Global Spine Journal最新文献_第9页

From Modic to Disc Endplate Bone Marrow Complex - The Natural Course and Clinical Implication of Vertebral Endplate Changes. 从 Modic 到椎间盘终板骨髓复合体 - 椎骨终板变化的自然过程和临床意义。

IF 2.6 3区医学

Global Spine Journal Pub Date : 2024-08-01 DOI: 10.1177/21925682241271440

Shanmuganathan Rajasekaran, Karthik Ramachandran, Sri Vijay Anand K S, Rishi M Kanna, Ajoy P Shetty

{"title":"From Modic to Disc Endplate Bone Marrow Complex - The Natural Course and Clinical Implication of Vertebral Endplate Changes.","authors":"Shanmuganathan Rajasekaran, Karthik Ramachandran, Sri Vijay Anand K S, Rishi M Kanna, Ajoy P Shetty","doi":"10.1177/21925682241271440","DOIUrl":"https://doi.org/10.1177/21925682241271440","url":null,"abstract":"Study design: Review article.Objectives: A review of literature on the epidemiology, natural course, pathobiology and clinical implications of vertebral endplate changes.Methods: A literature search was performed using the Cochrane Database of Systematic Reviews, EMBASE, and PubMed. Studies published over the last 10 years were analysed. The searches were performed using Medical Subject Headings terms, and the subheadings used were \"Vertebral endplate changes\", \"Modic changes\", \"Disc Endplate Bone Marrow complex\".Results: The disc, endplate (EP), and bone marrow region of the spine constitute a unified morphological and functional unit, with isolated degeneration of any one structure being uncommon. Disc degeneration causes endplate defects, which result in direct communication and a constant cross-talk between the disc and the vertebral body. This may result in a persistent inflammatory state of the vertebral bone marrow, serving as a major pain generator. This review article focuses on vertebral endplate changes and how the current understanding has progressed from the Modic classification to the Disc Endplate Bone Marrow complex classification. It provides a clear portrayal of the natural course of these alterations and their clinical implications in low back pain.Conclusions: In light of the heightened interest and current prominence of vertebral endplate changes within the spine community, we must progress beyond the Modic changes to achieve a comprehensive understanding. The DEBM complex classification will play a major part in disc degeneration research and clinical care, representing a considerable advancement in our understanding of the vertebral endplate changes over the classical Modic changes.","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141874627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Shape and Size of the Annulus Fibrosus Excision Alters the Biomechanics of the Intervertebral Disc. 纤维环切除的形状和大小改变了椎间盘的生物力学。

IF 2.6 3区医学

Global Spine Journal Pub Date : 2024-07-30 DOI: 10.1177/21925682241270090

Mao-Dan Nie, Ze-Bin Huang, Rong-Shan Cheng, Qiang Zhang, Ji-Ping Zhang, Ling-Jie Fu, Cheng-Kung Cheng

{"title":"Shape and Size of the Annulus Fibrosus Excision Alters the Biomechanics of the Intervertebral Disc.","authors":"Mao-Dan Nie, Ze-Bin Huang, Rong-Shan Cheng, Qiang Zhang, Ji-Ping Zhang, Ling-Jie Fu, Cheng-Kung Cheng","doi":"10.1177/21925682241270090","DOIUrl":"https://doi.org/10.1177/21925682241270090","url":null,"abstract":"Study design: Biomechanical testings and finite element analysis.Objectives: This study aims to investigate how annulus fibrosus (AF) incision size (RIS, Ratio of incision width to AF height) and shape affect intervertebral disc (IVD) biomechanics.Methods: A validated finite element model of lumbar spines simulated various incisions in the middle-right posterior region of the AF, with different sizes and shapes. Simulations included axial compression, flexion, extension, bending, and rotation. Parameters assessed included stability, re-herniation, and IVD degeneration by analyzing stress, height, Intradiscal pressure (IDP), and the range of motion (ROM).Results: Incision increased AF stress and ROM under 3 Nm moment, with values rising as RIS increased. RIS exceeding 40% resulted in a 20% AF stress increase during compression and extension, while RIS over 50% led to over 20% AF stress increase during other motions. Incision stress also increased with higher RIS, particularly surpassing 50% RIS. IDP rose across all incision shapes. Endplate stress increased (9.9%-48.9%) with larger incisions, with average increases of 12.8%, 12.7%, 30.5%, and 22.8% for circular, oval, square, and rectangular incisions. Compression and rotation minimally affected NP pressure (<15%), while flexion (19.8%-38.8%) and bending (18.5%-43.9%) had a more pronounced effect. ROM increased with RIS (20.0% ∼ 77.4%), especially with an incision RIS exceeding 40%.Conclusions: AF injury elevates AF stress, reduces spine stability, heightens degeneration risk with increasing RIS. Reherniation risk rises when RIS exceeds 40%. Circular or oval incisions maintain spine biomechanics better than square or rectangular ones.","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141855335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management of Metastatic Spinal Disease - A Practical Approach. 转移性脊柱疾病的治疗--实用方法。

IF 2.6 3区医学

Global Spine Journal Pub Date : 2024-07-28 DOI: 10.1177/21925682231173646

Graham Ka Hon Shea, Kenny Yat Hong Kwan

引用次数: 0

Advances in Surgery for Metastatic Disease of the Spine: An Update for Oncologists. 脊柱转移性疾病的手术治疗进展：肿瘤学家的最新进展

IF 2.6 3区医学

Global Spine Journal Pub Date : 2024-07-28 DOI: 10.1177/21925682231155847

Chien Yew Kow, Mendel Castle-Kirszbaum, Jeremy Kt Kam, Tony Goldschlager

{"title":"Advances in Surgery for Metastatic Disease of the Spine: An Update for Oncologists.","authors":"Chien Yew Kow, Mendel Castle-Kirszbaum, Jeremy Kt Kam, Tony Goldschlager","doi":"10.1177/21925682231155847","DOIUrl":"https://doi.org/10.1177/21925682231155847","url":null,"abstract":"Study design: Narrative review.Objective: Metastatic spine disease is an increasingly common clinical challenge that requires individualised multidisciplinary care from spine surgeons and oncologists. In this article, the authors describe the recent surgical advances in patients presenting with spinal metastases.Methods: We present an overview of the presentation, assessment, and management of spinal metastases from the perspective of the spine surgeon, highlighting advances in surgical technology and techniques, to facilitate multidisciplinary care for this complex patient group. Neither institutional review board approval nor patient consent was needed for this review.Results: Advances in radiotherapy delivery and systemic therapy (including immunotherapy and targeted therapy) have refined operative indications for decompression of neural structures and spinal stabilisation, while advances in surgical technology and technique enable these goals to be achieved with reduced morbidity. Formulating individualised management strategies that optimise outcome, while meeting patient goals and expectations, requires a comprehensive understanding of the factors important to patient management.Conclusion: Spinal metastases require prompt diagnosis and expert management by a multidisciplinary team. Improvements in systemic, radiation, and surgical therapies have broadened operative indications and increased operative candidacy, and future advances are likely to continue this trend.","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141787805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Classically and Machine Learning Generated Survival Prediction Models for Patients With Spinal Metastasis - A meta-Analysis of Two Recently Developed Algorithms. 脊柱转移患者的经典生存预测模型与机器学习生成的生存预测模型的比较--对最近开发的两种算法的元分析。

IF 2.6 3区医学

Global Spine Journal Pub Date : 2024-07-28 DOI: 10.1177/21925682231162817

Hung-Kuan Yen, Wei-Hsin Lin, Olivier Quinten Groot, Chih-Wei Chen, Jiun-Jen Yang, Michiel Erik Reinier Bongers, Aditya Karhade, Akash Shah, Tse-Chuan Yang, Bas Jj Bindels, Shih-Hsiang Dai, Jorrit-Jan Verlaan, Joseph Schwab, Shu-Hua Yang, Francis J Hornicek, Ming-Hsiao Hu

{"title":"Comparison of Classically and Machine Learning Generated Survival Prediction Models for Patients With Spinal Metastasis - A meta-Analysis of Two Recently Developed Algorithms.","authors":"Hung-Kuan Yen, Wei-Hsin Lin, Olivier Quinten Groot, Chih-Wei Chen, Jiun-Jen Yang, Michiel Erik Reinier Bongers, Aditya Karhade, Akash Shah, Tse-Chuan Yang, Bas Jj Bindels, Shih-Hsiang Dai, Jorrit-Jan Verlaan, Joseph Schwab, Shu-Hua Yang, Francis J Hornicek, Ming-Hsiao Hu","doi":"10.1177/21925682231162817","DOIUrl":"https://doi.org/10.1177/21925682231162817","url":null,"abstract":"Study design: A systemic review and a meta-analysis. We also provided a retrospective cohort for validation in this study.Objective: (1) Using a meta-analysis to determine the pooled discriminatory ability of The Skeletal Oncology Research Group (SORG) classical algorithm (CA) and machine learning algorithms (MLA); and (2) test the hypothesis that SORG-CA has less variability in performance than SORG-MLA in non-American validation cohorts as SORG-CA does not incorporates regional-specific variables such as body mass index as input.Methods: After data extraction from the included studies, logit-transformation was applied for extracted AUCs for further analysis. The discriminatory abilities of both algorithms were directly compared by their logit (AUC)s. Further subgroup analysis by region (America vs non-America) was also conducted by comparing the corresponding logit (AUC).Results: The pooled logit (AUC)s of 90-day SORG-CA was .82 (95% confidence interval [CI], .53-.11), 1-year SORG-CA was 1.11 (95% CI, .74-1.48), 90-day SORG-MLA was 1.36 (95% CI, 1.09-1.63), and 1-year SORG-MLA was 1.57 (95% CI, 1.17-1.98). All the algorithms performed better in United States than in Taiwan (P < .001). The performance of SORG-CA was less influenced by a non-American cohort than SORG-MLA.Conclusion: These observations might highlight the importance of incorporating region-specific variables into existing models to make them generalizable to racially or geographically distinct regions.","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141787806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Magnetic Resonance Imaging of the Psoas Muscle Area as the Prognostic Factor for Survival and Adverse Events in Spinal Metastasis Surgery. 作为脊柱转移手术生存率和不良事件预后因素的腰肌区磁共振成像研究

IF 2.6 3区医学

Global Spine Journal Pub Date : 2024-07-28 DOI: 10.1177/21925682231173366

Kitidate Boonchai, Borriwat Santipas, Sirichai Wilartratsami, Monchai Ruangchainikom, Ekkapoj Korwutthikulrangsri, Pawin Akkarawanit, Panya Luksanapruksa

{"title":"The Magnetic Resonance Imaging of the Psoas Muscle Area as the Prognostic Factor for Survival and Adverse Events in Spinal Metastasis Surgery.","authors":"Kitidate Boonchai, Borriwat Santipas, Sirichai Wilartratsami, Monchai Ruangchainikom, Ekkapoj Korwutthikulrangsri, Pawin Akkarawanit, Panya Luksanapruksa","doi":"10.1177/21925682231173366","DOIUrl":"https://doi.org/10.1177/21925682231173366","url":null,"abstract":"Study design: Retrospective study.Objective: This study aimed to evaluate the ability of the mortality and adverse events prediction following metastatic spinal surgery of MRI-based cross-sectional psoas muscle area (PMA).Methods: A retrospective chart review, 120 patients who had undergone metastatic spinal surgery were included. The cross-sectional area identified the PMA under MR-imaging at the L3 or L4 pedicle level, which was classified into 3 tertiles. We used univariate and multivariate cox proportional hazard regression to assess whether PMA was associated with 30-day, 90-day, 1-year, and overall mortality.Results: The small psoas tertile group populations had a higher mortality rate than the large psoas tertile group. PMA in T1 and T2 had a probability of a higher 90-d mortality rate than PMA in T3 (T1 VS T3: P = .29 and T2 VS T3: P = .12). The median survival time was 7 months, 9 months, and 10 months in PMA T1, T2, and T3, respectively. PMA in tertile 2 had a significantly higher mortality rate of 38% compared to PMA in tertile 3 (HR 1.38, 95% CI .83-2.32, P = .02). Considering PMA as a continuous variable, every 1 mm2 increment of PMA resulted in the increase survivorship of 1% (HR .99 with 95% CI .99-1).Conclusion: The MRI-based cross-sectional PMA tends to predict the 90-d mortality rate and overall mortality rate in spinal metastasis patients who underwent spinal surgery. The PMA should be considered one of the prognostic factors in the treatment of metastatic spinal patients.","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141787809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inflammatory Bowel Disease as a Risk Factor for Complications and Revisions Following Lumbar Discectomy. 炎症性肠病是腰椎间盘切除术后并发症和翻修的风险因素。

IF 2.6 3区医学

Global Spine Journal Pub Date : 2024-07-28 DOI: 10.1177/21925682241270069

Yi Zhang, Jialun Chi, Brock Manley, Eunha Oh, Hanzhi Yang, Jesse Wang, Xudong Li

{"title":"Inflammatory Bowel Disease as a Risk Factor for Complications and Revisions Following Lumbar Discectomy.","authors":"Yi Zhang, Jialun Chi, Brock Manley, Eunha Oh, Hanzhi Yang, Jesse Wang, Xudong Li","doi":"10.1177/21925682241270069","DOIUrl":"https://doi.org/10.1177/21925682241270069","url":null,"abstract":"Study design: Retrospective cohort study.Objectives: Patients with IBD are at an increased risk for postoperative complications following surgery. The goal of this study is to investigate if inflammatory bowel disease (IBD) is a risk factor for complications following lumbar discectomy.Methods: We identified IBD patients who underwent lumbar discectomy for lumbar disc herniation (LDH) and matched to them with controls without IBD in a1:5 ratio. We excluded patients with a history of spinal injury, cancer, infection, trauma, or surgery to remove the digestive tract. We used multivariate logistic regression analyses to compare postoperative outcomes, including 90-day complications, 90-day emergency department visits, and 90-day readmissions. In addition, 2-year re-discectomy rates and a 3-year lumbar fusion rate were compared between the cohorts.Results: After applying the study criteria, we identified 6134 IBD patients with LDH for further analysis. With the exception of dura tears, patients with IBD had significantly higher rates of medical complications, incision-related complications, ED visits, and readmission rates compared to patients without IBD, especially for the 2-year and 3-year rates of disc recurrence and revision surgery.Conclusions: Patients with IBD who underwent lumbar discectomy are at a significantly higher rate of complications. Therefore, spine surgeons and other health care providers should be aware of this higher risk associated with IBD patients and properly treat the patients' IBD before surgery to lower these risks.","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141787807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

We Read With Great Interest the Recent Article by Juan P. Sardi et al Entitled "Opioid Use Prior to Adult Spine Deformity Correction Surgery is Associated with Worse Pre- and Postoperative Back Pain and Prolonged Opioid Demands". 我们饶有兴趣地阅读了 Juan P. Sardi 等人最近发表的题为 "成人脊柱畸形矫正手术前使用阿片类药物与术前、术后背痛加重和阿片类药物需求延长有关 "的文章。

IF 2.6 3区医学

Global Spine Journal Pub Date : 2024-07-27 DOI: 10.1177/21925682241270098

Cangxu Zhang, Shicheng Xie

引用次数: 0

Stand-Alone Lateral Lumbar Interbody Fusion and Lateral Lumbar Interbody Fusion With Supplemental Posterior Instrumentation in the Treatment of Lumbar Degenerative Disease: A Meta-Analysis and Systematic Review. 治疗腰椎退行性疾病的独立外侧腰椎椎间融合术和外侧腰椎椎间融合辅以后路器械：Meta分析和系统回顾。

IF 2.6 3区医学

Global Spine Journal Pub Date : 2024-07-26 DOI: 10.1177/21925682241268333

XiaoCheng Zhou, Qiujun Zhou, Xiaoliang Jin, Jinjie Zhang, Zhoufeng Song

{"title":"Stand-Alone Lateral Lumbar Interbody Fusion and Lateral Lumbar Interbody Fusion With Supplemental Posterior Instrumentation in the Treatment of Lumbar Degenerative Disease: A Meta-Analysis and Systematic Review.","authors":"XiaoCheng Zhou, Qiujun Zhou, Xiaoliang Jin, Jinjie Zhang, Zhoufeng Song","doi":"10.1177/21925682241268333","DOIUrl":"https://doi.org/10.1177/21925682241268333","url":null,"abstract":"Study design: Systematic Review.Objectives: Compare the outcomes of stand-alone lateral lumbar interbody fusion (LLIF) and LLIF with supplemental posterior instrumentation in the treatment of lumbar degenerative disease by a Meta-analysis.Methods: In this meta-analysis, we searched Pubmed, Embase, and Cochrane databases from inception to Aug 2023. In this study, only study reporting stand-alone LLIF(stand-alone group) and LLIF with supplemental posterior instrumentation (posterior instrumentation group) in the treatment of lumbar degenerative disease and we excluded duplicate publications, research without full text, incomplete information or inability to conduct data extraction, animal experiments, reviews, and systematic reviews. STATA 15.1 software was used to analyze the data.Results: Among the 15 included articles, the total number of patients was 1177, with 469 patients (638 fused segments) in the standalone group and 708 patients (1046 fused segments) in the posterior instrumentation group. The posterior instrumentation group was better than stand-alone group with significant differences in fusion rate, cage subsidence rate,the restoration of disc height and segmental lordosis, the improvement of ODI, and reoperation rate. While, comparing with posterior instrumentation group,the stand-alone group had less intraoperative blood loss.Conclusions: Both stand-alone and instrumented LLIF were effective in improving the clinical outcomes of patients with lumbar degenerative disease. However, the stand-alone LLIF was associated with lower fusion rate, inferior maintenance of indirect decompression, and higher reoperation rate due to high-grade cage subsidence. For patients with risk factors of high-grade cage subsidence, the LLIF with posterior instrumentation may be a better choice.","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141758240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letter to the Editor: Effectiveness of a Preoperative Bowel Preparation Protocol for Patients with Adolescent Idiopathic Scoliosis to Decrease Postoperative Gastrointestinal Morbidities and the Hospital Length of Stay. 致编辑的信：青少年特发性脊柱侧凸患者术前肠道准备方案对减少术后胃肠道疾病和住院时间的效果。

IF 2.6 3区医学

Global Spine Journal Pub Date : 2024-07-26 DOI: 10.1177/21925682241270088

Zhe Hu, Zhikang Tian, Hongmei Liu, Yueqin Chen

引用次数: 0