D Compagnone, L La Verde, A Redaelli, D Solano, F Langella, M Damilano, D Vanni, C Lamartina, P Berjano, R Cecchinato
{"title":"Adherence to the Lamartina-Berjano Classification and Suggested Surgical Treatment Decreases the Rate of Postoperative Mechanical Failures in Adult Deformity Patients. A Retrospective Observational Study With a Minimum 10 Years Follow-Up.","authors":"D Compagnone, L La Verde, A Redaelli, D Solano, F Langella, M Damilano, D Vanni, C Lamartina, P Berjano, R Cecchinato","doi":"10.1177/21925682251332555","DOIUrl":"10.1177/21925682251332555","url":null,"abstract":"<p><p>Study DesignRetrospective cohort analysis.ObjectivesTo evaluate the effectiveness of the Lamartina-Berjano (L-B) classification in reducing mechanical complications in patients with adult spinal deformities, with a minimum follow-up of 10 years.MethodsThe study included cases of adult deformity with at least 10 years of follow-up. The rate of clinically-relevant mechanical complications, defined as any implant-related issue requiring revision surgery, was estimated. The independent variable was adherence to the treatment guidelines of the L-B classification. The analysis was limited to patients with thoracolumbar deformities, and the population was stratified according to postoperative alignment using GAP scores.ResultsA total of 121 patients met the inclusion and exclusion criteria. In this cohort, the revision surgery rate for clinically-relevant mechanical complications was 49.6% (60 out of 121 patients). Of these, 90 patients (74%) had surgery following the L-B classification guidelines. A lower risk of complications was observed in aligned patients whose surgeries adhered to the L-B classification. Additionally, the survival curve showed significant differences between patients who followed L-B guidelines and those who did not.ConclusionOur retrospective analysis shows that following the L-B classification guidelines leads to a reduction in mechanical complications in patients with thoracolumbar deformities, particularly in a long-term follow-up scenario.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251332555"},"PeriodicalIF":2.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11955972/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143729577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Leevi A Toivonen, Heikki Mäntymäki, Lorin M Benneker, Hannu Kautiainen, Marko H Neva
{"title":"Letter Re: \"Effect of Baseline Adjacent Segment Degeneration on Clinical Outcomes After Lumbar Fusion\".","authors":"Leevi A Toivonen, Heikki Mäntymäki, Lorin M Benneker, Hannu Kautiainen, Marko H Neva","doi":"10.1177/21925682251330264","DOIUrl":"https://doi.org/10.1177/21925682251330264","url":null,"abstract":"","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251330264"},"PeriodicalIF":2.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11954376/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marcin Czyz, Emerens G Wensink, Brian Coimbra, Michael Galgano, Shreyaskumar Patel, Kristin Redmond, Joost Rutges, Jiong Hao Jonathan Tan, Ori Barzilai, Nicolas Dea, Alessandro Gasbarrini, Ilya Laufer, Aron Lazary, Cordula Netzer, Jeremy J Reynolds, Laurence D Rhines, Arjun Sahgal, Charles G Fisher, Jorrit-Jan Verlaan
{"title":"AO Spine Clinical Practice Recommendations: Current Systemic Oncological Treatments with the Largest Impact on Patients with Metastatic Spinal Disease.","authors":"Marcin Czyz, Emerens G Wensink, Brian Coimbra, Michael Galgano, Shreyaskumar Patel, Kristin Redmond, Joost Rutges, Jiong Hao Jonathan Tan, Ori Barzilai, Nicolas Dea, Alessandro Gasbarrini, Ilya Laufer, Aron Lazary, Cordula Netzer, Jeremy J Reynolds, Laurence D Rhines, Arjun Sahgal, Charles G Fisher, Jorrit-Jan Verlaan","doi":"10.1177/21925682251324138","DOIUrl":"10.1177/21925682251324138","url":null,"abstract":"<p><p>Study DesignLiterature review with clinical recommendation.ObjectiveTo provide the readers with a concise curation of the latest literature in recent advances in systemic oncological therapies and their implications for decision-making in patients with metastatic spinal disease. This review aims to enhance spine specialist's understanding of modern oncological treatments to facilitate optimal timing and planning of local interventions.MethodsThe latest literature in the topic of advances in oncology was reviewed by a multidisciplinary group of experts in metastatic spinal disease and clinical recommendations were formulated. The recommendations were dichotomously graded into strong and conditional (weak) based on the integration of scientific methodology and content expert opinion. This opinion considered experience and practical issues such as risks, burdens, costs, patient values, and circumstances.ResultsFour high-impact studies were reviewed, demonstrating significant advancements in systemic treatments for metastatic cancers commonly affecting the spine. These studies showed improved survival outcomes and efficacy across breast cancer, colorectal cancer, prostate cancer, and renal cell carcinoma. The findings have important implications for surgical/radiotherapy planning, including considerations for timing of interventions, wound healing, and the potential for extended survival affecting construct durability requirements.ConclusionsRecent advances in systemic oncological treatments have important implications for managing metastatic spinal disease. Understanding these developments is crucial for spine specialists to optimize decision-making through a multidisciplinary approach, particularly regarding timing of local interventions, strategy of the surgical approach and reconstruction.[Formula: see text].</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251324138"},"PeriodicalIF":2.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11955994/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143735762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paul G Mastrokostas, Mohamed Said, Christian Cassar, Leonidas E Mastrokostas, Aaron B Lavi, Arya Varthi, Jad Bou Monsef, Afshin E Razi, Mitchell K Ng
{"title":"Obstructive Sleep Apnea is Associated With Increased Rates of Acute Respiratory Failure, Length of Stay, and Hospital Costs in Patients Undergoing Elective Single-Level Anterior Cervical Discectomy and Fusion.","authors":"Paul G Mastrokostas, Mohamed Said, Christian Cassar, Leonidas E Mastrokostas, Aaron B Lavi, Arya Varthi, Jad Bou Monsef, Afshin E Razi, Mitchell K Ng","doi":"10.1177/21925682251333324","DOIUrl":"10.1177/21925682251333324","url":null,"abstract":"<p><p>Study designRetrospective cohort study.ObjectivesTo examine differences in postoperative complications, recovery course, and costs between patients with and without obstructive sleep apnea (OSA) undergoing single-level anterior cervical discectomy and fusion (ACDF).MethodsThe National Inpatient Sample (NIS) database was queried to identify patients undergoing single-level ACDF between 2016 and 2022. After exclusions, patients were divided into OSA and control groups. Propensity score matching (1:2) controlled for age, sex, obesity, and year of surgery to balance characteristics. Postoperative outcomes, including complications, length of stay (LOS), hospital costs, and discharge disposition, were compared using chi-square tests for categorical variables and t-tests for continuous variables. A Bonferroni correction was applied, with significance set at <i>P</i> < 0.002.ResultsA total of 36,000 matched cases were analyzed (12,000 OSA and 24,000 controls). OSA patients had significantly higher rates of acute respiratory failure (4.7% vs 1.9%; <i>P</i> < 0.001) and mechanical ventilation (1.5% vs 0.6%; <i>P</i> < 0.001). The OSA cohort also had a longer LOS (2.3 vs 1.9 days; <i>P</i> < 0.001), higher hospital costs ($23,300 vs $21,100; <i>P</i> < 0.001), and greater non-routine discharge rates (20.4% vs 16.8%; <i>P</i> < 0.001).ConclusionsOSA is associated with increased respiratory complications, prolonged LOS, and higher costs in single-level ACDF. These findings underscore the importance of preoperative screening and tailored perioperative management to improve outcomes in this high-risk population.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251333324"},"PeriodicalIF":2.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11954374/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143735764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response to Letter to the Editor Regarding the Article Entitled \"Trabecular Bone Remodeling After Posterior Lumbar Interbody Fusion: Comparison of the Osseointegration in Three-Dimensional Porous Titanium Cages and Polyether-Ether-Ketone Cages\" by Segi et al.","authors":"Naoki Segi, Hiroaki Nakashima, Sadayuki Ito, Jun Ouchida, Ippei Yamauchi, Tomohiro Matsumoto, Shunsuke Kanbara, Keigo Ito, Shiro Imagama","doi":"10.1177/21925682251332558","DOIUrl":"10.1177/21925682251332558","url":null,"abstract":"","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251332558"},"PeriodicalIF":2.6,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11951122/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143729374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Minimally Invasive Transpedicular Posterolateral Approach (MITPA) Corpectomy in the Treatment of Traumatic or Metastatic Vertebral Collapse With Kyphosis.","authors":"Wiktor Urbanski, Rafal Zaluski","doi":"10.1177/21925682251325167","DOIUrl":"10.1177/21925682251325167","url":null,"abstract":"<p><p>Study DesignRetrospective observational cohort study.Vertebral body collapse with subsequent kyphosis, compression of neural structures usually requires surgical treatment; spinal fixation, corpectomy, decompression and realignment of the spine.The objective was to present results of corpectomies using a unilateral minimally invasive posterolateral transpedicular approach (MITPA) in patients with metastatic or posttraumatic kyphosis.Material and MethodsThe study included 28 patients: 23 with osteolytic vertebral body metastases, 5 posttraumatic kyphosis. All patients were operated by 2 surgeons, all had percutaneous pedicle fixation and unilateral single-level corpectomy using MITPA, followed by insertion of an expandable cage. Perioperative parameters were noted and radiological analysis based on CT performed before, after surgery and on the last follow up in 12 months.ResultsThe mean age of patients was 62 years, average length of surgery 263 min, with mean EBL 648 mL and average length of hospital stay 9.3 days. The local kyphosis, measured on end-plates of adjacent vertebrae, was corrected by 14.3° (from 13.1° [±9] to -1.2° [±8], <i>P</i> < .05). Complications occurred in 11 patients (39%), most of them minor, only 2 complications were major (7%): 1 deteriorated neurological deficit and 1 deep vein thrombosis. In 8 cases of preoperative paresis, 7 showed postoperative neurological improvement. In 12 months follow up, no serious mechanical complications were observed, beside minor cage subsidence in 5 cases and adjacent vertebral fracture. The anterior fusion was noted in all cases followed.ConclusionsMITPA corpectomy allows for significant correction of kyphosis, both in metastatic and posttraumatic vertebral body collapse with relatively low rate of major complications.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251325167"},"PeriodicalIF":2.6,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11955983/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143729204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vadim A Byvaltsev, Andrei A Kalinin, Yurii Ya Pestryakov, Marat A Aliyev, Ravshan M Yuldashev, Yermek K Dyussembekov, K Daniel Riew
{"title":"Effect of Different Minimally Invasive Posterior Stabilization Techniques After Direct Lateral Interbody Fusion With Long-Term Clinical and Radiological Outcomes in Railway Workers: A Retrospective Single-Center Study.","authors":"Vadim A Byvaltsev, Andrei A Kalinin, Yurii Ya Pestryakov, Marat A Aliyev, Ravshan M Yuldashev, Yermek K Dyussembekov, K Daniel Riew","doi":"10.1177/21925682251331462","DOIUrl":"10.1177/21925682251331462","url":null,"abstract":"<p><p>Study DesignRetrospective study.ObjectiveTo investigate the clinical and radiological outcomes of patients with lumbar degenerative disc disease (DDD) treated with one-level Direct lateral interbody fusion (DLIF) in combination with minimally invasive percutaneous pedicle screw fixation (PPSF) and percutaneous facet joint fixation (PFJF).MethodsThis retrospective single-center study included 98 patients (67 men, 31 women) aged 28 to 59 years with one level lumbar DDD with foraminal and central stenosis, were divided into groups after DLIF: PPSF (n = 50) and PFJF (n = 48). Intraoperative parameters, perioperative clinical data and radiological assessment with X-ray, MRI and CT were used before operation and mean 45-month follow-up. Workload intensity criteria were used to analyze return to work rate.ResultsThe DLIF-PFJF group had significantly shorter surgery time (<i>P</i> = .04), duration of anesthesia (<i>P</i> = .02), X-ray time (<i>P</i> = .02), less back pain (<i>P</i> = .03), better functional status according to ODI (<i>P</i> = .04) and SF-36 PCS (<i>P</i> = .04), less atrophic changes in the multifidus muscle compared with DLIF-PPSF. There were no statistically significant differences in the volume of blood loss, duration of inpatient treatment, VAS leg pain, SF-36 MCS, Macnab results, mean disc height, intervertebral foramen height, sagittal disc angle, global lumbar lordosis, fusion rate, and the number of complications. In heavy/very heavy workload patients, the DLIF-PFJF had a statistically significantly higher rate of return to work compared to the DLIF-PPSF group.ConclusionsDLIF-PFJF appears to be superior to DLIF-PPSF, minimizing invasiveness, which significantly reduces the damage to the paraspinal muscles and also has significant long-term clinical advantages and return to work rates. Both minimally invasive techniques have comparable radiographic parameters, including the height of the intervertebral foramen and disc, fusion rates, global and segmental sagittal correction after surgery.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251331462"},"PeriodicalIF":2.6,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11955978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143728486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to Editor Regarding \"Trabecular Bone Remodelling After Posterior Lumbar Interbody Fusion: Comparison of the Osseointegration in Three-Dimensional Porous Titanium Cages and Polyether-Ether-Ketone Cages\" by Segi et al.","authors":"Aditya Gupta, Vishal Kumar, Sarvdeep Singh Dhatt, Surya Teja Dunga","doi":"10.1177/21925682251332207","DOIUrl":"10.1177/21925682251332207","url":null,"abstract":"","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251332207"},"PeriodicalIF":2.6,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11955973/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143728739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of Stand-Alone Anchored Spacer and Plate-Cage Construct for Surgical Treatment of Multilevel Cervical Degenerative Spondylopathy: A Meta-Analysis.","authors":"Chao-Jui Chang, Yuan-Fu Liu, Yu-Meng Hsiao, Wei-Lun Chang, Yi-Hung Huang, Keng-Chang Liu, Che-Chia Hsu, Ming-Long Yeh, Cheng-Li Lin","doi":"10.1177/21925682251327599","DOIUrl":"10.1177/21925682251327599","url":null,"abstract":"<p><p>Study DesignMeta-analysis study.ObjectivesWe aimed to compare clinical outcomes, radiologic parameters, and complications between the stand-alone anchored spacer and the plate-cage construct as treatment options for patients with multilevel cervical degenerative spondylopathy involving 3 or 4 levels.MethodsIn this meta-analysis, we adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The search for relevant studies covered the Embase, PubMed, and Cochrane Central Register of Controlled Trials databases, encompassing data from the inception of each database up to July 1, 2024.ResultsThe analysis included 12 studies, involving a total of 817 patients. Patients in the stand-alone anchored spacer group exhibited decreased intraoperative blood loss and shorter surgical durations. Clinical outcomes, including visual analog scale (VAS) scores, Japanese Orthopaedic Association (JOA) scores, Neck Disability Index (NDI) scores, and Odom's criteria for clinical outcomes, demonstrated no significant differences between the two groups. Radiographic outcomes revealed no statistically significant difference in fusion rates between stand-alone cages and plate-cage constructs. However, the plate-cage group exhibited more favorable maintenance of segmental angle and cervical alignment (C2-C7 angle).ConclusionsBoth stand-alone anchored spacer and plate-cage constructs are viable treatment options for patients with cervical degenerative spondylopathy involving more than two levels. Stand-alone cages have the benefit of reducing intraoperative blood loss and shortening surgical durations, but they are associated with a higher risk of cage subsidence. Plate-cage constructs offer better maintenance of segmental angle and cervical alignment; however, they carry a higher risk of dysphagia.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251327599"},"PeriodicalIF":2.6,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11948229/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}