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Microbial production of L-lysine: a review. 微生物生产l -赖氨酸的研究进展。
Hindustan antibiotics bulletin Pub Date : 1997-02-01
M Chatterjee, S P Chatterjee
{"title":"Microbial production of L-lysine: a review.","authors":"M Chatterjee,&nbsp;S P Chatterjee","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Microbial production of L-lysine has been reviewed with 251 references. The review includes different lysine producing microorganisms, their optimum cultural conditions, yield, assay and process of product recovery. It includes a discussion on the pathway of aspartate family of amino acid's biosynthesis in bacteria and its regulation. Achievements in this regard made through genetic engineering have also been included.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"39 1-4","pages":"20-49"},"PeriodicalIF":0.0,"publicationDate":"1997-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21254351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Auxotrophic requirement for sporangiospore--yeast transformation of Dimorphomyces diastaticus strain C 12. 孢囊孢子的营养缺陷需求——分散二形态菌c12的酵母转化。
Hindustan antibiotics bulletin Pub Date : 1997-02-01
C O Omoifo
{"title":"Auxotrophic requirement for sporangiospore--yeast transformation of Dimorphomyces diastaticus strain C 12.","authors":"C O Omoifo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The filamentous microorganism tentatively known as Dimorphomyces diastaticus originally isolated from fermenting soursop extract, in contradistinction grew in the considiogeneous form in glucose-ammonium sulphate-basal salts buffered medium which induced polar budding yeast cells of another dimorphic microorganism, D. pleomorphis (1). Further experiments using this medium showed that a number of growth factors including inositol, thymine and uracil separately incorporated inducted yeast morphology. Carbon substrates gave rise to polar budding yeast cells in the following order: galactose, malic acid, maltose, but mycelial fragments were preponderant in the reverse order. There was no growth with citric acid as substrate. With maltose-substrate and uracil incorporation in buffered basal salts medium, only polar budding yeast cells were induced, while granular particles abound with thymine supplementation. It was concluded that D. diastaticus strain C12 auxotrophically required a dissacharide, maltose, and pyrimidine base, uracil, for sporangiospore-yeast transformation in buffered ammonium sulphate-basal salts medium, pH 3.5.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"39 1-4","pages":"11-5"},"PeriodicalIF":0.0,"publicationDate":"1997-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21254347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimisation of cultural conditions for antifungal antibiotic accumulation by Streptomyces rochei G164. 罗氏链霉菌G164抗真菌积累条件的优化
Hindustan antibiotics bulletin Pub Date : 1997-02-01
D Chattopadhyay, S K Sen
{"title":"Optimisation of cultural conditions for antifungal antibiotic accumulation by Streptomyces rochei G164.","authors":"D Chattopadhyay,&nbsp;S K Sen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To induce higher amount of antifungal antibiotic production by variation of cultural parameters has been studied. The maximum effectivity was found in sucrose as carbon source, peptone as nitrogen source and at pH 7.0. The effect of other selected factors were also evaluated in order to judge the variables that influenced antibiotic production.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"39 1-4","pages":"64-71"},"PeriodicalIF":0.0,"publicationDate":"1997-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21253650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Awareness of non-hormonal contraceptive (SAHELI) among subjects using MTP services. 使用MTP服务的受试者对非激素避孕(SAHELI)的认识。
Hindustan antibiotics bulletin Pub Date : 1996-02-01
A Vatsayan, A K Gupta, R Sood
{"title":"Awareness of non-hormonal contraceptive (SAHELI) among subjects using MTP services.","authors":"A Vatsayan,&nbsp;A K Gupta,&nbsp;R Sood","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"38 1-4","pages":"66"},"PeriodicalIF":0.0,"publicationDate":"1996-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20593847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antifungal activity (invitro) of certain polyene macrolide antibiotics against various plant pathogens. 某些多烯环内酯类抗生素对多种植物病原菌的体外抗真菌活性。
Hindustan antibiotics bulletin Pub Date : 1996-02-01
J M Bhat, M S Narayanan
{"title":"Antifungal activity (invitro) of certain polyene macrolide antibiotics against various plant pathogens.","authors":"J M Bhat,&nbsp;M S Narayanan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Certain polyene macrolides were developed from different actinomycetes at Research and Development of Hindustan Antibiotics Limited. These antibiotics were screened for the antifungal activity against various plant pathogens. IC50 and MIC of each of the antibiotic against the plant pathogens was found out and is being reported.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"38 1-4","pages":"32-6"},"PeriodicalIF":0.0,"publicationDate":"1996-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20593836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modelling Sporangiospore-yeast transformation of Dimorphomyces strain. 双形态菌孢子-酵母菌转化的模拟。
Hindustan antibiotics bulletin Pub Date : 1996-02-01
C O Omoifo
{"title":"Modelling Sporangiospore-yeast transformation of Dimorphomyces strain.","authors":"C O Omoifo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Two types of buffered media, strictly defined-Ammonium sulphate-basal salts and complex Peptone-basal salts, were used for the cultivation of Dimorphomyces pleomorphis, one of two dimorphic fungi isolated from fermenting juice of soursop fruit, Annona muricata L. The growth count was taken every twenty-four hours. Transient morphologies were observed to change from sporangiospores through enlarged globose cells, to granular particles and eventually, polar budding yeast cells in the strictly defined medium at 15 degrees, 20 degrees, or 37 degrees C, but the complex medium casually terminally induced polar budding yeast cells and multipolar budding yeast like cells in between the growth phases, at 15 degrees and 20 degrees C, while mainly multipolar budding yeastlike morphology was observed at elevated temperature. There was obvious influence of nutritional factor or morphological expression (p < 0.01). After analysis of variance, the growth data could not fit into predictive quadratic polynomial model because the organism's response curves were incongruent with basic assumptions of the model. Furthermore, a stepwise regression analysis gave very low coefficients of determination, r2, for the interactive combinations. They were therefore, considered unfit for the data. Construction of the pII-profiles led to inference being drawn from the chemiosmotic theory, polyelectrolyte theory to account for the behaviour in the buffered multiionic media. It was also thought that inherent cellular mitotic division and glycolytic activity led to a prelogarithmic growth response.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"38 1-4","pages":"12-31"},"PeriodicalIF":0.0,"publicationDate":"1996-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20593835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In vitro evaluation of medicinal plant extracts against Pestalotiopsis mangiferae. 药用植物提取物抗芒芒拟盘多毛孢的体外评价。
Hindustan antibiotics bulletin Pub Date : 1996-02-01
M K Rai
{"title":"In vitro evaluation of medicinal plant extracts against Pestalotiopsis mangiferae.","authors":"M K Rai","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A serious leaf-spot disease of Mangifera indica was noted during the last 10 years in Satpura plateau of India. On the basis of characteristic symptoms and cultural characters, the pathogen was identified as Pestalotiopsis mangiferae which is hitherto not reported from Satpura plateau of India. Screening of 17-medicinal plants against the test pathogen revealed 14 antimycotic whereas 3-plants, viz., Argemone mexicana, Caesalpinia bonducella, and Casia fistula acclerated the growth of the pathogen. The maximum activity was shown by Eucalyptus globulus (88%) and Catharanthus roseus (88%) followed by Ocimum sanctum (85.50%), Azadirachta indica (84.66%), Ricinus communis (75%) and Lawsonia inermis (74.33%) while the minimum activity was exhibited by Jatropha curcas (10%).</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"38 1-4","pages":"53-6"},"PeriodicalIF":0.0,"publicationDate":"1996-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20593842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of product analogues for purification of penicillinase by affinity chromatography. 亲和层析纯化青霉酶产物类似物的评价。
Hindustan antibiotics bulletin Pub Date : 1996-02-01
K K Kumar, B S Deshpande, S S Ambedkar, J G Shewale
{"title":"Evaluation of product analogues for purification of penicillinase by affinity chromatography.","authors":"K K Kumar,&nbsp;B S Deshpande,&nbsp;S S Ambedkar,&nbsp;J G Shewale","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Among different matrices prepared, ampicilloic acid-polymer matrix offered 86.7% adsorption, 95% elution and 82.4% overall recovery of penicillinase. The structure of both the side chain and penicilloic or cephalosporoic acid moieties contribute to the affinity interactions.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"38 1-4","pages":"37-40"},"PeriodicalIF":0.0,"publicationDate":"1996-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20593838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Production of extracellular protease by Streptomyces fradiae. 传统链霉菌胞外蛋白酶的生产。
Hindustan antibiotics bulletin Pub Date : 1996-02-01
P Ellaiah, B Srinivasulu
{"title":"Production of extracellular protease by Streptomyces fradiae.","authors":"P Ellaiah,&nbsp;B Srinivasulu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A new strain of Streptomyces fradiae, isolated and identified in our laboratory, was found to be a potential producer of protease enzyme. An enzyme yield of 285 P.U./ml. was obtained prior to optimization in a synthetic medium containing potato starch, potassium nitrate and trace salts by shake flask method. The carbon and nitrogen compounds play prominent role in the protease production. The maximum enzyme yield of 930 P.U./ml. (about 3-fold increase) was obtained with all optimum parameters such as pH. 7.0, with 3% jowar starch, 0.5% tryptone, 28 degrees C incubation temperature, with 1:20 medium to flask volume ratio and with 48 hrs. inoculum.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"38 1-4","pages":"41-7"},"PeriodicalIF":0.0,"publicationDate":"1996-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20593840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Isolation and characterisation of bioactive actinomycetes from marine sediments. 海洋沉积物中生物活性放线菌的分离与鉴定。
Hindustan antibiotics bulletin Pub Date : 1996-02-01
P Ellaiah, D Kalyan, V S Rao, B V Rao
{"title":"Isolation and characterisation of bioactive actinomycetes from marine sediments.","authors":"P Ellaiah,&nbsp;D Kalyan,&nbsp;V S Rao,&nbsp;B V Rao","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Actinomycetes (28) were isolated from marine sediments off Madras coast by plating on Starch-Casein Agar medium. After preliminary studies, five isolates which were found to be promising were selected for detailed morphological, cultural, Physiological and biochemical studies. The genera encountered were Streptomycetes. Out of these five isolates, three isolates exhibited very good broad spectrum antibacterial activity. The sodium chloride tolerance of these five isolates was also tested.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"38 1-4","pages":"48-52"},"PeriodicalIF":0.0,"publicationDate":"1996-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20593844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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