Global Spine Journal最新文献

{"title":"Global Burden of Vertebral Fractures and Spinal Cord Injuries Due to Falls From 1990 to 2021: A Population-Based Study.","authors":"Tianyu Liu, Hanlin Zou, Haibo Zou","doi":"10.1177/21925682251331442","DOIUrl":"10.1177/21925682251331442","url":null,"abstract":"<p><p>Study DesignMeta-analysis-based calculation.ObjectivesFalls are the primary cause of vertebral fractures and spinal cord injuries (SCI). We aimed to analyze the burden and trends of vertebral fractures and SCI due to falls.MethodsWe extracted data on the incidence, prevalence, and years lived with disability (YLDs) of vertebral fractures and SCI due to falls in 21 regions and 204 countries. Estimated annual percentage changes and the Joinpoint regression analysis was used to assess time trends. And we used the Bayesian Age-Period-Cohort model to project the burden for the next 15 years. Then, We developed smoothed curve models and used Spearman's correlation coefficient to analyze the relationship between the Socio-Demographic Index (SDI) and the burden. Finally, frontier analysis was applied to evaluate the effective differences.ResultsIn 2021, there were 4.73 million new cases of vertebral fractures and 3.67 million prevalent cases, and SCI accounted for .3 million new cases and 6.94 million prevalent cases. Although age-standardized rates (ASRs) showed a declining trend, absolute case numbers increased by more than 50% since 1990. Middle-aged males and elderly females are more vulnerable. A positive correlation was found between SDI and ASRs (<i>P</i> < .001), with higher burdens in high SDI regions. Burdens continue to rise in low and middle SDI regions due to limited healthcare resources and development-related risks.ConclusionsThe global burden of vertebral fractures and SCI continues to grow. Prevention of falls and musculoskeletal degeneration is critical. Urgent action is needed to improve healthcare infrastructure and preventive measures.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251331442"},"PeriodicalIF":2.6,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11948242/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complications in Full-Endoscopic Posterior Cervical Surgery: A Review of the Literature and Preventive Strategies.","authors":"Vit Kotheeranurak, Pramod V Lokhande, Thanadol Tangdamrongtham, Teerachat Tassanasoomboon, Khanathip Jitpakdee, Weerasak Singhatanadgige, Worawat Limthongkul, Wicharn Yingsakmongkol, Yanting Liu, Jin-Sung Kim, Surachat Jaroenwareekul","doi":"10.1177/21925682251328615","DOIUrl":"10.1177/21925682251328615","url":null,"abstract":"<p><p>Study DesignNarrative reviewObjectivesFull-endoscopic cervical spinal surgery via a posterior approach has gained popularity for its effectiveness in treating various cervical spine pathologies. However, this technique presents its own set of complications that need to be recognized and addressed. This review aims to comprehensively analyze the complications associated with full-endoscopic posterior cervical spine surgery and provide preventive strategies to minimize these risks and ensure successful surgical outcomes.MethodsA thorough literature search was conducted using public databases, including PubMed and SCOPUS, from January 2000 to June 2024. The review focused on analyzing complications related to full-endoscopic posterior cervical spine surgery and identifying preventive strategies using the keywords \"Complication,\" \"Endoscopic,\" \"Full-endoscopic,\" \"Endoscopy,\" \"Uniportal,\" \"Biportal,\" \"Posterior,\" \"Cervical,\" \"Spine,\" \"Surgery,\" \"Foraminotomy,\" \"Decompression,\" and \"Discectomy\".ResultsThe review identified a variety of complications associated with full-endoscopic posterior cervical spine surgery, including neurological, vascular, and structural issues. Despite the minimally invasive benefits of this approach, risks such as nerve root injury, dural tears, and epidural hematomas still exist. The study emphasizes preventive strategies like meticulous preoperative planning, refined surgical techniques, and cautious intraoperative management around neural structures to mitigate these risks.ConclusionsWhile full-endoscopic posterior cervical spine surgery provides significant advantages, such as reduced tissue disruption and quicker recovery, it also carries specific complications that must be carefully addressed and managed. Prevention is crucial for ensuring optimal outcomes. By understanding potential risks and implementing effective prevention strategies, surgeons can significantly reduce complications and enhance patient safety.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251328615"},"PeriodicalIF":2.6,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11948246/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Early Heparin Prophylaxis and Risk of Venous Thromboembolism Through Two Months After Spine Fusion for Spinal Metastasis: A Retrospective Cohort Study of United States Academic Health Centers.","authors":"Anthony N Baumann, Robert J Trager, Omkar Anaspure, John T Strony, Aditya Muralidharan, Tyler Sanda, Jacob C Hoffmann","doi":"10.1177/21925682251330261","DOIUrl":"10.1177/21925682251330261","url":null,"abstract":"<p><p>Study DesignRetrospective Cohort Study.ObjectiveEvidence on chemoprophylactic anticoagulation efficacy in preventing venous thromboembolism (VTE) after spine surgery for metastasis is scarce. We hypothesized that early heparin administration (0-2 days post-surgery) significantly reduces VTE risk post-arthrodesis. We also examined VTE incidence and risk over 2 months and severe postoperative bleeding (SPOB).MethodsWe conducted a retrospective cohort study using the TriNetX network, identifying adults who had a spinal arthrodesis for spinal metastasis in the past 20 years. Patients were grouped by anticoagulation use: a heparin cohort and a non-anticoagulated control. After propensity matching for key VTE risk factors, we examined VTE risk ratios (RR) with 95% confidence intervals (CI) up to 2 weeks post-surgery, and incidence and RR of VTE and SPOB over 2 months.ResultsThere were 847 patients per cohort after matching. There was no statistically significant difference in incidence of VTE in the heparin group compared to the no anticoagulation cohort through 2-weeks' (4.0% vs 2.7%; RR: 1.48; 95% CI: 0.88, 2.49; <i>P</i> = 0.1383) and 2 months' follow-up (9.4% vs 7.9%; RR: 1.2; 95% CI: 0.88, 1.63; <i>P</i> = 0.2619). Furthermore, there was no statistically significant difference in incidence of SPOB in the heparin group compared to the no anticoagulation group at 2-weeks' (1.5% vs 1.7%; RR: 0.93; 95% CI: 0.44, 1.96; <i>P</i> = 0.8462) and 2-months' follow-up (2.8% vs 2.5%; RR: 1.1; 95% CI: 0.64, 2.04; <i>P</i> = 0.6504).ConclusionEarly heparin administration did not significantly affect VTE or SPOB rates compared to controls. Future research should explore whether other anticoagulants lower VTE risk post-spinal metastasis fusion.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251330261"},"PeriodicalIF":2.6,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11948240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of the AOSpine-DGOU Osteoporotic Fracture Classification - Effect of Surgical Experience, Surgical Specialty, Work-Setting and Trauma Center Level on Reliability and Reproducibility.","authors":"Julian Scherer, Sebastian Frederick Bigdon, Gaston Camino-Willhuber, Ulrich Spiegl, Andrei Fernandes Joaquim, Harvinder Singh Chhabra, Marcel Dvorak, Gregory Schroeder, Mohammad El-Sharkawi, Richard Bransford, Lorin Michael Benneker, Klaus John Schnake","doi":"10.1177/21925682251331945","DOIUrl":"10.1177/21925682251331945","url":null,"abstract":"<p><p>Study DesignCross-sectional survey.ObjectivesA cornerstone of classification systems is good reliability amongst different groups of classification users. Thus, the aim of this international validation study was to assess the reliability of the new AO Spine DGOU Osteoporotic Fracture Classification (OF classification) stratified by surgical specialty, work-setting, work-experience, and trauma center level.Methods320 spine surgeons were asked to rate 27 cases according to the OF classification at 2 time points, 4 weeks apart (assessment 1 and 2) in this online-webinar based validation process. The kappa statistic (κ) was calculated to assess the inter-observer reliability and the intra-rater reproducibility.ResultsA total of 7798 (90.3%) ratings were recorded in assessment 1 and 6621 (76.6%) ratings in assessment 2. Global inter-rater reliability was moderate in both assessments (κ = 0.57; κ = 0.58). Participants with a work-experience of >20 years showed the highest inter-rater agreement in both assessments globally (κ = 0.65; κ = 0.67). Participants from a level-1 trauma center showed the highest agreement (κ = 0.58), whereas participants working at a tertiary trauma center showed higher grade of agreement in the second assessment (κ = 0.66). Participants working in academia showed the highest agreement in assessment 2 (κ = 0.6). Surgeons with academic background and surgeons employed by a hospital showed substantial intra-rater agreement in the second assessment.ConclusionsThe AO Spine-DGOU Osteoporotic Fracture Classification showed moderate to substantial inter-rater agreement as well as intra-rater reproducibility regardless of work-setting, surgical experience, level of trauma center and surgical specialty.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251331945"},"PeriodicalIF":2.6,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11948244/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How to Reduce the Risk of Mechanical Failures in Adult Deformity Surgery: Comparing GAP Score and Roussouly Type Restoration.","authors":"Domenico Compagnone, Riccardo Cecchinato, Andrea Pezzi, Francesco Langella, Marco Damilano, Daniele Vanni, Andrea Redaelli, Claudio Lamartina, Pedro Berjano","doi":"10.1177/21925682251328285","DOIUrl":"10.1177/21925682251328285","url":null,"abstract":"<p><p>Study DesignRetrospective Cohort Study.ObjectivesTo assess long-term alignment descriptors correlating with mechanical complications.MethodsThe study included adult spinal deformity cases older than 18, with a minimum of four instrumented levels and a 5-year follow-up. Exclusions: previous spinal fusion, neuromuscular/rheumatic diseases, active infections, tumors, or incomplete radiographic exams. Collected data: demographic, surgical, pre- and post-operative spinopelvic parameters, and post-operative complications. The GAP score, original Roussouly type restoration, Schwab's criteria, and Odontoid to hip axis angle were evaluated using machine learning and logistic regression. Complications were evaluated with a Kaplan-Meier curve.ResultsTwo hundred and twelve patients fulfilled the inclusion and exclusion criteria and were enrolled in the study. The observed rate of revision surgery for mechanical complications was 40.6% (86 out of 212 patients). Higher post-operative GAP scores were associated with increased risks of revision for junctional failure (AUC = 0.72 [IC 95%] 0.62-0.80). The inability to restore the original Roussouly spinal shape was statistically associated with higher mechanical failure rates. A machine-learning approach and subsequent logistic regression found that the GAP score and original Roussouly type restoration are the most important predictors for mechanical failure, and GAP score lordosis distribution index and relative pelvic version are the most important factors to predict the risk of mechanical failure.ConclusionsIn our series, a proper post-operative GAP Score and the restoration of the original Roussouly type significantly minimize mechanical complication rates. We observed that junctional failure tends to occur earlier among complications, while implant failure occurs later in the follow-up.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251328285"},"PeriodicalIF":2.6,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11926813/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parameters Used to Define Horizonal Gaze: A Systematic Review.","authors":"Féthi Laouissat, Sonia Ramos-Pascual, Ankitha Kumble, Theo Broussolle, Danilo Casasola, Mo Saffarini, Alexis Nogier","doi":"10.1177/21925682251327128","DOIUrl":"10.1177/21925682251327128","url":null,"abstract":"<p><p>Study designSystematic review.ObjectiveTo summarise the parameters available to measure horizontal gaze, provide their values in patients and/or asymptomatic individuals, and assess their reliability.MethodsA literature search was conducted on 9/9/2023 using Medline and Embase, applying the following keywords: \"horizontal gaze\" or \"gaze line\". Articles that reported on horizontal gaze were included.ResultsTwenty-six articles published between 2015 and 2023, were included, of which 15 reported on patients, 10 reported on asymptomatic individuals, and one reported on both. The three most reported horizontal gaze parameters were McGregor's slope (n = 20 studies, asymptomatic individuals range: -8.8-10.2°), C0-C2 angle (n = 18 studies, asymptomatic individuals range: -32.0-101.5°), and chin brow vertical angle (CBVA) (n = 12 studies, asymptomatic individuals range: -5.9-12.7°). The most frequently reported correlations were between McGregor's slope and C0-C2 angle (R,-0.390-0.676; <i>P</i> < 0.065; n = 4 studies), McGregor's slope and CBVA (R, 0.679-0.862; <i>P</i> < 0.0001; n = 3 studies), as well as CBVA and slope of the line of sight (R, 0.592-0.996; <i>P</i> < 0.001; n = 3 studies).ConclusionThe present systematic review identified 18 parameters used to measure horizontal gaze; however, there is no gold standard. Although parameters had good to excellent inter-observer reliabilities, there were large variations in measurements among asymptomatic individuals across studies, which may imply a limited clinical relevance. Therefore, there is a need for a gold standard parameter of horizontal gaze, which uses easily identifiable landmarks that are simple to measure (reliable), relates both orbital and cervical anatomical structures, and provides insight into compensatory mechanisms in deformative or degenerative conditions.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251327128"},"PeriodicalIF":2.6,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Surgeon Demographic Factors in the Management of L4-5 Grade I Spondylolisthesis: A Survey by the AO Spine Knowledge Forum Degenerative.","authors":"Sathish Muthu, Samuel K Simister, Hania Shahzad, Hai Van Le, Luca Ambrosio, Stipe Corluka, Gianluca Vadala, Patrick C Hsieh, Michael Virk, Tim Yoon, Samuel K Cho, Ao Spine Knowledge Forum Degenerative","doi":"10.1177/21925682251324469","DOIUrl":"10.1177/21925682251324469","url":null,"abstract":"<p><p>Study DesignCross-sectional survey.ObjectiveWe explore the demographic factors amongst surgeons responsible for decision-making in the management of Grade I L4-5 degenerative lumbar spondylolisthesis(DLS).MethodsA survey presenting three clinical scenarios of DLS with varying degrees of neurological compression and instability was distributed to the AOSpine members globally to ascertain surgical management preferences. Management options such as decompression only or decompression and fusion and the techniques that would be employed were presented to the responders.ResultsAfter dissemination, 479 surgeons responded to the survey. Direct decompression was preferred for all three scenarios with and without neurologic deficits(82.5, 81.2, and 56.8%), with the majority favoring open procedures over minimally invasive or endoscopic procedures. Notably, younger, less experienced, and fellowship-trained surgeons showed a higher inclination toward minimally invasive and indirect decompression methods. A strong preference for surgical fusion over decompression(75.2, 92.5 and 86.6%, respectively) was also significantly observed, reflecting a general consensus on the need to achieve segmental stability.ConclusionThe results of this study demonstrate a pronounced preference for direct decompression and fusion among a group of global surgeons when treating L4-5 Grade I DLS across all demographics. This indicates a consensus on achieving decompression and stability; however, there are some trends indicating the impact of surgical management based on age, experience, and training of the treating providers. These findings suggest an evolution of surgical interventions toward less invasive techniques, particularly among younger surgeons, highlighting the need for global education to adopt innovative approaches in the management of DLS.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251324469"},"PeriodicalIF":2.6,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924050/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial Intelligence in Spinal Cord Injury Management: Comment.","authors":"Hinpetch Daungsupawong, Viroj Wiwanitkit","doi":"10.1177/21925682251328679","DOIUrl":"10.1177/21925682251328679","url":null,"abstract":"","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251328679"},"PeriodicalIF":2.6,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11915222/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143648300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MRI-Based Cervical VBQ Scores as Predictors of Cage Subsidence in Cervical Spine Surgery: A Meta-Analysis.","authors":"Song Wang, Hao Yang, Honglin Liao, Ping He, Xiang Zhang, Hao Liu, Bo Qu, Hongsheng Yang","doi":"10.1177/21925682251327381","DOIUrl":"10.1177/21925682251327381","url":null,"abstract":"<p><p>Study DesignSystematic review and meta-analysis.ObjectivePoor bone quality is a major risk factor for complications after cervical spine surgery. The MRI-based cervical vertebral bone quality (C-VBQ) score is a reliable tool for assessing bone quality. This study systematically evaluates, for the first time, the predictive value of C-VBQ for cage subsidence risk in cervical spine surgery patients using meta-analysis.MethodsWe conducted a comprehensive search of relevant literature in electronic databases up to October 16, 2024, to systematically assess the quality of included studies. Publication bias was evaluated by comparing C-VBQ between groups and calculating pooled sensitivity, specificity, and summary receiver operating characteristic (SROC) curves.Results7 studies involving 681 patients were included. Using the Quality Assessment of Diagnostic Accuracy Studies 2 (QUADAS-2) tool, the studies were deemed high quality with low risk of bias. High C-VBQ scores were significantly associated with fusion subsidence, with a pooled odds ratio of 2.98 (95% CI: 1.68-5.30). The C-VBQ cut-off value was 2.94 ± 0.32, and the combined sensitivity and specificity for diagnosing postoperative complications were 0.78 and 0.87, respectively, with an area under the curve of 0.90 (95% CI: 0.87-0.92).ConclusionIn patients undergoing degenerative cervical spine surgery, higher C-VBQ scores were significantly associated with an increased risk of cage subsidence. The C-VBQ score is a reliable tool for preoperative bone quality assessment and serves as an independent predictor of cage subsidence risk following cervical spine surgery.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251327381"},"PeriodicalIF":2.6,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910744/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Association Between Preoperative Cannabis Use and Anxiety, Pain Scores and Opioid Consumption in Patients Undergoing Spinal Fusion: A Retrospective Cohort Study.","authors":"Krizia Amoroso, Erika Chiapparelli, Jiaqi Zhu, Ali E Guven, Jennifer Shue, Andrew A Sama, Federico P Girardi, Frank P Cammisa, Alexander P Hughes, Ellen M Soffin","doi":"10.1177/21925682251327986","DOIUrl":"10.1177/21925682251327986","url":null,"abstract":"<p><p>Study DesignRetrospective cohort study.ObjectiveDespite increasing cannabis use, its prevalence in specific surgical groups is unclear, and its impact on perioperative care and outcomes is understudied. This study estimates cannabis use incidence in patients undergoing lumbar spine surgery and explores associations between preoperative use and anxiety, pain scores, and postoperative opioid consumption. We hypothesized a correlation between cannabis use and decreased reliance on opioids for postoperative pain relief.MethodsThis single-center retrospective cohort study included 204 patients undergoing single or multilevel spinal fusion surgery between July 2022 and August 2023. Self-reported cannabis use, demographics, surgical characteristics, numeric rating scale (NRS) pain scores, anxiety, inpatient opioid consumption, and discharge prescribing (total morphine equivalent dose) were extracted from electronic medical records (EMR). Patients were categorized into cannabis users or non-cannabis users, and group differences were analyzed using bivariable and multivariable regression.ResultsOf 204 patients, 27 (13.2%) were cannabis users and 177 (86.8%) were non-users. Cannabis users were younger (<i>P</i> = 0.007), more likely male (<i>P</i> = 0.028), and Caucasian (<i>P</i> = 0.032) than non-users. Preoperative cannabis use correlated significantly with anxiety disorder (<i>P</i> = 0.023) and higher preoperative (<i>P</i> = 0.016) and postoperative (<i>P</i> = 0.002) NRS pain scores. Multivariable analysis showed cannabis use associated with higher preoperative (<i>P</i> = 0.015) but not postoperative (<i>P</i> = 0.073) pain scores. No significant differences were found in preoperative, discharge opioid prescribing or postoperative opioid consumption.ConclusionThe incidence of cannabis use was low, but positively associated with anxiety and higher preoperative NRS pain scores. Large, well-powered trials are needed to understand cannabis's impact on spine surgery outcomes.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251327986"},"PeriodicalIF":2.6,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910729/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}