Gland surgery最新文献

{"title":"Feasibility and outcomes of remote-access endoscopic and robotic lateral neck dissection for thyroid cancer: a scoping review.","authors":"Junyi Wang, Yan Zhang, Xiangqian Zheng, Kyung Tae","doi":"10.21037/gs-2024-535","DOIUrl":"https://doi.org/10.21037/gs-2024-535","url":null,"abstract":"<p><strong>Background: </strong>Remote-access endoscopic and robotic thyroid surgery has progressively evolved over the decades to minimize visible neck scarring. Various approaches, including axillary, anterior chest, breast, postauricular, and transoral routes, have been developed, extending their application to lateral neck dissection (LND) in thyroid cancer. This study aims to comprehensively review and synthesize recent literature on remote-access endoscopic and robotic techniques for LND, with a focus on outcomes, advantages, and limitations.</p><p><strong>Methods: </strong>A systematic literature review was conducted using PubMed and Cochrane Library databases. Search terms included \"lateral neck dissection\", \"thyroid cancer\", \"remote-access\", \"robotic\", \"endoscopic\", and \"video-assisted\". Eligible studies were analyzed to provide an in-depth overview of current techniques, addressing the following aspects: (I) incision location; (II) surgical procedures; (III) complications and surgical outcomes; and (IV) advantages and limitations of each approach.</p><p><strong>Results: </strong>Various remote-access techniques for LND were identified, including gasless infraclavicular, breast-chest, gasless transaxillary, bilateral axillo-breast, gasless retroauricular, transoral, and combined approaches. Outcomes, including the number of removed lateral lymph nodes, complication rates, and recurrence rates, were comparable across remote-access approaches. The extent of dissection achieved with these techniques was equivalent to conventional approaches for levels IIa, III, IV, and V, except for the transoral approach, which was generally limited to levels III and IV. Postoperative cosmetic outcomes were significantly superior with remote-access techniques.</p><p><strong>Conclusions: </strong>Remote-access approaches for thyroidectomy combined with LND are both feasible and safe, achieving complete resection of targeted neck levels with excellent surgical and cosmetic outcomes. The unique advantages and limitations of each method underscore the importance of careful patient selection to optimize clinical benefits.</p>","PeriodicalId":12760,"journal":{"name":"Gland surgery","volume":"14 3","pages":"543-562"},"PeriodicalIF":1.5,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12004302/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144013720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative localization of single gland disease in primary hyperparathyroidism: a comparative study for preoperative localization with four-dimensional computed tomography, ultrasonography, and technetium-99m-sestamibi single-photon emission computed tomography.","authors":"Ha-Nee Kwon, Hyeon-Su Kim, Sung-Chan Shin, Yong-Il Cheon, Bo Hyun Kim, Yun Kyung Jeon, Mijin Kim, Keunyoung Kim, Lee Hwangbo, Byung-Joo Lee","doi":"10.21037/gs-2024-482","DOIUrl":"https://doi.org/10.21037/gs-2024-482","url":null,"abstract":"<p><strong>Background: </strong>Treatment guidelines for primary hyperparathyroidism (PHPT) recommend high-resolution neck ultrasonography (US), technetium-99m-sestamibi single-photon emission computed tomography (^99mTc-sestamibi SPECT), and contrast-enhanced four-dimensional computed tomography (4D CT) as image evaluation methods. This study aimed to compare the sensitivity and accuracy of the three image evaluation methods recommended in the guidelines for patients with PHPT and evaluate the utility of 4D CT for preoperative localization in single gland disease.</p><p><strong>Methods: </strong>A retrospective medical chart review was performed on 41 patients who underwent surgery for single gland disease at the Department of Otorhinolaryngology, Pusan National University Hospital, between January 2021 and March 2023. All the patients underwent preoperative US, ^99mTc-sestamibi SPECT, and 4D CT. The location of the abnormal parathyroid lesion, removed during surgery and confirmed by postoperative pathological examination, was used as the reference standard. The sensitivity, specificity, and accuracy of the three imaging evaluations were assessed and compared to the reference standard location.</p><p><strong>Results: </strong>The sensitivity, specificity, and accuracy of the imaging modalities were as follows: 4D CT, 95.1%, 98.4%, and 97.6%; US, 82.9%, 95.1%, and 92.1%; and ^99mTc-sestamibi SPECT, 78.0%, 97.6%, and 92.7%, respectively. Furthermore, a total of nine cases were identified where accurate localization could not be achieved through US and ^99mTc-sestamibi SPECT. The presence of coexisting thyroid lesions was significantly correlated with incorrect localization in preoperative US (P<0.05). The small volume of the parathyroid tumor was significantly associated with an increased rate of false-negatives using ^99mTc-sestamibi SPECT (P<0.05).</p><p><strong>Conclusions: </strong>In the preoperative localization of abnormal parathyroid lesions, 4D CT demonstrated higher sensitivity and specificity than US and ^99mTc-sestamibi SPECT. 4D CT can accurately localize abnormal parathyroid lesions, even in cases in which both US and ^99mTc-sestamibi SPECT yielded incorrect localizations.</p>","PeriodicalId":12760,"journal":{"name":"Gland surgery","volume":"14 3","pages":"305-316"},"PeriodicalIF":1.5,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12004329/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143993246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nomogram to predict late extraluminal postpancreatectomy hemorrhage in patients with postoperative pancreatic fistula after pancreaticoduodenectomy.","authors":"Yichen Li, Haoqi Zhang, Jun Gong, Yue Jian, Siyu Li, Yuxin Yang, Zhenjiang Zheng, Yonghua Chen, Xing Wang, Xubao Liu, Shanmiao Gou, Chunlu Tan","doi":"10.21037/gs-24-412","DOIUrl":"https://doi.org/10.21037/gs-24-412","url":null,"abstract":"<p><strong>Background: </strong>Late extraluminal postpancreatectomy hemorrhage (LEPPH) is a rare but severe complication of pancreaticoduodenectomy (PD). Current predictors of LEPPH are limited and cannot quantify bleeding risk. As a consequence, establishment of a prediction model of LEPPH is important. This study aims to construct a nomogram combining perioperative factors to predict LEPPH.</p><p><strong>Methods: </strong>A total of 2,924 retrospective and 467 prospective cases undergoing PD, 420 retrospective cases and 131 prospective cases with postoperative pancreatic fistula (POPF) after PD from three centers were included. Three hundred and seventy-one retrospective cases from West China Hospital were divided randomly into the development cohort (n=259) and the internal validation cohort (n=112). Another 180 patients consisting of 49 retrospective and 131 prospective cases from three pancreatic centers were enrolled as the external validation set. A nomogram was established based on the independent risk factors.</p><p><strong>Results: </strong>Multivariable analysis identified pancreaticoenteric anastomotic dorsal fluid accumulation, bubble sign, pancreaticoenteric anastomotic cracking (PEAC), surgery-related acute pancreatitis (AP), and positive culture in intra-abdominal drainage fluid as independent risk factors of LEPPH. Combined with those variables, the nomogram showed reliable C-index of 0.932, 0.924 and 0.954 in predicting LEPPH in the three cohorts respectively.</p><p><strong>Conclusions: </strong>The nomogram exhibited excellent predictive capabilities for LEPPH after PD. It could aid surgeons in early identification of patients prone to LEPPH following PD, enabling timely interventions and improving patient survival.</p>","PeriodicalId":12760,"journal":{"name":"Gland surgery","volume":"14 3","pages":"281-293"},"PeriodicalIF":1.5,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12004331/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144008366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navigating the rare: a case report of intrathyroidal thymic carcinoma.","authors":"Xiuming Wang, Huabin Zhang, Bojuan Wang, Lei Zhang","doi":"10.21037/gs-2024-540","DOIUrl":"https://doi.org/10.21037/gs-2024-540","url":null,"abstract":"<p><strong>Background: </strong>Intrathyroidal thymic carcinoma (ITTC) is an exceedingly rare malignancy of the thyroid, which presents significant diagnostic challenges. ITTC often has nonspecific clinical manifestations and histological features similar to other thyroid neoplasms, making its diagnosis difficult. This rarity and complexity result in a lack of consensus on its diagnostic criteria and management strategies. ITTC typically arises from ectopic thymic tissue, and despite its malignancy, it generally has a relatively favorable prognosis when accurately diagnosed and treated in a timely manner.</p><p><strong>Case description: </strong>This case report discusses a rare instance of ITTC in a 38-year-old male patient who presented with a 2-month history of neck lumps, accompanied by symptoms of neck compression and hoarseness. Clinical imaging, including ultrasound, suggested the possibility of lymphoma due to the appearance of a hypoechoic lesion encasing the carotid artery. However, after conducting immunohistochemical analysis, including markers such as CD5 and CD117, a definitive diagnosis of ITTC was made. The case highlights the diagnostic challenges posed by this rare malignancy and the critical role of histopathology in its identification.</p><p><strong>Conclusions: </strong>ITTC is a rare, low-grade malignant tumor that can often be mistaken for other types of thyroid cancers. Multidisciplinary collaboration is essential for accurate diagnosis and optimal treatment planning. While the diagnosis of ITTC can be complex, immunohistochemical markers are instrumental in confirming the presence of this tumor. Despite its rarity, ITTC generally carries a favorable prognosis, with a 5-year survival rate of approximately 90%. This case report contributes to the limited body of literature on ITTC and underscores the importance of recognizing its unique immunophenotype in achieving an accurate diagnosis.</p>","PeriodicalId":12760,"journal":{"name":"Gland surgery","volume":"14 3","pages":"570-576"},"PeriodicalIF":1.5,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12004328/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and validation of a multidimensional machine learning-based nomogram for predicting central lymph node metastasis in papillary thyroid microcarcinoma.","authors":"Xingqi Liu, Haoyang Li, Lixin Zhang, Qing Gao, Yingfei Wang","doi":"10.21037/gs-2024-508","DOIUrl":"https://doi.org/10.21037/gs-2024-508","url":null,"abstract":"<p><strong>Background: </strong>Papillary thyroid microcarcinoma (PTMC), a subset of papillary thyroid carcinoma (PTC), is characterized by tumors ≤10 mm in size. While generally indolent, central lymph node metastasis (CLNM) is associated with higher risks of recurrence and distant metastasis. Existing prediction models for CLNM predominantly depend on isolated clinical or imaging parameters, failing to integrate multidimensional predictors such as clinicopathological, ultrasonographic, and serological features. This limitation significantly undermines their clinical applicability. Therefore, we developed a machine learning-based nomogram that integrates comprehensive predictors to enhance preoperative risk stratification and facilitate personalized surgical decision-making.</p><p><strong>Methods: </strong>A retrospective study was conducted on 503 PTMC patients who underwent thyroidectomy in Liaoyang Central Hospital between 2020 and 2023. Patients were randomly divided into training (n=352) and validation (n=151) cohorts. Inclusion criteria required preoperative imaging to confirm no cervical lymph node metastasis (LNM), complete clinicopathologic data, and initial surgery with central lymph node dissection, as well as postoperative pathology confirming PTC. Multidimensional predictors (clinical demographics, ultrasonographic features, serological markers, and histopathological characteristics) were analyzed. CLNM was definitively diagnosed via postoperative histopathology. Least absolute shrinkage and selection operator (LASSO) regression was used to identify key predictors, which were incorporated into a logistic regression model. The model's performance was evaluated using receiver operating characteristic (ROC) curves, calibration plots, and decision curve analysis (DCA).</p><p><strong>Results: </strong>Among 503 enrolled patients (mean age: 48.5 years; male: 24%, female: 76%), CLNM was pathology confirmed in 28.8% (145/503). Age, gender, tumor size, tumor location, and extrathyroidal extension (ETE) were identified as independent predictors of CLNM. The nomogram achieved an area under the curve (AUC) of 0.88 (sensitivity 0.84, specificity 0.76) in the training cohort and 0.78 (sensitivity 0.80, specificity 0.70) in the validation cohort. Calibration plots indicated excellent agreement between predicted and observed probabilities, with mean absolute errors below 0.05. DCA demonstrated clinical utility for threshold probabilities ranging from 15% to 88%. These results suggest that the nomogram has good predictive performance and clinical applicability in assessing the risk of CLNM in PTMC patients.</p><p><strong>Conclusions: </strong>This Machine learning-based predictive nomogram provides a reliable tool for assessing CLNM risk in PTMC patients, supporting personalized surgical strategies. Further validation in external cohorts is required to confirm its generalizability.</p>","PeriodicalId":12760,"journal":{"name":"Gland surgery","volume":"14 3","pages":"344-357"},"PeriodicalIF":1.5,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12004296/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143963147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep factors and risk of thyroid cancer, nodules and dysfunction: Mendelian randomization study.","authors":"Yuanyuan Fan, Xun Zheng, Tianfeng Xu, Pengyu Li, Yujie Zhang, Yanhao Ran, Tao Wei","doi":"10.21037/gs-24-435","DOIUrl":"https://doi.org/10.21037/gs-24-435","url":null,"abstract":"<p><strong>Background: </strong>The interplay between sleep physiology and endocrine regulation has been well-established, with the thyroid gland, as a key endocrine organ, demonstrating a physiologically plausible. Previous studies have indicated a potential correlation between sleep factors and thyroid diseases, yet causality remains uncertain. Given the complex interplay of confounders associated with sleep disorders and lifestyle factors, we employed a two-sample Mendelian randomization (MR) approach to minimize confounding bias and rigorously investigate the causal relationship.</p><p><strong>Methods: </strong>The specific information on thyroid diseases-including thyroid cancer, thyroid nodules (TNs), and thyroid dysfunction-was obtained from the FinnGen Biobank using the International Classification of Diseases, 10th Revision (ICD-10). Information on sleep factors such as insomnia symptoms, chronotype, and sleep duration were sourced from genome-wide association studies (GWAS) conducted within the UK Biobank, which provides validated GWAS data through self-report assessment. We employed stringent single nucleotide polymorphisms (SNPs) selection criteria as instrumental variables (IVs) for analyzing sleep factors' causal impact on thyroid diseases. Statistical methods including inverse variance weighted (IVW), weighted median (WM), MR-Egger, and MR-PRESSO were utilized to determine causality, supplemented by F-statistics and sensitivity analyses to ensure robustness and detect biases.</p><p><strong>Results: </strong>The analysis supported that a morning chronotype is protective against thyroid cancer, with results showing a significantly reduced risk [IVW: odds ratio (OR) =0.632, 95% confidence interval (CI): 0.426-0.937, P=0.02]. Conversely, insomnia symptoms were identified as a potential risk factor for developing TNs (IVW: OR =1.973, 95% CI: 1.152-3.377, P=0.01). Sensitivity analyses, including Cochran's <i>Q</i> test, MR-Egger intercept, and MR-PRESSO, showed no significant heterogeneity, horizontal pleiotropy, or outliers (all P values >0.05). However, no significant causal links were found between genetic predispositions to sleep factors and thyroid dysfunction.</p><p><strong>Conclusions: </strong>These findings suggest that therapeutic management of sleep disorders could potentially reduce the risk of developing thyroid diseases, underscoring the importance of routine thyroid monitoring in individuals experiencing sleep disturbances.</p>","PeriodicalId":12760,"journal":{"name":"Gland surgery","volume":"14 3","pages":"368-379"},"PeriodicalIF":1.5,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12004327/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144011072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navigating the complexities of preoperative radiotherapy in breast reconstruction: a new paradigm?","authors":"Justin M Broyles, Jose G Bazan, Ko Un Park","doi":"10.21037/gs-2024-494","DOIUrl":"https://doi.org/10.21037/gs-2024-494","url":null,"abstract":"","PeriodicalId":12760,"journal":{"name":"Gland surgery","volume":"14 3","pages":"272-275"},"PeriodicalIF":1.5,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12004294/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144007659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The predictive value of postoperative intact parathyroid hormone for symptomatic hypocalcemia in older patients with thyroid cancer.","authors":"Lu-Lu Zheng, Ke-Hao Chen, Zhi-Jian Liu, Ling-Hui Dai, Jia-Bo Qin, Yi-Xuan Li, Wen-Xian Guan","doi":"10.21037/gs-2024-526","DOIUrl":"https://doi.org/10.21037/gs-2024-526","url":null,"abstract":"<p><strong>Background: </strong>Due to the unique characteristics of older patients, they are more susceptible to develop symptomatic hypocalcemia (SH). This study aimed to analyze the potential relationship between the occurrence of SH and various indicators in older patients after thyroid cancer surgery, and to further discuss the predictive value of postoperative intact parathyroid hormone (iPTH) for SH, which can provide reference for clinical prevention and treatment of hypocalcemia in older patients.</p><p><strong>Methods: </strong>A total of 137 older patients with thyroid cancer (≥60 years old) admitted to the Department of Thyroid Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School from January 2020 to December 2022 were selected. They were divided into the SH group and the asymptomatic group according to whether they developed SH. Relevant clinical data were collected and retrospectively analyzed. The measurement data of normal distribution were expressed by mean ± standard deviation (SD). Univariate and multivariate analyses were used to determine the risk factors for SH in older patients after thyroid cancer surgery. Statistical significance was set as P<0.05. Receiver operating characteristic (ROC) curve was constructed to study the predictive value of postoperative iPTH for SH occurrence in older patients with thyroid cancer.</p><p><strong>Results: </strong>Among 137 older patients, 48 cases (35.04%) developed SH and 89 cases (64.96%) were asymptomatic. There were significant differences in preoperative iPTH (SH group: 7.00±5.25 pmol/L; asymptomatic group: 5.52±1.80 pmol/L; P=0.004) and postoperative iPTH (SH group: 0.69±0.95 pmol/L; asymptomatic group: 3.30±2.28 pmol/L; P<0.001) between the SH group and the asymptomatic group, with statistical significance (P<0.05). The area under the curve (AUC) of postoperative iPTH predicting SH occurrence in older patients with thyroid cancer was 0.855, cut-off was 0.5941 [95% confidence interval (CI): 0.794-0.917; sensitivity, 87.5%; specificity, 71.9%].</p><p><strong>Conclusions: </strong>Postoperative iPTH is an independent risk factor for predicting SH in older patients with thyroid cancer. In order to avoid the occurrence of postoperative SH and reduce hospitalization costs and length, calcium supplementation should be given as soon as possible according to the level of postoperative iPTH.</p>","PeriodicalId":12760,"journal":{"name":"Gland surgery","volume":"14 3","pages":"510-519"},"PeriodicalIF":1.5,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12004332/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144007718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and validation of a new formula to predict standard pancreas volume in Chinese adults using body surface area.","authors":"Yaping Zhang, Feng Chen, Jiasheng Cao, Domenech Asbun, Kai Siang Chan, Jose M Ramia, Dongju Xiao, Jun Fang, Jiliang Shen","doi":"10.21037/gs-2024-550","DOIUrl":"https://doi.org/10.21037/gs-2024-550","url":null,"abstract":"<p><strong>Background: </strong>Changes in pancreas volume have been reported in many disorders. In clinical practice, pre-disease total pancreas volume (TPV) is often unavailable for patients with pancreatic pathologies (e.g., tumors, cysts, or pancreatitis), as prior imaging may not exist or may reflect abnormal volumes. While three-dimensional (3D) computed tomography (CT) reconstruction provides accurate TPV measurements, its utility is limited in these scenarios, necessitating a predictive formula. However, no widely clinically accepted standard pancreas volume (SPV) formula currently exists. This study aims to develop an SPV prediction formula based on 3D CT reconstruction and the characteristics of Chinese adults.</p><p><strong>Methods: </strong>The TPV of 377 Chinese adults were obtained via CT 3D reconstruction estimation, 287 of whom were used to construct the formula and 90 of whom were used to validate the formula. The associations of age, gender, weight, height, body mass index (BMI), and body surface area (BSA) with TPV were assessed using Pearson correlation analysis. Stepwise multiple linear regression analysis was used to identify the independent correlation factors that could predict TPV.</p><p><strong>Results: </strong>Age, gender, weight, height, BMI, and BSA significantly correlated with TPV. In addition, stepwise multiple linear regression showed that BSA was the only independent correlation factor for TPV. Therefore, BSA was used as the factor in the following formula for calculating SPV: SPV (cm³) = 52.40 × BSA (m²) - 21.33 (R²=0.384).</p><p><strong>Conclusions: </strong>We created a BSA-based formula to predict SPV in Chinese adults. It can be used to evaluate pancreas volume changes in patients with diabetes or other pancreatic diseases.</p>","PeriodicalId":12760,"journal":{"name":"Gland surgery","volume":"14 3","pages":"479-487"},"PeriodicalIF":1.5,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12004316/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144005174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The 100 most-cited articles in thyroid surgery from 1990 to 2023: a bibliometric analysis.","authors":"Donglun Li, Yue Hu, Yingjun Zheng, Lin Chun, Jiayi Song, Caihong Cao, Jianxiong Wang","doi":"10.21037/gs-2024-559","DOIUrl":"https://doi.org/10.21037/gs-2024-559","url":null,"abstract":"<p><strong>Background: </strong>The 2015 U.S. guidelines for the diagnosis and treatment of thyroid nodules are recognized as authoritative in the industry, but lack a comprehensive assessment of the development of this field. The purpose of this bibliometric analysis is to identify and assess the 100 most-cited articles that have shaped the modern history of thyroid surgery.</p><p><strong>Methods: </strong>The Web of Science Core Collection database was used to search the 100 most-cited articles in the field of thyroid surgery. VOSviewer was used to visually analyse countries/regions, institutions, authors, keywords, and characteristics of the top-100 articles.</p><p><strong>Results: </strong>The citations of the 100 most-cited articles published between January 1990 and January 2023 ranged from 279 to 7,073. The 100 most-cited articles were published by 25 countries, over half of which were from the USA (n=54). Harvard University (14 articles) and University System of Ohio (14 articles) from the USA (The United States of America) were the top institutions. Schlumberger M from the Institute Gustave Roussy and University Paris Sud was the most productive author with 10 articles. The top-cited article was published by Haugen Bryan R <i>et al.</i> in <i>Thyroid</i> [2015] (citations =7,073). The keywords with the most co-occurrences were carcinoma, followed by fine-needle-aspiration, management, follow up, biopsy, radioactive iodine, and braf (v600e) mutation.</p><p><strong>Conclusions: </strong>The top 100 articles in thyroid surgery have been cited widely and have had a profound impact. The USA was the most influential and productive country. Harvard University and University System of Ohio contributed most to the top 100 articles. Schlumberger M was the most productive and influential author. Moreover, especially thyroid papillary carcinoma, fine needle aspiration, is a research hotspot and potential direction in the future for thyroid surgery.</p>","PeriodicalId":12760,"journal":{"name":"Gland surgery","volume":"14 3","pages":"498-509"},"PeriodicalIF":1.5,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12004318/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143982884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}