Ginekologia polska最新文献_第7页

Could pelvic floor sonography be a standalone method for excluding genuine stress urinary incontinence in women? 盆底超声能作为排除女性压力性尿失禁的独立方法吗?

IF 1.3 4区医学

Ginekologia polska Pub Date : 2023-03-17 DOI: 10.5603/GP.a2023.0026

Mariusz Malmur, Jakub Mlodawski, Marta Mlodawska, Marcin Misiek, Olga Adamczyk-Gruszka, Piotr Niziurski, Stanislaw Gluszek, Wojciech Rokita

{"title":"Could pelvic floor sonography be a standalone method for excluding genuine stress urinary incontinence in women?","authors":"Mariusz Malmur, Jakub Mlodawski, Marta Mlodawska, Marcin Misiek, Olga Adamczyk-Gruszka, Piotr Niziurski, Stanislaw Gluszek, Wojciech Rokita","doi":"10.5603/GP.a2023.0026","DOIUrl":"https://doi.org/10.5603/GP.a2023.0026","url":null,"abstract":"Objectives: Determine whether introital pelvic floor sonography with transvaginal probe (PFS-TV) can be an independent method in the diagnosis of genuine stress urinary incontinence (SUI) and to create a ultrasonographic diagnostic model to objectify diagnostic process.Material and methods: The study involved 315 patients with a history of urinary incontinence problems. Based on the clinical examination and urodynamic examination, the final diagnosis was made. Patients were divided into two groups. Group I included women with SUI and Group II included patients without SUI (OAB and no-UI). Each patient underwent PFS-TV at rest and during straining. The groups were compared in terms of ultrasound parameters.Results: Patients from both groups differed statistically in a significant way (p < 0.05) in terms of mean distance between the lower edge of the pubic symphysis at rest 19 mm vs 22 mm (Group I vs Group II) and during straining (D1 and D2) 22 mm vs 26 mm, the average value of the γ angle (at rest (γ1) 37.5° vs 40° and during straining (γ2) and 66° vs 58.5°, average difference value of angle γ during straining and at rest (γ2-γ1) 29° vs 14°, and frequency of urethral funneling 89% vs 17%. Two parameters studied during PFS-TV were included in the logistic regression model used to exclude the stress component of urinary incontinence. Diagnostic test parameters of model were sensitivity 86.6%, specificity 90.4%, accuracy 93.1%.Conclusions: PFS-TV makes it possible to exclude the stress component of urinary incontinence. The developed logistic regression model allows for the objectification of the results of ultrasound examination in patients with urinary incontinence.","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9121322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Does body mass index affect anti-mullerian hormone levels in girls and adolescents? 体重指数会影响女孩和青少年的抗苗勒管激素水平吗?

IF 1.3 4区医学

Ginekologia polska Pub Date : 2023-03-17 DOI: 10.5603/GP.a2023.0013

Iwona Czech, Mirosław Partyka, Agnieszka Drosdzol-Cop

引用次数: 0

Pregnancy-associated gastric cancer. 妊娠相关胃癌。

IF 1.3 4区医学

Ginekologia polska Pub Date : 2023-03-17 DOI: 10.5603/GP.a2023.0008

Ewelina Stefanowicz, Piotr Minowski, Maja Bronk, Krzysztof Preis, Malgorzata Swiatkowska-Freund

引用次数: 0

Is it possible to predict the success of single dose methotrexate in the treatment of tubal ectopic pregnancies? 是否有可能预测单剂量甲氨蝶呤治疗输卵管异位妊娠的成功率?

IF 1.3 4区医学

Ginekologia polska Pub Date : 2023-03-17 DOI: 10.5603/GP.a2023.0004

Eren Pek, Fatma Beyzait, Duygu Siddikoglu

{"title":"Is it possible to predict the success of single dose methotrexate in the treatment of tubal ectopic pregnancies?","authors":"Eren Pek, Fatma Beyzait, Duygu Siddikoglu","doi":"10.5603/GP.a2023.0004","DOIUrl":"https://doi.org/10.5603/GP.a2023.0004","url":null,"abstract":"Objectives: In this study, the aim was to determine whether the use of endometrial thickness or neutrophil/lymphocyte and platelet/lymphocyte ratio would be useful in predicting the success of methotrexate in the treatment of ectopic pregnancies located in the fallopian tubes.Materal and methods: This study was carried out by retrospectively examining 68 study group cases with an ultrasonographically detectable gestational sac in the fallopian tubes and 189 control group cases with an unruptured ectopic pregnancy diagnosis at any location. The cut-off value of endometrial thickness was calculated as a new marker between the cases in which single-dose methotrexate treatment was successful and the cases with treatment failure. Treatment success was evaluated with different models including endometrial thickness, fetal cardiac activity status, measurable crown-rump length, and β-hCG.Result: The cut-off value of β-hCG for treatment success was determined as 2960.5 ng/mL, and the cut-off value for endometrial thickness was determined as 10.5 mm. Although NLR seems to be a marker with a cut-off value of 2.49, it does not provide an extra benefit in combined use as it is not a specific predictor. The highest success in predicting treatment success was achieved in the modeling in which crown-rump length + fetal cardiac activity + β-hCG + endometrial thickness were used together.Conclusions: The use of endometrial thickness as a marker seems to be quite reliable in predicting treatment success. And we think it would be beneficial to thin the endometrium before using methotrexate.","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9121323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The relevance of blood gases levels in newborns: the sampling matters. 新生儿血气水平的相关性:采样很重要。

IF 1.3 4区医学

Ginekologia polska Pub Date : 2023-03-17 DOI: 10.5603/GP.a2023.0015

Joanna Jassem-Bobowicz, Katarzyna Stefanska

引用次数: 0

Expression of heat shock proteins HSPA1A, HSPA1B and TP53 in vulval lichen planus and vulval lichen sclerosus. 热休克蛋白HSPA1A、HSPA1B和TP53在外阴扁平地衣和硬化性地衣中的表达。

IF 1.3 4区医学

Ginekologia polska Pub Date : 2023-03-17 DOI: 10.5603/GP.a2023.0011

Adrianna Marzec, Aleksandra Augusciak-Duma, Dominika Kupny-Bujoczek, Lukasz Witek, Anita Olejek, Iwona Gabriel

{"title":"Expression of heat shock proteins HSPA1A, HSPA1B and TP53 in vulval lichen planus and vulval lichen sclerosus.","authors":"Adrianna Marzec, Aleksandra Augusciak-Duma, Dominika Kupny-Bujoczek, Lukasz Witek, Anita Olejek, Iwona Gabriel","doi":"10.5603/GP.a2023.0011","DOIUrl":"https://doi.org/10.5603/GP.a2023.0011","url":null,"abstract":"Objectives: Heat shock proteins (HSPs) are proteins involved in protein folding and maturation. HSP expression is induced by heat shock or other stressors including cellular damage and hypoxia. The major groups, which are classified based on their molecular weight, include HSP27, HSP40, HSP60, HSP70, HSP90, and large HSP (HSP110 and glucose-regulated protein 170). The comparison of heat shock proteins and TP53 expression is yet not well studied in both vulval lichen sclerosus and lichen planus. Our aim was to assess the HSP and TP53 gene expression in women suffering from LS or LP and compare it within these groups and also healthy controls.Material and methods: The inclusion criteria were willingness to donate vulval biopsies, not currently or in the prior two weeks received any local nor systemic treatment for vulval disorder, age > 18 years old. The exclusion criteria were lack of consent, current vaginal infection confirmed with microbiological studies, current local or systemic treatment for vulval disease. 45 consecutive women were recruited into the study. All appropriate vulval samples were process by genetic analysis.Results: The mean expression (± SD) of HPSA1A for controls was 5.52 ± 3.18, for LS was 7.44 ± 2.16 and for LP was 7.89 ± 2.48. The mean expression (± SD) of HPSA1B for controls was 6.54 ± 3.41, for LS was 9.94 ± 6.88 and for LP was 9.43 ± 2.31. The mean expression (± SD) of TP53 for controls was 9.11 ± 1.14, for LS was 9.94 ± 1.27 and for LP was 10.41 ± 2.00. HSPA1A expression was 3,8 higher in women with lichen sclerosus than in control group.Conclusions: Heat shock protein-70 is more often expressed in LS than in healthy controls. HSP-70 not only supports tumor growth and metastasis, but on the other hand mat help to develop immune-driven treatment strategies.","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9121324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is the expression of placental epithelial and lymphoid markers associated with the perinatal outcomes in preeclampsia? 胎盘上皮和淋巴标记物的表达与子痫前期围产儿结局有关吗?

IF 1.3 4区医学

Ginekologia polska Pub Date : 2023-03-17 DOI: 10.5603/GP.a2023.0027

Zeynep Bayramoğlu, Sibel Özler

引用次数: 0

Prospective analysis of the impact of adjuvant treatment with external beam radiation therapy and vaginal brachytherapy on health-related quality of life in patients with early-stage endometrioid endometrial carcinoma. 外束放射辅助治疗和阴道近距离放疗对早期子宫内膜样癌患者健康相关生活质量影响的前瞻性分析

IF 1.3 4区医学

Ginekologia polska Pub Date : 2023-03-17 DOI: 10.5603/GP.a2023.0007

Adam Kluska, Bartlomiej Tomasik, Malgorzata Moszynska-Zielinska, Leszek Zytko, Natalia Tracz, Michal Spych, Jacek Fijuth, Leszek Gottwald

{"title":"Prospective analysis of the impact of adjuvant treatment with external beam radiation therapy and vaginal brachytherapy on health-related quality of life in patients with early-stage endometrioid endometrial carcinoma.","authors":"Adam Kluska, Bartlomiej Tomasik, Malgorzata Moszynska-Zielinska, Leszek Zytko, Natalia Tracz, Michal Spych, Jacek Fijuth, Leszek Gottwald","doi":"10.5603/GP.a2023.0007","DOIUrl":"https://doi.org/10.5603/GP.a2023.0007","url":null,"abstract":"Objectives: Our study evaluates the impact of adjuvant treatment with external beam radiotherapy (EBRT) combined with vaginal high dose rate brachytherapy (HDR BT) on health related quality of life (HRQL) in patients with early stage endometrioid endometrial carcinoma.Material and methods: From March 2019 to February 2021, 60 patients were enrolled with early stage endometrioid endometrial carcinoma, and qualified to adjuvant treatment after hysterectomy. HRQL was assessed using the EORTC QLQ-C30 questionnaire, with the endometrial cancer-specific HRQL module EORTC QLQ-EN24. Questionnaires were completed in four timepoints during adjuvant radiotherapy.Results: A significant decrease in mean global health status / quality of life (p < 0.001) and role functioning (p = 0.028) was noted, as assessed in EORTC QLQ-C30 scale. Among the EORTC QLQ-C30 symptoms scales, significant differences were noted in the fatigue scale (p = 0.003), pain scale (p = 0.001), constipation scale (p < 0.001) and diarrhea scale (p < 0.001) over time. The EORTC QRQ-EN24 analysis showed significant deterioration in the urological symptoms scale (p < 0.001), gastrointestinal symptoms scale (p < 0.001) and in the mean pain in back and pelvis scale (p = 0.003).Conclusions: Adjuvant radiotherapy in patients with early-stage endometrioid endometrial cancer after hysterectomy is associated with worse quality of life, especially due to the toxicity of the treatment in relation to the gastrointestinal tract and urinary system.","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9121321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Complications of planned home births in the Czech Republic. 捷克共和国计划在家分娩的并发症。

IF 1.3 4区医学

Ginekologia polska Pub Date : 2023-03-17 DOI: 10.5603/GP.a2023.0001

Petr Krepelka, Hynek Herman, Petr Velebil, Alena Mechurova, Jiri Hanacek, Zbynek Stranak, Jaroslav Feyereisl

{"title":"Complications of planned home births in the Czech Republic.","authors":"Petr Krepelka, Hynek Herman, Petr Velebil, Alena Mechurova, Jiri Hanacek, Zbynek Stranak, Jaroslav Feyereisl","doi":"10.5603/GP.a2023.0001","DOIUrl":"https://doi.org/10.5603/GP.a2023.0001","url":null,"abstract":"Objectives: This study evaluated complications that can occur during planned home births that require transfer to the hospital. These factors were assessed to improve the current status of deliveries performed outside health care facilities in the Czech Republic.Materials and methods: This prospective cohort study included data on 105 cases of complicated home births during 2017 to 2021 using an online form accessible to all hospital maternity wards in the Czech Republic.Results: Planned home births were complicated by fetal/neonatal causes, maternal causes, and combined fetomaternal complications in 28 (26.7%), 20 (19%), and 2 (1.9%) cases, respectively. The need for transfer was most often realized after the birth of the fetus (86; 81.9%); however, it was realized during birth in 19 (18.1%) cases. The following complications were noted most often: postpartum hemorrhage (23; 21.9%); neonatal asphyxia (17; 16.2); placental retention (14; 13.3%); birth injury (12; 11.4%); neonatal hypothermia (5; 4.8%); and placental birth (5; 4.8%). Indications for transfer during labor were as follows: labor obstruction (10; 9.5%); fetal hypoxia (5; 4.8%); bleeding during labor (2; 1.9%); preeclampsia (1; 0.9%); and fetal malformation (1; 0.9%). Perinatal death occurred in 8 (7.6%) cases. Permanent neonatal morbidity occurred in 4 (3.8%) cases.Conclusions: Patients with home birth complications were transferred to the hospital most often after the birth of the fetus. The low proportion of transfers during childbirth is caused by the unprofessional management of planned home births, resulting in a high number of perinatal deaths and high rate of permanent neonatal morbidity.","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9121331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of unilateral apical sling and laparoscopic sacrocolpopexy on the outcome in women with apical prolapse: randomised trial. 单侧根尖悬吊和腹腔镜骶colpop固定术对根尖脱垂女性患者预后的影响:随机试验。

IF 1.3 4区医学

Ginekologia polska Pub Date : 2023-03-17 DOI: 10.5603/GP.a2023.0002

Botagoz Aitbayeva, Serik Iskakov, Elena Lushchaeva, Galymzhan Toktarbekov, Kamilla Kenbayeva

{"title":"Effects of unilateral apical sling and laparoscopic sacrocolpopexy on the outcome in women with apical prolapse: randomised trial.","authors":"Botagoz Aitbayeva, Serik Iskakov, Elena Lushchaeva, Galymzhan Toktarbekov, Kamilla Kenbayeva","doi":"10.5603/GP.a2023.0002","DOIUrl":"https://doi.org/10.5603/GP.a2023.0002","url":null,"abstract":"Objectives: The purpose of this study was to compare the use of unilateral apical sling versus laparoscopic sacrocolpopexy in the treatment of the apical form of pelvic organ prolapse in women. M: aterial and methods:A prospective, single-center randomized trial included 100 patients who were alternately assigned to treatment. Each patient had a ≥ III stage of apical or anterior-apical prolapse determined by the POP-Q system. 45 accepted for unilateral apical sling (UAS)and 55 accepted for laparoscopic sacrocolpopexy (LS). Data were compared by the One-way ANOVA test using IBM SPSS stats 19.Results: Mean operating time was significantly greater in the LS group versus UAS group, 194.6 vs 42.4 minutes, respectively (p < 0.05). The amount of intraoperative bleeding was significantly higher in the UAS group, compared to the LS group (p = 0.01). Within the follow-up period, 2 patients in UAS group and 3 patients in LS group (4.4% vs 5.4%, respectively; p = 0.9) had recurrent cystocoele. HRQoL and sexual outcomes did not differ significantly between the two treatment groups.Conclusion: s:Our data demonstrate the non-superiority one on each other of the two different approaches, except in terms of shorter operating time and higher intraoperative bleeding when UAS used. These findings raise questions about the need for long-term results of quality of life outcomes for women with genital prolapse, especially in resource-limited settings similar to Kazakhstan.","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9121328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0