Georgian medical news最新文献

{"title":"NICOLAU SYNDROME: CUTANEOUS NECROSIS FOLLOWING DICLOFENAC INTRAMUSCULAR INJECTION.","authors":"N Bhuyyar, B Khombare, A Panicker, Sh Teli, M Shalavadi, K Choudhari","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Nicolau syndrome, although it is quite rare, often occurs following Intramuscular injections of different medications, especially diclofenac and pencillin's. Accordingly, its symptoms usually begin with severe pain during injection, leading to ulceration and necrosis of the local tissue over time. Immediate diagnosis and treatment in the case of the syndrome are of great Importance. Diclofenac is class of NSAID's act as anti-inflammatory drug through inhibiting the Cycloxygenase-I and Cycloxygenase-II (COX-I AND COX-II) enzymes.</p><p><strong>Case report: </strong>In our case report we report the case of a 23-year-old female who developed the Nicolau Syndrome after an intramuscular injection in her left gluteal region of single dose diclofenac sodium to treat a headache, body ache, and chills. A physical examination revealed skin necrosis with the size of approximately 5×5cm. The patient was managed by administering intravenous antibiotics and analgesics, followed by surgical debridement, leading to satisfactory wound healing.</p><p><strong>Conclusion: </strong>This case highlights the importance of recognizing early warning signs of NS and adopting safe injection practices to prevent this serious adverse effect. Clinicians should be aware of the potential risks associated with intramuscular injections and take steps to minimize them.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 361","pages":"127-128"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144689966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE PHENOMENOLOGY OF EARLY DEVELOPMENTAL DISORDERS AS A FORMATIVE FACTOR IN THE DEVELOPMENT OF ADDICTIVE BEHAVIOUR IN THE MODERN CONDITIONS OF UKRAINIAN SOCIETY.","authors":"S Lobanov","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Children with early developmental disorders are at greater risk for developing addictive behaviors because of their emotional, cognitive, and social disabilities. This study analyzes Ukrainian people with early social isolation, stress, dysfunctional families, digital addiction, and lack of support to determine how these factors combine to increase the chances of addiction.</p><p><strong>Methods: </strong>This research is based on phenomenological qualitative methodology. The participants included 20 adult Ukrainians aged 19-45 diagnosed with ADHD, ASD, or learning disabilities. Participants were recruited using purposive sampling. The analysis was conducted using NVivo 14 and RStudio software.</p><p><strong>Results: </strong>The results identified that participants aged between 19-45 years and suffering from developmental disorders, with a nearly equal gender ratio (11 males, 9 females) and different occupational, educational, and family backgrounds, resulted in five prominent themes during the qualitative analysis. The themes include Early Social Isolation, Coping with Stress, the Influence of the Family Environment, the Role of Digital Addiction, and the Lack of Support Systems. Each theme showed different pathways that led to addiction, such as peer rejection, work/school pressure, dysfunctional families, digital overdependence, and lack of support and treatment. These themes were strengthened through focus group discussions with parents, caretakers, mental health professionals, and teachers, which called for integrated solutions.</p><p><strong>Conclusions: </strong>The study emphasizes socio-environmental stressors that build on early developmental changes as a primary reason for addiction.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 361","pages":"155-163"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144689891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MEDICAL TOURISM AS A DRIVER OF UKRAINE'S ECONOMIC RECOVERY: PRE-WAR EXPERIENCE AND STRATEGIC GUIDELINES FOR THE POST-WAR PERIOD.","authors":"V Teremetskyi, D Astafiev, S Mosondz, M Pakhnin, O Bodnar-Petrovska, R Igonin, S Lifyrenko","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Aim: </strong>The purpose of the article is to study the dynamics of medical tourism development in Ukraine in recent years before the full-scale invasion of the Russian Federation, and also to identify the main directions of its recovery in the post-war period.</p><p><strong>Materials and methods: </strong>The study is based on an interdisciplinary approach that combines legal analysis, economic modeling, and elements of sustainable urban development research. The methodological framework includes systemic-structural and functional-legal analysis of Ukrainian legislation on healthcare, investment policy, and regional development, as well as empirical data on the state of medical tourism in the pre-war period. Analytical methods were used to identify relationships between the development of medical tourism and the resilience of urban environments under crisis conditions.</p><p><strong>Results: </strong>The article analyses examples of successful implementation of public-private initiatives, in particular, the creation of Dnipro Medical Cluster. Particular attention is paid to the consideration of medical tourism as a factor in the formation of economic and legal resilience of Ukrainian cities. It is substantiated that the development of medical tourism has contributed to increasing the resilience of the urban environment to external crises. The article considers new challenges - ensuring access to medical services for internally displaced persons, organisation of rehabilitation of victims, emergence of the phenomenon of forced medical tourism.</p><p><strong>Conclusions: </strong>The strategic guidelines for the development of medical tourism in the post-war period are proposed. It is concluded that the restoration and development of medical tourism in Ukraine has a double meaning - as an economic tool and as a means of ensuring the sustainability of urban systems in the period of post-war transformation. Implementation of the proposed measures will contribute not only to economic growth, but also to strengthening the resilience of Ukrainian cities as centres of medical, social and investment opportunities.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 361","pages":"94-103"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144689965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ABO BLOOD GROUPS IN RELATION TO ANXIETY, STRESS AND DEPRESSION.","authors":"A Al-Saraj, S Al-Ashou","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>People have been suffering from affective illnesses including anxiety, stress, and depression as a result of the lifestyle changes that have occurred in our cultures. Research indicates a connection between specific blood types and several medical or mental illnesses. Stress, anxiety, and depression are common events in life and are more noticeable among college students. The objective of the study is to estimate the relationship of blood groups with stress, anxiety and depression among university students.</p><p><strong>Methods: </strong>This is a cross-sectional study, carried out via a web-based online survey, using the DASS-21 questionnaire, pharmacy college students' levels of stress, anxiety, and depression were measured. With a sterile lancet, blood samples were drawn from each participant via finger prick. Participants' ABO blood group phenotype was identified using the slide agglutination method using anti-A, anti-B, and anti-D monoclonal blood group reagents.</p><p><strong>Results: </strong>This study shows that 46.2%, 62.5%, and 62.5% of the second-year students of the pharmacy college suffer from stress, anxiety and depression ranging from mild to extremely severe levels. Among the participants, the AB blood group subjects showed the highest prevalence of stress (54.5%), the blood group A had the highest prevalence of anxiety (67.3%), and blood group B demonstrated the highest prevalence of depression (71.4%).</p><p><strong>Conclusion: </strong>According to this study, there is a high prevalence of stress, anxiety and depression among pharmacy college students. However, there is no statistically significant association between the incidence of these problems and the ABO blood group.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 361","pages":"73-79"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144689945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE INCIDENCE OF RESISTANCE TO ANTI-TUBERCULOSIS DRUGS AMONG DIFFERENT CATEGORIES OF TUBERCULOSIS PATIENTS IN THE REPUBLIC OF AZERBAIJAN.","authors":"J Aliyev","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In recent years, the epidemiological situation of tuberculosis in the world has remained tense. One of the main reasons for the epidemiological tension is the rapid increase in resistance to anti-tuberculosis drugs. The status and frequency of resistance among different categories of tuberculosis patients in the Republic of Azerbaijan have been investigated. In the last three years (2021-2023), sputum and other examination materials of 11,093 tuberculosis patients in our country were sent to the \"National Reference\" laboratory for susceptibility testing. 40.7% of those examined are initially registered, and 59,3% are recurrent patients. Resistance to various types of drugs was detected in 20,4% of initially registered patients and 31,2% of repetitive ones. Among the examined patients, the highest frequency of Mono-H and Poly-resistance (HS, HE, HSE) was found in those who did not previously applied to anti-tuberculosis institutions - 66,9%, in initially registered patients - 38,9%, in relapses - 36,7%, in those who violated the treatment regimen - 25,1%, and the least in patients after unsuccessful treatment - 15,0%. Mono, Poly-resistance (R, RS, RE, RSE) was found in 36,9% of those who violated the treatment regimen, 36.4% after unsuccessful treatment, 35.2% in relapses, 27,8% in initially registered patients, and 10,7% among those who had not previously registered. The level of MDR was higher among those who failed treatment and violated the treatment regimen. Thus, they are 32,0% and 24,9%, respectively. The incidence of GDD forms, 16,5%, was observed most often among patients with unsuccessful treatment. One of the main reasons for the epidemiological tension is the high prevalence of broad-spectrum drug resistance among persistent forms (49,2%). The increase in resistance among relapsers and treatment defaulters (20,1% and 19,9%, respectively) is one of the main reasons for the low treatment effectiveness.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 361","pages":"190-193"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144689890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DIFFERENTIATED THERAPY OF PATIENTS WITH INTRACEREBRAL COMPLICATED HEMISPHERIC ISCHEMIC CEREBRAL STROKE WITH SECONDARY BRAINSTEM HEMORRHAGES AGAINST THE BACKGROUND OF HYPERTENSIVE ENCEPHALOPATHY.","authors":"V Dariy, M Sikorska, I Vizir, D Khramtsov, K Serikov","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The purpose of the study is to assessment of the risk of secondary brainstem hemorrhages against the background of hypertensive encephalopathy in patients with intracerebral complicated hemispheric ischemic cerebral stroke using anticoagulant therapy. Was conducted a clinical and pathological study of 97 patients with intracerebral complicated hemispheric ischemic cerebral stroke aged 41 to 87 years. Of these, 55 were men (56,7%), average age 72,5±2,4; women 42 (43,3%), average age 76,5±2,1. Data on survival time and complications in the form of secondary brainstem hemorrhages directly correlated with the results of pathological changes in the brainstem. During autopsy of deceased patients with hemispheric ischemic cerebral stroke complicated by secondary hemorrhages of the brainstem who received anticoagulant therapy, in 12 cases (70,6%) out of 17, secondary massive hemorrhages in the brainstem were found, consisting of multiple hemorrhagic foci merging with each other. In individuals with hemispheric ischemic cerebral stroke who did not receive anticoagulant therapy, pathomorphologically, secondary massive hemorrhages in the brainstem were noted in only 12 (25,5%) of 47 deceased, while in 35 observations (74,5%), hemorrhages were determined in the form of individual hemorrhagic foci of small size or individual small-point hemorrhages, sometimes detected during macroscopic examination. Data on the presence of hypertensive encephalopathy in the pre-stroke anamnesis directly correlated with the results of secondary pathological changes in the brainstem. At autopsy, hypertensive encephalopathy was detected in 92,2% of deceased patients with secondary hemorrhages in the brainstem, while with ischemic nature of brainstem changes only in 42,4%. The above proves the need to take into account differentiated therapy depending not only on the nature of the damage to the hemispheric structures, but also on the pathomorphological type of secondary changes in the brainstem. In patients with hemispheric ischemic infarction who are predisposed to complicated hemorrhagic secondary brainstem syndrome, especially those with a history of hypertensive encephalopathy, the use of anticoagulant, thrombolytic, and dual antiplatelet therapy is not recommended due to the risk of developing secondary hemorrhagic stem syndrome as a consequence of secondary changes in microvessels, which always change under the influence of high blood pressure.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 361","pages":"6-10"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144689950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PILOT STUDY ON THE CARDIOVASCULAR MORBIDITY IN OLDER PEOPLE IN THE REGION OF BURGAS IN BULGARIA.","authors":"D Gospodinov, S Pishev, B Parashkevova, N Gerasimov, G Petrova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Cardiovascular morbidity is a leading cause of complaints in the older population.</p><p><strong>Objectives: </strong>The goal of this study is to present the results of a basic assessment of present cardiovascular diseases (CVD) in older people in the region of Burgas in Bulgaria.</p><p><strong>Methods: </strong>A six-month cross-sectional study was conducted in the municipality of Burgas. People aged 65 and older were interviewed at pensioners' clubs by a team of 4 physicians including cardiologists, and a pulmonologist. Clinical parameters were also measured.</p><p><strong>Results: </strong>A total 647 people participated in the study with a prevalent female cohort (84%). The average age was approximately 73 years. 426 (66%) of the people reported diagnosed diseases from 1 to 5 (1.7 on average per person). Blood pressure was elevated than the normal values of 140/90 mmHg with higher levels observed in the male group. All participants had glucose levels higher than the physiological norm of 5.6mmol/l. Total cholesterol in the male cohort was below the recommended values of 5.2mmol/l, while in the female cohort levels were higher (5.59mmol/l). HDL and LDL were found to be close to the values recommended for people without CVDs, and 85% reported hypertension.</p><p><strong>Conclusions: </strong>Hypertension is the most prevalent cardiovascular condition among the older population in Burgas. Almost all older individuals have comorbidities.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 361","pages":"142-147"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144689972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PROTECTIVE EFFECTS OF CURCUMA LONGA IN A ROTENONE-INDUCED RAT MODEL OF PARKINSON'S DISEASE: ELECTROPHYSIOLOGICAL AND BEHAVIORAL EVIDENCE.","authors":"L Manukyan, L Darbinyan, K Simonyan, V Sargsyan, L Hambardzumyan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Parkinson's disease (PD) is characterized by progressive dopaminergic neurodegeneration leading to motor deficits, yet effective neuroprotective therapies remain limited. Curcuma longa (turmeric), a traditionally cultivated spice in Southeast Asia, exhibits potent antioxidant properties that may counteract neurodegenerative processes. This study investigated the neuroprotective potential of orally administered turmeric extract (1100 mg/kg) in a rotenone-induced rat model of PD. Rats received rotenone (2.5 mg/kg) for 21 days to induce PD-like pathology, followed by concurrent turmeric treatment. Neuroprotective outcomes were assessed using in vivo electrophysiology and the Cylinder test to evaluate motor function and forelimb use asymmetry. Turmeric extract administration significantly prevented rotenone-induced degenerative changes and motor impairments, indicating preservation of neuronal integrity and function. These findings suggest that turmeric extract mitigates rotenone-induced neurotoxicity, supporting its potential as a therapeutic agent for PD. Further studies are warranted to elucidate the underlying molecular mechanisms and optimize dosing strategies.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 361","pages":"178-184"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144689973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE IMPACT OF EPILEPTIC FOCUS LATERALIZATION ON THE STRUCTURE OF DEPRESSIVE SYMPTOMATOLOGY IN FOCAL EPILEPSY.","authors":"A Velilyaeva, T Turayev, A Djurabekova, M Umarova, F Khalimova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Focal epilepsy commonly involves affective disturbances that compromise treatment adherence and exacerbate seizure frequency.</p><p><strong>Aim: </strong>To assess the impact of epileptic-focus lateralization on the severity of depressive symptoms in patients with focal epilepsy.</p><p><strong>Materials and methods: </strong>Sixty patients (30 left-hemisphere, 30 right-hemisphere) were evaluated with the Hamilton Depression Rating Scale (HAM-D), State-Trait Anxiety Inventory (STAI), Patient Health Questionnaire-15 (PHQ-15), Emotional Reactivity Index (ERI), a depression-awareness scale, and speech productivity measures. Data were analyzed using the Shapiro-Wilk test for normality, Student's t-test, and Mann-Whitney U-test (p<0.05).</p><p><strong>Results: </strong>Left-hemispheric group: Predominance of apathy, anhedonia, and heightened self-reflection; mean HAM-D 7.5±1.2, with 76.6% meeting the threshold for clinically significant depression (HAM-D≥8). Right-hemispheric group: Predominance of anxiety (STAI 9.0±1.0), somatiform complaints (PHQ-15 7.0±1.5), and emotional lability (ERI 8.0±1.2); 83.3% exhibited high anxiety, and 71% significant somatization (PHQ-15≥10). Speech productivity was markedly reduced (2.0±1.1), with monotony and low spontaneity.</p><p><strong>Conclusions: </strong>Epileptic-focus lateralization shapes affective disturbance profiles and should guide personalized psychopharmacological and psychotherapeutic strategies in focal epilepsy.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 361","pages":"67-72"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144689889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ASSESSMENT OF PEDIATRIC INTERNS' COMMITMENT TO PNEUMOCOCCAL VACCINATION: A CROSS-SECTIONAL STUDY IN MEDICAL UNIVERSITIES OF ALMATY, KAZAKHSTAN.","authors":"D Saussanova, M Baymuratova, A Amirzhanova, K Uspanova, T Slyambayev, Z Tobylbayeva, A Izbassarova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>According to the World Health Organization, pneumococcal infection (PI) is one of the leading causes of morbidity and mortality among children under the age of five worldwide, particularly in developing countries.</p><p><strong>Objective: </strong>To assess the awareness, attitudes, and adherence of pediatric interns toward pneumococcal vaccination. The study also aimed to identify specific knowledge gaps regarding vaccine characteristics, immunization schedules, and factors contributing to antibiotic resistance, in order to justify the need for improvements in immunoprophylaxis education within medical universities.</p><p><strong>Materials and methods: </strong>A total population cross-sectional sociological study was conducted among 6th- and 7th-year pediatric faculty interns from two medical universities in Almaty, Kazakhstan (n=50).</p><p><strong>Results and discussion: </strong>The findings revealed that most interns do not feel fully prepared to independently conduct pneumococcal vaccination, despite a high level of awareness regarding its importance. These results highlight the urgent need to implement targeted educational programs aimed at deepening future pediatricians' knowledge in the prevention of pneumococcal infections.</p><p><strong>Conclusion: </strong>The data obtained suggest the necessity of strengthening educational curricula in medical universities, focusing on in-depth study of immunoprophylaxis, clinical microbiology, and antibiotic therapy.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 361","pages":"59-66"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144689947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}