Frontiers in Psychiatry最新文献

{"title":"Prevalence and associated factors of depression and posttraumatic stress disorder among trauma patients: multi-centered cross-sectional study.","authors":"Eden Alemayehu Gebresenbet, Samson Zegeye, Tolesa Diriba Biratu","doi":"10.3389/fpsyt.2025.1447232","DOIUrl":"10.3389/fpsyt.2025.1447232","url":null,"abstract":"<p><strong>Background: </strong>Stress-related disorders, such as post-traumatic stress disorder (PTSD), are expected to be the leading cause of global mortality and morbidity by 2030. However, there is limited information on the prevalence of depression and PTSD among trauma patients in Ethiopia. Our study was aimed at determining the prevalence of depression and PTSD and factors affecting it among trauma patients.</p><p><strong>Methods: </strong>A hospital-based, multi-centered, cross-sectional study was conducted among 621 patients who visited the trauma outpatient clinic from April to June 2023. The stratified random sampling technique was used to select participants. Data were collected using standardized and pretested structured questionnaires and face-to-face interviews. Post-traumatic stress disorder was measured by the posttraumatic stress disorder checklist for DSM-5 (PCL-5), and depression was assessed by the Patient Health Questionnaire (PHQ-9). Data were analyzed using STATA version 14.1. Bivariable and multivariable logistic regression models were used to examine the association between outcome and independent variables. P-values less than 0.05 were considered statistically significant.</p><p><strong>Results: </strong>In this study, 621 study participants were involved, with a response rate of 100%. More than half (55%) of the participants were male. The participants' median age was 32 years, and the interquartile range (IQR) ranged from 25 to 43 years. The prevalence of depression was 35.4% (95% CI: 31.65-39.2), and the prevalence of PTSD was 14.2% (95% CI: 11.4-16.9). In multivariable analysis, being female (AOR = 1.58, 95% CI: 1.05-2.35), having no formal education (AOR = 1.7, 95% CI: 1.01- 2.85), having a low income (AOR = 4.5, 95% CI: 1.93-10.70), and having poor social Support (AOR=2.04, 95% CI 1.34-3.10) and multiple traumatic events (AOR=7.2, 95% CI: 4.1-12.7) were significant predictors of depression. For post-traumatic stress disorder, being female (AOR=2.7, 95% CI 1.46-5.06), no formal education (AOR=2.61, 95% CI: 1.25-5.46), urban residency (AOR=2.11, 95% CI: 1.14-3.90), having depression (AOR=7.01, 95% CI: 3.65-13.46), and multiple traumatic events (AOR=8.08, 95% CI: 2.83-23.14) were the associated factors identified.</p><p><strong>Conclusion and recommendation: </strong>The study revealed high levels of depression and post- traumatic stress disorder among trauma patients. Targeted interventions addressing socio-demographic disparities, such as income and education levels, alongside psychosocial support, are imperative.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"16 ","pages":"1447232"},"PeriodicalIF":3.2,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925855/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The influence of negative events on adolescents' mobile phone addiction: the chain mediating role of personality traits and emotional regulation style.","authors":"Mingxin Ji, Yi Qi, Huixin Tu, Siyi Wu, Xingrui Wang","doi":"10.3389/fpsyt.2025.1530212","DOIUrl":"10.3389/fpsyt.2025.1530212","url":null,"abstract":"<p><strong>Introduction: </strong>Teenagers' excessive dependence on mobile phones has aroused widespread concern in society. However, the complex mechanisms underlying the relationship between negative events and adolescent mobile phone addiction have not been thoroughly studied. The study aims to delve into the specific relationship between negative events and adolescent mobile phone addiction, and further explore the mediating role of personality traits (neuroticism) and emotional regulation (expression inhibition) in this relationship.</p><p><strong>Methods: </strong>This article is based on an empirical study involving 1399 randomly selected survey questionnaires from ordinary higher education institutions in Jiangsu and Zhejiang regions of China. The Adolescent Life Events Scale is employed to assess the impact of negative events on adolescents. The College Student Mobile Phone Addiction Scale is utilized to explore adolescent mobile phone usage behavior and addiction tendencies. The Big Five Personality Questionnaire is used to analyze personality tendencies, while the Emotion Regulation Scale is used to evaluate the frequency of using emotion regulation strategies.</p><p><strong>Results: </strong>(1) A notable positive correlation exists between negative events and mobile phone addiction. (2) Neurotic personality and expression inhibition play a mediating role in the chain effect between negative events and mobile phone addiction.</p><p><strong>Discussion: </strong>This study enriches relevant research on adolescent mobile phone addiction and offers a guide for educators and parents to solve the issue of adolescent mobile phone addiction. Negative events are positively correlated with mobile phone addiction, and neurotic personality and expressive inhibition play a chain mediating role between them.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"16 ","pages":"1530212"},"PeriodicalIF":3.2,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11926157/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"No relation between fMRI findings and thought distortion in mood disorder? A claim for new studies.","authors":"Adriana Munhoz Carneiro, Pedro Henrique Rodrigues da Silva, Valquiria Aparecida da Silva, Andre Russowsky Brunoni","doi":"10.3389/fpsyt.2025.1435227","DOIUrl":"10.3389/fpsyt.2025.1435227","url":null,"abstract":"","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"16 ","pages":"1435227"},"PeriodicalIF":3.2,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11926741/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Initial evidence for neural correlates following a therapeutic intervention: altered resting state functional connectivity in the default mode network following attention training technique.","authors":"Torben Müller, Svenja Krug, Özlem Kayali, Erik Leichter, Niklas Jahn, Lotta Winter, Tillmann H C Krüger, Kai G Kahl, Christopher Sinke, Ivo Heitland","doi":"10.3389/fpsyt.2025.1479283","DOIUrl":"10.3389/fpsyt.2025.1479283","url":null,"abstract":"<p><strong>Introduction: </strong>The Attention Training Technique (ATT) is a psychotherapeutic intervention in Metacogntive Therapy (MCT) and aims at reducing maladaptive processes by strengthening attentional flexibility. ATT has demonstrated efficacy in treating depression on a clinical level. Here, we evaluated ATT at the neural level. We examined functional connectivity (FC) of the default mode network (DMN).</p><p><strong>Method: </strong>48 individuals diagnosed with Major Depressive Disorder (MDD) and 51 healthy controls (HC) participated in a resting-state (rs) <i>functional magnetic resonance imaging</i> (fMRI) experiment. The participants received either one week of ATT or a sham intervention. Rs-fMRI scans before and after treatment were compared using seed-to-voxel analysis.</p><p><strong>Results: </strong>The 2x2x2 analysis did not reach significance. Nevertheless, a resting-state connectivity effect was found on the basis of a posttest at the second measurement time point in MDD. After one week, MDD patients who had received ATT intervention presented lower functional connectivity between the left posterior cingulate cortex (PCC) and the bilateral middle frontal gyrus (MFG) as well as between the right PCC and the left MFG compared to the MDD patients in the sham group. In HC we observed higher rsFC in spatially close but not the same brain regions under the same experimental condition.</p><p><strong>Conclusion: </strong>We found a first hint of a change at the neural level on the basis of ATT. Whether the changes in rsFC found here indicate an improvement in the flexible shift of attentional focus due to ATT needs to be investigated in further research paradigms. Further experiments have to show whether this change in functional connectivity can be used as a specific outcome measure of ATT treatment.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"16 ","pages":"1479283"},"PeriodicalIF":3.2,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11922856/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unmasking the psychological impact of the early COVID-19 pandemic in young adults: results from a cross-sectional online survey.","authors":"Omar Shazley, Michelle Teresa Wiciak, Daphne Santhosh","doi":"10.3389/fpsyt.2025.1521395","DOIUrl":"10.3389/fpsyt.2025.1521395","url":null,"abstract":"<p><strong>Background: </strong>The COVID-19 pandemic emerged as an international public health emergency and threat to individual psychological resilience.</p><p><strong>Objective: </strong>To examine the prevalence of psychological issues and identify key associations with mental health indicators in young adults (ages 18-28) worldwide during the initial phase of the pandemic.</p><p><strong>Methods: </strong>Through a cross-sectional online survey utilizing convenience sampling, we collected data on demographics, COVID-19-related questions, depression (Patient Health Questionnaire-9), anxiety (Generalized Anxiety Disorder-7), stress/trauma (Impact of Event Scale-Revised), and fear of COVID-19 (Fear of COVID-19 scale) between September 2020-January 2021. A total of 183 were eligible analysis. All statistical analyses were set at alpha = 0.05.</p><p><strong>Results: </strong>Over 70% of participants reported mild anxiety (n=129), 80% mild depression (n=136), 40% pandemic-related trauma (n=61), and 50% high fear (n=88). Female respondents reported higher anxiety (t(173)=-3.352, <.001), depression (t(166)=-3.310, P=.001), and trauma from COVID-19 ((t(151)=-2.004, P=.047). Hispanic/Latino/a/x participants reported higher depression (F(2,156)=7.761, P<.001) and trauma scores (F(2,143)=3.999, P=.020). Age in 2020 was associated with trauma total scores (F(1,154)=4.230, P=0.041, R2 = 0.027). Individuals who were mandated a quarantine were linked to lower levels of anxiety (F(2,175)=3.442, P=.034) and depression (F(2,170)=3.092, P =.048) than those not mandated. Those quarantined with close contacts were linked to lower anxiety (t(162.184)=2.705, P =.008) and trauma (t(149)=2.169; P=.032). Close contacts' hospitalization from COVID-19 infections were linked to lower anxiety (t(127)=2.855, P=.005), depression(t(123)=3.111, P=.002), and trauma (t(152)=-1.975, P=.050).</p><p><strong>Conclusion: </strong>The findings highlight the significant effect COVID-19 had on mental health in young adults worldwide.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"16 ","pages":"1521395"},"PeriodicalIF":3.2,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11922939/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research on prediction model of adolescent suicide and self-injury behavior based on machine learning algorithm.","authors":"Yao Gan, Li Kuang, Xiao-Ming Xu, Ming Ai, Jing-Lan He, Wo Wang, Su Hong, Jian Mei Chen, Jun Cao, Qi Zhang","doi":"10.3389/fpsyt.2024.1521025","DOIUrl":"10.3389/fpsyt.2024.1521025","url":null,"abstract":"<p><strong>Objective: </strong>To explore the risk factors that affect adolescents' suicidal and self-injurious behaviors and to construct a prediction model for adolescents' suicidal and self-injurious behaviors based on machine learning algorithms.</p><p><strong>Methods: </strong>Stratified cluster sampling was used to select high school students in Chongqing, yielding 3,000 valid questionnaires. Based on whether students had engaged in suicide or self-injury, they were categorized into a suicide/self-injury group (n=78) and a non-suicide/self-injury group (n=2,922). Gender, age, insomnia, and mental illness data were compared between the two groups, and a logistic regression model was used to analyze independent risk factors for adolescent suicidal and self-injurious behavior. Six methods-multi-level perceptron, random forest, K-nearest neighbor, support vector machine, logistic regression, and extreme gradient boosting-were used to build predictive models. Various model indicators for suicidal and self-injurious behavior were compared across the six algorithms using a confusion matrix to identify the optimal model.</p><p><strong>Result: </strong>In the self-injury and suicide groups, the proportions of male adolescents, late adolescence, insomnia, and mental illness were significantly higher than in the non-suicide and self-injury groups (<i>p <</i>0.05). Compared with the non-suicidal self-injury group, this group also showed significantly increased scores in cognitive subscales, impulsivity, psychoticism, introversion-extroversion, neuroticism, interpersonal sensitivity, depression, anxiety, hostility, terror, and paranoia (p <0.05). These statistically significant variables were analyzed in a logistic regression model, revealing that gender, impulsivity, psychoticism, neuroticism, interpersonal sensitivity, depression, and paranoia are independent risk factors for adolescent suicide and self-injury. The logistic regression model achieved the highest sensitivity and specificity in predicting adolescent suicide and self-injury behavior (0.9948 and 0.9981, respectively). Performance of the random forest, multi-level perceptron, and extreme gradient models was acceptable, while the K-nearest neighbor algorithm and support vector machine performed poorly.</p><p><strong>Conclusion: </strong>The detection rate of suicidal and self-injurious behaviors is higher in women than in men. Adolescents displaying impulsiveness, psychoticism, neuroticism, interpersonal sensitivity, depression, and paranoia have a greater likelihood of engaging in such behaviors. The machine learning model for classifying and predicting adolescent suicide and self-injury risk effectively identifies these behaviors, enabling targeted interventions.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"15 ","pages":"1521025"},"PeriodicalIF":3.2,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11922950/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of cognitive function in bipolar disorder with passive smartphone keystroke metadata: a BiAffect digital phenotyping study.","authors":"Olusola Ajilore, John S Bark, Alexander P Demos, John Zulueta, Jonathan Stange, Jennifer Duffecy, Faraz Hussain, Scott A Langenecker, Peter Nelson, Kelly Ryan, Melvin G McInnis, Alex Leow","doi":"10.3389/fpsyt.2025.1430303","DOIUrl":"10.3389/fpsyt.2025.1430303","url":null,"abstract":"<p><strong>Background: </strong>Cognitive dysfunction in bipolar disorder persists in the euthymic state and has been shown to be associated with a number of negative sequelae including treatment resistance and increased risk of relapse. There has been recent attention on digital phenotyping and passive sensing through smart, connected devices to probe cognition in real-world settings. BiAffect is a custom-built smartphone keyboard that captures keystroke metadata ('how you type, not what you type'). In previous studies, our group has demonstrated that BiAffect-derived keystroke metadata is associated with cognitive domains like processing speed. For the present study, we hypothesized that typing metadata would be significantly associated with executive function and planning.</p><p><strong>Methods: </strong>18 participants with bipolar disorder and 12 healthy comparison participants from the Prechter Longitudinal Study of Bipolar Disorder at the University of Michigan were provided a mobile phone with a customized keyboard that passively collected keystroke metadata. Participants also completed a neuropsychological battery including the Tower of London task. Irregularities in typing and times to make a move on the Tower of London task were compared using sample and Shannon entropy, respectively.</p><p><strong>Results: </strong>Participants with bipolar disorder had significant increases in entropy in typing (<i>p</i> = .005, <i>d</i> = -1.28) and entropy of Tower of London move times (<i>p</i> = .029, <i>d</i> = -.84). Furthermore, typing entropy was significantly associated with irregularity in Tower of London moves in participants (<i>r</i> = .59, <i>p</i> = .006), as well as variability of clinician-rated depressive symptoms and self-rated impulsive actions and feelings.</p><p><strong>Conclusions: </strong>This pilot study demonstrates that passive, unobtrusive smartphone keystroke metadata can be used to probe cognitive function and dysfunction in bipolar disorder, revealing multi-scalar behavioral features accessible through digital assays.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"16 ","pages":"1430303"},"PeriodicalIF":3.2,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11922855/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of psychological factors on the final clinical outcomes of patients undergoing ankle arthrodesis and ankle replacement.","authors":"Hongze Wang, Shihang Cao, Geng Liu, Jun Lu, Junkui Xu","doi":"10.3389/fpsyt.2025.1550465","DOIUrl":"10.3389/fpsyt.2025.1550465","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;This study aims to analyze the impact of different surgical procedures on the prognosis and psychological state of patients with end-stage ankle arthritis (ESAA) by comparing two groups of patients with ESAA who have undergone total ankle replacement (TAR) and ankle arthrodesis (AA), and to investigate whether preoperative psychological status can alter the final clinical outcomes.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This study retrospectively collected data from 66 patients with ESAA who underwent AA surgery in the Foot and Ankle Surgery Department of Xi'an Honghui Hospital between 2016 and 2023. In July 2024, the final follow-up of patients was conducted via telephone or WeChat, with a follow-up duration of no less than 12 months. Before surgery and at the final follow-up, evaluations were conducted using the Chinese version of the Hospital Anxiety and Depression Scale (HADS), the Visual Analogue Scale (VAS) for pain (ranging from 0 to 100mm), and the American Orthopaedic Foot and Ankle Society (AOFAS) ankle and hindfoot score. The study compared differences in pain scores, functional scores, and psychological scores between patients in the TAR and AA groups before surgery and at the final follow-up. Additionally, patients who underwent TAR and AA were further subgrouped based on the severity of their preoperative psychological status, in order to analyze the impact of preoperative psychological conditions on surgical prognosis.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 66 patients with ESAA completed the follow-up. At the final follow-up, both the VAS and AOFAS scores in the TAR group and the AA group showed significant improvement compared to preoperative levels. Among them, the TAR group performed better in terms of AOFAS scores, but no significant difference was observed in VAS scores between the two groups. Additionally, there was no significant difference in HADS scores between the two groups at the final follow-up. Regardless of whether they belonged to the high-HADS group or the low-HADS group, patients showed significant improvement in clinical scores compared to preoperative levels. However, at the final follow-up, the clinical scores of the high-HADS group were significantly lower than those of the low-HADS group, and the incidence of complications in the high-HADS group was also higher.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;This study found that both TAR and AA significantly improved patients' psychology, pain, and functional activities. Both surgical methods demonstrated similar improvements in terms of final psychological status and pain relief. However, patients in the TAR group showed better ankle function and mobility. Patients with poorer preoperative psychological status had worse clinical outcomes and faced a higher risk of complications. The study indicates that both TAR and AA are effective treatment options for patients with ESAA, but poor preoperative psychological status is one of the important ","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"16 ","pages":"1550465"},"PeriodicalIF":3.2,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11922897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of comorbid alexithymia on cognitive impairment in chronic schizophrenia: a large-sample study on the Han Chinese population.","authors":"Yuanping Liao, Yunhui Zhong, Kan Yang, Xiang-Yang Zhang","doi":"10.3389/fpsyt.2025.1517540","DOIUrl":"10.3389/fpsyt.2025.1517540","url":null,"abstract":"<p><strong>Background: </strong>Alexithymia and cognitive dysfunction are common in patients with schizophrenia. However, only a few studies have investigated the cognitive performance of patients with schizophrenia and comorbid alexithymia. This study aimed to investigate the relationship between alexithymia and neurocognitive impairment in patients with schizophrenia.</p><p><strong>Methods: </strong>A total of 695 patients who met the DSM-IV diagnostic criteria for schizophrenia were included in this cross-sectional study (male/female = 464/231). Demographic and clinical data were collected using self-reported questionnaires. The severity of alexithymia was assessed using the Toronto Alexithymia Scale (TAS-20), cognitive function was assessed using the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) tool, and the severity of psychiatric symptoms was assessed using the Positive and Negative Syndrome Scale (PANSS).</p><p><strong>Results: </strong>The prevalence of comorbid alexithymia in patients with chronic schizophrenia was 31.40%, with a male preponderance. Patients with alexithymia had higher PANSS negative symptom subscale scores and PANSS total scores than those without alexithymia (<i>p</i> < 0.05 for all). In addition, patients with alexithymia had more severe deficits in immediate memory, delayed memory, and language and lower RBANS scores than those without alexithymia. Stepwise multivariate regression analysis showed that alexithymia was a risk factor for language deficits and indicated low total RBANS scores in patients with schizophrenia.</p><p><strong>Conclusion: </strong>This study suggests that patients with chronic schizophrenia with alexithymia have poorer cognitive function than those without alexithymia. Some demographic characteristics and alexithymia are risk factors for cognitive dysfunction in patients with chronic schizophrenia.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"16 ","pages":"1517540"},"PeriodicalIF":3.2,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11922828/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bullying and depression among adolescents in East Asia: a scoping review on prevalence rates, risk and protective factors.","authors":"Jennifer Sie Hee Kiing, Elizabeth Sarah Ragen, Mohamed Sufyan Bin Mohmed Sulaiman, Wei Sheng Goh, Norman Jun Hao Tan, Sok Hui Ng, Yang Luo, Miny Samuel, Doris Young, Victor Weng Keong Loh","doi":"10.3389/fpsyt.2025.1497866","DOIUrl":"10.3389/fpsyt.2025.1497866","url":null,"abstract":"<p><strong>Introduction: </strong>Bullying and victimization in adolescence is associated with mental health problems including depression. Depression in East Asian adolescents presents similarities and differences from that in Western adolescents. This review reports on the prevalence and psychosocial associations of bullying and depression in East Asian adolescents.</p><p><strong>Methods: </strong>Electronic databases (Medline, and Embase) were searched for English language articles on bullying and its associations for a span of 10 years (1st January 2013 to 19th January 2024). Searches were limited to studies conducted in East Asia involving adolescents 10-19 years of age.</p><p><strong>Results: </strong>Out of 1,231 articles initially identified, 65 full-text articles (consisting of 44 cross-sectional and 21 cohort studies) met the inclusion criteria and were included for qualitative synthesis & analysis. Prevalence rates of bullying ranged from 6.1% - 61.3% in traditional bullying victimization and 3.3% to 74.6% in cyberbullying victimization with higher rates in at-risk groups (e.g., adolescents with internet addiction). Psychosocial associations of bullying and depression which were similarly found in Western cultures include individual factors of coping style and gender; family factors of functioning and sibling relationships; and community factors of friendship and school-connectedness. In contrast, unique East Asian risk factors included being different (i.e., sexual minority status) and teachers as bullies.</p><p><strong>Conclusion: </strong>Findings of this scoping review suggest that strong relationships within families, peers and the school community coupled with adolescents' positive coping style are protective against the negative effects of bullying. Conversely, poor parent-child attachment in the midst of family dysfunction, poor engagement with peers and the school community together with low self-esteem predispose East Asian adolescents to depressive symptoms as a result of victimization. Similar to Western cultures, adolescents who are bully-victims and poly-victims are most vulnerable to depression. As a significant proportion of bullying occurred in school, future research could focus on a whole-school intervention approach to counter bullying.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"16 ","pages":"1497866"},"PeriodicalIF":3.2,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11932047/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143699644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}