Assessment of the birth status of children born by elective caesarean section before and after 39 weeks of gestation following in vitro fertilization.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Marek Pokulniewicz, Marcin Januszewski, Kamil Pluta, Alicja Jakimiuk, Tomasz Oleksik, Joanna Zytynska-Daniluk, Malgorzata Santor-Zaczynska, Artur Jakimiuk
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引用次数: 0

Abstract

The collected material presents 512 mothers with children whose pregnancies were ended by caesarean section at the Department of Obstetrics, Women's Diseases and Oncological Gynecology Central Clinical Hospital of the Ministry of Internal Affairs in Warsaw in the years 2004-2016. The study group consisted of 362 mothers in pregnancies following in vitro fertilization and 150 mothers in spontaneous pregnancy, without the use of assisted reproductive technology. For the purposes of the project, only single pregnancies ending within weeks 37 to 41 of pregnancy were selected. Planned delivery by elective cesarean section (ECS) currently takes place after the 39th week of pregnancy, in line with current common recommendations. This is related to studies finding an overall better birth condition of newborns in the general population, and especially regarding the maturation of the lungs. Currently, there are no specific recommendations regarding cesarean section and the timing of delivery in pregnancies resulting from in vitro fertilization. The aim of this study was to assess the optimal time of an elective cesarean section at full term in an IVF pregnancy. Consistent with findings in the general population and prevailing recommendations, the expected result would be the better condition of the baby born by ECS following the 39th week of gestation. However, our statistical analysis of the collected material shows that the group delivered by ECS prior to the end of 39 weeks of pregnancy may have fewer respiratory system interventions and higher Apgar scores. Nevertheless, results lack statistical significance. In conclusion these findings may indicate a need for a bigger database.

评估体外受精后在妊娠 39 周之前和之后选择剖腹产的婴儿的出生状况。
所收集的资料介绍了2004-2016年期间在华沙内务部中央临床医院产科、妇女病和肿瘤妇科通过剖腹产结束妊娠的512名有孩子的母亲的情况。研究小组由 362 名体外受精后怀孕的母亲和 150 名未使用辅助生殖技术自然怀孕的母亲组成。为了项目的目的,只选择了在怀孕第 37 至 41 周内结束的单胎妊娠。根据目前的普遍建议,选择性剖宫产(ECS)的计划分娩目前在妊娠第 39 周后进行。这与研究发现普通人群中新生儿的总体出生状况较好有关,尤其是在肺部成熟方面。目前,关于体外受精妊娠的剖宫产和分娩时间还没有具体的建议。本研究旨在评估试管婴儿妊娠足月时选择剖宫产的最佳时间。与一般人群的研究结果和普遍建议一致,预期的结果是在妊娠 39 周后进行选择性剖宫产的婴儿状况会更好。然而,我们对收集到的资料进行的统计分析显示,在妊娠 39 周结束前通过产前护理分娩的婴儿组可能呼吸系统干预较少,Apgar 评分较高。尽管如此,结果仍缺乏统计学意义。总之,这些发现可能表明需要一个更大的数据库。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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