Georgian medical news最新文献

{"title":"ORAL MANIFESTATIONS IN JUVENILE SCLERODERMA: CLINICAL PRESENTATIONS AND HISTOPATHOLOGICAL CHARACTERISTICS.","authors":"A Skakodub, M Osminina, N Geppe, O Admakin, Y Kozlitina, A Goryaynova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Juvenile scleroderma (JS) is a rare chronic connective tissue disorder characterized by stiffening of the skin and soft tissues, including the oral cavity and perioral tissues, leading to fibrosis and a large spectrum of internal organs involvement, cosmetic defects, and early infant disability. The aim of this study was to investigate the histomorphological features of lesions of oral mucosa tissues in children with juvenile scleroderma (JS). 39 JS patients (9 with juvenile systemic sclerosis - JSS and 20 with juvenile scleroderma of head-JSH aged from 5 to 17 years were observed with dental examination and morphological investigation of the dental mucosa. The oral mucosa in patients with JS showed signs of damage of the mucous membrane of the oral cavity, was detected in 100% of JS patients observed. Lesions of mucosa appear at the earliest stages of the disease and are associated with the development of dystrophic and atrophic processes, and abnormal vascularization. In 72.63% of patients, C3 deposition of the complement component and IgM and IgG containing immune complexes were found in the vessel walls of the oral cavity. Vasculitis of the oral cavity was detected among 1/3 of patients, and vasculopathy was found among 52,63 % of those examined. Mucosal, dystrophic, and vascular abnormalities develop in children with JSS, as well as in JSH patients. We distinguish and describe four stages of mucous lesions. Secondary infection stomatitis was noticed in patients.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 356","pages":"74-81"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143038037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CLINICAL AND LABORATORY PREDICTORS OF ADVERSE OUTCOME WITH SEVERE COVID-19 IN COMORBID PATIENTS OF THE KARAGANDA REGION, REPUBLIC OF KAZAKHSTAN.","authors":"Y Li, Y Zhunussov, B Kosherova, G Placinta, B Tulegenova","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Aim of the study: </strong>Analysis of clinical, laboratory and instrumental parameters in comorbid patients with severe COVID-19.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on clinical, laboratory and instrumental parameters in patients with laboratory-confirmed severe COVID-19 taking into account the treatment outcome (recovery or lethal outcome). A multifactor logistic regression model was utilized to identify factors influencing lethal outcome in patients with severe COVID-19.</p><p><strong>Results: </strong>Patients with lethal severe COVID-19 had a lower rate of coronavirus vaccination and more frequent dyspnea compared to patients with a favorable prognosis. Additionally, blood oxygen saturation during hospitalization was lower in cases of unfavorable outcomes than in cases of favorable outcomes, and the extent of lung tissue damage was subtotal in most cases. The changes in laboratory parameters during therapy in patients with favorable and unfavorable outcomes were diverse and reflected the disease progression. According to the highly sensitive and specific developed multifactor logistic regression model, three key indicators significantly affecting the likelihood of lethal outcomes in severe COVID-19 patients are the presence of cerebrovascular diseases, and elevated levels of C-reactive protein and lactate dehydrogenase.</p><p><strong>Conclusions: </strong>The findings from the comprehensive analysis of clinical and laboratory parameters revealed the main predictors of unfavorable outcomes in severe COVID-19 cases: the presence of cerebrovascular diseases, and elevated levels of C-reactive protein and lactate dehydrogenase.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 356","pages":"124-129"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143037859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IMPORTANCE AND URGENCY OF TREATMENT AND PREVENTION STRATEGIES OF COMPLICATIONS IN ORTHODONTIC PATIENTS - LITERATURE REVIEW.","authors":"M Nikuradze, Z Artmeladze, A Margvelashvili, V Margvelashvili, M Kalandadze","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>During orthodontic treatment patients' oral condition changes, thus influencing the overall health. Therefore, the treatment approaches require regular revision and updates to new guidelines. This literature review aims to analyse the oral health status in orthodontic patients focusing on the importance and urgency of treatment, preventive approaches to complications, and effects of the appliances on the oral biome. The review used Google Scholar, PubMed, and Science Direct databases for article searches dating from 2000 to 2024 on the status of the oral cavity changes during orthodontic treatment. Results have shown that changes in the oral cavity do not depend on the type of orthodontic appliances, both qualitative and quantitative changes in the bacterial flora were detected in cases of using all types of appliances. Orthodontic appliances and treatment may deteriorate overall oral hygiene in patients, particularly when patients practice poor oral hygiene habits, increasing the risks of developing dental decays and periodontal diseases.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 356","pages":"118-123"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143038004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"STRATEGIES FOR IMPROVING PSYCHOLOGICAL COMPETENCE IN PHYSICAL REHABILITATION.","authors":"V Baltian, E Manzhalii Christian, L Volnova, Yu Rohalya, O Borysova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The study aims to analyse strategies for improving psychological competence in physical rehabilitation. The research was conducted using a mixed type, which involved the analysis of qualitative and quantitative data. The PRISMA approach was used to collect qualitative data. The inclusion of scientific sources involved the following 4 criteria: 1. Focus on rehabilitation, psychology, or resilience. 2. Published in peer-reviewed journals. 3. Includes process of data or methods. 4. Written in English. Semi-structured interviews were also conducted with five experts. Semi-structured interviews were chosen because they are flexible and dynamic. Transcription of the recorded interviews and coding and comparative analysis were used to analyse the data. Acquiring psychological competencies is essential for medical staff, resulting from changes in attitudes towards patients and their mental and emotional states. Among the modern strategies for improving psychological competence are cognitive behavioural therapy, support for the emotional state (empathy), psychodiagnostics and work on self-esteem, social support, psychoeducation, and work on motivation. The identified strategies have a reasonably quick effect, are long-lasting, and require the involvement of additional specialists. Taking into account experts' opinions made it possible to establish the importance of focusing on modern rehabilitation on the psychological recovery of patients, which is as important as physical recovery.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 356","pages":"42-49"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143038091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"VIRTUAL ENVIRONMENTS AND HUMAN ANATOMY LEARNING ACHIEVEMENTS IN UNIVERSITY STUDENTS.","authors":"M Florencio, M Muñoz, Y Cruz, S Álvarez, M Rubio, E Prudencio, W Gomez-Gonzales","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Virtual learning is characterized by the fact that the sender and the receiver are not present in the development of the learning sessions or in the same physical space; it can be synchronous or asynchronous. In certain subjects such as Human Anatomy, the teaching was face-to-face, which is why the question arose whether the virtual teaching of human anatomy was effective or ineffective.</p><p><strong>Objective: </strong>To determine the relationship between virtual environments and learning achievements in the subject of human anatomy in students of a Peruvian university during the COVID-19 pandemic.</p><p><strong>Methods: </strong>Quantitative, descriptive correlational study, 187 undergraduate students participated in the Human Anatomy subject of the Faculty of Human Medicine of the Universidad Nacional Mayor de San Marcos. The virtual survey was used as a technique and a Likert-type scale as an instrument, whose content validity coefficient was 0.9062 and reliability, applying Cronbach's Alpha, was 0.956.</p><p><strong>Results: </strong>Of 100% (187), 82.9% (155) of the respondents considered the virtual environment favorable and 17.1% (32) considered it unfavorable. Of those who responded favorably, the learning achievement was considered: Good 53.5% (100); regular 21.4% (40); greater 6.4% (12) and minimum 1.6% (3). The virtual environment and learning achievements are related according to Pearson=7.785, p value=0.051 less than ɑ=0.10 and there is a moderate association with Cramer's V 0.204.</p><p><strong>Conclusions: </strong>There is a moderate association between the virtual environment and the learning achievement of the subject of human anatomy.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 356","pages":"161-164"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143038112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"INTRAORAL SCANNERS AND CONVENTIONAL IMPRESSIONS: A LITERATURE REVIEW.","authors":"G Muçolli, F Nikç, G Muçolli","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Using digital technology, respectively the use of intraoral scanners has increased exponentially in recent years. Intraoral scanners have gained traction and widespread use in the field of dental prosthetics and orthodontics. While the use of these digital devices enables the detection of visible areas of error in order to allow clinicians to correct those areas immediately without a need of restarting the entire process from the beginning as it should be done in the conventional method and subsequent procedures. While intraoral scanners provide notable benefits in terms of efficiency, accuracy, and patient comfort, they do come with certain drawbacks. The high initial cost, along with the ongoing expenses for maintenance and software updates, can place a financial strain on many dental practices. Additionally, there is a learning curve associated with mastering these devices, and certain clinical situations-such as limited mouth openings or areas that are difficult to scan-can pose challenges to their effectiveness. Accuracy may also be affected by factors like patient movement, insufficient salivation, or the presence of reflective or dark surfaces. Moreover, issues related to software compatibility, extended chair time in complex cases, and the need for multiple scanning attempts can reduce some of the time-saving advantages. Intraoral scanners also raise concerns about data security and patient privacy, and technical issues or system failures can disrupt clinical workflows. While intraoral scanners are undoubtedly valuable in modern dentistry, it is important for clinicians to carefully evaluate these limitations to ensure their effective integration into practice.</p><p><strong>Aim of study: </strong>Acquaintance with intraoral scanners, understanding the way they're used, advantages and disadvantages, differences with the convenctional method of impression, familiarity with the materials of impression measurement.</p><p><strong>Material and methods: </strong>This study was conducted as a literature review, using the latest literature on intraoral scanners and their use in dentistry, disadvantages and advantages over conventional impressions. Analysis of scientific papers published in online databases such as PUBMED and MEDLINE, EBSCO, Google Schoolar, using the keywords \"Intraoral scanners, convenctional impression, impressions, digital dentistry\".</p><p><strong>Conclusion: </strong>Intraoral scanners present tremendous comfort in the field of prosthodontics. When comfort is mentioned, it is worth emphasizing the advantages of working with an intraoral scanner, where the benefits are the same for both parties, patients and clinicist. Therefore, it is very important that in this period where technology is closely related with new and modern methods not only for taking impressions, but also for other procedures.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 356","pages":"94-99"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143037947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"APPLICATION OF IMPROVED AUTODERMOPLASTY TECHNIQUE IN GRANULATING WOUNDS TREATMENT.","authors":"N Andasbekov, N Omarov, S Imangazinov, Y Kairkhanov, O Tashtemirova, R Kazangapov, S Imangazinova, A Masalov","doi":"","DOIUrl":"","url":null,"abstract":"&lt;p&gt;&lt;p&gt;This prospective study was conducted at the Department of Surgery of the Pavlodar branch of the NCJSC \"SMU\" (Non-profit joint-stock company \"Medical University of Semey\" based on the city hospital No. 1, surgical hospital of Pavlodar, Kazakhstan.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Purpose: &lt;/strong&gt;The purpose of research is to evaluate the results of improved autodermoplasty technique for granulating wounds of different origin.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Study design: &lt;/strong&gt;Non-randomized controlled clinical trial Material and methods: The study included a total of 100 patients with granulating purulent wounds of various origins aged 20 to 70 years. In the period from 2022-2024. The average age was 41.03±1.14 years. In the main group, 50 patients with granulating wounds were treated using an improved technique of free split autodermoplasty. The study also included a comparison group, represented by 50 patients who underwent traditional local treatment of wounds after autodermotransplantation using wet-drying gauze dressings impregnated with antiseptic agents. To include patients in the study groups regarding the state of the wound surface before autodermoplasty, the following criteria were selected: wounds of various origins with active granulation and the presence of signs of marginal epithelialization after complete cleansing of the wound surface from purulent-necrotic tissues. The wound surface areas ranged from 50 to 200 cm2. Accordingly, the criteria for excluding patients from the study regarding the state of the wound surface were patients with flaccid granulation of wounds, the presence of purulent-necrotic tissues, and the absence of marginal epithelialization. Informed consent was obtained from all patients to participate in the study.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Surgical diseases with the occurrence of purulent wounds accounted for 25%, of which after the treatment of phlegmon - 10 (40%) cases, abscesses - 6 (24%), suppuration of postoperative wounds - 9 (36%) cases. Burn wounds of the IIIb degree occurred in 45%, wounds of traumatic origin 18% and frostbite of the III degree in 12%. The bottom of the wounds was represented by muscles and subcutaneous fat tissue. The engraftment rate of autodermal grafts relative to the initial area of the transplanted skin flap for surgical, burn and traumatic wounds in the main group of patients was 97.15±0.28%, 95.35±0.28% and 96.89±0.37%, respectively, which corresponded to the criterion of complete engraftment. For frostbite wounds, it was 81.2±1.14%, which was assessed as partial engraftment. In the comparison group, in surgical, burn and traumatic wounds, the degree of engraftment of autodermal grafts relative to the initial area of the transplanted skin flap was characterized as partial engraftment (78.75±0.41%, 76.0±0.28%, 80.0±0.9%, respectively), and as non-engraftment - in wounds due to frostbite (50.0±0.58%). After autodermoplasty of granulating wounds in 100 patients, wound complications were observed in 14 ","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 356","pages":"171-175"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143037917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EVALUATION OF VITAMIN D LEVEL IN SERUM OF PATIENTS WITH VITILIGO.","authors":"F Abdul-Reda, M Al-Zobaidy","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Vitamin D deficiency promotes initiation and sustainment of numerous medical disorders, including cancer, diabetes mellitus, autoimmune disorders, and cardiovascular diseases. The expression of vitamin D receptors by melanocytes suggests a role for it in controlling their physiology.</p><p><strong>Aim: </strong>Therefore, the aim of this study was to compare serum vitamin D levels in patients with vitiligo and normal healthy individuals.</p><p><strong>Material and methods: </strong>A cross-sectional study conducted in the Dermatology out-patient clinic at AL-Diwaniyah Teaching Hospital, Iraq, from January 2024 to October 2024. The study involved 50 vitiligo patients (24 males and 26 females) and 50 apparently healthy subjects as controls. The diagnosis of patients was based on clinical presentation and the results of Wood's light examination made by dermatologist. The serum levels of vitamin D were measured and categorized into normal, insufficient and deficient. Statistical analysis was performed using the Statistical Package for Social Sciences (Version 26) and comparisons were done using Chi-squared and unpaired t-tests. Data is considered significant at P≤0.05.</p><p><strong>Results: </strong>The mean serum concentrations of vitamin D of patients and their controls were15.08±8.29 ng/ml and 20.17±9.05 ng/ml, respectively, (P<0.05). Furthermore, the proportions of individuals with insufficient and deficient vitamin D levels were significantly higher in vitiligo patients than in healthy controls (P<0.05).</p><p><strong>Conclusion: </strong>Vitamin D concentrations are insufficient in Iraqi people, in general, and in vitiligo patients, in specific. However, the exact mechanism(s) of this association needs to be established for the introduction of this vitamin in the treatment of vitiligo.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 356","pages":"100-102"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143037923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ORAL HEALTH OF CHILDREN IN MY COUNTRY.","authors":"J Kotori, R Muqa, M Kotori","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Dental caries is the most prevalent chronic disease worldwide. It is a disease characterized by multifactorial etiology and slow evolution leading to the destruction of hard tooth tissue.</p><p><strong>Purpose: </strong>Throughout this article we aim to review some important aspects related to dental caries and the main etiological factors in order to gain knowledge for oral health professionals in the treatment and prevention of caries. At the same time, the purpose of this study is to assess the state of oral health of children in Kosovo.</p><p><strong>Material and methods: </strong>To conduct this study, we researched electronic databases, such as PubMed, Cochrane Library, ResearchGate, Science Direct, in selected scientific research and textbooks. Selection criteria included articles published from 1990 to 2021 describing the definition, etiology, and other characteristics associated with dental caries.</p><p><strong>Discussion: </strong>Tooth decay is a disease that develops through the gradual complex biological interactions of acidogenic bacteria, fermentable carbohydrates, tooth and saliva factors, as well as the time factor. Implementation of preventive measures, the need to invest in education for appropriate oral health maintenance measures, related to preventive and ongoing medical and dental care, are key to raising public awareness of its existence and contributing to reducing the prevalence of caries.</p><p><strong>Conclusion: </strong>Dental caries is a disease that can greatly affect the health and quality of life of patients, so it is extremely important to increase knowledge about treatment, focusing especially on preventive measures. However, educating and promoting oral health is essential.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 356","pages":"152-155"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143038024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"REGENERATIVE MATERIALS - THEIR INDICATIONS AND USE IN IMPLANTOLOGY: A LITERATURE REVIEW.","authors":"F Nikç, G Muçolli, G Muçolli","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>The primary objective of any implant system is to achieve firm fixation to the bone, which can be influenced by both biomechanical factors and biomaterial selection. An array of materials is used for the replacement of missing teeth through implantation. The appropriate selection of biomaterials directly influences the clinical success and longevity of implants. Therefore, clinicians need to have adequate knowledge of the various biomaterials and their properties for their judicious selection and application in clinical practice. Recent materials, such as bioceramics and composite biomaterials, which are under consideration and investigation, show a promising future. For optimal performance, implant biomaterials should have suitable mechanical strength, biocompatibility, and structural biostability in the physiological environment.</p><p><strong>Aim of study: </strong>The aim of this paper is to explain, through a review of the most current literature on regenerative materials, their indications, and their use in implantology: - The significance of these materials in surgical implant procedures, - The properties and indications of these materials, - The classification of natural and synthetic materials, - Their application in surgical procedures such as sinus lift, alveolar ridge augmentation, and implant placement.</p><p><strong>Material and methods: </strong>This article is a literature review in which the most current scientific and professional data on regenerative materials in implant dentistry are discussed and presented. The data for this paper were gathered from university textbooks, as well as articles published and archived in PubMed, Science Direct, Dental Products Report, and other sources.</p><p><strong>Conclusions: </strong>Bone grafts and substitute materials, which are either in particle or block form, are used in dentistry to regenerate missing hard tissue structures. There is a growing demand for new and more efficient grafting materials. Currently, bone grafts and substitute materials primarily serve as a structural scaffold for osteoregenerative processes, fulfilling the criteria of osteoconduction.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 356","pages":"130-135"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143038071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}