K K Kumar, B S Deshpande, S S Ambedkar, J G Shewale
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Evaluation of product analogues for purification of penicillinase by affinity chromatography.
Among different matrices prepared, ampicilloic acid-polymer matrix offered 86.7% adsorption, 95% elution and 82.4% overall recovery of penicillinase. The structure of both the side chain and penicilloic or cephalosporoic acid moieties contribute to the affinity interactions.
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