{"title":"\"Emergency Department Predictors of Mechanical Ventilation in Pediatric Spine Fracture Patients in the US\".","authors":"Ercan Yılmaz, Zeynep Yamancan Yılmaz","doi":"10.1177/21925682261491358","DOIUrl":"10.1177/21925682261491358","url":null,"abstract":"","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682261491358"},"PeriodicalIF":3.1,"publicationDate":"2026-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13593941/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149012248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samer G Salman, Rohan A Phadke, Margaret A Baldwin
{"title":"Response to Comment on \"Emergency Department Predictors of Mechanical Ventilation in Pediatric Spine Fracture Patients in the US\".","authors":"Samer G Salman, Rohan A Phadke, Margaret A Baldwin","doi":"10.1177/21925682261491361","DOIUrl":"10.1177/21925682261491361","url":null,"abstract":"","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682261491361"},"PeriodicalIF":3.1,"publicationDate":"2026-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13593954/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149012235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on: \"Impact of Concomitant Grade I Degenerative Spondylolisthesis on Clinical and Radiographic Outcomes Following Biportal Endoscopic Versus Microscopic Laminectomy for Lumbar Spinal Stenosis: A Post Hoc Analysis of a Multicenter Randomized Clinical Trial\".","authors":"Sharath Raj, Vijay Goni","doi":"10.1177/21925682261491295","DOIUrl":"10.1177/21925682261491295","url":null,"abstract":"","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682261491295"},"PeriodicalIF":3.1,"publicationDate":"2026-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13589780/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149008438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of Concomitant Grade I Degenerative Spondylolisthesis on Clinical and Radiographic Outcomes.","authors":"Hinpetch Daungsupawong, Viroj Wiwanitkit","doi":"10.1177/21925682261492306","DOIUrl":"10.1177/21925682261492306","url":null,"abstract":"","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682261492306"},"PeriodicalIF":3.1,"publicationDate":"2026-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13589781/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149008375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comments on \"Impact of Immunosuppression Type on 30-Day Postoperative Outcomes Following Anterior Cervical Discectomy and Fusion: A Retrospective National Cohort Study of 66,162 Patients\".","authors":"Fatih Kaplan, Bilge Kurnaz Kaplan","doi":"10.1177/21925682261492305","DOIUrl":"10.1177/21925682261492305","url":null,"abstract":"","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682261492305"},"PeriodicalIF":3.1,"publicationDate":"2026-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13589779/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149008450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrei Fernandes Joaquim, Shanmuganathan Rajasekaran
{"title":"Strategies for High-Quality Spine Surgery in Resource-Limited Settings: The Five-P Framework for Equitable Surgical Delivery.","authors":"Andrei Fernandes Joaquim, Shanmuganathan Rajasekaran","doi":"10.1177/21925682261491746","DOIUrl":"10.1177/21925682261491746","url":null,"abstract":"<p><p>Study DesignNarrative review with a Conceptual Framework.ObjectivesLow- and middle-income countries (LMICs), home to approximately 80-85% of the global population, face a disproportionate burden of spinal disorders and limited access to timely, safe, and affordable surgical care. This review proposes a practical framework for delivering high-value spine care in LMICs by integrating evidence on health systems, value-based healthcare, and spine surgery into five strategic domains: Policy & Governance, Patient Selection, Perioperative Efficiency, Products & Technology, and Protection (the Five-P Framework).MethodsA narrative review with a structured literature search was conducted using PubMed and gray literature. Studies on spinal care delivery, health systems, cost-effectiveness, and surgical strategies in LMICs or comparable settings were qualitatively synthesized into thematic domains.ResultsFive domains were identified: (1) <b>P</b>olicy & Governance, including centralization of care, regulation of financial incentives, anti-corruption measures, and complication reduction; (2) <b>P</b>atient Selection, emphasizing evidence-based indications; (3) <b>P</b>erioperative Efficiency, including enhanced recovery pathways, ambulatory surgery, and standardized protocols; (4) <b>P</b>roducts & Technology, focusing on resource optimization and context-appropriate technologies, including locally manufactured implants; and (5) <b>P</b>rotection, promoting balanced medicolegal frameworks. Together, these domains aim to maximize value, improve access, and reduce unnecessary procedures and inefficient resource utilization.ConclusionThe Five-P Framework is a theoretical model that provides a system-level strategy to improve access to high-value spine care in LMICs through appropriate patient selection, efficient perioperative care, and optimal use of limited resources. Future studies to validate this proposal are necessary.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682261491746"},"PeriodicalIF":3.1,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13588966/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148989666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tobechukwu C Ndika, Joshua Woo, Brandon T Lee, Eli Johnson, Ezinne Oguguo, Nicole Rivera, Emanuel J Ray, Adedotun Bello, Jessica D'wambe Tiako, Liban Mohamed, Sheng-Fu Larry Lo, Daniel M Sciubba, Rafael De la Garza Ramos, John E O'Toole, Pakawat Chongsathidkiet, Tara Dalton, Kerri-Anne Crowell, Megan Von Isenburg, Trey Mullikin, Melissa Erickson, C Rory Goodwin
{"title":"Current Trends in Therapeutic Outcomes Among Patients With Metastatic Renal Cell Carcinoma of the Spine: A Systematic Review and Meta-Analysis.","authors":"Tobechukwu C Ndika, Joshua Woo, Brandon T Lee, Eli Johnson, Ezinne Oguguo, Nicole Rivera, Emanuel J Ray, Adedotun Bello, Jessica D'wambe Tiako, Liban Mohamed, Sheng-Fu Larry Lo, Daniel M Sciubba, Rafael De la Garza Ramos, John E O'Toole, Pakawat Chongsathidkiet, Tara Dalton, Kerri-Anne Crowell, Megan Von Isenburg, Trey Mullikin, Melissa Erickson, C Rory Goodwin","doi":"10.1177/21925682261488401","DOIUrl":"10.1177/21925682261488401","url":null,"abstract":"<p><p>Study DesignSystematic Review.ObjectivesThe objective of this study was to answer two questions: (1) Did the overall survival (OS) of patients with spinal metastatic renal cell carcinoma (mRCC) improve in publications from 2017 and afterwards compared to 2016 and before? (2) Did the rate of improvement in pain or neurological deficits increase in publications from 2017 and afterwards within this population?MethodsA comprehensive search was conducted to include studies that evaluated either survival or clinical outcomes in the spinal mRCC population from 1986 to 2024.Results63 studies encompassing 1,968 patients were included. The mean age was 59.1 years and 70.85% of patients were male. Pain and neurological deficits were the most common presenting symptoms, seen in 37.5% and 36.0% of patients, respectively. Compared with earlier studies, those published during or after 2017 reported improved median OS across spine surgery (27 vs. 12.3 months), radiotherapy (41.3 vs. 10.8 months), and systemic therapy (29.01 vs. 11.45 months) groups. Meta-analysis of 1-year overall survival for patients undergoing spine surgery showed significant improvement from 2017 afterwards (p<0.05). The neurological improvement rate was significantly higher from 2017 afterwards although pain relief did not differ between publication eras.ConclusionsStudies published from 2017 onward report better survival among spinal mRCC patients than earlier studies. Since the analysis is keyed to publication era rather than the therapy each patient received, the contribution of individual modalities cannot be separated, and the improvement likely reflects advances in surgery, radiotherapy, systemic therapy, and patient selection.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682261488401"},"PeriodicalIF":3.1,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13586073/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148989661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel Rusu, Aidan Lindgren, Natalie M Kistler, Niels Mohty, Thomas W Mason, Marc A Abdou, Jeffrey C Wang, Raymond J Hah, Ram K Alluri
{"title":"Resurgence in BMP Use in Spine Surgery: An Analysis From 2010 to 2022.","authors":"Daniel Rusu, Aidan Lindgren, Natalie M Kistler, Niels Mohty, Thomas W Mason, Marc A Abdou, Jeffrey C Wang, Raymond J Hah, Ram K Alluri","doi":"10.1177/21925682261491658","DOIUrl":"10.1177/21925682261491658","url":null,"abstract":"<p><p>Study DesignRetrospective Cohort.ObjectivesTo evaluate trends in bone morphogenetic protein (BMP) utilization across spinal fusion procedures.MethodsPatients undergoing anterior cervical discectomy and fusion (ACDF), posterior cervical decompression and fusion (PCDF), anterior lumbar interbody fusion (ALIF), or posterior/transforaminal lumbar interbody fusion (PLIF/TLIF) between January 1, 2010 and April 30, 2023 were identified in the PearlDiver Mariner Database. BMP utilization was identified using ICD-9/10 codes and assessed annually as a percentage of total cases, with 2023 omitted due to incomplete data. Subgroup analysis stratified annual trends by number of levels fused. Temporal trends in patient demographics were compared between early (2010-2016) and late (2017-2023) cohorts using Welch's t-test and Pearson chi-squared test of independence.ResultsA total of 596,453 ACDF, 104,287 PCDF, 159,575 ALIF, and 622,252 PLIF/TLIF cases were identified, respectively. Across all procedures, BMP utilization declined to a nadir in 2017, followed by marked increase. From 2017 to 2022, BMP utilization increased by 667% in ACDF, 1138% in PCDF, 441% in ALIF, and 900% in PLIF/TLIF. BMP use was higher in multi-level PCDF and PLIF/TLIF compared to single-level, whereas ALIF demonstrated slightly higher utilization in single-level cases. In the later cohort, patients receiving BMP were older, had greater comorbidity burden, and longer hospital stays across all procedures (p<0.001).ConclusionsBMP utilization in spine surgery declined steadily until 2017, followed by marked increase through 2022, particularly in multi-level posterior cervical and lumbar fusions and among high-risk patients. This likely reflects evolving evidence supporting optimized dosing and improved safety profiles.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682261491658"},"PeriodicalIF":3.1,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13586078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148989676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elyette Lugo, Krystell E Ceballos-Alvarez, Sydney Thai, K Daniel Riew, Sang Hun Lee, S Tim Yoon, Christopher Martin, Samuel Cho, Amit Jain
{"title":"Global Variation in Fusion Assessment Practices Following Anterior Cervical Discectomy and Fusion.","authors":"Elyette Lugo, Krystell E Ceballos-Alvarez, Sydney Thai, K Daniel Riew, Sang Hun Lee, S Tim Yoon, Christopher Martin, Samuel Cho, Amit Jain","doi":"10.1177/21925682261488404","DOIUrl":"10.1177/21925682261488404","url":null,"abstract":"<p><p>Study DesignCross-sectional survey.ObjectivesTo characterize global variation in imaging modalities, fusion criteria, and decision-making practices for assessing fusion following anterior cervical discectomy and fusion (ACDF).MethodsA modified 30-item survey using Delphi-informed methodology was distributed to global cervical spine experts selected by research impact. Response rate was 40%. Items addressed surgeon demographics, preferred fixation and interbody techniques, bracing protocols, imaging strategies, and perceived strength of evidence for fusion assessment criteria. Responses were analyzed descriptively.ResultsSubstantial variation was observed in imaging preferences and fusion criteria. Most surgeons preferred plate fixation for both 1-2 level ACDF (mean 71%) and 3-4 level ACDF (mean 92%). Metallic cages were the most frequently used interbody devices, with mean preferences of 40% for 1-2 levels and 42% for 3-4 levels. Fusion status and patient satisfaction were the primary determinants of follow-up duration. Flexion-extension radiographs and CT were the most frequently used modalities. The strongest endorsed criteria for fusion were <1 mm interspinous motion, <5° angular motion, and graft bridging bone ≥2 mm on CT, though up to 20% of surgeons still rated these measures as moderate or poor evidence. While 77.8% endorsed the need for standardized criteria, only half were aware of existing guidelines.ConclusionsAlthough commonly used measures such as <1mm interspinous motion, <5° angular motion, and CT-based extra-graft bridging bone are supported by prior studies, the absence of standardized diagnostic criteria limits confidence in their validity and highlights the urgent need for a universally accepted, evidence-based standard for fusion after ACDF.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682261488404"},"PeriodicalIF":3.1,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13582644/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148976700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}