成人畸形手术中如何降低机械故障的风险:GAP评分与Roussouly型修复的比较。

IF 2.6 3区 医学 Q2 CLINICAL NEUROLOGY
Domenico Compagnone, Riccardo Cecchinato, Andrea Pezzi, Francesco Langella, Marco Damilano, Daniele Vanni, Andrea Redaelli, Claudio Lamartina, Pedro Berjano
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引用次数: 0

摘要

研究设计:回顾性队列研究。目的评估与机械并发症相关的长期对齐描述符。方法本研究纳入18岁以上的成人脊柱畸形病例,至少有4个固定节段,随访5年。排除:既往脊柱融合术、神经肌肉/风湿病、活动性感染、肿瘤或不完整的影像学检查。收集的数据:人口统计学、手术、术前和术后脊柱参数以及术后并发症。使用机器学习和逻辑回归评估GAP评分、原始Roussouly型恢复、Schwab标准和齿状突到髋轴的角度。用Kaplan-Meier曲线评估并发症。结果符合纳入和排除标准的212例患者被纳入研究。观察到机械性并发症的翻修手术率为40.6%(212例患者中有86例)。术后GAP评分越高,结膜功能衰竭翻修的风险越高(AUC = 0.72 [IC 95%] 0.62-0.80)。无法恢复原来的Roussouly脊柱形状在统计学上与较高的机械故障率相关。机器学习方法和随后的逻辑回归发现,GAP评分和原始Roussouly型恢复是机械故障最重要的预测因子,GAP评分前凸分布指数和相对骨盆版本是预测机械故障风险的最重要因素。结论在我们的研究中,适当的术后GAP评分和原始Roussouly类型的恢复可显著减少机械并发症的发生率。我们观察到,在并发症中,连接功能衰竭往往发生得较早,而种植体功能衰竭发生得较晚。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
How to Reduce the Risk of Mechanical Failures in Adult Deformity Surgery: Comparing GAP Score and Roussouly Type Restoration.

Study DesignRetrospective Cohort Study.ObjectivesTo assess long-term alignment descriptors correlating with mechanical complications.MethodsThe study included adult spinal deformity cases older than 18, with a minimum of four instrumented levels and a 5-year follow-up. Exclusions: previous spinal fusion, neuromuscular/rheumatic diseases, active infections, tumors, or incomplete radiographic exams. Collected data: demographic, surgical, pre- and post-operative spinopelvic parameters, and post-operative complications. The GAP score, original Roussouly type restoration, Schwab's criteria, and Odontoid to hip axis angle were evaluated using machine learning and logistic regression. Complications were evaluated with a Kaplan-Meier curve.ResultsTwo hundred and twelve patients fulfilled the inclusion and exclusion criteria and were enrolled in the study. The observed rate of revision surgery for mechanical complications was 40.6% (86 out of 212 patients). Higher post-operative GAP scores were associated with increased risks of revision for junctional failure (AUC = 0.72 [IC 95%] 0.62-0.80). The inability to restore the original Roussouly spinal shape was statistically associated with higher mechanical failure rates. A machine-learning approach and subsequent logistic regression found that the GAP score and original Roussouly type restoration are the most important predictors for mechanical failure, and GAP score lordosis distribution index and relative pelvic version are the most important factors to predict the risk of mechanical failure.ConclusionsIn our series, a proper post-operative GAP Score and the restoration of the original Roussouly type significantly minimize mechanical complication rates. We observed that junctional failure tends to occur earlier among complications, while implant failure occurs later in the follow-up.

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来源期刊
Global Spine Journal
Global Spine Journal Medicine-Surgery
CiteScore
6.20
自引率
8.30%
发文量
278
审稿时长
8 weeks
期刊介绍: Global Spine Journal (GSJ) is the official scientific publication of AOSpine. A peer-reviewed, open access journal, devoted to the study and treatment of spinal disorders, including diagnosis, operative and non-operative treatment options, surgical techniques, and emerging research and clinical developments.GSJ is indexed in PubMedCentral, SCOPUS, and Emerging Sources Citation Index (ESCI).
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