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Hepatoprotective effect of rhinax on antitubercular drug-induced hepato-toxicity in rats. 鼻屎对抗结核药物致大鼠肝毒性的保护作用。
Hindustan antibiotics bulletin Pub Date : 2002-02-01
Jayant N Dhuley
{"title":"Hepatoprotective effect of rhinax on antitubercular drug-induced hepato-toxicity in rats.","authors":"Jayant N Dhuley","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Rhinax, a polyherbal formulation, exhibited hepatoprotective function when tested against antitubercular drug-induced hepatotoxicity in rats. Suppression of GSH and antioxidant enzymes \"superoxide dismutase (SOD), catalase (CAT), glutathione reductase (GR), gultathionle peroxidase (GPx) and glutathione S-transferase (GST) were noticed in the liver of antitubercular chemotherapeutic agents (namely isoniazid, rifampicin and pyrazinamide) treated animals accompanied with an increase in cytochrome P-450 contents and increased production of lipid peroxidation. Rhinax afforded hepatoprotection by inhibiting lipid peroxidation and, as a result, the animals showed improved antioxidant status.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"44 1-4","pages":"53-9"},"PeriodicalIF":0.0,"publicationDate":"2002-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24449741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bioactive actinomycetes from Krishna River sediments of Andhra Pradesh. 安得拉邦克里希纳河沉积物中的生物活性放线菌。
Hindustan antibiotics bulletin Pub Date : 2002-02-01
P Ellaiah, K V V S N Bapi Raju, K Adinarayana, G Adinarayana, V Saisha, S Madhavi, J Premkumar
{"title":"Bioactive actinomycetes from Krishna River sediments of Andhra Pradesh.","authors":"P Ellaiah,&nbsp;K V V S N Bapi Raju,&nbsp;K Adinarayana,&nbsp;G Adinarayana,&nbsp;V Saisha,&nbsp;S Madhavi,&nbsp;J Premkumar","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Sediment samples from Krishna River at Nagayalanka of Andhra Pradesh, India were investigated as a source of actinomycetes to screen for the production of novel bioactive compounds. During our investigation on fresh water actinomycetes from 5 different river sediment samples, a total of 80 actinomycetes were isolated. Out of these 80 isolates, 30 isolates which showed distinct macromorphological characteristics were selected. The antimicrobial and enzymatic activities were studied for all the 30 isolates. The preliminary study for antimicrobial activity by cross streak method indicated that 16 isolates (53.3%) have excellent antagonistic properties. All these 16 isolates were subjected to detailed submerged fermentation studies. It was observed that 12 isolates (40.0%) exhibited antibacterial activity, 9 isolates (30.0%) showed antifungal activity while 5 isolates (16.6%) showed both antibacterial and antifungal activities. All the 30 isolates were also subjected for the determination of enzymatic activities 25 isolates (83.3%) exhibited amylolytic activity while 27 isolates (90.0%) showed proteolytic activity. Among these isolates, six promising isolates were selected for detailed morphological, cultural, physiological and biochemical studies. It was established that these isolates belong to the Streptomyces genus by virtue of their cell wall composition pattern and were identified as strains of different Streptomyces species like S. rochei, S. alanosinicus, S. erumpens, S. griseoplanus, S. gancidicus and S. nigrogriseolus.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"44 1-4","pages":"8-16"},"PeriodicalIF":0.0,"publicationDate":"2002-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24449828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dr. M.J. Thirumalachar, (1914-1999)- an obituary and bibliography. M.J. Thirumalachar博士(1914-1999)-讣告和参考书目。
Hindustan antibiotics bulletin Pub Date : 2000-01-01
R K Nanda, A R Jadhav
{"title":"Dr. M.J. Thirumalachar, (1914-1999)- an obituary and bibliography.","authors":"R K Nanda,&nbsp;A R Jadhav","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"42-43 ","pages":"1-17"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24447142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hindustan Antibiotics Bulletin, Cumulative Indexes, vol. 1-41, 1958-1999. 印度斯坦抗生素公报，累积指数，卷1- 41,1958 -1999。
Hindustan antibiotics bulletin Pub Date : 2000-01-01
A R Jadhav
{"title":"Hindustan Antibiotics Bulletin, Cumulative Indexes, vol. 1-41, 1958-1999.","authors":"A R Jadhav","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"42-43 ","pages":"18-64"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24444218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ELISA using enzyme penicillinase for the detection of IgG antibodies to Trypanosoma evansi in sera of experimentally infected rabbits. ELISA法采用青霉酶检测实验感染家兔血清中伊文氏锥虫IgG抗体。
Hindustan antibiotics bulletin Pub Date : 1998-02-01
G M Bhopale, S R Naik
{"title":"ELISA using enzyme penicillinase for the detection of IgG antibodies to Trypanosoma evansi in sera of experimentally infected rabbits.","authors":"G M Bhopale,&nbsp;S R Naik","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An Enzyme Linked Immunosorbent Assay (ELISA) using penicillinase as an enzyme marker has been developed for the detection of IgG antibodies in the sera of Trypanosoma evansi infected rabbits. Anti-T. evansi IgG antibodies were detected on 10th day after the infection and thereafter antibody titre rose progressively for 18 days. The developed assay is simple (end result assessed visually) and reproducible (4.4 and 14.0 percentage of intra and inter coefficient of variation respectively).</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"40 1-4","pages":"47-50"},"PeriodicalIF":0.0,"publicationDate":"1998-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26244223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Seed borne nature of Azotobacter chroococcum in chilli (Capsicum annum) and its role in seed germination and plant growth. 辣椒(Capsicum annum)中嗜铬固氮菌的传种性质及其在种子萌发和植株生长中的作用。
Hindustan antibiotics bulletin Pub Date : 1998-02-01
J M Bhat, A R Alagawadi
{"title":"Seed borne nature of Azotobacter chroococcum in chilli (Capsicum annum) and its role in seed germination and plant growth.","authors":"J M Bhat,&nbsp;A R Alagawadi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Investigations were carried out on seed borne nature of Azotobacter chroococcum in chilli and their role in plant growth at the Department of Agriculture Microbiology, University of Agricultural Sciences, Dharwad. Azotobacter chroococcum were isolated from both surface sterilized and unsterilized seeds of 14 varieties of chilli at different stages of fruit maturity. Inoculation with these strains increased the seed germination, root, shoot length and total dry matter content of chilli plants significantly in both sterilized and unsterilized soil., the results of which are presented.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"40 1-4","pages":"20-30"},"PeriodicalIF":0.0,"publicationDate":"1998-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26244338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exopolysaccharide production by some rhizobium strain in culture. 某些根瘤菌在培养过程中的胞外多糖产量。
Hindustan antibiotics bulletin Pub Date : 1998-02-01
P Ray, S Pal, A K Paul
{"title":"Exopolysaccharide production by some rhizobium strain in culture.","authors":"P Ray,&nbsp;S Pal,&nbsp;A K Paul","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Eight Rhizobium strains were screened for exopolysaccharide production during growth in yeast extract mannitol medium. A strain of Rhizobium loti produced more than 250 mg of exopolysaccharide/100 ml of culture during the stationary phase of growth. Exopolysaccharide production was favoured by maltose and mannitol but N2 supplementation could not affect the production siginificantly. Preliminary studies indicate that the polymer contains 16% protein and 73.5% carbohydrate being composed of glucose, galactose and glucuronic acid.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"40 1-4","pages":"42-6"},"PeriodicalIF":0.0,"publicationDate":"1998-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26244343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preliminary studies on production of extracellular lipase by an isolate from soil : Aspergillus flavus oryzae. 土壤中分离物米黄曲霉生产胞外脂肪酶的初步研究。
Hindustan antibiotics bulletin Pub Date : 1998-02-01
A G Venkatesh, R G Muley, S R Naik
{"title":"Preliminary studies on production of extracellular lipase by an isolate from soil : Aspergillus flavus oryzae.","authors":"A G Venkatesh,&nbsp;R G Muley,&nbsp;S R Naik","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In our routine screening programme, using agar diffusion assay method, lipolytic activity was detected around a colony of a fungus. The fungus was isolated from a soil sample which was brought from a location near oil-mill. This lipolytic fungus was then identified to belong to Aspergillus flavus oryzae. A medium was then formulated and optimized which would not only support good growth but also would yield good extracellular lipolytic activity. It was observed that a conventional carbohydrate-protein containing medium supported good growth of the fungus but moderate lipase activity, whereas, a hydrocarbon containing medium, although supported relatively less growth, yielded much more lipase activity.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"40 1-4","pages":"14-9"},"PeriodicalIF":0.0,"publicationDate":"1998-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26244337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Population dynamics of antibiotic producing actinomycetes from Avadh soils of U. P., India. 印度联合王国阿瓦德土壤中产抗生素放线菌的种群动态。
Hindustan antibiotics bulletin Pub Date : 1998-02-01
J S Soni, R Gaur, N S Darmwal
{"title":"Population dynamics of antibiotic producing actinomycetes from Avadh soils of U. P., India.","authors":"J S Soni,&nbsp;R Gaur,&nbsp;N S Darmwal","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"40 1-4","pages":"54-8"},"PeriodicalIF":0.0,"publicationDate":"1998-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26244346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimisation of nutritional requirements and process control parameters for the production of HA-2-91, a new tetraene polyene antibiotic. 新型四烯多烯抗生素HA-2-91的营养需求及工艺控制参数优化。
Hindustan antibiotics bulletin Pub Date : 1998-02-01
T E Gupte, S R Naik
{"title":"Optimisation of nutritional requirements and process control parameters for the production of HA-2-91, a new tetraene polyene antibiotic.","authors":"T E Gupte,&nbsp;S R Naik","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>HA-2-91, a new tetraene polyene antibiotic produced during submerged fermentation of Streptomyces arenae var ukrainiana. Optimisation of nutritional requirements and process control parameters were studied for higher productivity of HA-2-91 during fermentative production in shaken flasks using complex media. Experimental findings indicate that jowar starch (Sorghum vulgare) is the best carbon source while cornsteep liquor in combination with peanut meal are the best nitrogen sources. Exogenous addition of amino acids, divalent cations and fatty acids suppressed the productivity of HA-2-91. Incorporation of glucose into the production medium above 5% (w/v) results in inhibition of productivity of HA-2-91 which may be due to catabolite regulation. The concentration of phosphate ions above 10 ppm also showed similar suppression effect on the productivity of HA-2-91. However, ferrous ions at 100 ppm showed slight stimulatory effect on the production of HA-2-91. The optimum process control parameters for the production of HA-2-91 were found to be temperature, 28 degrees C; inoculum concentration from seed to production medium, 1% (v/v); pH and volume of production medium 6.5 and 100 ml respectively; and fermentation cycle time, 120 hours.</p>","PeriodicalId":12923,"journal":{"name":"Hindustan antibiotics bulletin","volume":"40 1-4","pages":"5-13"},"PeriodicalIF":0.0,"publicationDate":"1998-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26244336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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