Ginekologia polskaPub Date : 2025-01-01Epub Date: 2023-08-07DOI: 10.5603/GP.a2022.0004
Yingying Lin, Juan Lin, Zhiwei Chen, Xiaoyan Xiu, Ronghua Zhang, Lihua Lin, Jianying Yan
{"title":"Relationship between gestational weight gain during different phases and maternal complications or neonatal outcomes.","authors":"Yingying Lin, Juan Lin, Zhiwei Chen, Xiaoyan Xiu, Ronghua Zhang, Lihua Lin, Jianying Yan","doi":"10.5603/GP.a2022.0004","DOIUrl":"10.5603/GP.a2022.0004","url":null,"abstract":"<p><strong>Objectives: </strong>Improper gestational weight gain (GWG) causes many adverse obstetrical and neonatal outcomes. This study evaluates the relationship between weight gain in different phases and maternal outcomes or neonatal outcomes.</p><p><strong>Material and methods: </strong>Finally, this study recruited 2,608 women delivered at Fujian Provincial Maternity and Child Health, affiliated hospital of Fujian Medical University from December 2017 to January 2019. To evaluate the relationship between maternal outcome and neonatal outcome, the participants were divided into four groups based on their baseline BMI and weight gain in the second/third trimester of pregnancy.</p><p><strong>Results: </strong>This study demonstrated that neonate weight, small-for-gestational-age infants, macrosomia, neonatal death, cesarean delivery, and GDM significantly differed across the baseline BMI, weight gain in the second and third trimester. The umbilical cord's abnormality, bulging membrane, abruptio placentae, and postpartum hemorrhage were significantly related to baseline BMI. Furthermore, gestational hypertension and pre-eclampsia/eclampsia were significantly correlated with baseline BMI and weight gain in the second trimester. The maternal and infant outcomes are different, and the GWG curves are significantly different. Finally, multivariate regression analysis showed that baseline BMI and weight gain in the second/third trimester were the independent risk factors for GDM and macrosomia. Also, baseline BMI and weight gain in the third trimester were the independent risk factors for developing gestational hypertension and pre-eclampsia/eclampsia, respectively.</p><p><strong>Conclusions: </strong>The baseline BMI and weight gain in the second/third trimester are significant with maternal outcomes and neonatal outcomes to a varying degree. Thus, maintaining appropriate baseline BMI and weight gain in different phases are essential in preventing pregnancy complications and maternal and neonatal prognosis.</p>","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":" ","pages":"35-42"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10303558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ginekologia polskaPub Date : 2024-01-01Epub Date: 2023-09-05DOI: 10.5603/gpl.95367
Petra Guňková, Lubomír Tulinský, Daniel Toman, Lubomír Martínek, Adéla Vrtková, Richard Špaček, Ondřej Šimetka
{"title":"Acute appendicitis in pregnancy - do we treat correctly, or do we delay unnecessarily?","authors":"Petra Guňková, Lubomír Tulinský, Daniel Toman, Lubomír Martínek, Adéla Vrtková, Richard Špaček, Ondřej Šimetka","doi":"10.5603/gpl.95367","DOIUrl":"10.5603/gpl.95367","url":null,"abstract":"<p><strong>Objectives: </strong>Acute appendicitis is the most common non-gynaecological indication for surgical intervention during pregnancy. The aim of this study was to compare perioperative and postoperative results of surgical treatment of acute appendicitis in the early and late stage of pregnancy.</p><p><strong>Material and methods: </strong>This is a retrospective study focused on the evaluation of perioperative and postoperative results of appendectomy in pregnancy. The study included all pregnant patients who underwent laparoscopic or open appendectomy at the University Hospital Ostrava during the observed 10-year period (January 2012-December 2021). The patients were divided into two subgroups according to the stage of pregnancy in relation to the expected viability of the foetus (the viability limit was defined as the 23rd week of pregnancy).</p><p><strong>Results: </strong>In the monitored 10-year period, a total of 25 pregnant patients underwent appendectomy. Comparing the two subgroups of patients, there were no statistically significant differences in any of the admission parameters. Laparoscopy was performed in 100% of the patients in the lower stage of pregnancy (< 23 g.w.) and in 61% of the subgroup of patients with more advanced pregnancy (> 23 g.w.); this difference was statistically significant (p = 0.039). Differences in subgroups regarding duration of surgery, risk of revision and 30-day postoperative morbidity were not statistically significant. In the subgroup of patients < 23 g.w., uncomplicated forms of appendicitis predominated (66%), whereas in the subgroup > 23 g.w., complicated forms predominated (69%); this difference was statistically significant (p = 0.026). When comparing the two subgroups of patients, there was a statistically significant difference in the length of hospitalization (p = 0.006). The mortality rate of the group was zero.</p><p><strong>Conclusions: </strong>The results of the study confirm the fact that advanced pregnancy may be related to complicated forms of appendicitis. Therefore, early appendectomy is still the method of choice. In accordance with the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) recommendations, laparoscopic approach is preferred in pregnant patients, even in advanced pregnancy.</p>","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":" ","pages":"126-131"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10154000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ginekologia polskaPub Date : 2024-01-01Epub Date: 2023-05-10DOI: 10.5603/GP.a2022.0121
Jiao Zheng, Tingting Song, Ying Xu, Jia Li, Pengfei Liu, Jiangfang Zhang, Hong Yang
{"title":"Prenatal detection of chromosomal abnormalities and copy number variants in fetuses with corpus callosum agenesis.","authors":"Jiao Zheng, Tingting Song, Ying Xu, Jia Li, Pengfei Liu, Jiangfang Zhang, Hong Yang","doi":"10.5603/GP.a2022.0121","DOIUrl":"10.5603/GP.a2022.0121","url":null,"abstract":"<p><strong>Objectives: </strong>The corpus callosum is the main pathway that connects interhemispheric communication. Agenesis of corpus callosum (ACC) have not consistently detected replicate genetic risk factors, potentially due to Etiological heterogeneity of this trait. This study aimed to retrospectively analyze the molecular basis for the ACC and the potential genotyping-phenotyping association and provide the basis for genetic counselling.</p><p><strong>Material and methods: </strong>Karyotyping and chromosomal microarray analysis were performed for copy number variants.</p><p><strong>Results: </strong>Three cases had 1p36 deletions, two cases had 2q31.2 and 2p16.3 microdeletions, one case had microdeletion of Xq26.3q27.1, five cases involved derived chromosomes due to unbalanced translocations. These cases had variable deletions and duplications with partial overlapping. Phenotypically, besides agenesis of corpus callosum and other brain morphological abnormalities as well as heart abnormalities.</p><p><strong>Conclusions: </strong>ACC may occur alone or be related to other abnormal clinical phenotypes, and its genetic mechanism is very complicated. These results revealed ACC is associated with a variety of chromosomal abnormalities. The findings of the present study expand the genotypes associated with ACC, and further delineation of the genotype-phenotype correlations for ACC. With current applications of chromosome microarray analysis, congenital submicroscopic copy-number variations in fetuses can be detected more effectively.</p>","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":" ","pages":"824-829"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9809000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ginekologia polskaPub Date : 2024-01-01Epub Date: 2023-08-21DOI: 10.5603/gpl.94849
Hanna I Klimek, Hanna Moczulska, Piotr Sieroszewski
{"title":"Streptococcus mutans in the oral cavity as a risk factor for threatened miscarriage.","authors":"Hanna I Klimek, Hanna Moczulska, Piotr Sieroszewski","doi":"10.5603/gpl.94849","DOIUrl":"10.5603/gpl.94849","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study was to investigate the bacterial colonization of the oral and vaginal ecosystem in pregnant women during the first trimester of pregnancy.</p><p><strong>Material and methods: </strong>We analyzed 162 pregnant women, (99 women with threatened abortion and 63 women with healthy pregnancies). We collected oral and vaginal swabs, using PCR analysis to assess the presence of various bacteria (S. mutans, E. faecalis, E. coli, Lactobacillus acidophilus, Prevotella intermedia, Gardnerella vaginalis, S. agalactiae).</p><p><strong>Results: </strong>Results showed that the presence of Streptococcus mutans in the oral cavity was significantly more common in women with threatened abortion compared to those with healthy pregnancies (p = 0.046). The presence of Lactobacillus acidophilus in the vagina was significantly more common in women with healthy pregnancies (p = 0.041).</p><p><strong>Conclusions: </strong>Our study suggests that the presence of Streptococcus mutans in the oral cavity may be a risk factor for threatened abortion.</p>","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":" ","pages":"123-125"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10031965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ginekologia polskaPub Date : 2024-01-01Epub Date: 2023-09-15DOI: 10.5603/gpl.96864
Kamila Pokorska-Niewiada, Maciej Zietek, Malgorzata Swiatkowska-Freund, Malgorzata Szczuko
{"title":"How important are elements in polycystic ovary syndrome? Should they be supplemented? A systematic review.","authors":"Kamila Pokorska-Niewiada, Maciej Zietek, Malgorzata Swiatkowska-Freund, Malgorzata Szczuko","doi":"10.5603/gpl.96864","DOIUrl":"10.5603/gpl.96864","url":null,"abstract":"<p><p>Polycystic ovary syndrome (PCOS) is a multifactorial disorder with unknown etiology. The purpose of this systematic review is to analyze the available clinical trials on elemental supplementation in terms of improving biochemical parameters in women with PCOS. Electronic databases were searched from their inception until February 2023. Randomized controlled trials (RCTs) of PCOS during therapy with elemental supplementation alone or in combination with other elements were analyzed. Recommendations regarding supplementation with elements are not clear. There are many factors to consider, with the primary factor being the type of element and the possibility of supplementation and a balanced diet. Another aspect to consider is the presence of comorbidities, which may increase the demand for and absorption of elements. A final factor to be considered is the determination of the body's need for specific elements. Some elements may require supplementation (e.g., magnesium, selenium, iodine, calcium), while others (e.g., iron, copper, potassium, zinc, manganese, chromium) are in sufficient amounts in a proper diet, and some should be limited (e.g., sodium, phosphorus). It is necessary to determine the optimal dose of each element in order to improve the biochemical parameters of PCOS as much as possible, while at the same time avoiding the negative effects of excessive consumption.</p>","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":" ","pages":"143-151"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10242826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ginekologia polskaPub Date : 2024-01-01Epub Date: 2023-03-17DOI: 10.5603/GP.a2023.0005
Caglar Helvacioglu, Mustafa Eroğlu, Cem Yalçınkaya, Cumhur Selcuk Topal, Işıl Ada Akgul, Sumeyye Cimenli, İbrahim Kale
{"title":"Smooth muscle tumor of uncertain malignant potential (STUMP): a case-based analysis.","authors":"Caglar Helvacioglu, Mustafa Eroğlu, Cem Yalçınkaya, Cumhur Selcuk Topal, Işıl Ada Akgul, Sumeyye Cimenli, İbrahim Kale","doi":"10.5603/GP.a2023.0005","DOIUrl":"10.5603/GP.a2023.0005","url":null,"abstract":"<p><strong>Objectives: </strong>The present study aimed to analyze of uterine smooth muscle tumors of uncertain malignant potential (STUMP) and the outcomes of patients with STUMP.</p><p><strong>Material and methods: </strong>In this retrospective study, the data of patients diagnosed with STUMP in a single tertiary center between January 2005-January 2020 were reviewed. We assessed the demographic variables, treatment outcomes, time until recurrence, disease-free and overall survival of the patients.</p><p><strong>Results: </strong>Twenty-five patients diagnosed with STUMP were included in the study. The mean age of the patients was 43.2 ± 10.3 years. Thirteen of the 25 patients (52%) were treated by myomectomy, others received diagnoses following hysterectomy. The median follow-up time was 45.2 months. Recurrence was observed in three cases (12%), two of which were followed up without hysterectomy, and the third patient died by peritonitis carcinomatosa 60 months after diagnosis although she received cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) treatment.</p><p><strong>Conclusions: </strong>This study evaluates the data of patients with STUMP. Our results reveal a STUMP recurrence of 12%, like those previously reported in the literature. Despite the possibility of malignant recurrence, fertility-preserving treatment with close follow-up should be tried, because of the relatively early age at diagnosis.</p>","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":" ","pages":"590-595"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9121326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ginekologia polskaPub Date : 2024-01-01Epub Date: 2023-03-17DOI: 10.5603/GP.a2023.0017
Min Chen, Jianying Yan
{"title":"A preliminary integrated analysis of miRNA-mRNA expression profiles reveals a role of miR-146a-3p/TRAF6 in plasma from gestational diabetes mellitus patients.","authors":"Min Chen, Jianying Yan","doi":"10.5603/GP.a2023.0017","DOIUrl":"10.5603/GP.a2023.0017","url":null,"abstract":"<p><strong>Objectives: </strong>To utilize an integrative strategy to construct functional miRNA-mRNA regulatory networks by combining the reverse expression relationships between miRNAs and targets and computational predictions for gestational diabetes mellitus (GDM).</p><p><strong>Material and methods: </strong>A total of three microarray or RNA-seq datasets (GSE98043, GSE19649 and GSE92772) of plasma samples comparing GDM pregnant women and healthy control pregnant women were downloaded from the GEO database. The differentially expressed genes (DEmRNAs) and the differentially expressed miRNAs (DEmiRNAs) were analyzed. The target genes of DEmiRNAs were identified using two independent and complementary types of information: computational target predictions and expression relationships. An interaction network was constructed to identify hub genes of GDM. Another dataset (GSE92772) was used to externally verify the predictive ability of the hub genes.</p><p><strong>Results: </strong>A total of 264 DEmiRNAs and 1217 DEmRNAs were identified with Hsa-miR-146a-3p ranked first of DEmiRNAs. Functions of GDM-related miRNAs were mainly enriched in the glypican pathway, proteoglycan syndecan-mediated signaling events, and syndecan-1-mediated signaling events. A total of 47 target genes, including TRAF6, were shared between the computational target predictions and DEmRNAs and were identified as target genes of hsa-miR-146a-3p. The interaction network analysis identified TRAF6, CASP8, PTPN6, and CHD3 as hub genes involved in the pathophysiological process of GDM. Next, independent external validation was performed using the GSE19649 dataset. The expression of TRAF6, CASP8 and CHD3 in eight pairs of GDM blood samples was confirmed to be higher than that in healthy pregnant women blood samples with a AUC of 0.813, 0.813, and 0.703, respectively.</p><p><strong>Conclusions: </strong>Our preliminary analysis revealed that miR-146a-3p/TRAF6 might play a central role in the pathogenesis of GDM. Three hub genes, TRAF6, CASP8, and CHD3, were identified and independently externally validated as potential GDM noninvasive serum markers for future biomarkers research.</p>","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":" ","pages":"627-635"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9121333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ginekologia polskaPub Date : 2024-01-01Epub Date: 2023-03-17DOI: 10.5603/GP.a2023.0022
Pawel Szymanowski, Wioletta K Szepieniec, Hanna Szweda, Janusz Ligeza, Anna Sadakierska-Chudy
{"title":"Apical defect - the essence of cystocele pathogenesis?","authors":"Pawel Szymanowski, Wioletta K Szepieniec, Hanna Szweda, Janusz Ligeza, Anna Sadakierska-Chudy","doi":"10.5603/GP.a2023.0022","DOIUrl":"10.5603/GP.a2023.0022","url":null,"abstract":"<p><strong>Objectives: </strong>Lack of standardization causes misunderstandings in planning of cystocele treatment and the evaluation of surgical method effectiveness. The POP-Q System and DeLancey's three levels of pelvic support do not account for the phenomenon of cystocele caused by an apical defect. We aimed to evaluate the impact of level I defect on the formation of cystocele.</p><p><strong>Material and methods: </strong>Women reporting complaints related to bladder prolapse (cystocele) were subjected to a urogynecological examination. For this purpose, a simple and standardized method was used, based on the POP-Q System and DeLancey's three levels of pelvic support. Furthermore, it was expanded by evaluating the impact of level I defect (apical defect) on prolapse at level II of the anterior compartment.</p><p><strong>Results: </strong>In total, contribution of an apical defect to the pathogenesis of cystocele was founded in 72.2% of 302 female patients included in this study. In 30.8% the cystocele was caused exclusively by an apical defect. In turn, in 41.4% of patients, it resulted from concomitant apical and level II defect of the anterior compartment (lateral or central).</p><p><strong>Conclusions: </strong>The results of this study indicate that an apical defect may play a significant role in the development of a cystocele. Hence, it could be essential to take the influence of an apical defect on level II in anterior compartment into account when planning a surgical procedure. The authors suggest that lack of such procedures potentially exposes some cystocele patients to ineffective treatment.</p>","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":" ","pages":"511-517"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9121325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ginekologia polskaPub Date : 2024-01-01Epub Date: 2023-01-04DOI: 10.5603/GP.a2022.0144
Lukasz Janas, Grzegorz Stachowiak, Ewa Glowacka, Iwona Piwowarczyk, Magdalena Kajdos, Malwina Soja, Martyna Masternak, Marek Nowak
{"title":"The use of CA125, human epididymis protein 4 (HE4), risk of ovarian malignancy algorithm (ROMA), risk of malignancy index (RMI) and subjective assessment (SA) in preoperative diagnosing of ovarian tumors.","authors":"Lukasz Janas, Grzegorz Stachowiak, Ewa Glowacka, Iwona Piwowarczyk, Magdalena Kajdos, Malwina Soja, Martyna Masternak, Marek Nowak","doi":"10.5603/GP.a2022.0144","DOIUrl":"10.5603/GP.a2022.0144","url":null,"abstract":"<p><strong>Objectives: </strong>To compare utility of CA125, human epididymis protein 4 (HE4), risk of ovarian malignancy algorithm (ROMA), risk of malignancy index (RMI) and subjective assessment (SA) in preoperative diagnosis of ovarian tumors.</p><p><strong>Material and methods: </strong>Research was conducted among 456 patients qualified for surgery due to ovarian tumor. Preoperatively, CA125 and HE4 serum levels were estimated, and transvaginal ultrasound was performed. ROMA and RMI values and SA qualifications were obtained. Results were compared with pathomorphological findings.</p><p><strong>Results: </strong>Receiver Operating Characteristic (ROC)-Area Under Curve (AUC) values for CA125, HE4, ROMA, RMI and SA in preoperative diagnosis of malignant lesions were 0.819, 0.909, 0.911, 0.895 and 0.895, respectively. Combinations of biochemical and sonographic methods increased sensitivity in diagnosis of ovarian tumors. Combinations utilizing serum HE4 concentrations were most useful.</p><p><strong>Conclusions: </strong>CA125, HE4, ROMA, RMI and SA proved to be useful in preoperative diagnosis of ovarian tumors. HE4 and ROMA occurred to be the most useful. Ultrasonographic methods are considerably useful in diagnosis of ovarian tumors. RMI and SA present similar overall diagnostic value.</p>","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":" ","pages":"321-327"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10533203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of the efficacy of oral contraceptives and levonorgestrel intrauterine system in intermenstrual bleeding caused by uterine niche.","authors":"Fengque Zheng, Saiqiong Chen, Weiwei Yang, Jingjing Li, Qinxi Huang, Huayi Qin, Jiahan Wei, Jiajing Lin","doi":"10.5603/GP.a2023.0067","DOIUrl":"10.5603/GP.a2023.0067","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to compare the effectiveness of oral contraceptives and a levonorgestrel intrauterine system in treating intermenstrual bleeding due to uterine niche.</p><p><strong>Material and methods: </strong>We retrospectively analyzed 72 patients with intermenstrual bleeding due to uterine niche from January 2017 to December 2021, of whom 41 were treated with oral contraceptives and 31 with a levonorgestrel intrauterine system. Post-treatment follow-ups at 1, 3, and 6 months were conducted to compare the efficiency and adverse effects between the two groups.</p><p><strong>Results: </strong>In the oral contraceptive group, the effectiveness rate was higher than 80% at 1- and 3-months post-treatment and higher than 90% at 6 months. In the levonorgestrel intrauterine system group, the effectiveness rates were 58.06%, 54.84%, and 61.29% at 1, 3, and 6 months of treatment, respectively.</p><p><strong>Conclusions: </strong>Oral contraceptives were more effective than the levonorgestrel intrauterine system in treating intermenstrual bleeding caused by uterine niche.</p>","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":" ","pages":"621-626"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9755825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}