Ginekologia polska最新文献_第6页

Pregnancy-associated gastric cancer. 妊娠相关胃癌。

IF 1.3 4区医学

Ginekologia polska Pub Date : 2023-03-17 DOI: 10.5603/GP.a2023.0008

Ewelina Stefanowicz, Piotr Minowski, Maja Bronk, Krzysztof Preis, Malgorzata Swiatkowska-Freund

引用次数: 0

Expression of heat shock proteins HSPA1A, HSPA1B and TP53 in vulval lichen planus and vulval lichen sclerosus. 热休克蛋白HSPA1A、HSPA1B和TP53在外阴扁平地衣和硬化性地衣中的表达。

IF 1.3 4区医学

Ginekologia polska Pub Date : 2023-03-17 DOI: 10.5603/GP.a2023.0011

Adrianna Marzec, Aleksandra Augusciak-Duma, Dominika Kupny-Bujoczek, Lukasz Witek, Anita Olejek, Iwona Gabriel

{"title":"Expression of heat shock proteins HSPA1A, HSPA1B and TP53 in vulval lichen planus and vulval lichen sclerosus.","authors":"Adrianna Marzec, Aleksandra Augusciak-Duma, Dominika Kupny-Bujoczek, Lukasz Witek, Anita Olejek, Iwona Gabriel","doi":"10.5603/GP.a2023.0011","DOIUrl":"https://doi.org/10.5603/GP.a2023.0011","url":null,"abstract":"Objectives: Heat shock proteins (HSPs) are proteins involved in protein folding and maturation. HSP expression is induced by heat shock or other stressors including cellular damage and hypoxia. The major groups, which are classified based on their molecular weight, include HSP27, HSP40, HSP60, HSP70, HSP90, and large HSP (HSP110 and glucose-regulated protein 170). The comparison of heat shock proteins and TP53 expression is yet not well studied in both vulval lichen sclerosus and lichen planus. Our aim was to assess the HSP and TP53 gene expression in women suffering from LS or LP and compare it within these groups and also healthy controls.Material and methods: The inclusion criteria were willingness to donate vulval biopsies, not currently or in the prior two weeks received any local nor systemic treatment for vulval disorder, age > 18 years old. The exclusion criteria were lack of consent, current vaginal infection confirmed with microbiological studies, current local or systemic treatment for vulval disease. 45 consecutive women were recruited into the study. All appropriate vulval samples were process by genetic analysis.Results: The mean expression (± SD) of HPSA1A for controls was 5.52 ± 3.18, for LS was 7.44 ± 2.16 and for LP was 7.89 ± 2.48. The mean expression (± SD) of HPSA1B for controls was 6.54 ± 3.41, for LS was 9.94 ± 6.88 and for LP was 9.43 ± 2.31. The mean expression (± SD) of TP53 for controls was 9.11 ± 1.14, for LS was 9.94 ± 1.27 and for LP was 10.41 ± 2.00. HSPA1A expression was 3,8 higher in women with lichen sclerosus than in control group.Conclusions: Heat shock protein-70 is more often expressed in LS than in healthy controls. HSP-70 not only supports tumor growth and metastasis, but on the other hand mat help to develop immune-driven treatment strategies.","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9121324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Complications of planned home births in the Czech Republic. 捷克共和国计划在家分娩的并发症。

IF 1.3 4区医学

Ginekologia polska Pub Date : 2023-03-17 DOI: 10.5603/GP.a2023.0001

Petr Krepelka, Hynek Herman, Petr Velebil, Alena Mechurova, Jiri Hanacek, Zbynek Stranak, Jaroslav Feyereisl

{"title":"Complications of planned home births in the Czech Republic.","authors":"Petr Krepelka, Hynek Herman, Petr Velebil, Alena Mechurova, Jiri Hanacek, Zbynek Stranak, Jaroslav Feyereisl","doi":"10.5603/GP.a2023.0001","DOIUrl":"https://doi.org/10.5603/GP.a2023.0001","url":null,"abstract":"Objectives: This study evaluated complications that can occur during planned home births that require transfer to the hospital. These factors were assessed to improve the current status of deliveries performed outside health care facilities in the Czech Republic.Materials and methods: This prospective cohort study included data on 105 cases of complicated home births during 2017 to 2021 using an online form accessible to all hospital maternity wards in the Czech Republic.Results: Planned home births were complicated by fetal/neonatal causes, maternal causes, and combined fetomaternal complications in 28 (26.7%), 20 (19%), and 2 (1.9%) cases, respectively. The need for transfer was most often realized after the birth of the fetus (86; 81.9%); however, it was realized during birth in 19 (18.1%) cases. The following complications were noted most often: postpartum hemorrhage (23; 21.9%); neonatal asphyxia (17; 16.2); placental retention (14; 13.3%); birth injury (12; 11.4%); neonatal hypothermia (5; 4.8%); and placental birth (5; 4.8%). Indications for transfer during labor were as follows: labor obstruction (10; 9.5%); fetal hypoxia (5; 4.8%); bleeding during labor (2; 1.9%); preeclampsia (1; 0.9%); and fetal malformation (1; 0.9%). Perinatal death occurred in 8 (7.6%) cases. Permanent neonatal morbidity occurred in 4 (3.8%) cases.Conclusions: Patients with home birth complications were transferred to the hospital most often after the birth of the fetus. The low proportion of transfers during childbirth is caused by the unprofessional management of planned home births, resulting in a high number of perinatal deaths and high rate of permanent neonatal morbidity.","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9121331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of unilateral apical sling and laparoscopic sacrocolpopexy on the outcome in women with apical prolapse: randomised trial. 单侧根尖悬吊和腹腔镜骶colpop固定术对根尖脱垂女性患者预后的影响:随机试验。

IF 1.3 4区医学

Ginekologia polska Pub Date : 2023-03-17 DOI: 10.5603/GP.a2023.0002

Botagoz Aitbayeva, Serik Iskakov, Elena Lushchaeva, Galymzhan Toktarbekov, Kamilla Kenbayeva

{"title":"Effects of unilateral apical sling and laparoscopic sacrocolpopexy on the outcome in women with apical prolapse: randomised trial.","authors":"Botagoz Aitbayeva, Serik Iskakov, Elena Lushchaeva, Galymzhan Toktarbekov, Kamilla Kenbayeva","doi":"10.5603/GP.a2023.0002","DOIUrl":"https://doi.org/10.5603/GP.a2023.0002","url":null,"abstract":"Objectives: The purpose of this study was to compare the use of unilateral apical sling versus laparoscopic sacrocolpopexy in the treatment of the apical form of pelvic organ prolapse in women. M: aterial and methods:A prospective, single-center randomized trial included 100 patients who were alternately assigned to treatment. Each patient had a ≥ III stage of apical or anterior-apical prolapse determined by the POP-Q system. 45 accepted for unilateral apical sling (UAS)and 55 accepted for laparoscopic sacrocolpopexy (LS). Data were compared by the One-way ANOVA test using IBM SPSS stats 19.Results: Mean operating time was significantly greater in the LS group versus UAS group, 194.6 vs 42.4 minutes, respectively (p < 0.05). The amount of intraoperative bleeding was significantly higher in the UAS group, compared to the LS group (p = 0.01). Within the follow-up period, 2 patients in UAS group and 3 patients in LS group (4.4% vs 5.4%, respectively; p = 0.9) had recurrent cystocoele. HRQoL and sexual outcomes did not differ significantly between the two treatment groups.Conclusion: s:Our data demonstrate the non-superiority one on each other of the two different approaches, except in terms of shorter operating time and higher intraoperative bleeding when UAS used. These findings raise questions about the need for long-term results of quality of life outcomes for women with genital prolapse, especially in resource-limited settings similar to Kazakhstan.","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9121328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The analysis of the therapeutic decisions in a patient with gigantic ovarian leiomyoma. 对一名巨大卵巢卵母细胞瘤患者治疗决定的分析。

IF 1.3 4区医学

Ginekologia polska Pub Date : 2023-01-04 DOI: 10.5603/GP.a2022.0152

Tomasz Sylwestrzak, Jaroslaw Debniak, Dariusz Wydra, Tomasz Jastrzebski

引用次数: 0

The effect of hCG day progesterone in 1318 cycles on pregnancy outcomes: ongoing discussion. 1318 周期中 hCG 日黄体酮对妊娠结果的影响：持续讨论。

IF 1.2 4区医学

Ginekologia polska Pub Date : 2023-01-01 Epub Date: 2023-03-02 DOI: 10.5603/GP.a2022.0114

Özlem Kayacik Günday, Oya Aldemir, Runa Özelçi, Serdar Dilbaz, Emre Başer, Özlem Moraloğlu Tekin

{"title":"The effect of hCG day progesterone in 1318 cycles on pregnancy outcomes: ongoing discussion.","authors":"Özlem Kayacik Günday, Oya Aldemir, Runa Özelçi, Serdar Dilbaz, Emre Başer, Özlem Moraloğlu Tekin","doi":"10.5603/GP.a2022.0114","DOIUrl":"10.5603/GP.a2022.0114","url":null,"abstract":"Objectives: To investigate the effect of human chorionic gonadotropin day progesterone (hCG-P) level on pregnancy outcomes in in vitro fertilization (IVF) cycles.Material and methods: This study is an analysis of a cohort of 1318 fresh IVF- embryo transfer cycles, including 579 agonists and 739 antagonists, performed at a single IVF center between 2007 and 2018. For fresh cycles, we performed Receiver Operating Characteristic analysis (ROC) to calculate the threshold value of hCG-P, which affects pregnancy outcomes. We divided patients below and above the determined threshold value into two groups, then, correlation analysis and we performed logistic regression analysis.Results: According to ROC curve analysis of hCG-P, AUC was 0.537 (95% CI: 0.510-0.564, p < 0.05) for LBR, and the threshold value for P was 0.78. The hCG-P threshold value of 0.78 proved to be significant in relation to BMI, type of drug used during induction, the hCG day E2, the total number of oocytes, the number of oocytes and the subsequent pregnancy outcome between the two groups (p < 0.05). However, the model we built, which accounted for hCG-P, total number of oocytes, age, BMI, induction protocol, total dose of gonadotropin used in induction did not prove significant in terms of its effect on LBR.Conclusions: The threshold value of hCG-P that we found to have an effect on LBR was quite low compared with the p value generally recommended in the literature. Therefore, further studies are needed to determine an accurate p-value that reduces success in managing fresh cycles.","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":" ","pages":"616-624"},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9363631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anterior uterocervical angle: is it an ultrasonographic screening tool that estimates the latent phase duration in post term pregnancies? 子宫宫颈前角:它是一个超声筛查工具，估计潜伏期持续时间在足月后妊娠?

IF 1.2 4区医学

Ginekologia polska Pub Date : 2023-01-01 Epub Date: 2023-03-17 DOI: 10.5603/GP.a2022.0126

Nefise Nazli Yenigul, Fedi Ercan, Hakan Sager, Elif Yuce Bilgin, Emin Ustunyurt

{"title":"Anterior uterocervical angle: is it an ultrasonographic screening tool that estimates the latent phase duration in post term pregnancies?","authors":"Nefise Nazli Yenigul, Fedi Ercan, Hakan Sager, Elif Yuce Bilgin, Emin Ustunyurt","doi":"10.5603/GP.a2022.0126","DOIUrl":"10.5603/GP.a2022.0126","url":null,"abstract":"Objectives: In recent years, in addition to cervical length measurement, a new ultrasonographic parameter has been defined as uterocervical angle (UCA), which can be used in the prediction of preterm labor. In this study,we evaluated the place of uterocervical angle in predicting the latent phase duration in postterm pregnancies.Material and methods: This prospective study consists of 90 pregnant women aged between 18 to 40 years who were hospitalized with a diagnose of late term pregnancy. Pregnant women with a latent phase duration of 1200 minutes or less were defined as Group 1. Patients with latent phase duration over 1200 minutes were defined as Group 2. All patients' age, BMI, smoke, cervical length measurements, uterocervical angle, latent and active phase of labor durations, length of the third stage and delivery types were compared.Results: The UCA median value of group 1 was 120 (94-147), and group 2 was 99 (94-105) (p < 0.001). CL medians of Groups 1 and 2 were 29 (17-43) and 28 (27-41) respectively (p: 0.871). UCA (AUC: 0.917, p < 0.0001) significantly predicted prolonged latent phase duration. Optimal cut off value was obtained at the value of 105 degree (100% sensitivity, 75% specificity) for UCA. Kaplan-Meier survival analysis showed that duration of labor was significantly higher in a group with low UCA (p: 0.013).Conclusions: UCA can be a successful tool that can be used to predict duration of labor in cases of postterm pregnancies with medical induction.","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":" ","pages":"852-857"},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9121330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The nightmare of obstetricians - the placenta accreta spectrum in primiparous pregnant women. 产科医生的噩梦——初产孕妇的胎盘增生谱。

IF 1.3 4区医学

Ginekologia polska Pub Date : 2023-01-01 DOI: 10.5603/GP.a2022.0141

Ülkü Ayşe Türker Aras, Engin Korkmazer, Emin Üstünyurt

{"title":"The nightmare of obstetricians - the placenta accreta spectrum in primiparous pregnant women.","authors":"Ülkü Ayşe Türker Aras, Engin Korkmazer, Emin Üstünyurt","doi":"10.5603/GP.a2022.0141","DOIUrl":"https://doi.org/10.5603/GP.a2022.0141","url":null,"abstract":"Objectives: The incidence of PAS is increasing day by day as a life-threatening condition. The purpose of the present study was to determine the factors affecting PAS formation in primiparous pregnant women and to define possible risk factors for the mother and the baby.Material and methods: Bursa Yüksek İhtisas Training and Research Hospital, department of obstetrics and gynecology, Bursa, Turkey, between June 2016 and December 2020. A total of 58,895 patients were included in the study. After the exclusion criteria, the study was continued with 27 primiparous PAS and 54 non-primiparous PAS patients. The primary purpose is to evaluate PAS risk factors. The secondary aim is to examine maternal and neonatal characteristics.Results: When the parameters that are significant in terms of PAS risk factors were analyzed by Logistic Regression Analysis, it was found that the increase in age also increased the development of PAS 1.552 times (95% CI: 1.236-1.948) and a history of abortion was 7.928. times (95% CI: 1.408-44.654) and 11,007 times (95% CI: 2.059-58.832) with history of myomectomy; postoperative HB values (p < 0.001), an estimated amount of bleeding (p < 0.001), need for transfusion (p = 0.002), and use of drains ( < 0.001) were statistically significant different between two groups. When the neonatal results between patients with and without PAS were examined, birth weight (p < 0.001) and gestational week ( < 0.001) were statistically significant.Conclusions: PAS does not occur only in multiparous patients who have a history of previous cesarean section. It may also occur in primiparous patients and is a life-threatening condition.","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":"94 2","pages":"135-140"},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9278808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metastatic gastric cancer in a full-term pregnancy. 足月妊娠转移性胃癌。

IF 1.3 4区医学

Ginekologia polska Pub Date : 2023-01-01 DOI: 10.5603/GP.a2022.0159

Jorge Aparicio-Ponce, Sandra Salcedo-Hermoza, Sandra Aparicio-Salcedo, Gustavo Cerrillo, Carlos Nureña, Jose S Lazarte, Ericson L Gutierrez

引用次数: 0

A case of successful delivery after IVF-ET in a patient with a history of full-thickness uterine rupture and subsequent reconstructive surgery. 有全层子宫破裂及重建手术史的患者IVF-ET后成功分娩1例。

IF 1.3 4区医学

Ginekologia polska Pub Date : 2023-01-01 DOI: 10.5603/GP.a2022.0072

Monika Baczkowska, Artur Skowyra, Michal Ciebiera

{"title":"A case of successful delivery after IVF-ET in a patient with a history of full-thickness uterine rupture and subsequent reconstructive surgery.","authors":"Monika Baczkowska, Artur Skowyra, Michal Ciebiera","doi":"10.5603/GP.a2022.0072","DOIUrl":"https://doi.org/10.5603/GP.a2022.0072","url":null,"abstract":"Uterine rupture is a full-thickness uterine wall defect occurring during pregnancy. It is a rare but life-threatening condition for both the mother and the newborn. Myomectomy is a common gynecological procedure performed due to symptomatic uterine fibroids. The incidence of uterine rupture after myomectomy is estimated at < 1%. Our patient underwent laparoscopic myomectomy as a part of infertility treatment. After several unsuccessful IVF-ET attempts and dietary treatment a spontaneous pregnancy was confirmed in the patient. The pregnancy was uneventful until 36 weeks of pregnancy when the patient presented at the emergency department with abdominal pain. Emergency laparotomy was performed exposing extensive uterine rupture. The child did not survive, but, fortunately, uterus-sparing surgery was successful. Afterwards, due to the thinning of the uterine wall at the site of the postoperative scar, a reconstructive surgery was performed, resulting in a properly healed uterus six months after surgery. During the subsequent pregnancy the patient was admitted to the hospital at the 32nd week of pregnancy and an elective cesarean section was performed at 36 weeks of pregnancy. A healthy girl was born. The presented case draws attention to the importance of careful qualification for uterine surgeries in women of reproductive age and proper informing about the possible complications, as pregnancies after uterine surgeries come with new management challenges. Nonetheless, appropriate care may lead to the birth of a healthy child and delighted parents.","PeriodicalId":12727,"journal":{"name":"Ginekologia polska","volume":"94 4","pages":"339-340"},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10197912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0