Gaceta medica de Mexico最新文献_第8页

New perspectives in the management of SARS-CoV-2 Pirola variants and the development of long COVID syndrome: anti-Ro52/TRIM21 antibodies and qRT-PC. 抗ro52 /TRIM21抗体和qRT-PC在SARS-CoV-2 pi罗拉变异体治疗和长冠状病毒综合征发展中的新视角

IF 0.6 4区医学

Gaceta medica de Mexico Pub Date : 2024-01-01 DOI: 10.24875/GMM.M24000922

César E Rabadán-Martínez

引用次数: 0

Diabetes and economy, a problem for the population. 糖尿病和经济，是人口的问题。

IF 0.6 4区医学

Gaceta medica de Mexico Pub Date : 2024-01-01 DOI: 10.24875/GMM.M24000929

Henry C Rivas-Sucari

引用次数: 0

Application of the 6-SNP elevated LDL-cholesterol polygenic risk score in individuals with familial hypercholesterolemia phenotype from an Argentine population. 6-SNP升高ldl -胆固醇多基因风险评分在阿根廷人群家族性高胆固醇血症表型个体中的应用

IF 0.6 4区医学

Gaceta medica de Mexico Pub Date : 2024-01-01 DOI: 10.24875/GMM.M24000918

Virginia Bañares, Javier Martini, Graciela López, Pablo Corral, Laura Schreier

{"title":"Application of the 6-SNP elevated LDL-cholesterol polygenic risk score in individuals with familial hypercholesterolemia phenotype from an Argentine population.","authors":"Virginia Bañares, Javier Martini, Graciela López, Pablo Corral, Laura Schreier","doi":"10.24875/GMM.M24000918","DOIUrl":"https://doi.org/10.24875/GMM.M24000918","url":null,"abstract":"Introduction: LDL-cholesterol greater than 190 mg/dL indicates severe hypercholesterolemia (HS) of monogenic and/or polygenic origin. Genetic risk scores (GRS) evaluate potential polygenic causes.Objective: we applied a GRS of 6-SNP (GRS-6) in HS individuals.Material and methods: 69 subjects from the Familial Hypercholesterolemia (HF) Detection registry in Argentina (Da Vinci).Results: with 44 individuals with HF-phenotype, not carriers of genetic variants that indicate a monogenic origin (HF/M-) and 26 controls, the GRS-6 cut-off value was established, > 0.76, sensitivity 0.59, specificity 0.69. 15/44(34 %) HF/M- presented GRS-6+. The mean GRS-6 values in HF/M-, HF/M+ and controls were 0.72 ± 0.17, 0.66 ± 0.17, and 0.70 ± 0.13 respectively (p = 0.43). There were no significant differences in cholesterol values, or in the clinical score, between cases with positive vs negative GRS-6. The GRS-6 was positive in 32 % of the cases vs 20 % of the previously applied GRS-10 (p = 0.003), significantly increasing the detection of polygenic contribution.Conclusions: We present an estimate of the first cut-off value for the GRS-6 in a Latin American population, and we conclude that the GRS-6 could contribute to the evaluation of the polygenic contribution in cases with severe hypercholesterolemia in our population in a similar way to that of other European populations.","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"160 4","pages":"413-419"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143004291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Special issue: aging. 特刊：老龄化。

IF 0.6 4区医学

Gaceta medica de Mexico Pub Date : 2024-01-01 DOI: 10.24875/GMM.M24000893

Carmen García-Peña, Germán E Fajardo-Dolci

引用次数: 0

Concordance of grip strength measurement between a digital handheld dynamometer and a Hydraulic dynamometer. 数字式手持测力计和液压式测力计测量握力的一致性。

IF 0.6 4区医学

Gaceta medica de Mexico Pub Date : 2024-01-01 DOI: 10.24875/GMM.24000109

Amor A Segura-Duarte, Gerardo Méndez-Suárez, Laura P Burgos-Morelos, José J Rivera-Sánchez

{"title":"Concordance of grip strength measurement between a digital handheld dynamometer and a Hydraulic dynamometer.","authors":"Amor A Segura-Duarte, Gerardo Méndez-Suárez, Laura P Burgos-Morelos, José J Rivera-Sánchez","doi":"10.24875/GMM.24000109","DOIUrl":"https://doi.org/10.24875/GMM.24000109","url":null,"abstract":"Background: Assessment of muscle strength is of great interest for the study of age-associated pathologies, including frailty and sarcopenia. However, the cost of some of the equipment necessary for its evaluation could be prohibitive for its generalized use in some settings.Objective: The purpose of the present study was to compare two handheld dynamometers to evaluate the measure of concordance between the measurements. Material and methods The study was conducted in the outpatient Geriatrics clinics where 120 community-dwelling participants aged 60 years and more were evaluated using two devices: the JAMAR® Hydraulic Hand Dynamometer and the digital hand dynamometer CAMRY® EH101.Results: We observed a positive correlation between the two devices for dominant hand (DH) Pearson r 0.974 (p < 0.001) and a Spearman ρ 0.973 (p < 0.001) for non-dominant hand (NDH) Lin's coefficient for the DH was 0.98 (p < 0.001) and for the NDH 0.97 (p < 0.001). The intraclass correlation coefficient was 0.971 (95% CI, 0.95-0.97; p < 0.001) for DH and 0.975 (95% CI, 0.96-0.98; p < 0.001) for NDH.Conclusions: In this study, the Camry dynamometer was observed to be reliable for measuring hand grip strength in community-dwelling people 60 years or older.","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"160 3","pages":"308-312"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142739316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ChatGPT: opportunities, risks, medical care, teaching, and research. ChatGPT：机遇、风险、医疗、教学和研究。

IF 0.6 4区医学

Gaceta medica de Mexico Pub Date : 2024-01-01 DOI: 10.24875/GMM.23000497

Hinpetch Daungsupawong, Viroj Wiwanitkit

引用次数: 0

Clinical-epidemiological characterization of patients with long COVID in Mexico. 墨西哥长程 COVID 患者的临床流行病学特征。

IF 0.6 4区医学

Gaceta medica de Mexico Pub Date : 2024-01-01 DOI: 10.24875/GMM.M24000875

Luis Del Carpio-Orantes, Daniela Trelles-Hernández, Sergio García-Méndez, Jesús S Sánchez-Díaz, Andrés Aguilar-Silva, Ener R López-Vargas

{"title":"Clinical-epidemiological characterization of patients with long COVID in Mexico.","authors":"Luis Del Carpio-Orantes, Daniela Trelles-Hernández, Sergio García-Méndez, Jesús S Sánchez-Díaz, Andrés Aguilar-Silva, Ener R López-Vargas","doi":"10.24875/GMM.M24000875","DOIUrl":"https://doi.org/10.24875/GMM.M24000875","url":null,"abstract":"Background: Long COVID is defined as the persistence of COVID-19 symptoms four weeks after having undergone acute infection, according to the most recent CDC definition. It is estimated that there are 65 million people affected by this entity, although other figures speak of 200 million.Objective: To characterize the population affected by long COVID in Mexico.Material and methods: Patients older than 18 years who agreed to answer an online survey and who met the criteria for long COVID were included.Results: Data from 203 subjects were included, with 138 (68.0%) being found to be females, and average age to be 41.8 years; 29.6% had severe disease, and 70.4%, mild to moderate disease; 89.7% had received prior COVID-19 vaccination: 6.9% had received one dose; 31.5%, two doses; and 51.2%, three or more doses. The main risk factors were diabetes, overweight or obesity, and hypertension. The most commonly reported symptom was fatigue, followed by other neuropsychiatric manifestations.Conclusion: It is important for the population affected by long COVID to be characterized in order to generate diagnostic and treatment protocols.","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"160 2","pages":"136-143"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141906339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of animals for scientific and educational purposes by Mexican institutions. 墨西哥机构为科学和教育目的使用动物。

IF 0.6 4区医学

Gaceta medica de Mexico Pub Date : 2024-01-01 DOI: 10.24875/GMM.24000067

Patricia Frías-Álvarez, Gustavo Ortiz-Millán

引用次数: 0

Prescription of non-steroidal anti-inflammatory and antirheumatic drugs in outpatient hypertensive patients. 门诊高血压患者的非甾体类抗炎药和抗风湿药处方。

IF 0.6 4区医学

Gaceta medica de Mexico Pub Date : 2024-01-01 DOI: 10.24875/GMM.M24000889

Nallely Aguiñaga-Martínez, Juan de Dios Zavala-Rubio, Melissa Ramírez-Ruíz, Alberto J Hernández-Garza, Martín Segura-Chico, Miriam J De la Mata-Márquez, Dolores Mino-León

{"title":"Prescription of non-steroidal anti-inflammatory and antirheumatic drugs in outpatient hypertensive patients.","authors":"Nallely Aguiñaga-Martínez, Juan de Dios Zavala-Rubio, Melissa Ramírez-Ruíz, Alberto J Hernández-Garza, Martín Segura-Chico, Miriam J De la Mata-Márquez, Dolores Mino-León","doi":"10.24875/GMM.M24000889","DOIUrl":"https://doi.org/10.24875/GMM.M24000889","url":null,"abstract":"Background: It has been documented that NSAIDs (nonsteroidal anti-inflammatory and antirheumatic drugs) reduce the effectiveness of some antihypertensive drugs.Objective: Analyze the prescription of NSAID and the variables associated in outpatients with hypertension and explore some characteristics of the physicians.Material and methods: Cross-sectional study, included patients with hypertension from the Family Medicine Unit No. 24 in Mante, Tamaulipas. From the patients, sociodemographic data, clinical history and pharmacological treatments were obtained. From the physicians, sociodemographic and academic information were collected.Results: Mean age of the patients was 63 ± 11 years and 31.7% were prescribed NSAIDs. When compare exposed versus non-exposed to NSAIDs, being in uncontrolled high blood pressure, uncontrolled hypertension, multimorbidity and polypharmacy. The variables associated to the prescription of NSAIDs were: uncontrolled hypertension, multimorbidity and polypharmacy. The 56.7% of the physicians were women, 83.3% with experience >10 years and 33.3% with current certification by the Council in Family Medicine.Conclusions: The inappropriate prescription of NSAIDs revealed the need to implement actions to mitigate the potential risk for the hypertension patients to present a complication.","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"160 2","pages":"154-160"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141909838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efecto del posacondicionamiento isquémico remoto sobre la fracción de eyección del ventrículo izquierdo en pacientes con infarto de miocardio con elevación del segmento ST sometidos a intervención coronaria percutánea primaria 远程缺血性后处理对初次经皮冠状动脉介入治疗ST段抬高心肌梗死患者左心室射血分数的影响

4区医学

Gaceta medica de Mexico Pub Date : 2023-11-02 DOI: 10.24875/gmm.m23000810

Muhammad Fadil, Eryati Darwin, Hirowati Ali, Doni Firman, Muzakkir Amir, Andriany Qanitha

{"title":"Efecto del posacondicionamiento isquémico remoto sobre la fracción de eyección del ventrículo izquierdo en pacientes con infarto de miocardio con elevación del segmento ST sometidos a intervención coronaria percutánea primaria","authors":"Muhammad Fadil, Eryati Darwin, Hirowati Ali, Doni Firman, Muzakkir Amir, Andriany Qanitha","doi":"10.24875/gmm.m23000810","DOIUrl":"https://doi.org/10.24875/gmm.m23000810","url":null,"abstract":"Antecedentes: En los pacientes con infarto agudo de miocardio con elevación del segmento ST (IAMCEST), el acondicionamiento isquémico puede ayudar a limitar la remodelación ventricular. Objetivos: Investigar el efecto del posacondicionamiento isquémico remoto (PAIR) en la función del ventrículo izquierdo durante la intervención coronaria percutánea primaria (ICPP) en pacientes con IAMCEST. Material y métodos: Estudio de intervención pre y posprueba con un total de 60 pacientes con IAMCEST. Los pacientes fueron divididos en dos grupos: con y sin PAIR. Resultados: En el seguimiento de seis meses se observó una diferencia significativa en la fracción de eyección del ventrículo izquierdo en pacientes con ICPP, la cual fue mayor en el grupo con PAIR en comparación con el grupo sin PAIR: 1.0 (−1.0 a 4.3) versus −1.0 (−4.0 a –1.3), p = 0.033. En la medición de seis meses, el volumen sistólico final del ventrículo izquierdo en los pacientes sin PAIR fue mayor en comparación con el grupo homólogo: 79.3 ± 30.5 mL versus 64.4 ± 21.4 mL, p = 0.032. Conclusiones: PAIR muestra efectos favorables en la función ventricular izquierda y, por lo tanto, en el futuro podría ser una estrategia cardioprotectora potencial contra la lesión por isquemia-reperfusión en pacientes con IAMCEST.","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"22 7","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135875173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0