Frontiers in Pediatrics最新文献

{"title":"Mean nutrient adequacy ratio and associated factors of complementary foods among children aged 6-23 months in Northeast Ethiopia.","authors":"Abdulkerim Kassaw, Tefera Chane Mekonnen, Erkihun Tadesse Amsalu, Eyob Tilahun ABeje, Chala Daba, Yawkal Tsega, Abel Endawkie","doi":"10.3389/fped.2025.1446431","DOIUrl":"10.3389/fped.2025.1446431","url":null,"abstract":"<p><strong>Background: </strong>Inadequate intake of macro- and micronutrients is a significant public health challenge in Ethiopia. Ethiopia carries a substantial burden of both macro- and micronutrient deficiencies, with far-reaching consequences. However, there is limited evidence on the determinants and mean nutrient adequacy of complementary foods among children aged 6-23 months. Therefore, this study aims to determine the mean nutrient adequacy ratio and associated factors of complementary feeding among children aged 6-23 months in Northeast Ethiopia.</p><p><strong>Methods: </strong>A study was conducted in Northeast Ethiopia between 1 March and 30 April 2023, among 255 children aged 6-23 months. The study employed a systematic sampling technique to select 255 children. The data were collected using a 24-h dietary recall method. Linear regression analysis was conducted to identify factors associated with the nutrient adequacy of complementary foods. In the multivariable analysis, variables with <i>p</i>-values <0.05 were considered statistically significant.</p><p><strong>Results: </strong>The study found that the mean nutrient adequacy ratio of complementary foods among children aged 6-23 months in Northeast Ethiopia was 63% (95% CI 60.8-65.14). The adequacy of nutrients in complementary foods varied: energy (90%), fat (93%), carbohydrate (70%), protein (88%), calcium (57%), zinc (52%), vitamin B1 (50%), vitamin A (52%), and vitamin C (60%). The age of the child, mother's education, wealth index, feeding frequency, dietary diversity, minimum acceptable diet, source of information during antenatal care, postnatal care, food insecurity, and the number of children aged under 5 were associated with mean nutrient adequacy of complementary feeding.</p><p><strong>Conclusions: </strong>The study concludes that the mean nutrient adequacy ratio of complementary foods among children aged 6-23 months in Northeast Ethiopia is alarmingly low, indicating a significant gap in meeting the nutritional recommendations set by the World Health Organization. Various factors, including the child's age, maternal education, household wealth index, food insecurity, and dietary diversity, were identified as critical determinants of nutrient adequacy. These findings underscore the urgent need for comprehensive interventions at multiple levels, including education, food security, and health services, to enhance the consumption of adequate and diverse complementary foods. By addressing these factors, stakeholders can improve the nutritional status of young children, ultimately contributing to better health outcomes and development in the region.</p>","PeriodicalId":12637,"journal":{"name":"Frontiers in Pediatrics","volume":"13 ","pages":"1446431"},"PeriodicalIF":2.1,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925895/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bibliometric analysis of Crohn's disease in children, 2014-2024.","authors":"Yanjing Zhu, Yunhong Ma, Zhengjiu Cui, Yueli Pan, Juanjuan Diao","doi":"10.3389/fped.2025.1515251","DOIUrl":"10.3389/fped.2025.1515251","url":null,"abstract":"<p><strong>Background: </strong>In recent years, the incidence of Crohn's disease has risen significantly in the pediatric population, and its prolongation has had a major impact on children's physical and mental health as well as on the quality of life of their families, and has therefore received extensive attention from scholars around the world. A large number of articles have been published on Crohn's disease in children; however, there is still a lack of studies that use visualization methods for bibliometric analysis of relevant literature. The purpose of this paper is to statistically analyze the published literature in the field of Crohn's disease in children in order to help in the future diagnosis and treatment of Crohn's disease in children.</p><p><strong>Methods: </strong>Literature meeting the inclusion criteria was screened from the Web of Science Core Collection database. Literature was visualized and analyzed by author, country, institution, journal, reference, and keyword using Citespace (6.2.R4) and VOSviewer (1.6.18).</p><p><strong>Results: </strong>A total of 3,177 eligible publications were included. There is an overall increasing trend in the number of annual publications.Turner, Dan published the most number of articles with 78 and has a high impact in the field of CD. The most cited author was Levine, A. Among countries and institutions, the United States and Tel Aviv University had the highest number of publications. The journal with the most publications is Journal Of Pediatric Gastroenterology And Nutrition. The most co-cited journal was Inflammatory Bowel Diseases. The most cited document was ESPGHAN Revised Porto Criteria for the Diagnosis of Inflammatory Bowel Disease in Children and Adolescents, and the most cited document with the highest outbreak intensity was The Medical Management of Paediatric Crohn's Disease: an ECCO-ESPGHAN Guideline Update.The most frequent keyword was \"inflammatory bowel disease\".</p><p><strong>Conclusion: </strong>This study provides a visual summary of information for the field of pediatric Crohn's disease and contributes to international collaboration to promote research in the field of pediatric Crohn's disease.</p>","PeriodicalId":12637,"journal":{"name":"Frontiers in Pediatrics","volume":"13 ","pages":"1515251"},"PeriodicalIF":2.1,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11922724/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypoxemia detection and oxygen therapy practices in neonatal and pediatric wards across seven district and referral hospitals in Rwanda.","authors":"Hyacinthe Mushumbamwiza, Harriet H Webster, Christine Kayitesi, Jasmine Miller, Nang'andu Chizyuka, Felix Musabirema, Alida Ngwije, Brenda Kateera, Sanctus Musafiri, Lisine Tuyisenge, Hamish R Graham, Felix Lam, Corneille Ntihabose","doi":"10.3389/fped.2025.1526779","DOIUrl":"10.3389/fped.2025.1526779","url":null,"abstract":"<p><strong>Background: </strong>Hypoxemia, characterized by low levels of oxygen in the blood, is a potentially fatal condition that is commonly found in pediatric and neonatal conditions that drive childhood mortality globally. The only treatment is the provision of medical oxygen, yet children in low-income countries frequently are not diagnosed or treated. In Rwanda, it is important to understand the extent to which pediatric and neonatal inpatients are monitored and treated for hypoxemia, in order to guide policy and clinical decision-making.</p><p><strong>Methods: </strong>This retrospective cohort was undertaken through review of patient clinical case notes in seven hospitals in Rwanda. All patients, up to 14 years of age, admitted to neonatal or pediatric wards in these hospitals within a 3-month period were included in the study. In each facility, trained clinical data collectors used digital survey tools to capture demographic, clinical and outcome data, including pulse oximetry and oxygen use. Neonates were categorized as less than 1 month of age and under-5 s defined between 1 month and 59 months of age, and older children as 5-14 years of age. Our primary outcomes were proportion of admitted children screened with pulse oximetry, and proportion prescribed oxygen when found to be severely hypoxemic, on admission. Our secondary outcomes included hypoxemia prevalence, and other vital signs recorded on admission, oxygen prescription practices, and pulse oximetry screening practices on the day after admission and the day before discharge.</p><p><strong>Results: </strong>A total of 3,085 neonatal and pediatric patient case notes were included in the analysis. Of these inpatients 86.3% (CI: 95% 85.0-87.4) were screened with pulse oximetry on admission. Of those screened, 18.6% (CI: 95% 17.2-20.1) were documented to have severe hypoxemia (SpO₂ < 90%). Of 495 patients with documented severe hypoxemia on admission, 48.3% (CI: 95% 44.0-52.6) had an oxygen prescription recorded on admission, reaching 76.0% treated with oxygen across the course of their admission (CI: 95% 72.0-79.5).</p><p><strong>Conclusions: </strong>Improvements are required in management of hypoxemia in neonates and pediatric inpatients in Rwanda to ensure all patients are screened and those found to be hypoxemic are treated with medical oxygen.</p>","PeriodicalId":12637,"journal":{"name":"Frontiers in Pediatrics","volume":"13 ","pages":"1526779"},"PeriodicalIF":2.1,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11922911/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Twists and turns: spontaneous torsion of accessory liver lobe and gallbladder-diagnostic challenges and surgical interventions-a case report.","authors":"Soumaya Charaa, Julien Frandon, Ghizlane Touimi Benjelloun, Benoit Tessier","doi":"10.3389/fped.2025.1530918","DOIUrl":"10.3389/fped.2025.1530918","url":null,"abstract":"<p><p>An accessory liver lobe (ALL) represents a rare congenital variation of liver tissue, typically resulting from focal excessive development of liver tissue. Torsion of such lobes, though rare, can precipitate a severe surgical crisis due to hepatic ischemia and failure. We report a case involving a 9-year-old patient who was admitted with acute epigastric pain. Doppler ultrasound and contrast-enhanced CT scans revealed a heterogeneous, avascular mass with displacement of the gallbladder, which had a thickened wall. During laparotomy, a twisted, congested ALL along with the gallbladder was surgically removed. Diagnostic imaging, particularly computed tomography (CT), plays a crucial role in the rapid identification of causes behind acute abdominal pain, necessitating meticulous analysis of CT scans. We share the findings from imaging and surgery to enhance awareness of this rare condition.</p>","PeriodicalId":12637,"journal":{"name":"Frontiers in Pediatrics","volume":"13 ","pages":"1530918"},"PeriodicalIF":2.1,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11922709/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilization of ECMO with fiberoptic bronchoscopy for pediatric patients with lethal pulmonary hemorrhage unresponsive to conventional mechanical ventilation.","authors":"Siwei Lu, Yuelin Sun, Yingfu Chen, Yueqiang Fu, Jing Li, Chengjun Liu","doi":"10.3389/fped.2025.1547579","DOIUrl":"10.3389/fped.2025.1547579","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To evaluate the safety and efficacy of extracorporeal membrane oxygenation (ECMO) combined with fiberoptic bronchoscopy in children with life-threatening pulmonary hemorrhage that does not respond to conventional mechanical ventilation.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;From October 2019 to June 2022, four pediatric patients with life-threatening pulmonary hemorrhage requiring ECMO support were admitted to our hospital. Based on their weight and vascular conditions, either venoarterial (VA)-ECMO or venovenous (VV)-ECMO was selected. The anticoagulation strategy was tailored, and fiberoptic bronchoscopy was performed to assess airway bleeding and remove blood clots.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The study involved four patients. Case 1 sustained injuries from a traffic accident, Case 2 experienced combined injuries from a high fall, Case 3 had pulmonary vascular malformation, and Case 4 presented with anti-neutrophil cytoplasmic antibody-associated vasculitis. Case 1 underwent VA-ECMO with carotid artery and vein cannulation, whereas the other patients received VV-ECMO with jugular-femoral vein cannulation. During cannulation, heparin was administered at 0.5 mg/kg. Protamine was subsequently used to neutralize heparin based on the bleeding situation. Anticoagulation was initiated 24 h after ECMO commencement in Cases 1, 2, and 4, maintaining an activated clotting time (ACT) of 160-180 s. In Case 3, active bleeding was observed in the tracheal tube post-ECMO initiation. Protamine was administered to reverse the effects of heparin, and anticoagulation was withheld for the first 72 h. After a second interventional embolization of the vascular malformations, the active bleeding ceased. Two fiberoptic bronchoscopies revealed no further bleeding, and anticoagulation was initiated at 5 U/kg/h to maintain an ACT of 160 s. Coagulation parameters, including ACT, blood analysis, and thromboelastography, were closely monitored, and heparin dosages were adjusted accordingly. Heparin was paused 1 h before each fiberoptic bronchoscopy and resumed afterward. During ECMO, all patients successfully underwent fiberoptic bronchoscopy. Cases 2 and 3 required three and six procedures, respectively. Substantial thrombi were removed from the airways of Cases 2 and 3. All patients survived, and they were discharged without complications related to ECMO or fiberoptic bronchoscopy.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;For children with life-threatening pulmonary hemorrhage that did not respond to conventional mechanical ventilation, the combination of ECMO and fiberoptic bronchoscopy represents a promising therapeutic option. ECMO rapidly corrects hypoxemia and provides respiratory support, whereas fiberoptic bronchoscopy effectively clears blood clots and facilitates lung re-expansion. Under an individualized anticoagulation strategy, this combined approach is both safe and effective, significantly improving clinical outcomes in pediatric patie","PeriodicalId":12637,"journal":{"name":"Frontiers in Pediatrics","volume":"13 ","pages":"1547579"},"PeriodicalIF":2.1,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11922937/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical characteristics of patients with atypical teratoid/rhabdoid tumors: a monocentric retrospective analysis.","authors":"Zhiliang Wang, Jingchen Yang, Xing Liu, Wei Liu","doi":"10.3389/fped.2025.1463510","DOIUrl":"10.3389/fped.2025.1463510","url":null,"abstract":"<p><strong>Purpose: </strong>Atypical teratoid/rhabdoid tumors (ATRTs) are very rare, highly malignant embryonal neoplasms in central nervous system. The aim of this study was to conduct a retrospective analysis of ATRT patient survival and investigate the prognostic factors associated with ATRT.</p><p><strong>Methods: </strong>A retrospective study was conducted using information of patients who received treatment between 2016 and 2021 in Beijing Tiantan Hospital. Kaplan-Meier curves were used for overall survival (OS) analysis. Univariate and multivariate COX analyses were applied for OS predicting.</p><p><strong>Results: </strong>20 histologically confirmed ATRT patients were included. The majority were male (75%) and aged over 3 years (65%). 71.4% of patients under 3 years and 46.2% of above 3 years had supratentorial tumors. All patients underwent surgery, with 60% having total resections, primarily in the supratentorial region. Subsequent treatment involved varying chemotherapy and radiation combinations, with 40% of patients receiving it, and 87.5% of those were older than 3 years, The median overall survival for ATRT patients was 180 days. Survival differed significantly between patients under and above 3 years. Radiotherapy increased overall survival for all patients. Univariate and multivariate analysis showed better survival for those diagnosed above age 3 and with adjuvant radiation.</p><p><strong>Conclusions: </strong>Patients older than 3 years old had better prognosis and radiotherapy had a significant effect on improving patient prognosis.</p>","PeriodicalId":12637,"journal":{"name":"Frontiers in Pediatrics","volume":"13 ","pages":"1463510"},"PeriodicalIF":2.1,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11922728/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical value of Beery visual-motor integration and Beery VMI supplemental tests in Chinese preschoolers: a modified replication cross-sectional study.","authors":"Xin Tang, Xuan Xu, Cong Wang, Lijuan Ao","doi":"10.3389/fped.2025.1531192","DOIUrl":"10.3389/fped.2025.1531192","url":null,"abstract":"<p><strong>Objective: </strong>Previous studies have indicated that visual-motor performance is affected by cultural variations. This study aimed to examine differences between the proportion of children with poor visual-motor integration (VMI) performance in published population norms with that in the sample population of this study and to assess the predictive value of the visual perception(VP) and motor coordination(MC) scores in explaining VMI variance in Chinese preschoolers.</p><p><strong>Methods: </strong>A random sample of 421 children ageds 3.0-6.11 years (mean age, 4.51 ± 0.93) participated in this study. The Beery VMI, VP, and MC were administered in sequence by qualified raters.</p><p><strong>Results: </strong>The standard scores of VMI in all age groups of this study were significantly better than those in U.S. norms. Overall, 61 (14.5% of the total sample) and 6 (1.4% of the total sample) children did poorly in the VMI test using study population norms and published population norms, respectively. The proportion of children with poor VMI performance using published norms was significantly lower compared with that using study sample population norms (<i>p</i> < 0.001). Multiple regression analysis showed that VP and MC were significantly related to the VMI (VP: <i>β</i> = 0.185, <i>p</i> < 0.001; MC: <i>β</i> = 0.400, <i>p</i> < 0.001) and 25.0% (<i>F</i> = 69.571, <i>dF</i> = 2, <i>p</i> < 0.001) variance of VMI could be explained by VP and MC.</p><p><strong>Conclusion: </strong>Our findings support that the effects of culture should be considered when interpreting the results of Beery VMI using published norms, especially in poor performance diagnosis. Our findings further support that three tests should be assessed individually during the visual perception examination regardless of cultural context. Chinese preschooler-based norms need to be established in future investigations to determine the diagnostic value of the Beery VMI.</p>","PeriodicalId":12637,"journal":{"name":"Frontiers in Pediatrics","volume":"13 ","pages":"1531192"},"PeriodicalIF":2.1,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11922713/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measuring attraction to screen devices in early childhood: development of the Affinity-TV and Affinity-Mobile scales.","authors":"Darcy A Thompson, Laura K Kaizer, Sarah J Schmiege, Natasha J Cabrera, Lauren Clark, Haley Ringwood, Estefania Miramontes Valdes, Jeanne M Tschann","doi":"10.3389/fped.2025.1496225","DOIUrl":"10.3389/fped.2025.1496225","url":null,"abstract":"<p><strong>Introduction: </strong>With the increasing integration of digital screen devices into our everyday life, there has been increased attention regarding the risk of \"problematic\" use or pathological use. Because children start using screen devices in the first few years of life, early identification of those at risk for future problematic use could inform early prevention efforts. Children's attraction to screen devices in early childhood may identify those at risk for future problematic use; however currently, there are no measures of toddlers' attraction or affinity to screen devices. The objective of this study was to develop survey measures of toddler affinity to screen media, inclusive of televisions, smartphones, and tablets.</p><p><strong>Methods: </strong>Measures were developed using an exploratory sequential mixed methods (qualitative -> quantitative) approach. Participants were Mexican American mothers of toddlers 15-26 months old. Findings from semi-structured interviews were used to develop items reflecting parental reports of child affinity to screen devices. Items were administered by phone to 384 mothers. Analyses included evaluation of the factor structure and psychometric properties of Affinity-TV (10 items) and Affinity-Mobile (12 items), and evaluations of correlations between each scale with social emotional outcomes and demographic characteristics.</p><p><strong>Results: </strong>Factor analysis supported a one-factor solution for each scale. Reliabilities were acceptable for both scales (Cronbach's alpha > .75). There was a significant positive correlation between Affinity-TV and Affinity-Mobile (rs = 0.44, <i>p</i> < 0.001). Affinity-TV was significantly positively correlated with toddler average daily minutes of TV use (rs = 0.27, <i>p</i> < 0.001) and average daily minutes of mobile use (rs = 0.10, <i>p</i> < 0.05). Affinity-Mobile was significantly positively correlated with toddler average daily minutes of mobile use (rs = 0.31, <i>p</i> < 0.001), but not with average daily minutes of TV (rs = -0.04, NS). Each scale was correlated with social emotional developmental outcomes.</p><p><strong>Discussion: </strong>The Affinity-TV and Affinity-Mobile scales have good initial reliability and adequate predictive validity. These findings support the use of Affinity-TV and Affinity-Mobile in toddlers as measures of children's attraction to screen devices. These measures may help to identify early risk for problematic use, and they offer a novel way to evaluate a child's behavioral reaction to screen devices in early childhood.</p>","PeriodicalId":12637,"journal":{"name":"Frontiers in Pediatrics","volume":"13 ","pages":"1496225"},"PeriodicalIF":2.1,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11919659/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early detection of risks in child development in Spanish-speaking countries: content validity.","authors":"Luis Felipe Llanos, María Martínez de Anguita","doi":"10.3389/fped.2025.1444104","DOIUrl":"10.3389/fped.2025.1444104","url":null,"abstract":"<p><strong>Introduction: </strong>Early detection of developmental disorders like ADHD, ASD, and LD is critical for improving educational outcomes and enabling timely interventions. This study aimed to develop a reliable, practical screening scale for Spanish-speaking children entering primary education, addressing gaps in early identification within the region.</p><p><strong>Methods: </strong>In total, 151 items were identified. With a qualitative methodology and with the help of 18 specialists in child therapy from various Spanish-speaking countries, stabilized content validity. The analysis was articulated in its aspects of relevance.</p><p><strong>Results: </strong>The validation process identified 18 items with strong psychometric properties. These items demonstrated high levels of agreement among experts and strong content validity, forming the foundation for a culturally relevant screening tool. The scale is designed to identify developmental risks early and support timely interventions in educational and clinical settings.</p><p><strong>Discussion: </strong>The study underscores the importance of efficient screening tools for primary education, especially in regions with limited access to early childhood education. Future research will validate the scale in larger, diverse samples to ensure its reliability, establish cutoff points, and confirm its generalizability across Spanish-speaking contexts.</p>","PeriodicalId":12637,"journal":{"name":"Frontiers in Pediatrics","volume":"13 ","pages":"1444104"},"PeriodicalIF":2.1,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11919850/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of children with severe preschool asthma prior to starting the TIPP study.","authors":"S Zielen, J Wosniok, N Wollscheid, T Nickolay, C Grimmel, D Scheele, F Sattler, F Prenzel, M Lorenz, B Schaub, C Lex, M Dahlheim, J Trischler, H Donath, S Lau, E Hamelmann, C Vogelberg, M Gerstlauer, M Wetzke, R Schubert, L Schollenberger, M Gappa","doi":"10.3389/fped.2025.1558256","DOIUrl":"10.3389/fped.2025.1558256","url":null,"abstract":"<p><strong>Objective: </strong>Children with preschool asthma suffer disproportionally more often from severe asthma exacerbations with emergency visits and hospital admissions than school children. However, there are only a few reports on characteristics, hospitalization, phenotypes and symptoms in this age cohort.</p><p><strong>Patients and methods: </strong>This analysis of an ongoing prospective trial of Tiotropium bromide in preventing severe asthma exacerbations (the TIPP study) assessed baseline characteristics, hospitalizations and symptoms in 100 children with severe preschool asthma. Children aged 1-5 years were analyzed at study enrollment and daily symptoms were recorded by an electronic diary [Pediatric Asthma Caregiver Diary (PACD)] for the following four weeks until randomization.</p><p><strong>Results: </strong>At enrollment, the total number of severe asthma exacerbations, defined as three days systemic steroid use or hospitalization in the last 24 months, was mean (±SD) 5.8 ± 5.7 and the test for respiratory and asthma control in kids (TRACK) was mean 46.9 ± 19.0. Daily recording of symptoms by the PACD revealed that only 7 patients were controlled at randomization, whereas 35 were partially and 58 were uncontrolled according to GINA.</p><p><strong>Conclusion: </strong>Despite protective therapy with inhaled corticosteroids (ICS), most children of this severe asthma cohort were only partially or uncontrolled according to GINA guidelines.</p>","PeriodicalId":12637,"journal":{"name":"Frontiers in Pediatrics","volume":"13 ","pages":"1558256"},"PeriodicalIF":2.1,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11921963/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}