ru/conference/articles.htm Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-269-271
A. Aslanli, I. Lyagin
{"title":"ENZYMES AS TARGETS FOR THE EFFECTS OF ORGANOPHOSPHORUS COMPOUNDS AND THEIR BIOCATALYTIC DETOXIFIERS: A NEW LOOK AT A WELL-KNOWN PROBLEM","authors":"A. Aslanli, I. Lyagin","doi":"10.37747/2312-640x-2021-19-269-271","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-269-271","url":null,"abstract":"The conducted studies made it possible to identify new targets in the form of the most important decarboxylases for the possible negative effects of known organophosphorus compounds and to assess their potential danger to humans.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"2012 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78914584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ABILITY OF AURICULARIA AURICULAR-JUDAE EXTRACT TO SUPPRESS INFLUENZA VIRUS REPRODUCTION 木耳提取物对流感病毒繁殖的抑制作用
http://eng.biomos.ru/conference/articles.htm Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-178-179
A. Potekhina, P. Alexyuk, I. Zaitseva, N. Sokolova, E.S. Omirtayeva, M. Alexyuk, A. P. Bogoyavlenskiy, V. Berezin
{"title":"ABILITY OF AURICULARIA AURICULAR-JUDAE EXTRACT TO SUPPRESS INFLUENZA VIRUS REPRODUCTION","authors":"A. Potekhina, P. Alexyuk, I. Zaitseva, N. Sokolova, E.S. Omirtayeva, M. Alexyuk, A. P. Bogoyavlenskiy, V. Berezin","doi":"10.37747/2312-640x-2021-19-178-179","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-178-179","url":null,"abstract":"The ability of the Auricularia auricular-judae extract to suppress the reproduction of the influenza virus was studied. It was shown that the index of the therapeutic activity of the extract is comparable to that of commercial preparations Tamiflu and Remantadine.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"149 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74765473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
APPLICATION OF THE PREPARATION FROM MICROSCOPIC FUNGI IN THE TECHNOLOGY OF FRUIT PROCESSING BEFORE LAYING FOR STORAGE 微真菌制剂在水果铺存前加工技术中的应用
http://eng.biomos.ru/conference/articles.htm Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-304-306
I. I. Grigorevskaya, E. Yushina
{"title":"APPLICATION OF THE PREPARATION FROM MICROSCOPIC FUNGI IN THE TECHNOLOGY OF FRUIT PROCESSING BEFORE LAYING FOR STORAGE","authors":"I. I. Grigorevskaya, E. Yushina","doi":"10.37747/2312-640x-2021-19-304-306","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-304-306","url":null,"abstract":"The use of the preparation from the biomass of the micromycete Mortierella polycephala provides an increase in the reliability of protection of fruits from microbial spoilage and an increase in the shelf life of fruits.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83772254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
STRUCTURAL FEATURES OF PHOSPHOTRIESTERASES HYDROLYZING ORGANOPHOSPHATES WITH AN INACTIVATED LEAVING GROUP 具有灭活离去基水解有机磷的磷酸三酯酶的结构特征
http://eng.biomos.ru/conference/articles.htm Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-122-123
T. I. Mulashkina, A. Kulakova
{"title":"STRUCTURAL FEATURES OF PHOSPHOTRIESTERASES HYDROLYZING ORGANOPHOSPHATES WITH AN INACTIVATED LEAVING GROUP","authors":"T. I. Mulashkina, A. Kulakova","doi":"10.37747/2312-640x-2021-19-122-123","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-122-123","url":null,"abstract":"The mechanism of hydrolysis of organophosphates, dibutyl-4-nitro-phenylphosphate and its analogue with an inactivated leaving group – dibutylphenylphosphate by phosphotriesterase Pd-PTE has been determined.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"100 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89435808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
INTERACTIONS OF ANTICANCER DRUGS – ABIRATERONE AND GALETERONE – WITH CYTOCHROME P450 51A1 (CYP51A1) 抗癌药物阿比特龙和加莱酮与细胞色素p450 51a1 (cyp51a1)的相互作用
http://eng.biomos.ru/conference/articles.htm Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-149-150
A. Kuzikov, A. Veselovsky, I. Toropygin, A. Archakov, V. Shumyantseva
{"title":"INTERACTIONS OF ANTICANCER DRUGS – ABIRATERONE AND GALETERONE – WITH CYTOCHROME P450 51A1 (CYP51A1)","authors":"A. Kuzikov, A. Veselovsky, I. Toropygin, A. Archakov, V. Shumyantseva","doi":"10.37747/2312-640x-2021-19-149-150","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-149-150","url":null,"abstract":"Interactions of abiraterone and galeterone with steroid-metabolizing cytochrome P450 (CYP51A1) was studied. Binding of substrate type was observed, which indicates possible metabolism of abiraterone and galeterone by CYP51A1, however electrocatalytic reaction only towards abiraterone was observed.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"107 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75019425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MODELING CHANGES IN THE ADAPTABILITY AND MOTILITY OF MICROORGANISMS IN CHANGING AQUATIC ECOSYSTEMS 模拟变化的水生生态系统中微生物的适应性和运动性变化
http://eng.biomos.ru/conference/articles.htm Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-203-204
A. Klimenko, S. Lashin
{"title":"MODELING CHANGES IN THE ADAPTABILITY AND MOTILITY OF MICROORGANISMS IN CHANGING AQUATIC ECOSYSTEMS","authors":"A. Klimenko, S. Lashin","doi":"10.37747/2312-640x-2021-19-203-204","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-203-204","url":null,"abstract":"The results of our simulations show that motile forms (as opposed to sedentary forms) have an advantage under nutrient-poor conditions corresponding to the environment in which marine bacteria live. There is a turning point in the magnitude of the migration penalty that determines whether the Nomadic strategy will be successful or not.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73865423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
AN UNUSUAL SYSTEM BASED ON SULFUR-CONTAINING AMINO ACIDS AND SILVER SALTS: FROM SELF-ORGANIZATION TO APPLICATION PROSPECTS 一种基于含硫氨基酸和银盐的特殊体系:从自组织到应用前景
http://eng.biomos.ru/conference/articles.htm Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-16-18
D. Vishnevetskii, A. R. Mekhtiev, S. Khizhnyak, P. Pakhomov
{"title":"AN UNUSUAL SYSTEM BASED ON SULFUR-CONTAINING AMINO ACIDS AND SILVER SALTS: FROM SELF-ORGANIZATION TO APPLICATION PROSPECTS","authors":"D. Vishnevetskii, A. R. Mekhtiev, S. Khizhnyak, P. Pakhomov","doi":"10.37747/2312-640x-2021-19-16-18","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-16-18","url":null,"abstract":"Reversible hydrogels containing silver nanoparticles stabilized by the amino acid L-cysteine in their volume were obtained. The silver salt that initiates gelation - nitrite, nitrate and acetate - affects the bioactive properties of the final material and various possibilities for its modification.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"33 7-8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77653547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
NANODISPERSIONS OF LIPOIC ACID: PRODUCTION AND STUDY OF INFLUENCE ON FUNCTIONAL ACTIVITY OF PLATELETS 硫辛酸纳米分散体的生产及其对血小板功能活性影响的研究
http://eng.biomos.ru/conference/articles.htm Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-101-104
A. M. Inshakova, E. Darnotuk, A. Shipelova, N. Shastina, O. Baranova, A. Chekanov, K. Kazarinov, E. Solovieva, A. Fedin
{"title":"NANODISPERSIONS OF LIPOIC ACID: PRODUCTION AND STUDY OF INFLUENCE ON FUNCTIONAL ACTIVITY OF PLATELETS","authors":"A. M. Inshakova, E. Darnotuk, A. Shipelova, N. Shastina, O. Baranova, A. Chekanov, K. Kazarinov, E. Solovieva, A. Fedin","doi":"10.37747/2312-640x-2021-19-101-104","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-101-104","url":null,"abstract":"Various nanodispersions (liposomes and nanoemulsions) with lipoic acid (LA) with size of particles 50-250 nm were obtained and characterized by 80±10% encapsulation efficiency (EI) of LA into NPs, its slow release from nanoconstructions, and possessing stability during long-term storage at room temperature. It was revealed that liposomes and LA NPs inhibit platelet aggregation caused by arachidonic acid, and the mechanism of antiplatelet action was proposed.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"98 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77345109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MODERN BIOCATALYTIC TECHNOLOGIES FOR PROTECTIVE MATERIALS AGAINST BIOLOGICAL AND CHEMICAL AGENTS 防止生物和化学制剂的防护材料的现代生物催化技术
http://eng.biomos.ru/conference/articles.htm Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-275-276
N. V. Zavyalova, V. Zavyalov, V. Gorelenkov, G. Frolov, N. Stepanov, A. Aslanli, E. Efremenko
{"title":"MODERN BIOCATALYTIC TECHNOLOGIES FOR PROTECTIVE MATERIALS AGAINST BIOLOGICAL AND CHEMICAL AGENTS","authors":"N. V. Zavyalova, V. Zavyalov, V. Gorelenkov, G. Frolov, N. Stepanov, A. Aslanli, E. Efremenko","doi":"10.37747/2312-640x-2021-19-275-276","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-275-276","url":null,"abstract":"Modern innovative approaches which can be applied to obtain universal protective materials with a wide spectrum of action are analyzed.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"38 4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78332785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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