Global Spine Journal最新文献

{"title":"Letter to the Editor Regarding \"Vancomycin Antibiotic Prophylaxis Compared to Cefazolin Increases Risk of Surgical Site Infection Following Spine Surgery\".","authors":"Misael Salazar-Alejo, Hector R Martinez, Jose A Figueroa-Sanchez, Ana Ballesteros-Suarez, Mario Benvenutti-Regato","doi":"10.1177/21925682251352851","DOIUrl":"10.1177/21925682251352851","url":null,"abstract":"","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251352851"},"PeriodicalIF":2.6,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12181181/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144336455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global, Regional, and National Burden of Neck Pain in Young Population, 1990-2021: An Age-Period-Cohort Analysis and Projections to 2050 Based on the Global Burden of Disease Study 2021.","authors":"Xiaohan Jing, Yuan Wang, Yuchen Zhang, Fan Li, Di Tian, Feilong Zhang, Yuting Chen, Ye Wu","doi":"10.1177/21925682251352847","DOIUrl":"10.1177/21925682251352847","url":null,"abstract":"<p><p>Study DesignEco-epidemiological study.ObjectiveAnalysis the spatial-temporal trends in neck pain burden among young people at global, regional, and national levels.MethodsData on neck pain among youth from 1990 to 2021 was sourced from the Global Burden Disease (GBD) 2021 database. This research delineated the evolving trends in neck pain burden by comparing various regions and timeframes, employing the age-period-cohort (APC) model to assess the factors effects on neck pain burden. The Autoregressive Integrated Moving Average (ARIMA) model was utilized to forecast the global burden of neck pain among youth by 2050s.ResultsAlthough the global burden of neck pain shows a steady development trend, there is strong heterogeneity among regions. The burden was more severe in the females and high-middle Socio-Demographic Index (SDI) region. By APC model, the burden was found to increase with age, and the period effect showed an initial upward trend followed by a decline and rise final, although the relative risk remained above 1. The cohort effect indicated that the relative risks for global, higher SDI, initially decreased before rising, while the relative risks for low-middle SDI and low SDI regions have continued to increase over the years. Predictive modeling showed by 2050, the number of youth suffering from neck pain will continue.ConclusionsNeck pain remains an important health problem and poses a global public health challenge in the future, requiring prevention and control targeting key populations and regions.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251352847"},"PeriodicalIF":2.6,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12181195/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144336454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of Cervical Spondylosis With Dysphagia Caused by Anterior Osteophytes: A Retrospective Case Series Study.","authors":"Rui Chen, Ben Wang, Yanbin Zhao, Yinze Diao, Xin Chen, Shengfa Pan, Fengshan Zhang, Yu Sun, Feifei Zhou, Zhongjun Liu","doi":"10.1177/21925682251351619","DOIUrl":"10.1177/21925682251351619","url":null,"abstract":"<p><p>ObjectiveThis study aimed to evaluate the clinical characteristics, surgical outcomes, and prognostic factors of cervical spondylosis in patients with dysphagia caused by anterior osteophytes.MethodsThis retrospective study included 28 patients who underwent anterior cervical surgery for dysphagia associated with anterior osteophytes between January 2006 and January 2023. Clinical data, including preoperative evaluations, surgical reports, and follow-up visits, were collected from electronic medical records. Cervical spine degeneration was confirmed by radiographic examinations. Dysphagia severity was assessed by the Functional Outcome Swallowing Scale (FOSS) preoperatively and at follow-up. Statistical analyses were conducted to compare pre- and postoperative outcomes.ResultsThe average age was 62.4 years, and 78.6% were men. All patients experienced dysphagia, with severity ranging from grades 1-4. After surgery, 89.3% of the patients showed symptomatic improvement, defined as a reduction of at least one grade on the FOSS. Complications were infrequent, primarily consisting of axial pain (10.7%), along with less common occurrences of esophageal fistula, stenosis, nutritional insufficiency, and myelitis (each at 3.6%). Both the modified Japanese Orthopaedic Association (mJOA) score and Neck Disability Index (NDI) showed significant postoperative improvement. The most frequently involved segments were C5/6 and C4/5.ConclusionAnterior cervical osteophyte resection, with or without fusion, appears effective in relieving dysphagia symptoms and improving neurological function in well-selected patients. Further prospective studies are needed to validate these findings and refine surgical strategies.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251351619"},"PeriodicalIF":2.6,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12174584/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Craniocervical Junction and Upper Cervical Spine Fractures: Historical Systems and Advancements with the AO Spine Classification.","authors":"Barry Ting Sheen Kweh, Alexander R Vaccaro, Gregory Schroeder, Jose A Canseco, Maximilian Reinhold, Mohamed Aly, Sebastian Bigdon, Mohamed El-Skarkawi, Richard J Bransford, Andrei Fernandes Joaquim, Harvinder Singh Chhabra, Emiliano Vialle, Rishi M Kanna, Charlotte Dandurand, Cumhur Öner, Jin Wee Tee","doi":"10.1177/21925682251351943","DOIUrl":"10.1177/21925682251351943","url":null,"abstract":"<p><p>Study DesignSystematic Review.ObjectivesTo describe existing craniocervical junction and upper cervical spine classification systems and their integration into a unified rational hierarchical system of the AO Spine Upper Cervical Injury Classification System (UCIC).MethodsA systematic review of MEDLINE, EMBASE and Cochrane Databases was performed in keeping with the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines.Results859 articles were identified which yielded 10 established classification systems for injuries of the occipital condyles, craniocervical junction as well as atlas and axis. All systems were either non-hierarchical, conferred minimal clinical significance or failed to consider neurological status of patients. For example, the Traynelis classification simply relies upon describing the direction of displacement which has dubious clinical significance. Similarly, the Jefferson description of atlas fractures simply grades injuries by fracture line pattern. The AO Spine UCIC system synthesizes each published historical scheme into a rational graded method by which clinicians can assess the severity of injuries to this region. The three grades of injury range from type A being generally stable bony injuries, type B constituting potentially unstable (osseoligamentous) injuries and type C representing grossly unstable translational injuries.ConclusionThe AO Spine UCIC System is a validated methodology of integrating historical landmark grading systems and evolving this into a structured means of grading severity of injuries to guide timely clinical management. The implementation of this universal system will enable clinicians to consistently assess craniocervical junction injuries and implement appropriate management strategies. Future studies will examine outcomes after operative or non-operative management with progression to a standardized quantified algorithm.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251351943"},"PeriodicalIF":2.6,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12176786/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AO Spine Clinical Practice Recommendations: Reducing the Surgical Footprint of Surgery for Spinal Metastases.","authors":"Alvaro Silva González, Hanbo Chen, Alexander C Disch, Jeremy Kam, John E O'Toole, Nicolas Dea, Alessandro Gasbarrini, Ilya Laufer, Cordula Netzer, Jeremy Reynolds, Laurence D Rhines, Arjun Sahgal, Jorrit-Jan Verlaan, Charles G Fisher, Ori Barzilai","doi":"10.1177/21925682251352442","DOIUrl":"10.1177/21925682251352442","url":null,"abstract":"<p><p>Study DesignLiterature review with clinical recommendations.ObjectiveSpinal metastases represent a late complication of cancer and a major factor in decreased quality of life. The role of surgery for specific indications for spinal metastases is well established. Given the significant morbidity associated with spine surgery in this frail population, efforts are ongoing to decrease the surgical footprint. The objective of this study is to provide the readers with a concise curation of the latest spine literature on reducing the surgical footprint for spine metastases and clinical recommendations for how the practicing clinician should interpret and make use of this evidence.MethodsThe latest spine literature in the topic of reducing the surgical footprint for spine metastases was reviewed and clinical recommendations were formulated. The recommendations are dichotomously graded into strong and conditional based on the integration of scientific methodology and content expert opinion. This opinion considers experience and practical issues such as risks, burdens, costs, patient values, and circumstances.ResultsFour high impact studies were selected for review. The findings suggest that surgery plays a key role in improving patients' quality of life, but incidence of adverse events remains high and hence methods to decrease surgical morbidity are necessary. The integration of radiation into the treatment algorithm allows for less extensive surgical procedures and SBRT should be strongly considered after surgery for spine metastases in appropriate patient populations. Implementation of enhanced recovery after surgery (ERAS) protocols reduce perioperative morbidity for both open and minimally invasive surgeries and should be considered on an institutional level. Utilization of minimally invasive surgical stabilization should be considered as it results in fewer post operative complications, lower infection rates, less blood loss during surgery, and a shorter hospital stay compared to open stabilization of unstable pathology thoracolumbar fractures.ConclusionsThe role and benefits of surgery for metastatic spine disease are well established, yet surgery carries significant risk for adverse events which may negatively affect overall cancer care. Methods for reducing the surgical footprint include incorporation of stereotactic radiation allowing less extensive surgery, implementation of ERAS protocols and utilization of minimally invasive surgical strategies.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251352442"},"PeriodicalIF":2.6,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170550/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AO Spine Knowledge Forums Promote Collaboration and Elevate the Impact of Research: A Bibliometric Analysis.","authors":"Daniel N de Souza, David B Kurland, Luiz Vialle, Klaus J Schnake, Shekar N Kurpad, Stephen J Lewis, Gregory D Schroeder, Sangwook T Yoon, Stefano Boriani, Ziya Gokaslan, Laurence D Rhines, Arjun Sahgal, Charles Fisher, Ilya Laufer","doi":"10.1177/21925682251351012","DOIUrl":"10.1177/21925682251351012","url":null,"abstract":"<p><p>Study DesignBibliometric analysis.ObjectivesThis study used bibliometric analyses to characterize the effect of AO Spine Knowledge Forum (KF) participation on publication trends among members. We examined associations of membership in KF organizations with academic productivity, collaboration, and scientific impact.MethodsWe queried the Web of Science database for publications by members of KF Tumor (N = 58), KF Trauma and Infection (N = 45), KF Spinal Cord Injury (N = 38), KF Degenerative (N = 54), and KF Deformity (N = 55). Resulting metadata were exported; statistical and bibliometric analyses were performed using Python packages.ResultsOur query returned 24,267 articles by KF members, of which 18,804 were identified as relevant to respective organizational themes through an algorithmic analysis of titles and abstracts. These works, published between 1980 and 2025, included contributions from 67,895 authors. Research productivity, co-authorship among members (<i>P</i> < 0.001), unique institutional affiliations per article (<i>P</i> < 0.001), and international collaboration increased contemporaneously with the first KF formation (2010). A positive association was found between the number of KF authors per publication and source journal impact factor (<i>P</i> < 0.001). Term analysis highlighted research foci within each KF and influential publications were identified.ConclusionsThese findings suggest that formalization of researcher relationships and the research infrastructure and support provided by the KF model was associated with increased and more impactful research output and collaboration. The KF model could be applied in other organizations whose mission includes collaborative research. Methods used in this study are easily replicable and may be applied to investigate the impact of other professional organizations across various fields.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251351012"},"PeriodicalIF":2.6,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12165958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144293651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to Letter to the Editor Regarding the Article Entitled 'The Safety of Spinal Surgery in Patients over 80 Years of Age: Propensity Score Matching Study' by Bang C et al.","authors":"Chungwon Bang, Young-Hoon Kim","doi":"10.1177/21925682251352521","DOIUrl":"10.1177/21925682251352521","url":null,"abstract":"","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251352521"},"PeriodicalIF":2.6,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12165948/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144283592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigenda, 2025.","authors":"","doi":"10.1177/21925682251343890","DOIUrl":"10.1177/21925682251343890","url":null,"abstract":"","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251343890"},"PeriodicalIF":2.6,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12162521/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of Atypical Scoliosis Patterns Using X-ray Images Based on Fine-Grained Techniques in Deep Learning.","authors":"Yi Chen, Zhong He, Kenneth Guangpu Yang, Xiaodong Qin, Adam Yiu-Chung Lau, Zhen Liu, Neng Lu, Jack Chun-Yiu Cheng, Wayne Yuk-Wai Lee, Elvis Chun-Sing Chui, Yong Qiu, Xiaoli Liu, Xipu Chen, Zezhang Zhu","doi":"10.1177/21925682251349999","DOIUrl":"10.1177/21925682251349999","url":null,"abstract":"<p><p>Study DesignRetrospective diagnostic study.ObjectivesTo develop a fine-grained classification model based on deep learning using X-ray images, to screen for scoliosis, and further to screen for atypical scoliosis patterns associated with Chiari Malformation type I (CMS).MethodsA total of 508 pairs of coronal and sagittal X-ray images from patients with CMS, adolescent idiopathic scoliosis (AIS), and normal controls (NC) were processed through construction of the ResNet-50 model, including the development of ResNet-50 Coronal, ResNet-50 Sagittal, ResNet-50 Dual, ResNet-50 Concat, and ResNet-50 Bilinear models. Evaluation metrics calculated included accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for both the scoliosis diagnosis system and the CMS diagnosis system, along with the generation of receiver operating characteristic (ROC) curves and heatmaps for CMS diagnosis.ResultsThe classification results for the scoliosis diagnosis system showed that the ResNet-50 Coronal model had the best overall performance. For the CMS diagnosis system, the ResNet-50 Coronal and ResNet-50 Dual models demonstrated optimal performance. Specifically, the ResNet-50 Dual model reached the diagnostic level of senior spine surgeons, and the ResNet-50 Coronal model even surpassed senior surgeons in specificity and PPV. The CMS heatmaps revealed that major classification weights were concentrated on features such as atypical curve types, significant lateral shift of scoliotic segments, longer affected segments, and severe trunk tilt.ConclusionsThe fine-grained classification model based on the ResNet-50 network can accurately screen for atypical scoliosis patterns associated with CMS, highlighting the importance of radiographic features such as atypical curve types in model classification.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251349999"},"PeriodicalIF":2.6,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12162537/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Streamlining the Journey of Research Into Clinical Practice: Making Your Patients and Practice Flourish: When to Fuse? An Evidence Based Review of Treatment Strategies in Degenerative Spondylolisthesis.","authors":"Christopher T Martin, Luca Ambrosio, Juan P Cabrera, Xiaolong Chen, Jason Py Cheung, Waeel Hamouda, Hai V Le, Philip K Louie, Sathish Muthu, Hardeep Singh, Mohamed A R Soliman, Veranis Sotirios, Javad Tavakoli, Sven Y Vetter, Zorica Buser, Andreas K Demetriades, Ashish Diwan, Patrick C Hsieh, Amit Jain, Gianluca Vadalà, Charles G Fisher, S Tim Yoon","doi":"10.1177/21925682251336755","DOIUrl":"10.1177/21925682251336755","url":null,"abstract":"<p><p>Study DesignLiterature review.ObjectiveTo provide a concise review of outcomes of decompression and fusion (D + F) vs decompression (D) alone for degenerative lumbar spondylolisthesis (DLS).Methods6 articles were selected, including 3 randomized clinical trials (RCT), 2 meta-analyses, and 1 radiographic cohort study. Summarized factors affecting the outcomes of D + F vs D alone for DLS and provide expert level clinical recommendations.ResultsGhogawala included DLS patients showing improved SF-36 scores (<i>P</i> = 0.046) and lower re-operation rates (<i>P</i> = 0.05) in D + F patients compared to D alone. Forsth, included patients with stenosis both with and without DLS, and showed no difference in any reported outcome measure or reoperation rate. Austevoll included DLS patients that found that D alone was non-inferior to D + F in the primary outcome measure of ODI reduction at 2-year after surgery. Gadjradi included studies showing higher morbidity in the D + F group, as compared to D alone. Shukla included studies which found there was no difference in the raw patient outcome scores at final follow-up. Blumenthal included DLS patients who received D and reported disc height of >6.5 mm, facet angle >50°, and dynamic motion >1.25 mm were associated with high re-operation rates (45%, 39%, and 54% respectively).ConclusionsThe RCT's and meta-analyses report contradictory conclusions and no blanket statement regarding the efficacy of D + F vs D alone can be made for all patients with DLS. Surgeons should closely review pre-operative imaging for signs of instability in order to better identify appropriate patients for each indication.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251336755"},"PeriodicalIF":2.6,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12158961/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}