{"title":"Effect of dissolved oxygen levels on biosynthesis of aureofungin by Streptoverticillium cinnamoneum var. terricola.","authors":"P V Patankar, R K Nanda, S R Naik","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Biosynthesis of aureofungin by Streptoverticillium cinnamoneum var, terricola was found to be an oxygen dependent reaction. An accelerated rate of aureofungin production, along with a better yield coefficient were obtained under conditions of enhanced aeration during fermentation. A higher oxygen transfer rate was found to stimulate aureofungin A, and suppresses aureofungin B formation.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"36 1-2","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"1994-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18739783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H K Malviya, M P Golwalkar, M S Narayanan, G D Tandon
{"title":"Preliminary studies on a Streptomyces sp. CS-14 showing broad spectrum antibiotic activity.","authors":"H K Malviya, M P Golwalkar, M S Narayanan, G D Tandon","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A Streptomyces sp. CS-14 producing antifungal and antibacterial antibiotics has been isolated and characterized. The characterization of mycelial bound antibiotic revealed the presence of a hexaene polyene macrolide whereas filtrate bound antibiotic belonged to aminoglycoside group. Both the antibiotics showed very good antimicrobial activities in vitro.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"36 1-2","pages":"21-9"},"PeriodicalIF":0.0,"publicationDate":"1994-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18739784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dermostatin A and B: chromatography, structural and configurational studies using HPLC, CCD, 13C (125 MHz) and 1H (500 MHz) NMR spectroscopy.","authors":"M B Swamy, M K Sastry, R K Nanda","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>HPLC of crude Dermostatin indicated presence of three pairs of components. Hence, attempts were made to purify Dermostatin. Purification of crude Dermostatin has been carried out using column chromatography and counter current distribution methods. Each of these fractions were tested for activity. The major fraction which showed greater activity was taken for the preparation of Dermostatin nona-acetate. Structural characterisation of Dermostatin nona-acetate has been carried out using UV-visible spectroscopy in different solvents to obtain the characteristic spectrum of a carbonyl conjugated hexaene at room temperature. Structural and configurational studies of Dermostatin nona-acetate using 500 MHz 1H NMR and 125 MHz 13C NMR has been used in the assignment of various functional groups in Dermostatin A and B as well as to provide corroboration to the earlier structural elucidation.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"36 1-2","pages":"6-20"},"PeriodicalIF":0.0,"publicationDate":"1994-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18739791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Sinhababu, B Basak, S Laskar, D Chakrabarty, S K Sen
{"title":"Effect of different fractions of petroleum ether (60-80 degrees) extract of the seeds of Lagerstroemia speciosa (Linn. ex Murray) Pers. on some microorganisms.","authors":"A Sinhababu, B Basak, S Laskar, D Chakrabarty, S K Sen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In a model experiment, seed extracts were applied to different bacterial test organisms. Different fractions of seed extracts in petroleum ether (60-80 degrees C) of Lagerstroemia speciosa (Linn. ex. Murray) Pers. when applied to both Gram positive and Gram negative test bacteria, some fractions showed high antagonistic activity.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"36 1-2","pages":"39-45"},"PeriodicalIF":0.0,"publicationDate":"1994-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18739790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Regulatory enzymes for the screening of streptomycin producing mutant strains of Streptomyces griseus.","authors":"N K Maladkar","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Intermediary enzymes of streptomycin biosynthesis-arginine amidinotransferase and alkaline phosphatase were located at the early fermentation stages. Their relationship with streptomycin production by Streptomyces griseus strains GX-19 and MR-20 was determined and the use of this relationship was made for the screening of streptomycin producing mutant strains.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"36 1-2","pages":"30-3"},"PeriodicalIF":0.0,"publicationDate":"1994-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18739786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Studies of serum gentamicin disposition after parenteral administration in ewes.","authors":"S K Toke, M M Gatne, P K Nemade, V V Ranade","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"35 3-4","pages":"212-5"},"PeriodicalIF":0.0,"publicationDate":"1993-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18956700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Streptoverticillium acido-carbonicum sp. nov.","authors":"B V Lakshmi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A new species of Streptoverticillium assignable to biverticillate series, isolated from coal mine soil, Kothagudem (A. P.) is described. It grows from pH 4.5-6.0 with an optimum at pH 5.0 and temperature 37 degrees C. Its growth characters on differential media and utilization of carbon compounds are presented.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"35 3-4","pages":"191-4"},"PeriodicalIF":0.0,"publicationDate":"1993-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18956696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of some antibiotics on Fusarium equiseti causing damping off in guar (Cyamopsis tetragonolobe (L.) Taub.","authors":"S K Dwivedi, S K Dwivedi","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"35 3-4","pages":"216-8"},"PeriodicalIF":0.0,"publicationDate":"1993-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18956601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative evaluation of determination of beta-lactam intermediates.","authors":"B S Deshpande, S S Ambedkar, J G Shewale","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The Schiff's base formation between 6-aminopenicillanic acid, 7-aminodesacetoxycephalosporanic acid and 7-aminocephalosporanic acid and p-dimethylaminobenzaldehyde (PDAB) was investigated. The factors that affect the reaction such as concentration of PDAB, time and pH were studied and optimised for estimation of these intermediates.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"35 3-4","pages":"195-8"},"PeriodicalIF":0.0,"publicationDate":"1993-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18956697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"rDNA based pharmaceuticals (selected information).","authors":"M Ghosh, A R Khape, B B Bannur","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"35 3-4","pages":"219-55"},"PeriodicalIF":0.0,"publicationDate":"1993-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18956602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}