{"title":"Older adults, fragility, care and health.","authors":"José L Rodríguez-Eguizabal","doi":"10.24875/GMM.M25001028","DOIUrl":"https://doi.org/10.24875/GMM.M25001028","url":null,"abstract":"","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"161 3","pages":"322"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145843642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jesús Cajigas-Silva, Jeanette Thorpe, Isobel Spray, Mariusz T Grzeda, Lesly A Portocarrero-Ortiz
{"title":"Adaptation and validation of the Mexican Quality of Life Assessment of Growth Hormone Deficiency in Adults (QoL-AGHDA).","authors":"Jesús Cajigas-Silva, Jeanette Thorpe, Isobel Spray, Mariusz T Grzeda, Lesly A Portocarrero-Ortiz","doi":"10.24875/GMM.24000398","DOIUrl":"https://doi.org/10.24875/GMM.24000398","url":null,"abstract":"<p><strong>Background: </strong>Growth hormone deficiency (GHD), caused by decreased secretion of growth hormone by the pituitary, has clinical repercussions that impact body composition, metabolic parameters, and can have a negative impact on quality of life. The Quality of Life in Adults with Growth Hormone Deficiency (QoL-AGHDA) is a patient-reported outcome measure used to assess the quality of life of adults with GHD.</p><p><strong>Objective: </strong>The objective of this study was to validate the QoL-AGHDA for use in Mexico.</p><p><strong>Materials and methods: </strong>First phase: Translation of the QoL-AGHDA into Spanish as spoken in Mexico. Face and content validity were assessed through 10 Cognitive debriefing interviews. Second phase: The Mexican version of the QoL-AGHDA was administered to 40 patients on two occasions for subsequent analysis. The distributional properties of the measure were explored through descriptive statistics. Cronbach's α was calculated for internal consistency, and Spearman's correlation coefficient was used to assess reliability.</p><p><strong>Results: </strong>The QoL-AGHDA for Mexicans showed high internal consistency, with Cronbach's α coefficients of 0.91 and 0.92. Test-retest reliability was excellent, with a Spearman's correlation coefficient of 0.95.</p><p><strong>Conclusion: </strong>The Mexican adaptation of the QoL-AGHDA demonstrated good psychometric properties, supporting its use in future studies to assess quality of life in adults with GHD in Mexico.</p>","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"161 3","pages":"280-287"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145843702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Artificial intelligence and the metaverse in healthcare.","authors":"Mónica Regalado-Chamorro, Aldo Medina-Gamero","doi":"10.24875/GMM.M26001066","DOIUrl":"https://doi.org/10.24875/GMM.M26001066","url":null,"abstract":"","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"161 4","pages":"435-436"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147467820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Artificial intelligence and immersive reality in the healthcare field.","authors":"Mónica Regalado-Chamorro, Aldo Medina-Gamero","doi":"10.24875/GMM.M25001062","DOIUrl":"https://doi.org/10.24875/GMM.M25001062","url":null,"abstract":"","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"161 4","pages":"434"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147467873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antonio Cortés-Rodríguez, Lisa Alves-Gomes, Marta E Losa-Iglesias, Juan Gómez-Salgado, Ricardo Becerro-de-Bengoa-Vallejo, Miguel A Saavedra-García, Daniel López-López, Ana M Jiménez-Cebrián
{"title":"Repercussion of kinesiophobia in ankylosing spondylitis: a case-control study.","authors":"Antonio Cortés-Rodríguez, Lisa Alves-Gomes, Marta E Losa-Iglesias, Juan Gómez-Salgado, Ricardo Becerro-de-Bengoa-Vallejo, Miguel A Saavedra-García, Daniel López-López, Ana M Jiménez-Cebrián","doi":"10.24875/GMM.25000033","DOIUrl":"10.24875/GMM.25000033","url":null,"abstract":"<p><strong>Background: </strong>Kinesiophobia, or fear of movement, is closely related to ankylosing spondylitis. This fear can make it profoundly difficult to relieve symptoms by discouraging participation in therapeutic exercises.</p><p><strong>Objectives: </strong>The aim of this study was to assess and contrast the perceived levels of safety and confidence during movement tasks.</p><p><strong>Materials and methods: </strong>A total of 104 individuals were recruited. This group was divided into cases and controls, ensuring alignment in terms of age, sex, and body mass index. Demographic information was collected and scores on the Tampa Scale for Kinesiophobia -11 questionnaire were recorded for further comparison.</p><p><strong>Results: </strong>All individuals with Alzheimer's disease (AD) suffered from some degree of kinesiophobia, and 77% had moderate to maximum scores. In contrast, in the control group, without AEs, none presented maximum levels, and 76.9% presented scores with mild or no levels of kinesiophobia. The comparison between groups showed a statistically significant difference.</p><p><strong>Conclusion: </strong>Kinesiophobia was significantly higher in AD patients compared to healthy individuals, emphasizing the need for specific interventions to manage this condition in treatment plans.</p>","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"161 4","pages":"379-384"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147467845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Silvia A Barrera-Barrera, Luis E Fernández-Garza, Miguel Ángel Rodríguez-Weber, Hugo A Barrera-Saldaña
{"title":"Clinical manifestations, laboratory studies, and clinical evolution of newborns with neonatal sepsis treated at a tertiary hospital in Mexico City.","authors":"Silvia A Barrera-Barrera, Luis E Fernández-Garza, Miguel Ángel Rodríguez-Weber, Hugo A Barrera-Saldaña","doi":"10.24875/GMM.24000448","DOIUrl":"10.24875/GMM.24000448","url":null,"abstract":"<p><strong>Background: </strong>Neonatal sepsis is a systemic infection of bacterial, viral, or fungal origin that is associated with hemodynamic changes and other clinical appearances with a positive blood culture in the 1<sup>st</sup> month of life.</p><p><strong>Objective: </strong>To characterize the clinical evolution of neonatal sepsis at a tertiary care hospital in Mexico.</p><p><strong>Material and methods: </strong>Observational, retrospective, and cross-sectional study in Mexico City between 2016 and 2020. The inclusion criteria were patients aged < 28 days and a clinical diagnosis of neonatal sepsis.</p><p><strong>Results: </strong>Ninety-six newborns with suspicion of neonatal sepsis were included, of which 64 (66.7%) were male. The final diagnosis of 58 (60.4%) was early-onset sepsis (EOS), 31 (32.3%) was late-onset sepsis (LOS), 7 (7.9%) were discharged with another diagnosis, and 5 (5.6%) died during hospitalization. Fifteen peripheral blood cultures and five umbilical catheter blood cultures showed growth. The predominance of isolation was Gram-positive, with 65% of these. In the early-onset group, patients were younger, had lower weight, lower APGAR scores, greater need for early neonatal resuscitation, and a higher proportion of a history of maternal infection than in the late-onset group.</p><p><strong>Conclusion: </strong>EOS was more frequent than LOS in a 2:1 ratio, and its overall mortality was 5.2%.</p>","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"161 4","pages":"400-407"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147467857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gloria de L Llamosa-García-Velázquez, Nayeli A Sánchez-Rosales, Francisco A Rodríguez-Leal, Verónica Rivas-Alonso, José de J Flores-Rivera, Francisco J M Mayer-Rivera, Carolina León-Jiménez, Eli Skromne-Eisenberg, Enrique Gómez-Figueroa, Fernanda Flores-Alfaro, Fernando Cortés-Enríquez, Gil Playas-Pérez, Ildefonso Rodríguez-Leyva, Irene Treviño Frenk, Jair F Ortiz-Maldonado, Laura Ordoñez-Boschetti, Leticia Munive-Báez, Lilia Núñez-Orozco, Ma de la Luz Villalpando-Gueich, Ma de la Merced Velázquez-Quintana, Miguel A Macías-Islas, Raúl A Castillo-Lara, Roberto Rodríguez-Rivas, Sandra Quiñones-Aguilar, Sergio Saldívar-Dávila
{"title":"MEXCTRIMS clinical practice guideline for the diagnosis and treatment of multiple sclerosis in Mexico. Part I.","authors":"Gloria de L Llamosa-García-Velázquez, Nayeli A Sánchez-Rosales, Francisco A Rodríguez-Leal, Verónica Rivas-Alonso, José de J Flores-Rivera, Francisco J M Mayer-Rivera, Carolina León-Jiménez, Eli Skromne-Eisenberg, Enrique Gómez-Figueroa, Fernanda Flores-Alfaro, Fernando Cortés-Enríquez, Gil Playas-Pérez, Ildefonso Rodríguez-Leyva, Irene Treviño Frenk, Jair F Ortiz-Maldonado, Laura Ordoñez-Boschetti, Leticia Munive-Báez, Lilia Núñez-Orozco, Ma de la Luz Villalpando-Gueich, Ma de la Merced Velázquez-Quintana, Miguel A Macías-Islas, Raúl A Castillo-Lara, Roberto Rodríguez-Rivas, Sandra Quiñones-Aguilar, Sergio Saldívar-Dávila","doi":"10.24875/GMM.M26001077","DOIUrl":"10.24875/GMM.M26001077","url":null,"abstract":"<p><p>International clinical guidelines aimed at improving the management of multiple sclerosis are difficult to apply to the Mexican health system. This guideline, developed by a group of expert neurologists, members of the Mexican Committee for the Treat-ment and Research in Multiple Sclerosis (MEXCTRIMS), aims to standardize the criteria for diagnosis and treatment of multiple sclerosis in Mexico, adapting them to particular characteristics of the Mexican health system, to offer the neurologist an agile and useful reference tool, applicable to each setting.</p>","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"161 6","pages":"622-630"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148669274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Alpha-lipoic acid prevents ethyl alcohol-induced apoptosis and oxidative stress in kidneys.","authors":"Feyzullah Uçmak, Eda Yildizhan","doi":"10.24875/GMM.25000167","DOIUrl":"https://doi.org/10.24875/GMM.25000167","url":null,"abstract":"<p><strong>Background: </strong>Our aim was to investigate the therapeutic efficacy of alpha-lipoic acid (ALA) against ethyl alcohol (EA)-induced oxidative stress and apoptotic pathways in the kidneys based on biochemical, histopathological, and apoptotic analysis.</p><p><strong>Materials and methods: </strong>Twenty-eight Wistar albino rats were randomly divided into four equal groups. Group I (Sham group): 1 cc saline daily; Group II (ALA): 100 mg/kg/dose/day; Group III (EA group): 5 g/kg/day; Group IV (EA + ALA group): both ALA and EA were administered orally with a gastric catheter simultaneously.</p><p><strong>Results: </strong>In the EA group, malondialdehyde and total oxidant status levels increased, while superoxide dismutase and catalase levels decreased significantly (p = 0.002). However, oxidant levels were significantly stabilized with ALA administration. Furthermore, apoptotic signals such as Bax and Apoptotic peptidase activating factor-1 (APAF-1) were increased in the EA group, while Bcl-2 (antiapoptotic) signals were widely expressed with ALA administration.</p><p><strong>Conclusion: </strong>Co-administration of ALA with EA increased antiapoptotic expression and attenuated histologic damage in the kidneys. ALA may be a potential therapeutic agent against EA injury.</p>","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"161 6","pages":"569-577"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148669318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
María C Cortés-Benavides, Carmen Zavala-García, Carlos A Rivero-López, Juan A Trejo-Mejía, Amílcar Alpuche-Hernández, Carlos de la Torre-González, Adrián Martínez-González
{"title":"Clinical competence level in otoscopy and management of otitis media assessed through an objective structured clinical examination in pediatrics.","authors":"María C Cortés-Benavides, Carmen Zavala-García, Carlos A Rivero-López, Juan A Trejo-Mejía, Amílcar Alpuche-Hernández, Carlos de la Torre-González, Adrián Martínez-González","doi":"10.24875/GMM.M25001092","DOIUrl":"10.24875/GMM.M25001092","url":null,"abstract":"<p><strong>Background: </strong>During professional training, the acquisition of otoscopic skills necessary for accurate diagnosis of ear pathology is often assumed. Studies have reported challenges residents face in mastering this skill.</p><p><strong>Objective: </strong>To assess and compare the level of clinical competence between first-year and third-year pediatric residents in otoscopic skills, and their performance in the diagnosis and management of otitis media, through using an objective structured clinical examination.</p><p><strong>Material and methods: </strong>This was a cross-sectional, observational study. Pediatric residents at the Dr. Federico Gómez Children's Hospital of Mexico were recruited. A 7-station objective structured clinical examination was designed, allotting 10 minutes for each station and 5 minutes for feedback. Independent sample Student's t-test and ANOVA were performed to analyze changes in clinical competence and its attributes.</p><p><strong>Results: </strong>A total of 56 pediatric residents participated, including 27 first-year residents (48.2%) and 29 third-year residents (51.7%). Third-year residents demonstrated higher skills in attributes such as follow-up planning, diagnostic reasoning, patient history-taking, and overall otorhinolaryngology clinical competence.</p><p><strong>Conclusions: </strong>Third-year pediatric residents exhibit a higher level of clinical competence compared to first-year residents.</p>","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"161 5","pages":"495-500"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148535722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrés Castillejo-Del-Río, Javier Fagundo-Rivera, Nadine Badillo-Sánchez, Juan Gómez-Salgado
{"title":"Caring for nurses: a pillar of global health care and promotion.","authors":"Andrés Castillejo-Del-Río, Javier Fagundo-Rivera, Nadine Badillo-Sánchez, Juan Gómez-Salgado","doi":"10.24875/GMM.M25001097","DOIUrl":"https://doi.org/10.24875/GMM.M25001097","url":null,"abstract":"","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"161 5","pages":"547-548"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148535719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}