SARS-CoV-2 infection during pregnancy - single-center retrospective study.

IF 1.2 4区 医学 Q3 OBSTETRICS & GYNECOLOGY
Ginekologia polska Pub Date : 2023-01-01 Epub Date: 2023-08-21 DOI:10.5603/gpl.95565
Malgorzata Skalska-Swistek, Magdalena Kolak, Andrzej P Jaworowski, Rafal Swistek, Agnieszka Micek, Hubert Huras
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引用次数: 0

Abstract

Objectives: The SARS-CoV-2 virus infection has spread to almost all countries in the last two years. Pregnancy complicated with COVID-19 is a unique situation and challenge for doctors. The study aimed to evaluate obstetric results, and biochemical test results and to analyze the treatment used in pregnant patients complicated with COVID-19 infection.

Material and methods: A retrospective analysis of 146 pregnant patients hospitalized at the Department of Obstetrics and Perinatology Jagiellonian University Medical College (JUMC) in Krakow was conducted from July 2020 to August 2021.

Results: In the analyzed group respiratory failure occurred in 19.19% of cases and intravascular coagulation syndrome (DIC) in 1.37%. One patient died (0.68%). 16.6% of cases were transferred to the Intensive Care Unit (ICU) and required intubation. The remaining cases were mild: 39.04% were asymptomatic, 41.78% reported cough, 30.82% dyspnoea and 23.97% myalgia. In the laboratory tests increased values of CRP and IL-6 were observed with normal levels of leukocytes. Additionally, a decreased level of total protein and an increased level of d-dimers were detected. 98.63% of patients received a prophylactic dose of low molecular weight heparin. 46.58% of cases needed additional antibiotic therapy. Cesarean sections were performed in 59.59% of cases. The children were born in good general condition. Vertical transmission of SARS-CoV-2 to the newborn has not been confirmed.

Conclusions: Data from the above study show a significant effect of COVID-19 on pregnant patients. Almost one in five pregnant women occurred respiratory failure and most of them had to be transferred to the ICU department and had to be intubated.

妊娠期SARS-CoV-2感染-单中心回顾性研究
目标:在过去两年中,严重急性呼吸系统综合征冠状病毒2型感染已传播到几乎所有国家。妊娠合并新冠肺炎对医生来说是一种独特的情况和挑战。本研究旨在评估产科结果和生化检测结果,并分析妊娠合并新冠肺炎感染患者的治疗方法。材料和方法:对2020年7月至2021年8月在克拉科夫贾吉隆大学医学院妇产科和围产期住院的146名孕妇进行了回顾性分析。结果:在分析组中,19.19%的病例发生呼吸衰竭,1.37%的病例发生血管内凝血综合征。1名患者死亡(0.68%)。16.6%的病例被转移到重症监护室(ICU),需要插管。其余病例为轻度:39.04%无症状,41.78%报告咳嗽,30.82%呼吸困难和23.97%肌痛。在实验室测试中,在白细胞水平正常的情况下,观察到CRP和IL-6的值增加。此外,检测到总蛋白水平降低和d-二聚体水平增加。98.63%的患者接受了预防剂量的低分子量肝素。46.58%的病例需要额外的抗生素治疗。59.59%的病例进行了剖宫产。孩子们出生时身体状况良好。严重急性呼吸系统综合征冠状病毒2型向新生儿的垂直传播尚未得到证实。结论:上述研究数据显示,新冠肺炎对孕妇有显著影响。几乎五分之一的孕妇出现呼吸衰竭,其中大多数不得不被转移到重症监护室并进行插管。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Ginekologia polska
Ginekologia polska OBSTETRICS & GYNECOLOGY-
CiteScore
2.00
自引率
15.40%
发文量
317
审稿时长
4-8 weeks
期刊介绍: Ginekologia Polska’ is a monthly medical journal published in Polish and English language. ‘Ginekologia Polska’ will accept submissions relating to any aspect of gynaecology, obstetrics and areas directly related. ‘Ginekologia Polska’ publishes original contributions, comparative works, case studies, letters to the editor and many other categories of articles.
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