Comparative evaluation of determination of beta-lactam intermediates.

Hindustan antibiotics bulletin Pub Date : 1993-08-01
B S Deshpande, S S Ambedkar, J G Shewale
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引用次数: 0

Abstract

The Schiff's base formation between 6-aminopenicillanic acid, 7-aminodesacetoxycephalosporanic acid and 7-aminocephalosporanic acid and p-dimethylaminobenzaldehyde (PDAB) was investigated. The factors that affect the reaction such as concentration of PDAB, time and pH were studied and optimised for estimation of these intermediates.

-内酰胺中间体测定方法的比较评价。
研究了6-氨基青霉酸、7-氨基去乙酰氧基头孢菌酸和7-氨基头孢菌酸与对二甲氨基苯甲醛(PDAB)之间的席夫碱形成。研究了影响反应的因素,如PDAB浓度、时间和pH,并对这些中间产物的估计进行了优化。
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