Georgian medical news最新文献_第3页

INCIDENCE AND CHARACTER OF SUBJECTIVE SLEEP DISORDERS IN THE GEORGIAN POPULATION OF CHILDREN AND ADOLESCENTS WITH AUTISM SPECTRUM DISORDER. 格鲁吉亚患有自闭症谱系障碍的儿童和青少年主观睡眠障碍的发生率和特征。

Georgian medical news Pub Date : 2025-06-01

N Nachkebia, Kh Bezhanishvili, N Maglakelidze, N Rogava, E Chkhartishvili, M Babilodze, M Shavgulidze, N Pipia, O Mchedlidze, V Tsomaia, I Khachidze, E Chijavadze

{"title":"INCIDENCE AND CHARACTER OF SUBJECTIVE SLEEP DISORDERS IN THE GEORGIAN POPULATION OF CHILDREN AND ADOLESCENTS WITH AUTISM SPECTRUM DISORDER.","authors":"N Nachkebia, Kh Bezhanishvili, N Maglakelidze, N Rogava, E Chkhartishvili, M Babilodze, M Shavgulidze, N Pipia, O Mchedlidze, V Tsomaia, I Khachidze, E Chijavadze","doi":"","DOIUrl":"","url":null,"abstract":"Aim of the study: This study aims to assess the incidence and characteristics of sleep disorders in children and adolescents with Autism Spectrum Disorder (ASD) in Georgia. This research is particularly relevant because ASD is a neurodevelopmental disorder, and one of its most challenging issues is sleep disorders. In Georgia, the number of children and adolescents with ASD has increased significantly over the past two decades, yet sleep disorders among this population have not been studied at all to date.Material and methods: The parents (volunteers) of 500 ASD children/adolescents (without comorbid conditions and medication-free) participated in this study. Children and adolescents with ASD who had sleep disorders were identified based on subjective data collected from their parents using a modified version of the Children's Sleep Habits Questionnaire, as well as the Simonds & Paraga modified version. The control group consisted of typically developing, age-matched peers. Results treated statistically by ANOVA, with Student's t criteria.Results and conclusion: For the first time, we discovered serious sleep disorders in 61% of Georgian children and adolescents with ASD characterized by: a) difficulties falling asleep, significant increases in sleep latency, and heightened sleep resistance; b) frequent awakenings and challenges in maintaining nighttime sleep; and c) a notable increase in anxiety and nightmares. All of these considerably worsen sleep quality, which can, in turn, have further consequences on the behavioral symptoms of ASD. The results will serve as diagnostic criteria for clinicians to prescribe personalized sleep therapy for each child or adolescent with ASD, in conjunction with behavioral therapy.","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 363","pages":"6-11"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144950745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

APPLICATION OF SHELL TECHNIQUE IN C-TIRADS COMBINED WITH STE IN DIAGNOSIS OF C-TIRADS GRADE 4-5 NODULES. c-tirads壳体技术结合超声诊断4-5级c-tirads结节的应用。

Georgian medical news Pub Date : 2025-06-01

Bi-Yun Sun, Wei Peng

{"title":"APPLICATION OF SHELL TECHNIQUE IN C-TIRADS COMBINED WITH STE IN DIAGNOSIS OF C-TIRADS GRADE 4-5 NODULES.","authors":"Bi-Yun Sun, Wei Peng","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To analyze the diagnostic value of the Shell technique in the Chinese Thyroid Imaging Reporting and Data System (C-TIRADS) combined with Shear Wave Elastography (STE) for differentiating benign and malignant C-TIRADS grade 4-5 nodules.Methods: A retrospective analysis was performed on 279 patients (with a total of 286 C-TIRADS grade 4-5 nodules) who underwent thyroid fine-needle aspiration biopsy (FNA) or surgery. Nodules were differentiated as benign or malignant using C-TIRADS classification, STE, and their combination. Taking cytopathological or postoperative pathological diagnosis as the gold standard, Receiver Operating Characteristic (ROC) curves were plotted, and the Area Under the Curve (AUC), sensitivity, specificity, accuracy, positive predictive value (PPV), and negative predictive value (NPV) were calculated to compare the diagnostic efficacy.Results: Pathological results showed that among 286 nodules, 94 were benign and 192 were malignant. C-TIRADS diagnosed 122 benign and 164 malignant nodules; STE diagnosed 115 benign and 171 malignant nodules; the combination diagnosed 108 benign and 178 malignant nodules. The AUC of the combined diagnosis for C-TIRADS grade 4-5 nodules was significantly larger than that of C-TIRADS classification and STE alone (Z=5.195, P<0.001; Z=3.602, P<0.001). The sensitivity of the combined diagnosis was higher than that of C-TIRADS classification and STE alone (χ²=8.649, P=0.003; χ²=5.488, P=0.019). The accuracy of the combined diagnosis was higher than that of C-TIRADS classification and STE alone (χ²=11.457, P<0.001; χ²=9.527, P=0.002). The NPV of the combined diagnosis was higher than that of C-TIRADS classification and STE alone (χ²=6.685, P=0.010; χ²=4.997, P=0.025).Conclusion: Compared with single application, C-TIRADS combined with the Shell technique in STE significantly improves the diagnostic sensitivity, accuracy, and NPV for C-TIRADS grade 4-5 thyroid nodules, demonstrating certain clinical application value.","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 363","pages":"18-22"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144950811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COMPARATIVE STUDY OF ANTIBACTERIAL EFFECTS OF MODIFIED PREPARATIONS CONTAINING METAL NANOPARTICLES. 含金属纳米颗粒改性制剂抑菌效果的比较研究。

Georgian medical news Pub Date : 2025-06-01

D Myrzakozha, T Issabekova, N Rakhymbayev, E Karlova, E Nechepurenko

引用次数: 0

KNOWLEDGE, ATTITUDE, AND PRACTICE TOWARD PROSTATE CANCER AND ITS SCREENING METHODS IN QASSIM REGION. 卡西姆地区对前列腺癌及其筛查方法的认识、态度和实践。

Georgian medical news Pub Date : 2025-06-01

A Altwairgi, F Al-Harbi, A Alayed, A Almoshigeh, E Aloadah, R Alkhalifah, B Alharbi

{"title":"KNOWLEDGE, ATTITUDE, AND PRACTICE TOWARD PROSTATE CANCER AND ITS SCREENING METHODS IN QASSIM REGION.","authors":"A Altwairgi, F Al-Harbi, A Alayed, A Almoshigeh, E Aloadah, R Alkhalifah, B Alharbi","doi":"","DOIUrl":"","url":null,"abstract":"Objective: Prostate cancer is a significant health concern globally, and in Saudi Arabia, it is the sixth most prevalent type of cancer among adult males over the age of 75. However, awareness and attitudes towards prostate cancer screening vary widely. This study aimed to assess the knowledge, attitudes, and practices (KAP) regarding prostate cancer and its screening methods in the Qassim region of Saudi Arabia.Methods: This descriptive cross-sectional study involved 384 male participants aged 20 years and above. Data were collected using an online Arabic questionnaire. Knowledge scores were calculated, and participants were classified as having good or poor knowledge. The Chi-squared test and Spearman's correlation analysis were used for statistical analysis.Results: Most participants (42.8%) were aged 20-29 years, and 90.3% were Saudi nationals. Only 61.6% had heard of prostate cancer, and 30.4% were aware of both the prostate-specific antigen (PSA) blood test and rectal exam. Knowledge about risk factors was poor, with smoking identified by 42.3% and obesity by 23.9%. Symptoms were better recognized, with 67.9% identifying blood in urine or semen. Only 10.9% had ever had a prostate exam, and 6.3% had a PSA test. Knowledge was significantly associated with age, educational level, occupational status, and working in the health-care field.Conclusion: The study revealed gaps in knowledge, attitudes, and practices regarding prostate cancer and its screening methods. Region-specific public health education strategies, particularly focusing on men under 40 and those outside health-care professions, are urgently needed.","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 363","pages":"205-211"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144950765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COMPARISON QUALITY OF LIFE BETWEEN THORACOSCOPIC SURGERY AND TRADITIONAL SURGERY IN THE TREATMENT OF CONGENITAL DIPHRAGMAL HERNIA IN NEWBORNS. 胸腔镜手术与传统手术治疗新生儿先天性膈疝的生活质量比较。

Georgian medical news Pub Date : 2025-06-01

F Huseynov, A Gasimov

{"title":"COMPARISON QUALITY OF LIFE BETWEEN THORACOSCOPIC SURGERY AND TRADITIONAL SURGERY IN THE TREATMENT OF CONGENITAL DIPHRAGMAL HERNIA IN NEWBORNS.","authors":"F Huseynov, A Gasimov","doi":"","DOIUrl":"","url":null,"abstract":"The aim of the study was to study the effectiveness of surgical treatment using a new minimally invasive thoracoscopic surgical technique in newborns with diaphragmatic hernia based on questionnaire demand. The study included 70 newborns with pathology. Depending on the method of surgical intervention, the children were divided into 2 groups. The 1st group consisted of 44 newborns with congenital diaphragmatic hernia, operated on using the traditional open method. The 2nd main group consisted of 26 newborns with similar pathology, operated using a minimally invasive new type of surgical technique - endosurgery. Before and after the operation, both the parent and the doctor filled out a questionnaire based on the QUALIN questionnaire. According to the results of the questionnaire, an improvement in all indicators in the postoperative period was noted in the main and control groups. Also, in the main group, all parameters were high according to both parents and doctors. However, statistical reliability was achieved for the parameters \"Ability to live independently\" and \"Neurological and mental development\". This also shows that the surgical treatment of diaphragmatic hernia in newborns that we proposed leads to a rapid improvement in the general condition of children and an intensification of the healing process, thereby bringing further development closer to normal indicators.","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 363","pages":"145-149"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144950862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

INTRA-OPERATIVE ASSESSMENT OF TIBIAL PLATEAU FRACTURE REDUCTION IN LOW-RESOURCE SETTINGS. 低资源环境下胫骨平台骨折复位术中评估。

Georgian medical news Pub Date : 2025-06-01

U Mahajan, M Akhtar, A Sain, A Raza, M Yousaf, A Afridi, B Ahmad, M Kabary, A Nasir, M Mohamed, H Manyar, H Hathaway, V Deshmukh

{"title":"INTRA-OPERATIVE ASSESSMENT OF TIBIAL PLATEAU FRACTURE REDUCTION IN LOW-RESOURCE SETTINGS.","authors":"U Mahajan, M Akhtar, A Sain, A Raza, M Yousaf, A Afridi, B Ahmad, M Kabary, A Nasir, M Mohamed, H Manyar, H Hathaway, V Deshmukh","doi":"","DOIUrl":"","url":null,"abstract":"Aim of the study: To summarize current intra-operative techniques for assessing tibial plateau fracture reduction, with a particular focus on their feasibility and applicability in low-resource settings.Material and methods: This narrative review synthesizes literature describing intraoperative assessment strategies for tibial plateau fractures. Although no single study specifically addressed reduction assessment in low-resource environments, relevant articles discussing imaging-based assessments (e.g. fluoroscopy, 3D imaging), direct visualization approaches (e.g. arthrotomy), and tactile reduction techniques were included based on clinical relevance and applicability.Results: Conventional 2D fluoroscopy remains the most widely used intraoperative imaging modality, despite its limited sensitivity for subtle articular incongruities. Direct visualization techniques, including arthrotomy, provide reliable tactile and visual assessment without requiring advanced imaging. Emerging innovations such as smartphone-assisted tools and 3D printing hold promise but currently lack validation in low-resource settings. There remains a notable gap in literature addressing tailored intraoperative assessment protocols for resource-constrained environments.Conclusions: In the absence of advanced intraoperative imaging, reliance on fundamental principles-such as thorough preoperative planning, direct visual and tactile assessment, and structured surgical technique-remains essential. There is an urgent need for context-specific research and pragmatic innovations to improve intraoperative fracture assessment and surgical outcomes in low-resource settings.","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 363","pages":"46-48"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144950751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

POSTTRAUMATIC SUBUNGUAL ACRAL NODULAR MELANOMA WITH BONE INFILTRATION TREATED VIA AMPUTATION OF THE DISTAL AND MIDDLE PHALANX: DESCRIPTION OF A CASE AND UPDATE ON THE TOPIC. 创伤后跖下肢端结节性黑色素瘤伴骨浸润，通过截肢远端和中端指骨治疗：一个病例的描述和该主题的最新进展。

Georgian medical news Pub Date : 2025-06-01

G Tchernev, V Broshtilova, KG Jr Tchernev, D S Krastev, N S Krastev, S Kordeva

{"title":"POSTTRAUMATIC SUBUNGUAL ACRAL NODULAR MELANOMA WITH BONE INFILTRATION TREATED VIA AMPUTATION OF THE DISTAL AND MIDDLE PHALANX: DESCRIPTION OF A CASE AND UPDATE ON THE TOPIC.","authors":"G Tchernev, V Broshtilova, KG Jr Tchernev, D S Krastev, N S Krastev, S Kordeva","doi":"","DOIUrl":"","url":null,"abstract":"Acral lentiginous melanoma (ALM) is a rare type of cutaneous malignant melanoma, predominantly affecting the acral sites and subungual regions of the upper and lower extremities. Unlike other melanoma types, UV exposure is not considered as significant etiological factor. Instead, mechanical stress, particularly traumatic injury, is recognized as a potential contributor to ALM development, especially in weight-bearing areas such as the sole. The presence of pre-existing pigmented lesions may serve as precursors. While diagnostic and therapeutic approaches for skin cancer are well-established in existing guidelines - such as those proposed by the European Joint Committee (EJC) and the American Joint Committee on Cancer (AJCC) - certain limitations are evident. These standardized protocols may not be fully beneficial for each patient, which highlights the need for a more personalized, patient-focused approach. In response, alternative methodologies, including the personalized One Step Melanoma Surgery (OSMS), have been introduced. OSMS offers a single-stage surgical intervention that minimizes both financial and psychological burdens compared to the conventional two-step approach protocol by the EJC and AJCC guidelines. We present a 57-year-old woman with a tumor-like lesion on the right hallux. A prior injury 30-years earlier was reported, after which a pigmented lesion developed and remains stable for decades. Following a recent domestic trauma, the lesion underwent rapid malignant transformation into an aggressive subungual acral nodular melanoma with subsequent bone infiltration, staged IIC T4bN0M0, Clark level IIC, Breslow thickness >4mm. Amputation of the right distal and proximal phalanx of digitus I (hallux) was performed. BRAF testing, re-excision with a 1.7 cm margin with a sentinel lymph node biopsy within 2-4 weeks, and initiation of immunotherapy or targeted therapy, were recommended.","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 363","pages":"125-130"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144950758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

THE IMPORTANCE OF PROMOTING BREASTFEEDING-MATERNAL NUTRITION DURING LACTATION. 促进母乳喂养的重要性——哺乳期间母亲的营养。

Georgian medical news Pub Date : 2025-06-01

N Totadze

引用次数: 0

GENETIC ASPECTS OF WARFARIN DOSING ALGORITHMS IN CARDIAC SURGERY PATIENTS WHO HAVE UNDERGONE HEART SURGERY: SYSTEMATIC REVIEW. 接受心脏手术的心脏手术患者华法林给药算法的遗传方面：系统综述。

Georgian medical news Pub Date : 2025-06-01

G Svyatova, G Berezina, A Murtazaliyeva, Y Miyerbekov, U Imammyrzayev

{"title":"GENETIC ASPECTS OF WARFARIN DOSING ALGORITHMS IN CARDIAC SURGERY PATIENTS WHO HAVE UNDERGONE HEART SURGERY: SYSTEMATIC REVIEW.","authors":"G Svyatova, G Berezina, A Murtazaliyeva, Y Miyerbekov, U Imammyrzayev","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To evaluate the clinical outcome, safety, and application of personalized therapy using pharmacogenetic warfarin dosing algorithms in cardiac surgery patients systemically.Methods: This systematic review focused on 17 published studies between January 2015 to March 2025 regarding warfarin dosing algorithms incorporating CYP2C9 and VKORC1 polymorphisms in patients who underwent cardiac surgery. The primary outcomes were TTR, BER, and INR stability. The databases search was performed on Scopus, Web of Science, PubMed, and Cochrane.Results: This systematic review highlights the effectiveness of genotype-stratified warfarin dosing after cardiac surgery. Bayesian models showed an improvement in TTR, with NextDose achieving 63% versus 56% with standard dosing. Genotype-guided approaches reduced bleeding events from 34 to 16 and increased INR stability from 83.1% to 86.1%, improving dosing precision and achieving a TTR of 77.76% compared to 57.43%.Conclusion: These findings reinforce the clinical importance of the use of genotype data for more precise warfarin dosing in improving TTR, INR control, and bleeding risk. Further studies are needed to optimize the algorithms, extend the gene panels, and tailor the approaches more for patients after cardiac surgery.","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 363","pages":"89-104"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144950542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CORRELATION OF FETAL MEASUREMENTS WITH GESTATIONAL AGE IN 144 ABORTED FETUSES: A CROSS-SECTIONAL HOSPITAL-BASED OBSERVATIONAL STUDY. 144例流产胎儿胎儿测量与胎龄的相关性：一项基于医院的横断面观察性研究。

Georgian medical news Pub Date : 2025-06-01

Z Alkhafaje, A Kmkm, R Madhloom, N Abdulkhaleq, D Farhan, S Ali, H Al-Hussaniy, A Harfash, A Rashid, U Altimari

{"title":"CORRELATION OF FETAL MEASUREMENTS WITH GESTATIONAL AGE IN 144 ABORTED FETUSES: A CROSS-SECTIONAL HOSPITAL-BASED OBSERVATIONAL STUDY.","authors":"Z Alkhafaje, A Kmkm, R Madhloom, N Abdulkhaleq, D Farhan, S Ali, H Al-Hussaniy, A Harfash, A Rashid, U Altimari","doi":"","DOIUrl":"","url":null,"abstract":"Background: Determination of correct gestational age is fundamental to obstetric care and is important during an autopsy as well as for clinical assessment of the growth of the fetus. Various fetal parameters like fetal anthropometry are used for the calculation of Gestational Age (The present study aimed to study the correlation between fetal anthropometric measurements like Crown-Rump length, Femur length, Head Circumference (HC), Bi-Parietal diameter (BPD) and Abdominal Circumference (AC) and Gestational age to derive regression equations for the same.Methods: This cross-sectional hospital-based observational study was conducted at Alkharama Hospital, Baghdad; TS involved 144 aborted fetuses without congenital anomalies, aged between 12 to 40 weeks of gestational age. As per the standard protocol, the fetal measurements were documented. Regression equations are derived for the anthropometric measurements.Results: In the present study, the correlation coefficients of the equation are 0.937, 0.984, 0.982, 0.987, 0.991, and 0.992, respectively, for birth weight, HC, CRL, BPD, FL, and AC. Gestation has a robust positive association with all other indices, with correlation coefficients ranging from 0.94 to 0.99, all of which are statistically significant at p<0.001.Conclusion: All fetal measures exhibit a positive correlation with gestational age. FL (R=0.991) and AC (R=0.992) exhibit the highest correlations with GA.","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 363","pages":"118-124"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144950808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0