Frontiers in Psychiatry最新文献

{"title":"Pituitary adenylyl cyclase-activating polypeptide modulates the stress response: the involvement of different brain areas and microglia.","authors":"Anika Singh, Paul Shim, Sadaf Naeem, Shafiqur Rahman, Kabirullah Lutfy","doi":"10.3389/fpsyt.2024.1495598","DOIUrl":"10.3389/fpsyt.2024.1495598","url":null,"abstract":"<p><p>Stress is necessary for survival. However, chronic unnecessary stress exposure leads to cardiovascular, gastrointestinal and neuropsychiatric disorders. Thus, understanding the mechanisms involved in the initiation and maintenance of the stress response is essential since it may reveal the underpinning pathophysiology of these disorders and may aid in the development of medication to treat stress-mediated diseases. Pituitary adenylyl cyclase activating polypeptide (PACAP) and its receptors (PAC1, VPAC1 and VPAC2) are expressed in the hypothalamus and other brain areas as well as in the adrenal gland. Previous research has shown that this peptide/receptor system serves as a modulator of the stress response. In addition to modulating the stress response, this system may also be connected to its emerging role as neuroprotective against hypoxia, ischemia, and neurodegeneration. This article aims to review the literature regarding the role of PACAP and its receptors in the stress response, the involvement of different brain regions and microglia in PACAP-mediated modulation of the stress response, and the long-term adaptation to stress recognizable clinically as survival with resilience while manifested in anxiety, depression and other neurobehavioral disorders.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"15 ","pages":"1495598"},"PeriodicalIF":3.2,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11807976/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143389974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maximising translational value of the Iowa gambling task in preclinical studies through the use of the rodent touchscreen.","authors":"Judith A Pratt, Brian J Morris","doi":"10.3389/fpsyt.2025.1518435","DOIUrl":"10.3389/fpsyt.2025.1518435","url":null,"abstract":"<p><p>The Iowa gambling task is widely employed to assess the evaluation of risk versus reward contingencies, and how the evaluations are implemented to gain advantageous returns. The cognitive processes involved can be compromised in psychiatric conditions, leading to the development of analogous tasks with translational value for use in rodents. The rodent touchscreen apparatus maximises the degree of similarity with the human task, and in this review we provide an outline of the use of rodent touchscreen gambling tasks in preclinical studies of psychiatric conditions. In particular, we describe how the basic task has been adapted to probe the relative contributions of different neurotransmitter systems, and specific aspects of cognition. We then offer a perspective on how the task might be employed most beneficially in future studies.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"16 ","pages":"1518435"},"PeriodicalIF":3.2,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11808010/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143390331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Attitudes towards persons with disabilities vs. personality traits of Polish students.","authors":"Iwona Radlińska, Marta Kożybska, Arkadiusz Prajzner, Łukasz Krzywoszański, Beata Karakiewicz","doi":"10.3389/fpsyt.2024.1477877","DOIUrl":"10.3389/fpsyt.2024.1477877","url":null,"abstract":"<p><strong>Objective: </strong>The study aimed to establish the relationship between attitudes towards persons with disabilities and personality traits among Polish students, and whether sociodemographic factors moderate this.</p><p><strong>Methods: </strong>A cross-sectional self-report online survey was conducted on 595 Polish students, aged 18-29, from different fields of study: 1) natural science and engineering technology; 2) social science and humanities; 3) medical and health sciences; 4) law, economics, and management. Polish adaptations of the scales were used in the study: Multidimensional Attitudes Scale Towards Persons With Disabilities (MAS) and the Ten Item Personality Inventory (TIPI).</p><p><strong>Results: </strong>A significant correlation was demonstrated between attitudes towards individuals with physical disabilities and a range of personality traits, including agreeableness, extroversion, conscientiousness, and openness, among Polish students. The strongest attitude predictors were openness to experience, agreeableness, and extraversion, with correlation coefficients ranging from -0.06 to -0.19, -0.14 to -0.22, and -0.09 to -0.15, respectively. As scores increased in these personality traits, attitudes towards people with disabilities became more positive. However, conscientiousness (-0.07 to -0.09) and emotional stability (-0.02 to 0.12) were poor predictors. The supplementary analyses indicate that contact with a person with a disability and socio-demographic factors, such as gender, age, place of residence, mode, and field of study, assessment of one's health, and material conditions, did not moderate the relationships between personality dimensions and attitudes towards persons with disability.</p><p><strong>Conclusion: </strong>Polish students' attitudes towards individuals with physical disabilities are associated with personality traits such as agreeableness, extraversion, conscientiousness, and openness. However, the strength of these relationships is relatively weak. This relationship is not moderated by contact with a person with a disability or sociodemographic factors. It seems that undertaking educational interventions to strengthen the indicated personality traits is particularly important. The results indicate the need for further research into factors that modulate attitudes towards persons with disabilities, including a theoretical deepening of the problem and cultural aspects.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"15 ","pages":"1477877"},"PeriodicalIF":3.2,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11808036/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143390825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Individual differences in training time in the rat gambling task are unrelated to subsequent decision-making strategies.","authors":"Frida A Lindberg, Christakis Kagios, Nikita Tjernström, Erika Roman","doi":"10.3389/fpsyt.2025.1490196","DOIUrl":"10.3389/fpsyt.2025.1490196","url":null,"abstract":"<p><strong>Introduction: </strong>Decision-making requires individuals to perceive probabilities and risks associated with different options. The Iowa gambling task (IGT) is a widely used instrument that assesses decision-making under uncertainty and risk by varying monetary reinforcer/loss contingencies. The rat gambling task (rGT), based on the IGT, is a preclinical test using varying number of palatable reinforcers as wins and different duration of timeouts as punishment, mimicking losses. The rGT requires extensive operant training prior to the free choice sessions. The aim of the present study was to investigate if task acquisition and number of training days affected subsequent individual differences in decision-making strategies in the rGT, and if behavioral profiles impacted on task learning.</p><p><strong>Method: </strong>Training time and performance of 70 male Lister Hooded rats from previously published studies were herein used to investigate whether learning time affected later decision-making strategies in the free choice rGT. Behavioral profiles generated from a subset of animals were used to study the impact of underlying behavior on learning time.</p><p><strong>Results: </strong>There were differences in training days between fast, intermediate and slow learners. However, time required to acquire the rGT did not affect subsequent decision-making strategies in the free choice rGT. Finally, learning time was independent of underlying behavioral profiles.</p><p><strong>Discussion: </strong>In conclusion, neither decision-making strategies in the rGT nor behavioral profiles were correlated or differed between animals with different learning speed. This suggests that the large variation in training time between animals is unrelated to subsequent decision-making strategies during free choice rGT. Such information is valuable for researchers using the rGT.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"16 ","pages":"1490196"},"PeriodicalIF":3.2,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11808017/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143390106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mobile phone addiction and negative emotions: an empirical study among adolescents in Jiangxi Province.","authors":"Jin Luo, Guanqing Cai, Xiaofang Zu, Qiming Huang, Qing Cao","doi":"10.3389/fpsyt.2025.1541605","DOIUrl":"10.3389/fpsyt.2025.1541605","url":null,"abstract":"<p><strong>Background: </strong>The relationship between mobile phone addiction and negative affect among adolescents is characterized by intricate interconnections. These factors have an impact on the emotional and psychological well-being of young people. While previous studies have provided preliminary insights into this relationship, further in-depth exploration and research is required to fully understand the complex mechanisms behind these relationships and to identify any group differences.</p><p><strong>Methods: </strong>This study collected questionnaire data from 493 adolescents aged 17-22 years old in Jiangxi Province. The data were analyzed using Pearson correlation analysis, restricted cubic spline (RCS), and structural equation modelling (SEM) with the aim of exploring the mechanisms and differences in the effects of mobile phone addiction on negative emotions of different youth groups.</p><p><strong>Results: </strong>The findings of the study indicated notable discrepancies in mobile phone addiction by gender and place of residence. Secondly, mobile phone addiction among adolescents positively drives negative emotions. The findings revealed that negative emotions triggered by mobile phone addiction were significantly higher among rural adolescents than urban adolescents; male adolescents exhibited higher levels than female adolescents in the same place of residence. Additionally, family factors, physical exercise and psychological resilience can directly or indirectly inhibit mobile phone addiction among adolescents. Finally, adolescents' psychological resilience can significantly alleviate the negative emotions associated with mobile phone addiction. Physical exercise and family factors can reduce the negative emotional impact of mobile phone addiction by increasing psychological resilience.</p><p><strong>Conclusions: </strong>This study employs the relationship between mobile phone addiction and negative emotions in adolescents, reveals the complex mechanisms and group differences behind these relationships, and provides a fresh perspective for understanding the impact of mobile phone addiction on adolescents' mental health, as well as a scientific basis for the development of effective interventions.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"16 ","pages":"1541605"},"PeriodicalIF":3.2,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11807983/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143390380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spirituality and mental health - investigating the association between spiritual attitudes and psychosomatic treatment outcomes.","authors":"Thilo Hinterberger, Nike Walter","doi":"10.3389/fpsyt.2024.1497630","DOIUrl":"10.3389/fpsyt.2024.1497630","url":null,"abstract":"<p><strong>Background: </strong>The relationship between spirituality and mental health has garnered attention, fostering overall well-being. Spirituality, posited as a protective factor, may enhance resilience and provide meaning, thus benefiting mental health. This study aims to identify spirituality-associated factors influencing clinical outcomes in psychosomatic inpatients and validate the Transpersonal Spirituality Inventory (TSI).</p><p><strong>Methods: </strong>The study involved 4952 psychosomatic inpatients completing the Transpersonales Vertrauen (TPV) and 7739 patients completing the TSI, with assessments conducted at admission and discharge. Additional instruments included the ISR for symptom rating and the LK-18 for life skills. Factor analysis and Spearman's rank correlation were used to evaluate the validity of TSI and the relationship between spirituality and clinical outcomes.</p><p><strong>Results: </strong>Factor analysis confirmed the TSI's two-factor structure: \"centered connectedness\" (F1) and \"transcendent orientation\" (F2), with satisfactory internal consistency (Cronbach's α = 0.824 for F1 and 0.644 for F2). Higher spirituality levels, particularly in transpersonal trust and centered connectedness, correlated with lower depression and psychosomatic symptoms (ISR). Although these correlations were generally weak, significant associations were found between spirituality and life competences, particularly in meaning, belief, and values (r = .595 for TPV and .598 for TSI F1).</p><p><strong>Conclusion: </strong>Despite correlations between psychosomatic health and spirituality as measured with TPV and TSI were rather small several spirituality items could be identified which seem to have a prominent connection to the diagnosis and development of psychosomatic health. Specific spiritual attitudes, such as access to inner stillness and connection to a greater whole, were linked to positive treatment responses and reduced symptom burden. These findings suggest potential benefits in incorporating spirituality into psychosomatic treatments, though its complex and multifaceted nature warrants further investigation.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"15 ","pages":"1497630"},"PeriodicalIF":3.2,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11808015/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143390182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case report: Non-linear evolution of oxytocin informs YBOCS changes post-DBS of the bed nucleus of the stria terminalis for treatment resistant OCD.","authors":"Jean-Baptiste Belge, Vincent Geenen, Anne L Salado, Bruno Kaschten, Didier Martin, Gabrielle Scantamburlo","doi":"10.3389/fpsyt.2024.1473797","DOIUrl":"10.3389/fpsyt.2024.1473797","url":null,"abstract":"<p><strong>Introduction: </strong>Obsessive-compulsive disorder (OCD) is a challenging neuropsychiatric condition with a subset of patients remaining refractory to conventional treatments. Deep brain stimulation (DBS) of the bed nucleus of the stria terminalis (BNST) has shown promise for severe, treatment-resistant OCD. This case report examines the relationship between plasma oxytocin levels and OCD symptom severity following BNST-DBS.</p><p><strong>Methods: </strong>A 36-year-old patient with long-standing, treatment-resistant OCD underwent stereotactic implantation of DBS electrodes at the BNST. Postoperative assessments included OCD symptom severity using the Yale-Brown Obsessive Compulsive Scale (YBOCS) and plasma oxytocin levels, measured at 12 time points over three years. Longitudinal and correlational analyses were performed using linear and polynomial regression models.</p><p><strong>Results: </strong>Non-linear trends in oxytocin levels were identified, with polynomial regression revealing a significant quadratic term, suggesting a parabolic trend. Strong positive correlations were found between changes in oxytocin levels and YBOCS total, obsession, and compulsion scores.</p><p><strong>Conclusion: </strong>The findings suggest a significant non-linear evolution of oxytocin levels and a positive correlation with OCD symptom changes following BNST-DBS. Oxytocin levels could serve as a biomarker for DBS efficacy if this finding is replicated in larger studies.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"15 ","pages":"1473797"},"PeriodicalIF":3.2,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11807955/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143390831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with the revolving door phenomenon in patients with schizophrenia: results from an acute psychiatric hospital in Romania.","authors":"Vlad Dionisie, Maria Gabriela Puiu, Mihnea Costin Manea, Emanuel Moisa, Ana Maria Dumitru, Leila Ibadula, Aliss Madalina Mares, Corina Ioana Varlam, Mirela Manea","doi":"10.3389/fpsyt.2024.1496750","DOIUrl":"10.3389/fpsyt.2024.1496750","url":null,"abstract":"<p><strong>Background: </strong>The revolving door phenomenon refers to patients with frequent hospital admissions and emerged after deinstitutionalization reforms have been implemented. Schizophrenia is a severe and debilitating mental disorder and has frequently been identified as one of the most prevalent disorders among revolving door patients. Therefore, this research aimed to identify socio-demographic and clinical factors associated with the revolving door phenomenon in patients with schizophrenia.</p><p><strong>Methods: </strong>We conducted an observational and retrospective cohort study and collected data from the medical records of individuals admitted to the largest psychiatric hospital in Romania during a 2-year period. Patients with three or more admissions during a 12-month period were identified as revolving door.</p><p><strong>Results: </strong>Of the total of 635 patients included in this study, 108 met the criteria for revolving door. Patients had a mean age of 44.55±12.83 years and most of them were single (81.7%) and receiving a disability pension (68.7%) and had an illness duration of more than 5 years (81.9%). Male gender (p=0.000), younger age (p<0.05), presence of psychiatric comorbidity (p<0.05), substance use disorder (p=0.000) and alcohol use disorder (p<0.01) were associated with the revolving door patients. A binary linear logistic regression revealed that male gender (OR=1.92, 95%CI:1.21-3.08), shorter hospitalization (OR=0.982, 95%CI:0.964-1.000), substance use disorder (OR=2.47, 95%CI:1.16-5.26), verbal (OR=1.44, 95%CI:1.05-1.98) and physical (OR=1.331, 95%CI:1.017-1.744) aggression were predictive factors for frequent use of inpatient services.</p><p><strong>Conclusions: </strong>The results may facilitate development of future reform policies aimed at reducing the revolving door phenomenon, including implementing transitional care interventions between hospital and community services.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"15 ","pages":"1496750"},"PeriodicalIF":3.2,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11802556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The challenge of a late diagnosis of Autism Spectrum Disorder: co-occurring trajectories and camouflage tendencies. a case report of a young Autistic female with Avoidant Restrictive Food Intake Disorder.","authors":"Sara Passarini, Silvia Guerrera, Maria Picilli, Elisa Fucà, Laura Casula, Deny Menghini, Sabine Pirchio, Valeria Zanna, Giovanni Valeri, Stefano Vicari","doi":"10.3389/fpsyt.2024.1447562","DOIUrl":"10.3389/fpsyt.2024.1447562","url":null,"abstract":"<p><strong>Introduction: </strong>Autistic individuals may show several psychiatric co-occurrences, including Feeding and Eating Disorders (FEDs). Avoidant and Restrictive Food Intake Disorder (ARFID) consists of avoidance or restriction in food intake, leading to significant weight loss, nutritional deficiencies, and marked interference with psychosocial functioning. Both Autism Spectrum Disorder (ASD) and ARFID are characterized by the two main features of cognitive rigidity and sensory sensitivity, which may complicate differential diagnosis. There is a notable lack of information on the manifestation of ASD-ARFID co-occurrence, as well as tailored assessment tools and practice, and therapeutic approaches.</p><p><strong>Case description: </strong>This report provides a detailed description of L., a young girl with a late diagnosis of ASD who also developed unspecific depressive mood disorder and ARFID in co-occurrence. After the diagnosis of ASD, L. underwent multiple evaluations to address emerging psychiatric co-occurrences and symptom exacerbation, and in order to develop the most effective integrated treatment.</p><p><strong>Conclusion: </strong>The case of L. expands the knowledge on the phenotype of Autistic females and exemplifies how delayed diagnosis may exacerbate functioning differences and increase the camouflage phenomenon. Additionally, it underscores the importance of improving tailored evaluation, combined treatment plans, with both cognitive-behavioral therapy and drugs, and monitoring the evolving patterns of Autistic manifestations and associated psychiatric co-occurrences.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"15 ","pages":"1447562"},"PeriodicalIF":3.2,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11803446/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bibliometric and visual analysis of suicide in aged people over the past 20 years.","authors":"Shao-Kui Kan, Ying-Li Zhang, Xue-Xia Bai, Bo Peng","doi":"10.3389/fpsyt.2025.1469853","DOIUrl":"10.3389/fpsyt.2025.1469853","url":null,"abstract":"<p><strong>Background: </strong>The rapid aging of the global population presents pressing public health challenges, notably an increase in suicide rates among older adults. Despite this critical issue, there is a scarcity of comprehensive assessments regarding the existing literature on suicide within this demographic. This study seeks to employ bibliometric analysis and knowledge mapping to elucidate prevailing research trends and the overall status of this field.</p><p><strong>Methods: </strong>We performed a comprehensive computer-based search of the Web of Science Core Collection to identify relevant articles and reviews concerning suicide in the elderly. A bibliometric analysis was conducted, examining various aspects including countries or regions, institutions, authors, journals, keywords, and references. This analysis utilized tools such as CiteSpace, VOSViewer, Pajek, and Excel 365 to facilitate a thorough assessment.</p><p><strong>Results: </strong>The analysis covered 1,116 publications from 2005 to 2024. The annual number of publications showed a fluctuating upward trend, with notable decreases in 2007, 2012, 2015, 2017, and 2022, and increases in 2009, 2013, 2016, and 2019, peaking at 121 in 2021, with citations reaching 4,741 in 2022, but declining since then. The United States stands out as the most productive and influential country in the field, boasting the highest number of publications and citations. The country is home to institutions leading in both publication and citation metrics. Prominent authors contributing significantly to this domain include Conwell Yeates, Van Orden Kimberly A., and Waern Margda. Key journals disseminating crucial research are the Journal of Affective Disorders, American Journal of Geriatric Psychiatry, and Lancet. Frequent keywords in this field encompass depression, suicidal ideation, suicide, older-adults, risk, risk factors, prevalence, older adults, ideation, behavior, health, mental health, life, age, people, prevention, symptoms, scale, population, and elderly. The contemporary research emphasis is primarily on identifying, treating, and preventing the suicide risk associated with depression in older adults.</p><p><strong>Conclusions: </strong>This study highlights the growing research focus on suicide in older adults, particularly related to depression and the identification, treatment, and prevention of suicide risk. The findings underscore the need for targeted prevention strategies and further investigation in this critical public health area.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"16 ","pages":"1469853"},"PeriodicalIF":3.2,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11802570/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}