Ginekologia polska最新文献

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Sufentanil for carboprost-induced adverse reactions during cesarean delivery under combined spinal-epidural anesthesia. 舒芬太尼治疗腰硬联合麻醉下剖宫产时卡前列素引起的不良反应。
IF 1.3 4区 医学
Ginekologia polska Pub Date : 2023-01-01 DOI: 10.5603/GP.a2021.0262
Qian Hu, Jin Guo, Peng Bai, Xue Xiao, Teng He, Peng Yang, Huafeng Li, Lin Zhang
{"title":"Sufentanil for carboprost-induced adverse reactions during cesarean delivery under combined spinal-epidural anesthesia.","authors":"Qian Hu,&nbsp;Jin Guo,&nbsp;Peng Bai,&nbsp;Xue Xiao,&nbsp;Teng He,&nbsp;Peng Yang,&nbsp;Huafeng Li,&nbsp;Lin Zhang","doi":"10.5603/GP.a2021.0262","DOIUrl":"https://doi.org/10.5603/GP.a2021.0262","url":null,"abstract":"<p><strong>Objectives: </strong>Carboprost plays an important role in managing refractory uterine atony and severe postpartum hemorrhage. However, it is associated with challenging adverse reactions. We aimed to evaluate the clinical effects of low dose sufentanil on the prevention of adverse events associated with carboprost during cesarean delivery.</p><p><strong>Material and methods: </strong>Patients were randomly divided into two groups: a placebo control group (group C, n = 15) that received an intravenous infusion of 1 mL of normal saline 2 min before carboprost and a sufentanil group (group S, n = 15) that received 5 μg of sufentanil. The primary outcome was the incidence of nausea and vomiting following carboprost administration.</p><p><strong>Results: </strong>The incidence of nausea, vomiting, and gastrointestinal discomfort was significantly lower in group S than in group C (p < 0.05).</p><p><strong>Conclusions: </strong>The prophylactic use of low dose sufentanil reduces the incidence of gastrointestinal side effects caused by carboprost administration during cesarean section.</p>","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":"94 5","pages":"379-388"},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9718407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The impact of splenectomy and diaphragmatic surgery on perioperative morbidity and overall survival of ovarian cancer patients. 脾切除和膈手术对卵巢癌患者围手术期发病率和总生存率的影响。
IF 1.2 4区 医学
Ginekologia polska Pub Date : 2023-01-01 Epub Date: 2023-03-17 DOI: 10.5603/GP.a2023.0028
Artur Skowyra, Sebastian Szubert, Tomasz Rajs, Blazej Nowakowski, Lukasz Wicherek
{"title":"The impact of splenectomy and diaphragmatic surgery on perioperative morbidity and overall survival of ovarian cancer patients.","authors":"Artur Skowyra, Sebastian Szubert, Tomasz Rajs, Blazej Nowakowski, Lukasz Wicherek","doi":"10.5603/GP.a2023.0028","DOIUrl":"10.5603/GP.a2023.0028","url":null,"abstract":"<p><strong>Objectives: </strong>The prognosis of ovarian cancer (OC), among other factors, depends on residual disease after primary debulking surgery (PDS) and initial disease advancement. The main aim of our study was to evaluate the survival benefits of splenectomy and diaphragmatic surgery in OC patients, when the procedures result in resection to no macroscopic residual disease or minimal residual disease [tumor nodules below 2.5 mm according to Sugarbaker's completeness of cytoreduction score (CC) = 1].</p><p><strong>Material and methods: </strong>The study included 25 OC patients after splenectomy procedures, 28 patients after diaphragmatic surgery and 17 patients who had undergone both splenectomy and diaphragmatic surgery. Patients' overall survival (OS) was compared with residual disease-matched controls (47 patients) who had upper abdomen involvement but no requirement for splenectomy and/or diaphragmatic surgery.</p><p><strong>Results: </strong>Overall survival of patients after splenectomy was not significantly different from OS of patients who did not required splenectomy (36.1 vs 31.6 months; p = 0.85). No differences in OS were observed between patients who did and did not require diaphragmatic surgery (31.3 vs 41.8; p = 0.33). Similarly, we found no differences in OS between patients who underwent both splenectomy and diaphragmatic surgery and those patients who did not require either procedure (20.1 vs 31.6 months; p = 0.45). Splenectomies and diaphragmatic surgeries were associated with prolonged hospitalization and length of surgery, however, no specific morbidity related to the procedures was observed.</p><p><strong>Conclusions: </strong>In the cases of advanced OC, diaphragm and spleen involvement do not hamper patient prognosis when adequately resected.</p>","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":" ","pages":"807-815"},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9173813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of gestational diabetes and other maternal factors on neonatal body composition in the first week of life: a case-control study. 妊娠期糖尿病及其他母体因素对新生儿出生第一周身体组成的影响:一项病例对照研究
IF 1.3 4区 医学
Ginekologia polska Pub Date : 2023-01-01 DOI: 10.5603/GP.a2021.0249
Karolina Karcz, Matylda Czosnykowska-Lukacka, Barbara Krolak-Olejnik
{"title":"Impact of gestational diabetes and other maternal factors on neonatal body composition in the first week of life: a case-control study.","authors":"Karolina Karcz,&nbsp;Matylda Czosnykowska-Lukacka,&nbsp;Barbara Krolak-Olejnik","doi":"10.5603/GP.a2021.0249","DOIUrl":"https://doi.org/10.5603/GP.a2021.0249","url":null,"abstract":"<p><strong>Objectives: </strong>Newborns of diabetic mothers are at increased risk of abnormal nutritional status at birth, thus developing metabolic disorders. The aim of this study was to evaluate the anthropometric measurements and body composition of newborns born to mothers with gestational diabetes in comparison to newborns born to mothers with normal glucose tolerance in pregnancy, in the first week of their life. Maternal factors affecting the gestational period were also evaluated.</p><p><strong>Material and methods: </strong>The study included 70 participants: neonates born to mothers with gestational diabetes (GDM) and neonates born to healthy mothers (non-GDM). A set of statistical methods (e.g., ANOVA, Kruskal-Wallis test, Chi-square test, regression, cluster analysis) was used to compare data between the study groups and to find their association with maternal factors.</p><p><strong>Results: </strong>Our approach resulted in statistically significant classification (p < 0.05) by maternal history of hypothyroidism, weight gain during pregnancy and diagnosis of GDM. Newborns of mothers diagnosed with both GDM and hypothyroidism had lower birth weight and fat mass than newborns of mothers without GDM nor hypothyroidism (p < 0.05), however this finding might be associated with high incidence of excessive gestational weight gain among healthy mothers. No differences in body composition were found between the study groups on account of maternal GDM only (p > 0.05).</p><p><strong>Conclusions: </strong>Thus, well-controlled gestational diabetes mellitus as an individual factor does not significantly affect neonatal anthropometric measurements and body composition.</p>","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":"94 2","pages":"119-128"},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9330796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case report of laparoscopic pectopexy in a patient with an ectopic kidney and POP-Q III grade apical prolapse. 一名患有异位肾脏和 POP-Q III 级肾尖脱垂的患者腹腔镜下切除术的病例报告。
IF 1.2 4区 医学
Ginekologia polska Pub Date : 2023-01-01 Epub Date: 2023-03-17 DOI: 10.5603/GP.a2023.0009
Paulina Szymczak, Dariusz G Wydra
{"title":"A case report of laparoscopic pectopexy in a patient with an ectopic kidney and POP-Q III grade apical prolapse.","authors":"Paulina Szymczak, Dariusz G Wydra","doi":"10.5603/GP.a2023.0009","DOIUrl":"10.5603/GP.a2023.0009","url":null,"abstract":"","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":" ","pages":"768-769"},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9492540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Breast injury as a manifestation of distant-metastatic ovarian cancer: a case report. 乳腺损伤作为远处转移性卵巢癌的表现:1例报告。
IF 1.3 4区 医学
Ginekologia polska Pub Date : 2023-01-01 DOI: 10.5603/GP.a2022.0149
Pawel Topolewski, Marcin Sniadecki, Marcin Liro, Pawel Guzik, Dariusz Wydra
{"title":"Breast injury as a manifestation of distant-metastatic ovarian cancer: a case report.","authors":"Pawel Topolewski,&nbsp;Marcin Sniadecki,&nbsp;Marcin Liro,&nbsp;Pawel Guzik,&nbsp;Dariusz Wydra","doi":"10.5603/GP.a2022.0149","DOIUrl":"https://doi.org/10.5603/GP.a2022.0149","url":null,"abstract":"","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":"94 1","pages":"84-85"},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10798673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chronic endometritis - is it time to clarify diagnostic criteria? 慢性子宫内膜炎——是时候明确诊断标准了吗?
IF 1.3 4区 医学
Ginekologia polska Pub Date : 2023-01-01 DOI: 10.5603/GP.a2022.0147
Katarzyna Klimaszyk, Henriette Svarre Nielsen, Ewa Wender-Ozegowska, Malgorzata Kedzia
{"title":"Chronic endometritis - is it time to clarify diagnostic criteria?","authors":"Katarzyna Klimaszyk,&nbsp;Henriette Svarre Nielsen,&nbsp;Ewa Wender-Ozegowska,&nbsp;Malgorzata Kedzia","doi":"10.5603/GP.a2022.0147","DOIUrl":"https://doi.org/10.5603/GP.a2022.0147","url":null,"abstract":"<p><p>Chronic endometritis is a persistent, low-intensity inflammation of endometrial mucosa, characterized by the infiltration of plasma cells into the endometrial stroma This immunological alteration is thought to be a consequence of a bacterial infection. For a long time, chronic endometritis was poorly investigated and rarely considered in clinical practice because it is either asymptomatic or presents with no specific symptoms. Its association with adverse effects on fertility and retrospectively reported effectiveness of antibiotic treatment were the main reasons for a growing interest in this endometrial pathology. Chronic endometritis is now a hot topic in recurrent pregnancy loss and recurrent implantation failure research. Nevertheless, there are still no recommendations to include chronic endometritis investigation in a clinical evaluation of infertile patients. The uncertain role of this condition is an effect of significant differences in study results presented by different research groups. One important reason for these inconsistent findings is a lack of standardised chronic endometritis diagnostic methods. We present a review of the literature, focusing on the currently available chronic endometritis diagnostic techniques. The review is subdivided into three parts concerning the diagnostic accuracy of three main diagnostic modalities. Histopathological examination of endometrial tissue, hysteroscopic evaluation of uterine cavity and identification of the bacterial factor. In conclusion, it is of great importance to establish a consensus on the diagnostic criteria for chronic endometritis. This is the only way to enhance international cooperation and create well-design multicenter studies to evidence the role of this endometrial pathology in infertility.</p>","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":"94 2","pages":"152-157"},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9272340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The influence of preincubation time of prepared sperm before IVF on fertilization, embryo developmental competence and the reproductive outcomes. 体外受精前预孵育时间对受精、胚胎发育能力及生殖结局的影响。
IF 1.3 4区 医学
Ginekologia polska Pub Date : 2023-01-01 DOI: 10.5603/GP.a2021.0078
Sai Liu, Guoxuan Wu, Li Wang, Yanyan Zhao, Yongqing Lv, Nannan Dang, Yuanqing Yao
{"title":"The influence of preincubation time of prepared sperm before IVF on fertilization, embryo developmental competence and the reproductive outcomes.","authors":"Sai Liu,&nbsp;Guoxuan Wu,&nbsp;Li Wang,&nbsp;Yanyan Zhao,&nbsp;Yongqing Lv,&nbsp;Nannan Dang,&nbsp;Yuanqing Yao","doi":"10.5603/GP.a2021.0078","DOIUrl":"https://doi.org/10.5603/GP.a2021.0078","url":null,"abstract":"<p><strong>Objectives: </strong>It has been provided that if incubation time of prepared sperm can affect sperm motility and DNA fragment, but little is known about the influence of sperm preincubation time (SI) on the sperm's fertilizing ability, subsequent embryonic development and pregnancy outcomes in in vitro fertilization (IVF). The aim of this study was to explore the association of SI with fertilization rate, embryo development and clinical outcomes in IVF, further, to find an optimal preincubation time for prepared sperm before insemination in IVF.</p><p><strong>Material and methods: </strong>This retrospective cohort study included a total of 1453 infertile couples undergoing IVF in our center performed from January 2016 to January 2019. Sperm were preincubated at 37℃ 6% CO₂ for different times before insemination. Preincubation time associated with fertilization rate (FR), 2PN rate, D3 good quality embryo rate, fresh embryo implantation rate (IR), blastocyst formation rate, cumulative pregnancy rate (CPR), cumulative ongoing pregnancy rate (COPR), cumulative live birth rate (CLBR), newborn health and gender ratio were analyzed by chi-square analysis.</p><p><strong>Results: </strong>FR and 2PN rate of SI more than four hours SI groups (> 4 h SI group) decreased significantly compared with other SI groups (p < 0.01). There were no significant differences of the D3 high quality embryo rate among five SI groups. The blastocyst formation rate of > 4 h SI group was significantly lower than that of 2-3 h SI group (45.5% vs 56.1%, p < 0.05); and 1-2 h SI group also had significant difference with 2-3 h and 3-4 h SI group (48.9% vs 56.1% and 54.6%, p < 0.05). There were a significant decrease of fresh IR and CPR in ≤1 h SI group compared with 1-2 h SI group (19.6% vs. 38.0%, p < 0.05; 62.7% vs 73.7%, p < 0.05); ≤ 1 h SI group also have the lowest CLBR (45.6%), it had statistic differences with 1-2 SI group and 3-4 SI group (45.6% vs 63.2%, p < 0.01; 45.6% vs 61.2%, p < 0.05).</p><p><strong>Conclusions: </strong>The sperm preincubated time at 37℃ 6% CO₂ before insemination could influence sperm fertilizing ability, blastocyst formation, embryo implantation and CLBR in IVF cycles. The best time for prepared sperm preincubation at 37℃ is one to four hours before insemination in IVF.</p>","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":"94 2","pages":"107-112"},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9630595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Testing of new instrument for measuring quality and diversity of nutrition in pregnancy. 妊娠期营养质量和营养多样性测量新仪器的试验。
IF 1.3 4区 医学
Ginekologia polska Pub Date : 2023-01-01 DOI: 10.5603/GP.a2021.0227
Jovana Milosavljević, Ana Pejčić, Petar Arsenijević, Aleksandra Dimitrijević, Miloš Milosavljević, Dejan Mihajlović, Slobodan Janković
{"title":"Testing of new instrument for measuring quality and diversity of nutrition in pregnancy.","authors":"Jovana Milosavljević,&nbsp;Ana Pejčić,&nbsp;Petar Arsenijević,&nbsp;Aleksandra Dimitrijević,&nbsp;Miloš Milosavljević,&nbsp;Dejan Mihajlović,&nbsp;Slobodan Janković","doi":"10.5603/GP.a2021.0227","DOIUrl":"https://doi.org/10.5603/GP.a2021.0227","url":null,"abstract":"<p><strong>Objectives: </strong>Our aim was construction and development of a new questionnaire for assessing the quality and diversity of nutrition of pregnant women.</p><p><strong>Material and methods: </strong>This was a cross-sectional study. The novel questionnaire was developed through eight steps according with internationally accepted guidelines for questionnaire development. The questionnaire with 18 questions and answers according to the Likert's scale was created and called Balkan Food Quality and Diversity in Pregnancy Questionnaire-18 (BFQDPQ-18). Reliability testing and factor analysis of BFQDPQ-18 were carried out on a sample of 382 women in the third trimester of pregnancy whose pregnancy control and monitoring were performed at the Clinic for Gynecology and Obstetrics of the Clinical Center in Kragujevac, Serbia.</p><p><strong>Results: </strong>The first test of reliability indicated high levels of internal consistency, with the Cronbach's alpha of 0.85 of the BFQDPQ-18. After dividing the BFQDPQ-18 into two parts of nine questions each by split-half method, the Cronbach's alphas were 0.799 and 0.716. The Kaiser-Meyer-Olkin Measure of Sampling Adequacy (KMO) was 0.878, and the Bartlett's test of sphericity: 1,892.206, p < 0.000. Factor analysis revealed four factors explained in total 51.99% of the variance: mean meal and snack, foods with a low degree of industrial processing, subjective assessment of dietary quality and starchy foods.</p><p><strong>Conclusions: </strong>The final version of the BFQDPQ-18 showed high reliability and good psychometric properties, so we believe it could be useful instrument for assessing the quality of nutrition of pregnant women.</p>","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":"94 1","pages":"73-78"},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10796894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Comparison of labor duration of induced labor with dinoprostone insert vs spontaneous labor. 使用地诺前列酮引产与自然分娩的产程比较。
IF 1.2 4区 医学
Ginekologia polska Pub Date : 2023-01-01 Epub Date: 2023-08-07 DOI: 10.5603/GP.a2023.0070
Katarzyna A Skibinska, Magdalena Kolak, Agnieszka Micek, Hubert Huras, Andrzej Jaworowski
{"title":"Comparison of labor duration of induced labor with dinoprostone insert vs spontaneous labor.","authors":"Katarzyna A Skibinska, Magdalena Kolak, Agnieszka Micek, Hubert Huras, Andrzej Jaworowski","doi":"10.5603/GP.a2023.0070","DOIUrl":"10.5603/GP.a2023.0070","url":null,"abstract":"<p><strong>Objectives: </strong>Labor induction is one of the most common procedures in modern obstetrics. One in five pregnant women and 30-40% of women delivering vaginally undergo this procedure. If the cervical status is unfavorable, a ripening process is used prior to induction to shorten the duration of oxytocin administration and maximize the possibility of vaginal birth. The aim of this study was to compare the duration of labor induced with dinoprostone vaginal insert to spontaneous labor.</p><p><strong>Material and methods: </strong>It was a retrospective study conducted between May 2019 and February 2021 in the tertiary reference center, the Obstetrics and Perinatology Department of the Jagiellonian University Hospital in Krakow. The research group involved 182 patients in singleton pregnancy at term, qualified for cervical ripening procedure. The control group consisted of 178 patients that were delivering spontaneously and admitted to the delivery ward in the first stage of labor. Statistical analysis was performed to compare the duration of labor between groups. To find factors affecting the procedure we compared different models consisting of maternal and fetal characteristics.</p><p><strong>Results: </strong>Successful vaginal delivery in the dinoprostone group was achieved in the group of 88% of patients. There was no significant difference in labor duration between the groups: 315 minutes in the study group and 300 min in the control group. Only being primipara was a factor related to longer labor in both groups.</p><p><strong>Conclusions: </strong>Pre-induction with dinoprostone insert and additional foley catheter, if indicated, does not make labor longer in comparison with spontaneous labor.</p>","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":" ","pages":"984-989"},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10319620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of COVID-19 infection on placental function. COVID-19感染对胎盘功能的影响。
IF 1.3 4区 医学
Ginekologia polska Pub Date : 2023-01-01 DOI: 10.5603/GP.a2022.0139
Izabela Pilarska, Magdalena Bizon, Wlodzimierz Sawicki
{"title":"Influence of COVID-19 infection on placental function.","authors":"Izabela Pilarska,&nbsp;Magdalena Bizon,&nbsp;Wlodzimierz Sawicki","doi":"10.5603/GP.a2022.0139","DOIUrl":"https://doi.org/10.5603/GP.a2022.0139","url":null,"abstract":"<p><strong>Objectives: </strong>Pregnant women are more susceptible to infectious diseases because of their natural immunosuppression. SARS-CoV-2 seems to be a potential risk for the condition of women and the fetus. Unfortunately, knowledge of the influence of coronavirus disease 19 (COVID-19) on pregnant women and their children is still very limited, and further investigation and analysis are needed. The aim of the study was to conduct a meta-analysis of research about the impact of COVID-19 on the placenta.</p><p><strong>Material and methods: </strong>Articles published between 2020 and 2021 and contained in the PubMed and Elsevier databases were analyzed.</p><p><strong>Results: </strong>The SARS-CoV-2 infection also led to pregnancy complications in the patients. The most common pregnancy complications include caesarean delivery (80%), preterm delivery (26%), fetal distress (8%), premature rupture of the membranes (9%) and stillbirth (2%). Among the observed patients, neonatal complications occurred, such as premature delivery (25%), respiratory distress syndrome (8%), pneumonia (8%) and deaths of 4 newborns SARS-CoV-2 was found mainly in syncytiotrophoblast cells at the maternal-fetal border of the placenta. Histological examination of the placenta revealed dense macrophage infiltration. Abnormal perfusion of fetal blood vessels or fetal vascular thrombosis was observed. Elevated levels of SARS-CoV-2 IgG or IgM antibodies in the umbilical cord blood were observed in nine newborns, reported as evidence of vertical infection.</p><p><strong>Conclusions: </strong>The features of placental damage in women with COVID-19 are clearly different from the control group. Further research is needed to better understand how SARS-CoV-2 infection affects the placenta.</p>","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":"94 1","pages":"79-83"},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10779885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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