Green Synthesis and Catalysis最新文献_第3页

Chemo- and diastereoselective four-component reactions with Rh carbynoids Rh类碳的化学和非对映选择性四组分反应

Green Synthesis and Catalysis Pub Date : 2025-02-01 DOI: 10.1016/j.gresc.2024.10.006

Mengchu Zhang , Xiaoyan Yang , Xiang Fu , Xiaoyu Zhou , Yu Qian , Wenhao Hu

{"title":"Chemo- and diastereoselective four-component reactions with Rh carbynoids","authors":"Mengchu Zhang , Xiaoyan Yang , Xiang Fu , Xiaoyu Zhou , Yu Qian , Wenhao Hu","doi":"10.1016/j.gresc.2024.10.006","DOIUrl":"10.1016/j.gresc.2024.10.006","url":null,"abstract":"<div><div>Multi-component reactions (MCRs) provide an efficient method for constructing multiple chemical bonds by combining three or more starting materials in a single operational step, enabling rapid and cost-effective synthesis of structurally diverse compounds. Although carbynoids (R-C:+) have shown potential for the development of selective MCRs due to their unique carbene and carbocation characteristics, their application in four-component reactions (4CRs) has been constrained by challenges in chemoselectivity. Herein, we provide a general solution to the challenges of chemoselective 4CR, using halo diazo reagents as carbynoid precursors, followed by reacting with pyrazoles, alcohols and imines sequentially. This approach allows the simultaneous construction of three different <em>C</em> (<em>sp</em><sup><em>3</em></sup>)-<em>N</em>, <em>C</em> (<em>sp</em><sup><em>3</em></sup>)-<em>O</em>, and <em>C</em> (<em>sp</em><sup><em>3</em></sup>)-<em>C</em> (<em>sp</em><sup><em>3</em></sup>) bonds on the same carbon. The success of this protocol mainly depends on precise control of chemical kinetics. Detailed experimental studies elucidate that the generation rate of <em>aza</em>-Rh(II)-carbene is faster than <em>oxy</em>-Rh(II)-carbene.</div></div>","PeriodicalId":12794,"journal":{"name":"Green Synthesis and Catalysis","volume":"6 1","pages":"Pages 101-105"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143507929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sustainable synthetic routes to deuterium-labelled organic compounds using immobilized and recyclable (bio)catalysts 可持续合成路线，以氘标记的有机化合物使用固定化和可回收（生物）催化剂

Green Synthesis and Catalysis Pub Date : 2025-02-01 DOI: 10.1016/j.gresc.2024.09.008

Luka Jedlovčnik , Jakob Höfferle , Aljaž Gaber , Fjoralb Pashaj , Jerneja Kladnik , Janez Košmrlj , Volker Derdau , Ross D. Jansen-van Vuuren

{"title":"Sustainable synthetic routes to deuterium-labelled organic compounds using immobilized and recyclable (bio)catalysts","authors":"Luka Jedlovčnik , Jakob Höfferle , Aljaž Gaber , Fjoralb Pashaj , Jerneja Kladnik , Janez Košmrlj , Volker Derdau , Ross D. Jansen-van Vuuren","doi":"10.1016/j.gresc.2024.09.008","DOIUrl":"10.1016/j.gresc.2024.09.008","url":null,"abstract":"<div><div>Deuterium(D)-labelled organic compounds are used in many applications <em>e.g</em>., as therapeutic agents, internal standards in drug discovery and development, and new functional materials including dyes, catalysts, and light emitters. Conventionally, the synthesis of D-labelled compounds relies on (bio)catalysts due to their regio- and stereoselectivity, mild reaction conditions, and treatment of a broad scope of substrates. However, most (bio)catalysts are expensive to prepare/isolate, and some contain precious metals (PMs), <em>e.g.</em>, Ir, Pd, whose markets are unpredictable, and which need to be separated from the products at great expense, post-reaction. With the general shift away from traditional ‘make-use-dispose’ approaches to ones that are less wasteful, the use of recyclable catalysts in both batch and continuous flow systems are increasingly employed. In this work, we comprehensively and critically review the catalysts and immobilization and recycling strategies implemented for the preparation of D-labelled organic compounds. Our aim is to highlight the most effective advances and expose the gaps in the literature to inform future research.</div></div>","PeriodicalId":12794,"journal":{"name":"Green Synthesis and Catalysis","volume":"6 1","pages":"Pages 1-35"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143508072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Light-induced perfluoroalkylative carbonylation of unactivated alkenes with a recyclable photocatalyst 利用可回收光催化剂对未活化烯烃进行光诱导全氟烷基羰基化反应

Green Synthesis and Catalysis Pub Date : 2025-02-01 DOI: 10.1016/j.gresc.2024.05.002

Heng Yang , Shuyu Yang , Xiao-Feng Wu , Feng Chen

引用次数: 0

Sulfone as traceless activating group: Divergent synthesis of α-fluoroamides with C–F quaternary stereocenters 作为无迹激活基团的砜：含C-F季立体中心的α-氟酰胺的发散合成

Green Synthesis and Catalysis Pub Date : 2025-02-01 DOI: 10.1016/j.gresc.2024.09.006

Jieqing Wu , Liying Fu , Renyi Diao , Longjun Nie , Chi Zhang , Yufeng Li , Chao Feng

引用次数: 0

One-pot access to indazole fused-phenanthridinones via Rh(III)-catalyzed [4+2] annulation 通过Rh（III）催化[4+2]环法制备茚唑-菲并啶酮

Green Synthesis and Catalysis Pub Date : 2025-02-01 DOI: 10.1016/j.gresc.2023.09.003

Shumin Li, Jinke Chang, Jian Shen, Xiuling Cui

引用次数: 0

Advanced green synthesis: Solvent-free and catalyst-free reaction 先进的绿色合成：无溶剂、无催化剂反应

Green Synthesis and Catalysis Pub Date : 2025-02-01 DOI: 10.1016/j.gresc.2024.11.001

Meng-Yao Li , Ao Gu , Jiatong Li , Yingbin Liu

引用次数: 0

Visible-light-induced reusable decatungstate-photocatalyzed radical cascade alkylation/cyclization of isocyanides with simple alkanes, ethers and ketones 可见光诱导的可重复使用的十钨酸盐光催化自由基级联烷基化/异氰酸酯与简单烷烃、醚和酮的环化反应

Green Synthesis and Catalysis Pub Date : 2025-02-01 DOI: 10.1016/j.gresc.2024.01.003

Ke-Li Wang, Hong-Tao Ji, Qiong-Hui Peng, Jun Jiang, Li-Juan Ou, Wei-Min He

引用次数: 0

Development of a more efficient catalyst for the redox-neutral organocatalytic mitsunobu reaction by DFT-guided catalyst design 采用dft导向设计一种更高效的氧化还原-中性有机催化mitsunobu反应催化剂

Green Synthesis and Catalysis Pub Date : 2024-11-01 DOI: 10.1016/j.gresc.2023.11.002

Dingguo Song , Changjun Zhang , Yuqi Cheng , Linlin Chen, Jie Lin, Changdi Zheng, Ting Liu, Yuxin Ding, Fei Ling, Weihui Zhong

{"title":"Development of a more efficient catalyst for the redox-neutral organocatalytic mitsunobu reaction by DFT-guided catalyst design","authors":"Dingguo Song , Changjun Zhang , Yuqi Cheng , Linlin Chen, Jie Lin, Changdi Zheng, Ting Liu, Yuxin Ding, Fei Ling, Weihui Zhong","doi":"10.1016/j.gresc.2023.11.002","DOIUrl":"10.1016/j.gresc.2023.11.002","url":null,"abstract":"<div><div>The study of a Mitsunobu reaction is an important topic. Denton and co-workers first reported a novel (2-hydroxybenzyl)diphenylphosphine oxide for realizing the catalytic Mitsunobu reaction <em>via</em> a five-membered phosphonium species. However, it is still worth investigating how to improve catalysts with higher efficiency. Guided by computational and experimental studies, we designed a new type of biphenyl-based phosphine oxide that would form a six-membered phosphonium species as a key intermediate to trigger the catalytic Mitsunobu reaction with a lower barrier of the rate-determining step (30.3 kcal/mol). DFT calculations revealed that only trans dehydration was participated in our catalytic progress and a strong <em>π</em>-<em>π</em> interaction and small spatial constraint of <strong>TS-V</strong> were crucial for high behavior. This readily accessible, highly stable, easily recyclable and efficient catalyst would boost the catalytic Mitsunobu reaction.</div></div>","PeriodicalId":12794,"journal":{"name":"Green Synthesis and Catalysis","volume":"5 4","pages":"Pages 290-296"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135715435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pictet-spengler/transamination cascade reaction of indoles for modular synthesis of marinoquinoline analogues 喹啉类似物模块化合成中吲哚的Pictet-spengler/转氨化级联反应

Green Synthesis and Catalysis Pub Date : 2024-11-01 DOI: 10.1016/j.gresc.2023.09.002

Jinjin Chen , Pingyu Jiang , Xinping Liu , Huawen Huang , Guojiang Mao , Guo-Jun Deng

引用次数: 0

Recent advances in (4 + 3) cycloaddition of allenes 烯类化合物(4 + 3)环加成的研究进展

Green Synthesis and Catalysis Pub Date : 2024-11-01 DOI: 10.1016/j.gresc.2023.11.010

Yanyan Que , Wenli Lei , Yin Fang , Shuzhong He , Yang Chen

引用次数: 0