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Hindustan antibiotics bulletin最新文献

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A new streptomycete producing diphenyl sulfone antibiotic--S. sulfonensis. 一种新的产二苯砜类抗生素的链霉菌——S。sulfonensis。
Hindustan antibiotics bulletin Pub Date : 1998-02-01
P Ellaiah, V S Rao, B V Rao, B Srinivasulu, T A Ghani
{"title":"A new streptomycete producing diphenyl sulfone antibiotic--S. sulfonensis.","authors":"P Ellaiah,&nbsp;V S Rao,&nbsp;B V Rao,&nbsp;B Srinivasulu,&nbsp;T A Ghani","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>About 359 actinomycetes were isolated from 8 different natural substrates collected from different parts of Andhra Pradesh. The isolates were screened on the basis of their inhibitory effect against test organisms. Finally one potent antibiotic producer was chosen having broad-spectrum activity against Gram-positive and Gram-negative bacteria and it was found to produce a diphenyl sulfone antibiotic. On the basis of morphological, cultural, physiological and biochemical characters, the diphenyl sulfone antibiotic producer was identified as a new species and was designated as S. sulfonensis.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"40 1-4","pages":"31-7"},"PeriodicalIF":0.0,"publicationDate":"1998-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26244339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pharmacological evaluation of some bioactive plant products on albino rats. 一些生物活性植物产品对白化大鼠的药理评价。
Hindustan antibiotics bulletin Pub Date : 1998-02-01
T N Tiwari, J Varma, N K Dubey, J P Chansouria, Z Ali
{"title":"Pharmacological evaluation of some bioactive plant products on albino rats.","authors":"T N Tiwari,&nbsp;J Varma,&nbsp;N K Dubey,&nbsp;J P Chansouria,&nbsp;Z Ali","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The study comprises the pharmacological trials with essential oils of Caesulia axillaris, Ocimum gratissimum and Mentha arvensis which have shown strong antifungal property. The biochemical analysis of blood and serum of albino rats fed with the oil treated diet for sixty days exhibited nonanimal toxic nature of the oils. The study reveals the possibility of further exploitation of the oils as safe antifungal agents of plant origin.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"40 1-4","pages":"38-41"},"PeriodicalIF":0.0,"publicationDate":"1998-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26244341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of some essential oils on microorganisms. 一些精油对微生物的影响。
Hindustan antibiotics bulletin Pub Date : 1998-02-01
R Pandey, N Mehrotra, R Gaur, N S Darmwal
{"title":"Effect of some essential oils on microorganisms.","authors":"R Pandey,&nbsp;N Mehrotra,&nbsp;R Gaur,&nbsp;N S Darmwal","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The essential oils tested viz., Cardiaca Oil, Mentha Oil, Artemisia Oil and Geranium Oil against pathogenic bacterial and fungal strains. Significant activity of all oils was found against all microorganisms. All the four oils showed a higher inhibition against all the microorganisms, except S. epidermidis at different level of concentrations used (1000 ppm and 500 ppm). It is clearly indicated that inhibition activity increased approximately 1 to 2 folds at 1000 ppm concentration as compared to 500 ppm. S. epidermidis has shown resistant towards all the oils at both the concentration while M. smegmatis and S. mutans have shown higher inhibition as compared to S. epidermidis.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"40 1-4","pages":"59-61"},"PeriodicalIF":0.0,"publicationDate":"1998-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26244219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis and antibacterial activity of some Schiff bases and 4-thiazolidinones. 一些席夫碱和4-噻唑烷酮的合成及其抗菌活性。
Hindustan antibiotics bulletin Pub Date : 1998-02-01
R P Pawar, N M Andurkar, B R Patil, Y B Vibhute
{"title":"Synthesis and antibacterial activity of some Schiff bases and 4-thiazolidinones.","authors":"R P Pawar,&nbsp;N M Andurkar,&nbsp;B R Patil,&nbsp;Y B Vibhute","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Some new schiff bases (1a-d) 4-thiazolidinones (2a-d) have been synthesised and tested for their antibacterial activity. The structures of these compounds have been established on the basis of elemental analysis and spectral data (IR and H1 NMR).</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"40 1-4","pages":"51-3"},"PeriodicalIF":0.0,"publicationDate":"1998-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26244225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thermal stability of penicillin G acylase : effect of stabilizing agents. 稳定剂对青霉素G酰化酶热稳定性的影响。
Hindustan antibiotics bulletin Pub Date : 1998-02-01
V K More, J G Shewale, V K Sudhakaran
{"title":"Thermal stability of penicillin G acylase : effect of stabilizing agents.","authors":"V K More,&nbsp;J G Shewale,&nbsp;V K Sudhakaran","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The role of sugars, polyhydroxy compounds, phenylacetic acid and 6-aminopenicillanic acid in stabilization of immobilized penicillin G acylase (IMPGA) was studied. The loss in the activity of IMPGA at 50 degrees C, 2 h, after incorporation of sucrose and mannitol at 0.1 M concentration was 16 and 18% respectively; the loss in the activity of the enzyme under these conditions in the absence of stabilizing agents was 40%.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"40 1-4","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"1998-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26244335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Isolation and purification of penicillin G acylase obtained from Escherichia coli (NCIM-2400) and immobilisation on Eupergit C for the production of 6 amino penicillanic acid. 从大肠杆菌中分离纯化青霉素G酰化酶(NCIM-2400)并固定化Eupergit C生产6氨基青霉酸。
Hindustan antibiotics bulletin Pub Date : 1997-02-01
M M Hegde, S B Thadani, U Singh, S R Naik
{"title":"Isolation and purification of penicillin G acylase obtained from Escherichia coli (NCIM-2400) and immobilisation on Eupergit C for the production of 6 amino penicillanic acid.","authors":"M M Hegde,&nbsp;S B Thadani,&nbsp;U Singh,&nbsp;S R Naik","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Penicillin G-Acylase is produced by submerged cultivation of E. Coli (NCIM-2400) and extracted from the harvested fermented broth, purified (affinity chromatography) and immobilised on Eupergit C (Synthetic polymer in bead form). The immobilised penicillin G acylase properties are studied and compared with soluble penicillin G-acylase. The control parameters for conversion of penicillin G-K to 6 APA are optimised [e.g. substrate (Pen G-K) concentration ratio to immobilised penicillin G-acylase, temperature, pH etc.] in a stirred tank reactor. Our findings suggest that immobilised penicillin G-acylase can be used commercially and the productivity of 1 kg. of immobilised enzyme is around 400 kg of 6 APA under given desired stipulated conditions.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"39 1-4","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"1997-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21254348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Affinity chromatography of maltase on aliphatic amines as ligands. 麦芽糖酶以脂肪胺为配体的亲和层析。
Hindustan antibiotics bulletin Pub Date : 1997-02-01
M V Kulkarni, S K Karyekar
{"title":"Affinity chromatography of maltase on aliphatic amines as ligands.","authors":"M V Kulkarni,&nbsp;S K Karyekar","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The primary amino group, the competitive inhibitor of maltase, was used as ligand and the enzyme was purified to homogeneity in a single step. The amino group affiants of ethylene (C2-NH2) and hexamethylene (C6-NH2) diamines were prepared by coupling to cyanogen bromide activated Sepharose CL-4B. The enzyme was quantitatively adsorbed at alkaline pH (pH 8.2), while the elution could be effected only in presence of maltose at acidic pH. The elution of enzyme by maltose was independent of spacer arms (C2 and C6) which suggests specific binding of the enzyme through inhibitor site.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"39 1-4","pages":"16-9"},"PeriodicalIF":0.0,"publicationDate":"1997-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21254349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A new variety of Chainia olivacea from marine sediment off Gulf of Mannar. 标题马纳尔湾海相沉积物中橄榄藻一新变种。
Hindustan antibiotics bulletin Pub Date : 1997-02-01
P Ellaiah, D Kalyan, V S Rao, B V Rao
{"title":"A new variety of Chainia olivacea from marine sediment off Gulf of Mannar.","authors":"P Ellaiah,&nbsp;D Kalyan,&nbsp;V S Rao,&nbsp;B V Rao","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A new variety of Chainia olivacea was isolated from marine sediment off Gulf of Mannar. The morphological, cultural, physiological and biochemical characters were studied, compared to known species and identified as a new variety of Chainia olivacea. Antibiotic activity of the strain was tested against both Gram positive and Gram negative bacteria as well as fungi and yeasts. Sodium chloride tolerance was also tested.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"39 1-4","pages":"50-5"},"PeriodicalIF":0.0,"publicationDate":"1997-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21254350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In vitro evaluation of inhibitory nature of extracts of 18-plant species of Chhindwara against 3-keratinophilic fungi. 18种钦德瓦拉植物提取物对3-嗜角蛋白真菌的体外抑菌性评价。
Hindustan antibiotics bulletin Pub Date : 1997-02-01
S Qureshi, M K Rai, S C Agrawal
{"title":"In vitro evaluation of inhibitory nature of extracts of 18-plant species of Chhindwara against 3-keratinophilic fungi.","authors":"S Qureshi,&nbsp;M K Rai,&nbsp;S C Agrawal","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Effect of extract of 18 plant species, viz., Acorus calamus, Adhatoda vasica, Amomum subulatum, Andrographis paniculata, Boerhaavia diffusa, Cassia occidentalis, Centella asiatica, Cymbopogon citratus, Hemidesmus indicus, Hyptis suaveolens, Malvestrum sp., Passiflora edulis, Pergularia daemia, Peristrophe bicalyculata, Shuteria hirsuta, Solanum nigrum, Tecoma stans, and Verbascum chinense on the growth of Microsporum gypseum, Chrysosporium tropicum and Trichophyton terrestre was evaluated and discussed. The sensitivity of the keratinophilic fungi was evaluated by dry-weight method. The maximum inhibition of mycelial growth was shown by M. gypseum (86.62%) followed by T. terrestre (81.86%) and C. tropicum (74.06%) when treated with S. hirsuta whereas the minimum inhibition was exhibited by M. gypseum (0.29%), C. tropicum (0.16%) and T. terrestre (1.76%) when tested with the extract of P. edulis, A. vasica and B. diffusa respectively.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"39 1-4","pages":"56-60"},"PeriodicalIF":0.0,"publicationDate":"1997-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21253649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antimycotic effects of some antibiotics on the growth of some dermatophytes and other keratin degrading fungi. 一些抗生素对一些皮肤真菌和其他角蛋白降解真菌生长的抑菌作用。
Hindustan antibiotics bulletin Pub Date : 1997-02-01
C J Singh, B G Singh
{"title":"Antimycotic effects of some antibiotics on the growth of some dermatophytes and other keratin degrading fungi.","authors":"C J Singh,&nbsp;B G Singh","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Four antibiotics have been tested against the growth of some dermatophytes and keratin degrading fungi. A gradual decrease in growth was observed with increase in concentration of all antibiotics. All, but griseofulvin observed to inhibit > 50% mycelial weight even at a lower concentration of 50 ppm. Azole derivatives were most toxic to the growth of M. gypseum at all concentrations, whereas, to that of C. tropicum at above 100 ppm. Mycostatin was the most toxic antibiotic to the growth of M. gypsea at all concentrations.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"39 1-4","pages":"61-3"},"PeriodicalIF":0.0,"publicationDate":"1997-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21253651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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