Platelet to lymphocyte and neutrophil to lymphocyte ratios in endometrial pathologies.

IF 1.2 4区医学 Q3 OBSTETRICS & GYNECOLOGY

Ginekologia polska Pub Date : 2023-01-01 DOI:10.5603/GP.a2021.0141

Orkun Ilgen, Sefa Kurt, Resmiye Irmak Yuzuguldu, Onur Ada, Alper Mankan

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引用次数: 4

Abstract

Objectives: Aim of this study was to evaluate the relationship between platelet to lymphocyte ratio (PLR), neutrophil to lymphocyte ratio (NLR), and endometrial pathologies.

Material and methods: The database of our institution was reviewed. Cases with endometrial pathology including endometrial cancer (EC), endometrial hyperplasia with atypia and without atypia, normal endometrial findings, between January 2015 to January 2020, were collected. Their CBC results and clinicopathologic data were determined. The relation between the platelet-lymphocyte ratio (PLR), neutrophil-lymphocyte ratio (NLR), and endometrial pathologies was evaluated.

Results: NLR was significantly higher in patients with endometrial cancer compared to other endometrial pathologies including endometrial hyperplasia with and without atypia and patients with normal endometrial findings. NLR cut-off value was determined 3.55 to discriminate cancer among other endometrial pathologies. PLR had not a significant difference between the endometrial pathologies.

Conclusion: NLR seems to be an effective and simple marker to discriminate endometrial cancer among endometrial pathologies by contrast with PLR.

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子宫内膜病理中血小板与淋巴细胞和中性粒细胞与淋巴细胞的比值。

目的:探讨血小板与淋巴细胞比值(PLR)、中性粒细胞与淋巴细胞比值(NLR)与子宫内膜病理的关系。材料和方法:查阅我院数据库。收集2015年1月至2020年1月期间子宫内膜病理包括子宫内膜癌(EC)、子宫内膜增生伴异型和非异型、子宫内膜正常的病例。测定两组患者的CBC结果和临床病理资料。评估血小板-淋巴细胞比值(PLR)、中性粒细胞-淋巴细胞比值(NLR)与子宫内膜病理的关系。结果:子宫内膜癌患者的NLR明显高于其他子宫内膜病变，包括伴有或不伴有异型的子宫内膜增生以及子宫内膜正常的患者。NLR临界值为3.55，用于区分癌与其他子宫内膜病变。不同子宫内膜病理间PLR差异无统计学意义。结论:与PLR相比，NLR是鉴别子宫内膜癌的一种简便有效的指标。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ginekologia polska OBSTETRICS & GYNECOLOGY-

CiteScore

2.00

自引率

15.40%

发文量

317

审稿时长

4-8 weeks

期刊介绍： Ginekologia Polska’ is a monthly medical journal published in Polish and English language. ‘Ginekologia Polska’ will accept submissions relating to any aspect of gynaecology, obstetrics and areas directly related. ‘Ginekologia Polska’ publishes original contributions, comparative works, case studies, letters to the editor and many other categories of articles.