Georgian medical news最新文献

{"title":"PSYCHOLOGICAL FEATURES OF THE REHABILITATION OF PERSONS WITH UROLITHIASIS.","authors":"S Kolupayev, M Goloborodko, S Bytiak, A Lavrinenko, M Lupyr, I Lantukh, I Lytvynova, O Gulbs, S Dikhtyarenko, O Kobets","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Urolithiasis, a common and painful condition, is influenced by various risk factors and can be mitigated through preventive measures and can be a painful condition associated with significant individual and health care burdens. For many, urolithiasis is a chronic disease, and chronic diseases are known to have a significant impact on the quality of life of the sufferers with development anxiety and depression. The goal of research was study of depression and anxiety level to develop and test a complex of psychological interventions in the system of psychosocial assistance of patients with urolithiasis.</p><p><strong>Material and methods: </strong>The study included 134 patients (men - 74, women - 60) with non-obstructive stones of the renal pelvis who obtained prescription for uteroscopic lithotripsy or percutaneous nephrolithotripsy and psychological help was suggested. All patients were referred by complex team of specialists with including urologist and psychologists; such methodology was used as clinical and anamnestic method; to assess the presence of depression in patients, the Montgomery-Asberg Depression Rating Scale (MADRS) and GAD-7 scale were used.</p><p><strong>Results: </strong>The signs of depression, psychoemotional disorders and of social maladaptation were evenly estimated in patients with urolithiasis as refusal to communicate, the reaction of \"denying the diagnosis\", irritability, increased aggressiveness, resigned from work immediately after the diagnosis. Signs of depression had tendency to increase before urological procedure and evenly reduced after performing in patients who refuse psychological assistance. The patients who receive psychological help are characterized by significant reducing signs of depression even before procedure. During the debriefing, the patients of that group were more actively interested in finding ways to solve both difficult everyday situations and problems related to the loss of health. Best psychological condition was established after performing procedure that could be explained escaping from expectation of possible complications in procedure. No one patient with severe level of depression was observed in one day after procedure. Similar picture was estimated and for anxiety dynamic. But absence of patients with high level of anxiety was found only for patients who obtained psychological assistance. Simultaneously there wasn't a close correlation between indicators of depression and anxiety (r=0.53).</p><p><strong>Conclusions: </strong>Majority of people who endured urolithiasis have initial mild level of depression (average MADRS about 24 points) and medium level of anxiety (average GAD-7 about 11.5 points). Psychological assistance could reduce it till 10.21±2.03 and 7.88±0.53 accordingly. The data obtained in the course of the work testify to the effectiveness of conducting a complex of psychotherapeutic interventions using cognitive training, cognitive-beh","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 359","pages":"40-44"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144007245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A CASE OF CECAL CANCER WITH RETROPERITONEAL ABSCESS.","authors":"Wang-Yong Li, Xiao-Yan Yang, Zhun Cai, Guo-Fu Chen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This paper reports a case of a 65-year old male patient with cecal cancer complicated by retroperitoneal abscess. The patient initially presented with abdominal pain and fever. Through a series of examinations such as laboratory tests, abdominal CT, and colonoscopy, a diagnosis was made. After abscess drainage and subsequent radical right hemicolectomy and abscess debridement, the patient received adjuvant chemotherapy. During the two-year follow-up, there was no recurrence. The paper also discusses the etiology, clinical manifestations, diagnosis, and treatment of colon cancer with retroperitoneal abscesses, aiming to improve clinicians' understanding and handling ability of this rare disease.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 359","pages":"45-48"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143983614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MEASLES IN PREGNANCY IN THE REPUBLIC OF KAZAKHSTAN: CLINICAL AND LABORATORY MANIFESTATIONS AND OUTCOMES.","authors":"B Kosherova, Sh Abbozova, M Smagul, G Zhumagaliyeva, T Sagyndykova","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>to study clinical and laboratory manifestations of measles in pregnant women, prognosis and outcomes of the disease in Kazakhstan (January 2023 - February 2024).</p><p><strong>Methods: </strong>334 medical records of women (20-43 years old) with confirmed diagnosis of measles (ELISA) were analyzed. General, biochemical blood tests and inflammatory markers were investigated.</p><p><strong>Results: </strong>- 20% of pregnant women were treated as inpatients and the rest as outpatients. - A spike in hospitalizations was recorded during winter months. - Low immunization: 48% of pregnant were unvaccinated and 52% had unknown vaccination status. - Complications included marked intoxication, bacterial infections and perinatal disorders (miscarriages, premature births, fetal deaths).</p><p><strong>Conclusions: </strong>Low vaccination rates and increased morbidity increase the risk of severe measles in pregnant women. Pre-pregnancy vaccination remains the only effective prevention method for mother and child.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 359","pages":"76-80"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MANIFESTATION OF RADIOPROTECTIVE PROPERTIES IN COPPER COMPLEXES [CU(LCF3)2] AND [СU(ADM)(PPH3)2]PF6.","authors":"A Karapetyan, C Santini, M Pellei, M Caviglia, A Dallakyan, Zh Petrosyan, M Danielyan, K Nebogova, V Grigoryan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>One of the first and direct signs of ionizing radiation's effect on a cell is chromosomes destabilization. By studying cytogenetic indices - including mitotic index, chromosomal aberrations, and the number of polyploid cells in the bone marrow cells of the femur, a significant difference was observed between intact and irradiated animals. This suggests that these indices can be considered as markers of irradiation by the technetium isotope. When assessing the survival rate, the highest survival value was recorded in the Group injected with [Сu(Adm)(PPh3)2]PF6. In terms of chromosomal aberrations and number of polyploid cells, irradiated animals showed reliable difference compared to the \"irradiation + [Cu(LCF3)2]\" group at both 15 and 30 days post-exposure, demonstrating the radioprotective property of the compound. Regarding the mitotic index, treatment with [Cu(LCF3)2] showed a trend toward normalization after 15 days, with a reliable difference between Groups 2 and 3 by the end of the study (after 30 days), further supporting the compound's beneficial effect. Analysis of survival, changes in cytogenetic parameters, and multivariate regression analysis when using both complexes confirms the highest efficiency of [Сu(Adm)(PPh3)2]PF6 compared to [Cu(LCF3)2]. Specifically, treatment with [Сu(Adm)(PPh3)2]PF6, in contrast to \"pure irradiation\", resulted in a significant difference across all parameters and led to the normalization of cytogenetic parameters from the early stages of observation. This suggests a pronounced radioprotective effect of the compound and an accelerated normalization of cytogenetic parameters.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 359","pages":"18-22"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144011529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CASE REPORT OF CAT SCRATCH DISEASE (BARTONELLA).","authors":"M Endeladze, M Zhamutashvili, T Gognadze, E Meskhi, N Jojua, M Akhvlediani","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We report a case of Cat Scratch Disease (CSD) in a 39-year-old male who presented to the emergency department of an infectious diseases center with high fever, chills, myalgia, arthralgia, sweating, dry cough, nausea, weakness, right axillary lymphadenopathy, and fatigue. Initial laboratory findings showed elevated inflammatory markers consistent with bacterial infection. Imaging revealed right axillary lymphadenopathy with multiple hypovascular lesions in the liver and spleen. Patient history revealed multiple cat bites over the past 5 years. Initial treatment with ceftriaxone and azithromycin was administered. Serology and histopathology confirmed Bartonella henselae infection. Despite initial clinical improvement and discharge with antibacterial therapy (macrolides and rifampicin for 14 days), the patient returned with recurrent symptoms due to medication non-adherence. His 16-year-old son also presented with similar lymphadenopathy. Both tested positive for Bartonella henselae. Surgical removal of enlarged lymph nodes and combined antibacterial treatment resulted in complete recovery, with follow-up imaging showing resolution of hepatosplenic lesions. This case highlights the familial transmission potential of CSD and the importance of medication adherence, accurate diagnosis, and timely treatment to prevent complications and recurrence.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 359","pages":"15-17"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"BIOCHEMICAL INSIGHTS AND HORMONAL MARKERS OF POLYCYSTIC OVARY SYNDROME IN SUDANESE WOMEN: EXPLORING INFERTILITY AND RISK FACTORS IN RED SEA STATE.","authors":"W Mohamed, R Eltayeb, H Osman, M Omer, E Ali, A Abdelmola, T Yousif, M Belhocine, S Taha, E Lfaki, W Alzahrani, A Babker, A Eltom, M Ismail, A Alfeel","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Polycystic Ovary Syndrome (PCOS) is a prevalent hormonal condition affecting women of reproductive age, with prevalence rates ranging from 5% to 13%. Symptoms include irregular menstrual cycles, androgen excess, hair growth, acne, and cysts in the ovaries, often seen during adolescence.</p><p><strong>Aim: </strong>The purpose of this study was to investigate the hormonal and biochemical profiles of women with PCOS in the Red Sea State, Sudan with a focus on infertility and associated risk factors.</p><p><strong>Materials and methods: </strong>This cross-sectional study involved 40 women with a Rotterdam-defined PCOS diagnosis and 40 healthy control subjects. Participants provided demographic information, including age, family history, irregular menstruation, infertility, metabolic abnormalities, and clinical symptoms. Serum was extracted to estimate hormonal profiles, and enzymatic techniques were used to analyze fasting blood glucose and lipid profiles, while ELISA quantitative methods were used for hormone profiles.</p><p><strong>Results: </strong>The study found that 40% of patients were aged 20-30, 45% were with primary schools' education level, 53% had low economic status, 58% had abnormal menstrual cycle features, 60% had a positive case history, 75% did not have chronic disease characteristics, 68% had infants, and 83% had normal body mass index. The study found an insignificant correlation between infertility hormones and lipid profiles in patients, with FSH, LH, and LDL showing insignificant variation, while PRL, Chol, TG, and HDL showed significant correlations.</p><p><strong>Conclusion: </strong>The study reveals significant changes in lipid and hormonal profiles in Sudanese women with PCOS, even those with normal BMI. Although cyst laterality doesn't strongly correlate with clinical indicators, more research is needed to understand its relationship with LH and chronic illness. Early screening and multidisciplinary therapy are crucial due to high incidence of dyslipidemia, positive family history, and irregular menstruation.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 359","pages":"32-39"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143968736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"BARRIERS AND SOLUTIONS IN THE USE OF ALTERNATIVE AND AUGMENTATIVE COMMUNICATION: A PILOT DESCRIPTIVE STUDY PRESENTING INSIGHTS FROM ARMENIAN PROFESSIONALS.","authors":"A Avagyan, T Ashekian, A Snkhchyan, H Mkrtchyan, T Petrosyan","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Individuals with severe disabilities often require Alternative and Augmentative Communication (AAC) systems to support their communication needs. However, the implementation of AAC is frequently hindered by a lack of awareness among professionals and insufficient prioritization within healthcare systems.</p><p><strong>Material and methods: </strong>The online survey method was used to collect data from the participating professionals for the report. We used the Tennessee Talks Virtual AAC Institute questionnaire.</p><p><strong>Results: </strong>This paper identifies three main factors contributing to the limited use of AAC: high rural populations and economic challenges leading to inadequate rehabilitation services, lack of prioritization of communication rehabilitation by healthcare management, and limited awareness of AAC's potential benefits. Additionally, professionals' prior experiences and motivations significantly influence the adoption of AAC systems.</p><p><strong>Conclusions: </strong>To enhance the effective use of AAC, it is essential to provide instruction aligned with the specific needs and cultural contexts of local communities, ideally facilitated by experienced professionals. By exploring the current AAC practices and barriers faced by professionals in Armenia, this study aimed to develop strategies and programs that promote the broader adoption and effectiveness of AAC systems in practice.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 359","pages":"63-71"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143968756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE ROLE OF LIVE BIRD MARKETS SHOULD BE EMPHASIZED IN PREVENTING THE SPREAD OF HIGHLY PATHOGENIC AVIAN INFLUENZA INFECTIONS.","authors":"T Hayashi, K Acharya, S Phuyal, I Konishi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Zoonotic diseases refer to infectious diseases caused by pathogens that infect or parasitize both humans and other vertebrate animals. In recent years, the novel coronavirus disease (COVID-19) has been known to be a zoonotic disease. Academic fields related to zoonotic diseases include veterinary medicine and virology. According to a report by the Food and Agriculture Organization of the United Nations (FAO), approximately 70% of new human infectious diseases identified since 1940 are of animal origin. On the other hand, approximately twice as many pathogens are transmitted from humans to animals as are transmitted from animals to humans. In other words, humans are a major source of infection for animals. Due to increased opportunities for various animals to be imported and kept as pets, pathogens that were previously rare or unknown can suddenly appear in human society. Alternatively, there are ethnic groups in the world who eat wild birds and animals that are not sufficiently cooked, and there have been cases of pathogens infecting wild birds and animals being transmitted to humans. If a zoonotic disease caused by a new pathogen like this becomes prevalent as an emerging infectious disease, there is a high risk of it becoming a pandemic because humans have not yet acquired immunity to the new pathogen. This problem was clearly evident in the Severe Acute Respiratory Syndrome (SARS) pandemic that emerged in 2003, and the COVID-19 pandemic caused by infection with SARS-CoV-2, which was identified in 2019. In this review, we discuss the importance of management practices and current information on zoonotic diseases in outlets selling live wild birds and wildlife for consumption.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 359","pages":"156-158"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144010210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CO-OCCURRENCE OF HANTAVIRUS PULMONARY SYNDROME AND HEMORRHAGIC FEVER WITH RENAL SYNDROME.","authors":"M Zhamutashvili, T Gognadze, N Jojua, E Meskhi, K Meskhi, E Dolmazashvili","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Hantavirus infections can manifest as two distinct clinical syndromes: Hantavirus Pulmonary Syndrome (HPS) and Hemorrhagic Fever with Renal Syndrome (HFRS). We present a rare case of a 36-year-old male patient who simultaneously developed both syndromes following exposure to Hantavirus. The patient presented with fever, headache, diarrhea, blurred vision, petechial rash, and oliguria. Laboratory findings revealed severe thrombocytopenia, leukocytosis with bandemia, elevated CRP, and increased creatinine levels. The patient subsequently developed pneumonia and acute kidney failure. Initially suspected as Crimean-Congo hemorrhagic fever due to endemic geographic considerations, the diagnosis of Hantavirus infection was confirmed by RT-PCR. This case highlights the importance of considering Hantavirus in the differential diagnosis of patients presenting with both pulmonary and renal manifestations, especially in endemic areas, and emphasizes the need for improved diagnostic techniques in developing countries.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 359","pages":"123-125"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FACTORS AFFECTING HEALTH RELATED QUALITY OF LIFE IN ADULT PATIENTS WITH BETA-THALASSEMIA MAJOR.","authors":"S Ahmed, A Brifkani, H Ali, N Allawi","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Health related quality of life (HRQoL) is a remarkable and powerful tool to decide the patient's perspective of their disease and its effect on their lives. Its application in thalassemia may have an impact on treatment option and may help predict mortality and morbidity.</p><p><strong>Method: </strong>This case control study included a total of 62 adult patients registered as β-thalassemia major at the Jin pediatric hematology-oncology center (Duhok city) in addition to 50 age and sex matched healthy controls. The RAND Short Form 36 (SF-36) Questionnaire was used to evaluate HR-QoL score, and data were analyzed using Statistical Package for Social Sciences software (SPSS).</p><p><strong>Result: </strong>The HRQoL mean scores were significantly lower in adults with thalassemia major when compared to their matched controls (66.35% Vs. 84.32% with P<0.0005). Among the eight domains of Short Form-36, all except role emotional were significantly reduced as compared to their respective scores in the controls. Among the patient's group, the most affected domain was the general health, while the least affected was the social function. Lower mean HRQoL scores were seen in those with female gender which was clinically significant only in the pain domain (p=0.004). Significantly lower scores were recorded for physical function, role limitation physical, energy/fatigue and general health domains in those with heart failure.</p><p><strong>Conclusion: </strong>The study documented that thalassemia major had lower HRQoL compared to their healthy counterparts. Further multicenter studies are needed to assess better the predictors of lower HRQoL in this population, since it would provide important insights for improving the management of the disease and the choices of the treatment.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 359","pages":"136-142"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143979223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}