Global Spine JournalPub Date : 2025-05-01Epub Date: 2024-09-02DOI: 10.1177/21925682241282275
Jian Cui, Jingjing Zhang, Wenzhe Li, Wei Liu, Yixi Wang, Tao Xu, Yi Wang, Xiangyou Yu
{"title":"Analyzing Risk Factors for Delayed Extubation Following Posterior Approach Surgery for Congenital Scoliosis: A Retrospective Cohort Study.","authors":"Jian Cui, Jingjing Zhang, Wenzhe Li, Wei Liu, Yixi Wang, Tao Xu, Yi Wang, Xiangyou Yu","doi":"10.1177/21925682241282275","DOIUrl":"10.1177/21925682241282275","url":null,"abstract":"<p><p>Study DesignRetrospective cohort study.ObjectivesInvestigate the risk factors for delayed extubation after posterior approach orthopedic surgery in patients with congenital scoliosis.MethodsThe clinical data of patients who received surgery for congenital scoliosis at the First Affiliated Hospital of Xinjiang Medical University between January 2021 and July 2023 have been gathered. Patients are categorized into the usual and the delayed extubation groups, depending on the duration of tracheal intubation after surgery. The study employs univariate and multivariate logistic regression models to examine the clinical characteristics of the two cohorts and discover potential risk factors linked to delayed extubation. In addition, a prediction model is created to visually depict the significance of each risk factor in terms of weight according to the nomogram.ResultsA total of 119 patients (74.8% females), with a median age of 15 years, are included. A total of 32 patients, accounting for 26.9% of the sample, encountered delayed extubation. Additionally, 13 patients (10.9%) suffered perioperative complications, with pneumonia being the most prevalent. The multivariate regression analysis revealed that the number of osteotomy segments, postoperative hematocrit, postoperative Interleukin-6 levels, and weight are predictive risk factors for delayed extubation.ConclusionsPostoperative hematocrit and Interleukin-6 level, weight, and number of osteotomy segments can serve as independent risk factors for predicting delayed extubation, with combined value to assist clinicians in evaluating the risk of delayed extubation of postoperative congenital scoliosis patients, improving the success rate of extubation, and reducing postoperative treatment time in the intensive care unit.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"2051-2061"},"PeriodicalIF":2.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11571709/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142119528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Global Spine JournalPub Date : 2025-05-01Epub Date: 2024-08-21DOI: 10.1177/21925682241278323
Anthony L Mikula, Laurence D Rhines, Shalin S Patel, Zach Pennington, S Mohammed Karim, Jonathan M Morris, Karthik Tappa, Christopher Alvarez-Breckenridge, Robert Y North, Claudio E Tatsui, Peter S Rose, Michelle J Clarke, Justin E Bird
{"title":"Utility of 3D-Printed Models in the Surgical Planning for Primary Spine Tumors: A Survey of International Spinal Oncology Experts.","authors":"Anthony L Mikula, Laurence D Rhines, Shalin S Patel, Zach Pennington, S Mohammed Karim, Jonathan M Morris, Karthik Tappa, Christopher Alvarez-Breckenridge, Robert Y North, Claudio E Tatsui, Peter S Rose, Michelle J Clarke, Justin E Bird","doi":"10.1177/21925682241278323","DOIUrl":"10.1177/21925682241278323","url":null,"abstract":"<p><p>Study DesignSurvey study.ObjectivesThe purpose of this study was to characterize the utility of 3D printed patient specific anatomic models for the planning of complex primary spine tumor surgeries.MethodsA survey of individual members of an international study group of spinal oncology surgeons was performed. Participants were provided a clinical vignette, pathologic diagnosis, and pre-operative imaging for three primary spinal oncology cases. Study participants provided a free text surgical plan for resection and were then presented an associated 3D printed model for each case and asked to re-evaluate their surgical plan.ResultsTen spinal oncology surgeons participated in the study, representing nine institutions across five countries. Four of the surgeons (40%) made significant changes to their surgical plan after reviewing the 3D models, including sacrifice of an additional nerve root to obtain negative margins, sparing an SI joint that was originally planned for inclusion in the en bloc resection, adjusting the location of osteotomy cuts, changes to the number of surgical stages and/or staging order, and preservation of neurology that was originally planned for sacrifice. The overall impression of the 3D models was positive, with 90% of the participants stating they found the 3D model useful in developing a surgical plan.ConclusionsSurgical planning for resection of primary spinal column tumors is challenging and time intensive. 3D printed patient specific surgical models may be an additional tool that can augment surgical planning and execution by improving the chance of accomplishing surgical resection goals and minimizing morbidity.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"2004-2013"},"PeriodicalIF":2.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11571598/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142016915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Global Spine JournalPub Date : 2025-05-01Epub Date: 2024-08-31DOI: 10.1177/21925682241280258
Ningning Feng, Wenhao Li, Xing Yu, He Zhao, Ziye Qiu, Jianbin Guan, Guozheng Jiang, Kaitan Yang
{"title":"Cervical Vertebra Bone Quality Score Predicts Zero-Profile Anchored Spacer Interbody Fusion Cage Subsidence after Anterior Cervical Diskectomy and Fusion: A Retrospective Study.","authors":"Ningning Feng, Wenhao Li, Xing Yu, He Zhao, Ziye Qiu, Jianbin Guan, Guozheng Jiang, Kaitan Yang","doi":"10.1177/21925682241280258","DOIUrl":"10.1177/21925682241280258","url":null,"abstract":"<p><p>Study DesignRetrospective study.ObjectiveThis retrospective study primary focus is to investigate the relationship between the C-VBQ score and the occurrence of postoperative zero-profile anchored spacer (ROI-C) interbody fusion cage subsidence. Additionally, we aim to evaluate the predictive efficacy of the C-VBQ scoring system for subsidence in the context of ACDF with the ROI-C.MethodsPatients who underwent ACDF with the ROI-C cage at our hospital between January 2016 and December 2022 were included in this study. Univariate analysis and multivariate logistic regression were employed to identify independent risk factors associated with ROI-C cage subsidence after ACDF. Pearson correlation analysis was utilized to assess the correlation between the C-VBQ score and the height of ROI-C cage subsidence.ResultsA total of 102 patients underwent ACDF with ROI-C in our hospital were included in this study. Univariate analysis showed that age (<i>P</i> = 0.021) and C-VBQ score (<i>P</i> < 0.001) were the influencing factors of cage subsidence. Pearson correlation analysis showed that there was a significant positive correlation between the subsidence height of ROI-C cage and C-VBQ (r = 0.55, <i>P</i> < 0.01). Multivariate binary logistic regression analysis showed that C-VBQ score was the only variable that could significantly predict the subsidence of ROI-C cage after ACDF. Higher C-VBQ score was significantly associated with cage subsidence (<i>P</i> < 0.001).The AUC was 0.89, and the cutoff value for C-VBQ was 2.70.ConclusionThe findings indicate a significant correlation between a higher C-VBQ score before surgery and ROI-C cage subsidence after ACDF. The preoperative assessment of C-VBQ proves valuable for clinicians, enabling them to identify patients with low bone mineral density and predict the risk of zero-profile anchored spacer interbody fusion cage subsidence following ACDF.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"2020-2031"},"PeriodicalIF":2.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11571383/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142106602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Global Spine JournalPub Date : 2025-05-01Epub Date: 2024-12-05DOI: 10.1177/21925682241307634
Juan Álvarez de Mon-Montoliú, Juan Castro-Toral, César Bonome-González, Manuel González-Murillo
{"title":"Meta-Analysis of Learning Curve in Endoscopic Spinal Surgery: Impact on Surgical Outcomes.","authors":"Juan Álvarez de Mon-Montoliú, Juan Castro-Toral, César Bonome-González, Manuel González-Murillo","doi":"10.1177/21925682241307634","DOIUrl":"10.1177/21925682241307634","url":null,"abstract":"<p><p>Study DesignSystematic review and meta-analysis.ObjectiveThis meta-analysis aimed to evaluate the learning curve in endoscopic spinal surgery, including the time to mastery and challenges faced by novice surgeons, to improve learning and surgical outcomes.MethodsData extraction included the learning curve period and a comparison of surgeons with more experience or late period of the learning curve (late) and surgeons with less experience and in the early period of the learning curve (early) with respect to demographic, surgical, hospitalization, functional, and complication variables. Statistical analysis was performed using Review Manager 5.4.1 software.ResultsThis meta-analysis included 16 studies (n = 1902). The average number of cases required to reach the learning curve was 32.5 ± 10.5. The uniportal technique required fewer cases (30.1 ± 10.2) than biportal technique (38.7 ± 10.3). There were no significant differences in demographic variables, operation level, or duration of symptoms between the advanced and novice surgeons. Advanced surgeons showed better outcomes in VAS leg pain at less than 6 months (SMD 0.18, 95% CI 0.01-0.34) and >6 months (SMD 0.14, 95% CI 0.02-0.27), as well as VAS back pain at > 6 months (SMD 0.16, 95% CI 0.04-0.29). The incidence of total complications was significantly higher in the novice surgeon group. The specific complications did not differ significantly between the 2 groups.ConclusionsThe average number of cases required to reach the learning curve was 32.5 ± 10.5. Experienced surgeons had shorter surgery and fluoroscopy times, better outcomes in leg and back pain, and a lower incidence of complications than novice surgeons.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"2500-2513"},"PeriodicalIF":2.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622208/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142784919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Global Spine JournalPub Date : 2025-05-01Epub Date: 2024-11-19DOI: 10.1177/21925682241300977
Omar Ramos, Benjamin Mueller, Amir Mehbod, Bayard Carlson
{"title":"Outcomes and Complications After Elective Thoracic and Lumbar Spinal Fusion in Elderly Patients: A Comparison of Methods to Predict Adverse Events.","authors":"Omar Ramos, Benjamin Mueller, Amir Mehbod, Bayard Carlson","doi":"10.1177/21925682241300977","DOIUrl":"10.1177/21925682241300977","url":null,"abstract":"<p><p>Study DesignRetrospective study.ObjectivesThe current study compares the ability of the modified Frailty Index (mFI), the American Society of Anesthesiologists (ASA) classification, the modified Charleston Comorbidity Index (mCCI), the American College of Surgeons Surgical Risk Calculator (SRC), and the Fusion Risk Score (FRS) to predict perioperative outcomes.MethodsComorbidity indices were calculated for patients undergoing elective thoracic and lumbar spinal fusion at a single institution and assessed for their discriminative ability in predicting the desired outcomes using an area under the curve (AUC) analysis.Results393 patients met the inclusion and exclusion criteria. Patients being treated for adult spinal deformity (ASD) had the highest rate of complications (44.4%). The FRS had acceptable discrimination (AUC >0.7) and the highest ability among the methods studied to predict any adverse effects, new neurological deficit, return to OR within 90 days, and surgical site infection. It had good discrimination ability (AUC >0.8) predicting durotomy, respiratory failure (RF) requiring intubation, hemodynamic instability, and sepsis. The SRC had acceptable discrimination and highest ability to predict deep venous thrombosis (DVT). The mCCI had excellent and the highest ability to predict acute renal failure (ARF). For the other outcomes, the indices had either poor predictive ability (AUC 0.6-0.7) or no discriminative ability (AUC <0.6).ConclusionsThe FRS had a better ability than the ASA, mCCI, mFI, and SRC to predict the most perioperative adverse events and reoperation. Further study is needed to develop preoperative indices with better predictive ability of postoperative outcomes.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"2384-2399"},"PeriodicalIF":2.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11577552/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Global Spine JournalPub Date : 2025-05-01Epub Date: 2024-11-10DOI: 10.1177/21925682241301049
Jamie Brannigan, Sundar K Vellaiyappan, Oliver D Mowforth, Joseph Magee, Jibin J Francis, Benjamin M Davies, Mark R Kotter
{"title":"Outcomes for Degenerative Cervical Myelopathy Following Implementation of the AO Spine International Guidelines: A Single-Centre Service Evaluation.","authors":"Jamie Brannigan, Sundar K Vellaiyappan, Oliver D Mowforth, Joseph Magee, Jibin J Francis, Benjamin M Davies, Mark R Kotter","doi":"10.1177/21925682241301049","DOIUrl":"10.1177/21925682241301049","url":null,"abstract":"<p><p>IntroductionDegenerative cervical myelopathy (DCM) is a syndrome of symptomatic cervical spinal cord compression due to degenerative spinal changes. Until recently there was no formal consensus on exactly which patients are suitable for surgical or conservative management. The AO Spine international guidelines were introduced to address this issue, based on the best available current evidence. However, their implementation into routine clinical practice has not yet been reported. The objective was to evaluate surgical outcomes following the implementation of the AO Spine guidelines at our spinal neurosurgical centre.MethodsA service evaluation was conducted using data collected from electronic healthcare records for 259 patients, with outcomes of interest including change in mJOA score and complications. Data from 193 patients were included in the final analysis.ResultsThere was a mean improvement of the mJOA score by 1.53 points, 1.44 point and 1.92 points at post-operative intervals of 3 months (<i>P</i> < .001), 6 months (<i>P</i> < .001) and 12 months (<i>P</i> < .001). The percentage (number) of patients whose increase in mJOA score was greater than or equal to the minimal clinically importance difference (MCID) was 41% (44/107), 34% (33/96) and 43% (49/114) at these respective time intervals. Intraoperative complications occurred in 28 patients (11.7%). No association was found between BMI and postoperative change in mJOA score.ConclusionOur results are comparable to those from best practice data and suggest adherence to international guidelines provides a service that promotes meaningful recovery for patients with DCM. Therefore, our results offer support for implementation of the AO Spine international guidelines in clinical practice.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"2400-2408"},"PeriodicalIF":2.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11561916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142618657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Global Spine JournalPub Date : 2025-05-01Epub Date: 2025-02-20DOI: 10.1177/21925682251322592
Bo-Tao Cai, Fan Yang, Deng-Chao Wang
{"title":"Letter to the Editor: Is Endoscopic Surgery a Safe and Effective Treatment for Lumbar Disc Herniation? A Meta-Analysis of Randomized Controlled Trials.","authors":"Bo-Tao Cai, Fan Yang, Deng-Chao Wang","doi":"10.1177/21925682251322592","DOIUrl":"10.1177/21925682251322592","url":null,"abstract":"","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"2572-2573"},"PeriodicalIF":2.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11843560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143457593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Global Spine JournalPub Date : 2025-05-01Epub Date: 2025-01-27DOI: 10.1177/21925682251316544
Hongyu Chen, Yu Sun, Feifei Zhou
{"title":"Letter re: \"Are Variable Screw Angle Change and Screw-To-Vertebral Body Ratio Associated with Radiographic Subsidence Following Anterior Cervical Discectomy and Fusion?\"","authors":"Hongyu Chen, Yu Sun, Feifei Zhou","doi":"10.1177/21925682251316544","DOIUrl":"10.1177/21925682251316544","url":null,"abstract":"","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"2564-2565"},"PeriodicalIF":2.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11773500/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Global Spine JournalPub Date : 2025-05-01Epub Date: 2024-11-10DOI: 10.1177/21925682241300269
Alina Jacob, Christian R Wirtz, Markus Loibl, Stefan Kruger, Benjamin H Blankson, Robert N Dunn, Nicholas A Kruger
{"title":"Predictors of Early Mortality After Traumatic Spinal Cord Injury in South Africa.","authors":"Alina Jacob, Christian R Wirtz, Markus Loibl, Stefan Kruger, Benjamin H Blankson, Robert N Dunn, Nicholas A Kruger","doi":"10.1177/21925682241300269","DOIUrl":"10.1177/21925682241300269","url":null,"abstract":"<p><p>Study DesignRetrospective cohort study.ObjectivesTo identify predictors for early mortality following traumatic spinal cord injury (TSCI), as recognition of factors associated with early mortality is essential for public resource allocation and optimized acute care.MethodsRetrospective Analysis of SCI patients admitted to the acute SCI ward from 2003 to 2022 was performed. Days elapsing from the date of injury to date of death established the survival time. Early mortality was defined as survival time ≤ 365 days. Multivariable logistic regression was used in modeling of early death following TSCI with age, gender, neurologic deficit, type of neurologic injury, ventilation status, and count of complications as covariates.ResultsSimple logistic regression indicated a significant association of early mortality with the number of complications (<i>P</i> < .0001), neurological deficit (<i>P</i> < .0001), complete neurological injury (<i>P</i> < .0001), ventilation status (<i>P</i> < .0001), and age group (<i>P</i> < .0003). After adjusting for other covariates, complete neurological injury (OR: 1.75, <i>P</i> < .0001), ventilation (OR: 2.80, <i>P</i> < .0001), and Age group (over 60 OR: 17.71, <i>P</i> < .0001) were significantly associated with early mortality. The multivariable model showed a good overall fit (Hosmer-Lemeshow <i>P</i> = .315; AUC 0.85).ConclusionsPredictors of early mortality after TSCI are high complete spinal cord injury, age, number of complications, and the need for ventilation. Identification of high-risk patients is crucial to rationalize and improve acute care to potentially reduce mortality rates.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"2359-2366"},"PeriodicalIF":2.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11561959/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142618659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}