Frontiers in PsychiatryPub Date : 2025-07-01eCollection Date: 2025-01-01DOI: 10.3389/fpsyt.2025.1594692
Agnieszka Ewa Burnos, Gabriela Kopacz
{"title":"Religiosity of adults on the autism spectrum: a cognitive and empirical analysis.","authors":"Agnieszka Ewa Burnos, Gabriela Kopacz","doi":"10.3389/fpsyt.2025.1594692","DOIUrl":"10.3389/fpsyt.2025.1594692","url":null,"abstract":"<p><p>This article presents a narrative theoretical and empirical review of religiosity in adults on the autism spectrum. Religiosity is defined as an individual set of beliefs and practices proposed by a religious institution or group. This topic is critical for better understanding the religious and spiritual needs of autistic individuals, as well as the barriers they may face in developing and practicing religiosity. Theoretical accounts of the relationship between the social and cognitive characteristics of individuals on the autism spectrum and their religious attitudes and behaviors are examined. These include theory of mind, weak central coherence, executive function deficits, restricted interests, need for predictability, cognitive rigidity, and the broken mirror hypothesis. Alongside these conceptual frameworks, the article reviews findings from nine empirical studies. The emerging picture of religiosity among autistic adults is complex and marked by inconsistency. The central hypothesis-that impairments in mentalizing reduce religiosity-has not been unequivocally supported by empirical evidence. Similarly, results regarding the overall level of religiosity and representations of God in autistic versus neurotypical individuals are inconclusive. The article offers a synthetic overview of existing hypotheses and provides recommendations for the design of future research in this area.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"16 ","pages":"1594692"},"PeriodicalIF":3.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12259667/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Frontiers in PsychiatryPub Date : 2025-07-01eCollection Date: 2025-01-01DOI: 10.3389/fpsyt.2025.1615271
Chunli Yan, Yane Chu
{"title":"Psychological capital mediates the relationship between medication adherence and cancer-related fatigue in breast cancer patients undergoing long-term treatment.","authors":"Chunli Yan, Yane Chu","doi":"10.3389/fpsyt.2025.1615271","DOIUrl":"10.3389/fpsyt.2025.1615271","url":null,"abstract":"<p><strong>Background: </strong>Breast cancer is one of the most prevalent malignant tumors among women worldwide. Although long-term pharmacological treatment has substantially improved survival rates, it is often accompanied by psychological burdens, including cancer-related fatigue (CRF) and diminished adherence to therapy. CRF is a pervasive and debilitating symptom that adversely affects physical functioning and emotional well-being. Psychological capital (PsyCap), a construct encompassing self-efficacy, hope, optimism, and resilience, has been shown to enhance treatment engagement and promote mental health. However, its role as a potential psychological mediator between medication adherence and CRF is yet to be thoroughly investigated.</p><p><strong>Objective: </strong>To investigate the mediating role of PsyCap in the relationship between medication adherence and CRF in patients with breast cancer undergoing long-term treatment.</p><p><strong>Methods: </strong>A total of 100 breast cancer patients admitted between June 2022 and June 2024 were recruited using convenience sampling. Data from 90 valid responses were analyzed. Participants completed the PsyCap Questionnaire (PCQ-24), Self-Reported Medication Adherence Rating Scale (SR-MARS), and CRF Scale (CFS). Pearson's correlation analysis was used to assess associations among variables. A mediation analysis was conducted using the bootstrap method with 5,000 resamples.</p><p><strong>Results: </strong>The mean scores for PsyCap, medication adherence, and CRF were 86.65 ± 8.37, 5.36 ± 1.12, and 36.77 ± 5.98, respectively. PsyCap was positively correlated with medication adherence (<i>r</i> = 0.994, p < 0.05) and negatively correlated with CRF (<i>r</i> = -0.992, p < 0.05). Medication adherence was also negatively correlated with CRF (<i>r</i> = -0.994, p < 0.05). Mediation analysis confirmed that PsyCap significantly mediated the relationship between medication adherence and CRF (indirect effect = 0.357, 95% CI did not include zero), accounting for 55.68% of the total effect.</p><p><strong>Conclusion: </strong>PsyCap partially mediated the association between medication adherence and CRF. Interventions aimed at enhancing PsyCap may improve adherence and reduce CRF in breast cancer patients receiving long-term pharmacotherapy.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"16 ","pages":"1615271"},"PeriodicalIF":3.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12259705/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Frontiers in PsychiatryPub Date : 2025-07-01eCollection Date: 2025-01-01DOI: 10.3389/fpsyt.2025.1493265
Ioannis Malogiannis, Lida Anagnostaki, Maria Aspradaki, Panagiotis Aristotelidis, Katerina Karambela, Maria Amperiadou, Vasiliki Efthymiou, Phaithra Kriezi, Ioanna Theodoridou, Pentagiotissa Stefanatou, George Konstantakopoulos, Kyriakos Souliotis, Lily E Peppou, Eleni Giannoulis
{"title":"Borderline personality disorder Athens study: a quasi-experimental pragmatic trial for the assessment of a public, psychodynamic, stepped care service for borderline personality disorder patients.","authors":"Ioannis Malogiannis, Lida Anagnostaki, Maria Aspradaki, Panagiotis Aristotelidis, Katerina Karambela, Maria Amperiadou, Vasiliki Efthymiou, Phaithra Kriezi, Ioanna Theodoridou, Pentagiotissa Stefanatou, George Konstantakopoulos, Kyriakos Souliotis, Lily E Peppou, Eleni Giannoulis","doi":"10.3389/fpsyt.2025.1493265","DOIUrl":"10.3389/fpsyt.2025.1493265","url":null,"abstract":"<p><strong>Background: </strong>Borderline personality disorder (BPD) is a common mental disorder that severely impairs patients' psychosocial functioning and quality of life and results in prolonged use of health services. Although psychotherapy is recommended as the most effective treatment for patients with BPD, their complex emotional needs can be met in everyday clinical practice by developing integrative, holistic, personalized mental health services tailored to their needs.</p><p><strong>Aim and hypothesis: </strong>The aim of our study was to evaluate the effectiveness of a specialized psychodynamic stepped-care service for BPD patients. Our hypothesis is that patients receiving this specialized health-care service will show greater improvement in clinical, functional and quality of life than patients receiving a treatment as usual (TAU) service. In addition, specialized health-care services will prove to be more cost effective.</p><p><strong>Method and design: </strong>A quasi-experimental clinical trial will be conducted. The study is designed to include 212 BPD patients who will be non-randomly assigned to specialized health care services and to two TAU centers. Patients will be recruited at each site following the routine clinical pathways of referral at each center. The primary outcome measures are BPD severity, suicide attempts and hospital admissions. The secondary outcome measures will include measures of general psychopathology, psychosocial functioning, quality of life and retention in treatment. In addition. An economic evaluation from a societal perspective will be conducted.</p><p><strong>Discussion: </strong>The development of complex individualized stepped-whole care public interventions for BPD patients requires extended research in everyday clinical practice conditions. In this study, we describe the design and implementation of a pragmatic trial to evaluate this type of health service for BPD patients, and we discuss the strengths as well as the problems and how these can be mitigated.</p><p><strong>Trial registration: </strong>Clinical Trials gov.: ClinicalTrials.gov ID: NCT06392139 (Protocol ID No. 404/06-07-202).</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"16 ","pages":"1493265"},"PeriodicalIF":3.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12259668/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Frontiers in PsychiatryPub Date : 2025-07-01eCollection Date: 2025-01-01DOI: 10.3389/fpsyt.2025.1574448
Danielle C Barron, Madison P Craft, Emily R Florek, Brianna N Stanley, Alexis M Stoner, Nancy A Paschall, Sarah Newman, Kimberly I Tumlin
{"title":"Effects of therapeutic horsemanship on caregiver stress scores of children with autism.","authors":"Danielle C Barron, Madison P Craft, Emily R Florek, Brianna N Stanley, Alexis M Stoner, Nancy A Paschall, Sarah Newman, Kimberly I Tumlin","doi":"10.3389/fpsyt.2025.1574448","DOIUrl":"10.3389/fpsyt.2025.1574448","url":null,"abstract":"<p><strong>Introduction: </strong>Caregivers (primarily parents) of children with autism spectrum disorder (autism) report higher levels of stress, burn out and depression when compared to caregivers of children without autism. Interventions which incorporate animals have been efficacious in improving well-being for children with autism; however, investigating how caregivers are affected when their children are involved in such programs are a nascent field of inquiry. The objective of this pilot study is to characterize emotional strain and stress in caregivers of children with autism when their child attended a therapeutic horsemanship (TH) program.</p><p><strong>Methods: </strong>Thirteen caregiver-child dyads completed the study. Utilizing a mixed methods approach, caregivers completed the Depression Anxiety Stress Scale (DASS-21) questionnaire prior to and upon completion of their child's participation in TH for a 16-week semester. Semi-structured interviews were performed once during the semester and transcripts were analyzed using thematic analysis.</p><p><strong>Results: </strong>We observed caregivers experienced a statistically significant decrease (p=0.03) in their stress levels over a single semester of TH participation demonstrated by a reduction in DASS-21 stress subcategory (pre intervention mean 12.77 (SD = 9.95), post-intervention mean 8.62 (SD = 10.98). A total of five common themes were identified from the caregivers' interview responses. Of these, four were associated with increased caregiver stress and strain: 1) navigating the care and management of their child's diagnosis; 2) the lack of resources for their child with autism (CWA); 3) managing finances; and 4) caring for more than one child in their household. In contrast, the fifth theme captured a reduction in caregiver stress and strain secondary to their indirect involvement in TH.</p><p><strong>Discussion: </strong>This pilot study successfully captured the indirect effects of a TH program in caregivers of children with autism. Integral to understanding caregiver stress, this study further characterizes how caregiver emotional stress and strain can be impacted as their child builds life skills in TH.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"16 ","pages":"1574448"},"PeriodicalIF":3.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12261109/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Attention-based multi-scale convolution and conformer for EEG-based depression detection.","authors":"Ze Yan, Yumei Wan, Xin Pu, Xiaolin Han, Mingming Zhao, Haiyan Wu, Wentao Li, Xueying He, Yunshao Zheng","doi":"10.3389/fpsyt.2025.1584474","DOIUrl":"10.3389/fpsyt.2025.1584474","url":null,"abstract":"<p><p>Depression is a common mental health issue, and early detection is crucial for timely intervention. This study proposes an end-to-end EEG-based depression recognition model, AMCCBDep, which combines Attention-based Multi-scale Parallel Convolution (AMPC), Conformer, and Bidirectional Gated Recurrent Unit (BiGRU). The AMPC module captures temporal features through multiscale convolutions and extracts spatial features using depthwise separable convolutions, while applying the ECA attention mechanism to weigh key channels, enhancing the model's focus on crucial electrode channels. The Conformer module further captures both global and local temporal dependencies in EEG signals to ensure the capture of long-range dependencies and local patterns. The BiGRU module improves the model's ability to recognize depressive states by utilizing bidirectional modeling. We used the 128-channel resting-state EEG signals from the MODMA dataset, which includes data from 24 depression patients (13 males, 11 females, aged 16 to 56) and 29 healthy individuals (20 males, 9 females, aged 18 to 55). Experimental results show that the AMCCBDep model achieved an accuracy of 98.68% ± 0.45% on the MODMA dataset. The model evaluation results for both 128-channel and 16-channel configurations demonstrate that reducing the number of electrodes has a minimal impact on performance, suggesting that electrode reduction could be considered in practical applications. This model showcases strong potential in advancing depression detection in neuroscience, providing an efficient and scalable solution for clinical and practical applications. Future research will further optimize model performance and explore the impact of reducing the number of electrodes on clinical practice.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"16 ","pages":"1584474"},"PeriodicalIF":3.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12259615/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Frontiers in PsychiatryPub Date : 2025-07-01eCollection Date: 2025-01-01DOI: 10.3389/fpsyt.2025.1573261
Cai Zhang, Zhiqian Zhang, Hanning Lei, Xia Wang, Yun Wang
{"title":"Joint developmental trajectories of depressive symptoms, perceived stress in adolescence and their relationship with smartphone addiction.","authors":"Cai Zhang, Zhiqian Zhang, Hanning Lei, Xia Wang, Yun Wang","doi":"10.3389/fpsyt.2025.1573261","DOIUrl":"10.3389/fpsyt.2025.1573261","url":null,"abstract":"<p><strong>Introduction: </strong>Mental health issues frequently cluster during adolescence, necessitating a deeper understanding of their developmental trajectories and their impact on behavioral outcomes like smartphone addiction. Based on diathesis-stress model and I-PACE model, this study examined the joint trajectories of depressive symptoms, family stress perception, and academic stress perception among adolescents and their relationship with smartphone addiction.</p><p><strong>Methods: </strong>12,074 Chinese adolescents (47.9% girls; <i>M</i> <sub>age</sub> = 12.28 ± 0.45 years) were assessed for depressive symptoms, perceived family stress and academic stress from seventh to ninth grade, with smartphone addiction measured in the final year.</p><p><strong>Results: </strong>Using a group-based multi-trajectory model, five distinct trajectories were identified: Low-Stable (23.8%), Moderate-Stable (45.9%), Moderate-Increasing (14.8%), High-Decreasing (11.2%), and High-Stable (4.3%). Gender differences were evident, as girls were more likely than boys to belong to higher stress or depressive symptoms trajectories compared to the low-stable group. Smartphone addiction scores differed significantly across trajectory groups, ranging from high-stable to low-stable. Girls consistently showed higher smartphone addiction scores, although the interaction between gender and trajectory group was not significant.</p><p><strong>Conclusion: </strong>These findings highlight the importance of recognizing both shared and individual patterns of adolescent mental health development. Schools and families should implement tailored interventions to address depression and stress, particularly for vulnerable groups such as girls, to mitigate the risk of smartphone addiction and promote overall mental well-being.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"16 ","pages":"1573261"},"PeriodicalIF":3.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12259693/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Frontiers in PsychiatryPub Date : 2025-07-01eCollection Date: 2025-01-01DOI: 10.3389/fpsyt.2025.1596132
Varsha D Badal, Caitlyn Tran, Haze Brown, Danielle K Glorioso, Rebecca Daly, Anthony J A Molina, Alison A Moore, Erhan Bilal, Ellen E Lee, Colin A Depp
{"title":"Audio and linguistic prediction of objective and subjective cognition in older adults: what is the role of different prompts?","authors":"Varsha D Badal, Caitlyn Tran, Haze Brown, Danielle K Glorioso, Rebecca Daly, Anthony J A Molina, Alison A Moore, Erhan Bilal, Ellen E Lee, Colin A Depp","doi":"10.3389/fpsyt.2025.1596132","DOIUrl":"10.3389/fpsyt.2025.1596132","url":null,"abstract":"<p><strong>Background: </strong>Psycho-linguistic and audio data derived from speech may be useful in screening and monitoring cognitive aging. However, there are gaps in understanding the predictive value of different prompts (e.g., open ended or structured) and the relationship of features to subjective versus objective cognition.</p><p><strong>Objective: </strong>To advance understanding of method variation in speech-analysis based psychometry, we evaluated targeted prompts for classification of impaired cognition and cognitive complaints.</p><p><strong>Method: </strong>A sample of 49 older participants (mean age: 76.9, SD: 8.5) completed short interview questions and cognitive assessments. Acoustic and Linguistic Inquiry through Word Counting i.e., LIWC (verbal content-based) features were derived from answers to open ended questions about aging (AG) and the Cookie Theft task (CT). Outcomes were objective cognitive ability measured using Telephone Interview for Cognitive Status (TICS-m), and subjective cognition using Cognitive Failures Questionnaire (CFQ).</p><p><strong>Results: </strong>A combined feature set including acoustic and LIWC (verbal content) yielded excellent classification results for both CFQ and TICS-m. The F1, precision and recall for CFQ elevation was 0.83, 0.85 and 0.82, and for TICS-m cutoff was 0.92, 0.92 and 0.92 respectively (using single learners). Features derived from CT task were of greater relevance to TICS-m classification, while the features from the AG task were of greater relevance to the CFQ classification.</p><p><strong>Conclusion: </strong>Acoustic and psycholinguistic features are relevant to assessment of cognition and subjective cognitive complaints, with combined features performing best. However, subjective and objective cognitions were predicted to differing extents by the different tasks, and the feature sets.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"16 ","pages":"1596132"},"PeriodicalIF":3.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12259555/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Frontiers in PsychiatryPub Date : 2025-07-01eCollection Date: 2025-01-01DOI: 10.3389/fpsyt.2025.1570594
Frank Ho-Yin Lai, Benjamin K Yee, Eileen H J Wang, Joe Butler, Andrew Graham, Eddie Yip-Kuen Hai, Cath Darling, Stephanie Whittington, Julie-Anne Lowe
{"title":"Cognition in virtual reality: assessing user acceptability and feasibility of virtual reality cognitive screening for older adults.","authors":"Frank Ho-Yin Lai, Benjamin K Yee, Eileen H J Wang, Joe Butler, Andrew Graham, Eddie Yip-Kuen Hai, Cath Darling, Stephanie Whittington, Julie-Anne Lowe","doi":"10.3389/fpsyt.2025.1570594","DOIUrl":"10.3389/fpsyt.2025.1570594","url":null,"abstract":"<p><strong>Introduction: </strong>The global demographic shift towards an older population necessitates innovative methods to assess cognitive abilities, particularly spatial working memory, which is crucial for daily living and early detection of neurocognitive conditions like Alzheimer's disease.</p><p><strong>Methods: </strong>This qualitative study utilised the Virtual Reality Working Memory Task (VRWMT), a semi-immersive VR activity using keyboard navigation, to assess spatial working memory in older adults. Participants were recruited from community centres and categorised by age and technological familiarity. Focus groups evaluated user perceptions based on the Technology Acceptance Model constructs: Perceived Usefulness, Perceived Ease of Use, Attitude Toward Usage, and Behavioural Intention to Use. The study aimed to assess the acceptability and feasibility of VRWMT across diverse populations, examining its navigational simplicity, emotional engagement, and willingness to endorse VRWMT for routine cognitive assessments.</p><p><strong>Results: </strong>Findings indicated significant variations in perceived usefulness, ease of use, attitude toward using, and behavioural intention to use across different age groups and socio-demographic characteristics. High-technology-familiarity participants found VRWMT easy to use and engaging, while those with low familiarity struggled with navigation and engagement. Socio-demographic factors such as limited digital literacy and lack of standby support impact technology adoption. Higher technological familiarity leads to better acceptance and feasibility of VRWMT.</p><p><strong>Discussion: </strong>VRWMT can enhance cognitive health monitoring and therapeutic interventions. The results highlighted that personalised pathways and user-friendly interfaces can improve accessibility and engagement, making VRWMT a valuable tool for cognitive assessments, as part of Occupational Therapy, in diverse populations.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"16 ","pages":"1570594"},"PeriodicalIF":3.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12261108/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Frontiers in PsychiatryPub Date : 2025-07-01eCollection Date: 2025-01-01DOI: 10.3389/fpsyt.2025.1568777
José Ángel Alcalá, Verónica Olmo Dorado, Guadalupe Del Pilar Arilla Herrera, Silvia López Chamón, Vicente Gasull Molinera
{"title":"Optimizing the diagnosis and treatment of depression in primary care: the emerging role of vortioxetine treatment.","authors":"José Ángel Alcalá, Verónica Olmo Dorado, Guadalupe Del Pilar Arilla Herrera, Silvia López Chamón, Vicente Gasull Molinera","doi":"10.3389/fpsyt.2025.1568777","DOIUrl":"10.3389/fpsyt.2025.1568777","url":null,"abstract":"<p><p>The management of patients with major depressive disorder (MDD) in primary care (PC) represents a significant challenge and a great opportunity for early and effective intervention. Primary care physicians, as first-line physicians, play a key role in the identification, diagnosis and initial treatment of depression, often being the first and sometimes the only point of contact for these patients with the healthcare system. In this context, the search for effective and well-tolerated therapeutic strategies is constant, and vortioxetine represents a good pharmacological option within the therapeutic armamentarium available to the PC physician. This article explores best practices in the management of MDD from the PC perspective, addressing the specific challenges faced by these professionals and examining the potential role of vortioxetine in the treatment of different patient profiles.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"16 ","pages":"1568777"},"PeriodicalIF":3.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12259655/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Frontiers in PsychiatryPub Date : 2025-07-01eCollection Date: 2025-01-01DOI: 10.3389/fpsyt.2025.1579144
Ama Kissi, Sean Carey, Dries Debeer, Dimitri M L Van Ryckeghem, Adam Hirsh, Tine Vervoort
{"title":"Racialized disparities in pain and pain care among Belgian youth.","authors":"Ama Kissi, Sean Carey, Dries Debeer, Dimitri M L Van Ryckeghem, Adam Hirsh, Tine Vervoort","doi":"10.3389/fpsyt.2025.1579144","DOIUrl":"10.3389/fpsyt.2025.1579144","url":null,"abstract":"<p><strong>Introduction: </strong>Research highlights racialized inequities in pain and pain care, yet the experiences of youth-particularly in Europe-remain largely understudied. The current study addressed this gap by examining differences in perceived racialized discrimination in pain care and pain outcomes (i.e., pain intensity over the past two weeks and six months, pain frequency over the past six months, and pain tolerance) among Black/Brown and White youth in Belgium. Additionally, we explored whether perceived racialized discrimination mediated the relationship between racialized identity and pain outcomes.</p><p><strong>Methods: </strong>Seventy-six youth (52 girls, 17 boys, 2 non-binary individuals) aged 8-17 (<i>M</i> <sub>age</sub> = 15.17; <i>SD<sub>age</sub></i> = 2.48) completed a cold pressor task to assess pain tolerance. Participants also reported their experiences of racialized discrimination in pain care, their pain intensity over the past two weeks and six months, and their pain frequency over the past six months.</p><p><strong>Results: </strong>Results indicated that Black/Brown youth reported greater perceived racialized discrimination in pain care and demonstrated lower pain tolerance than White youth. No significant group differences were observed for the other three pain outcomes. Perceived racialized discrimination in pain care only mediated the relationship between racialized identity and pain intensity over the past two weeks.</p><p><strong>Discussion: </strong>These findings suggest that racialized disparities in pain and pain care exist among youth living in Belgium. However, given the relatively small sample size, the results should be interpreted with caution. Additional research on racialized disparities in pain and pain care among youth using larger and more diverse samples is warranted.</p>","PeriodicalId":12605,"journal":{"name":"Frontiers in Psychiatry","volume":"16 ","pages":"1579144"},"PeriodicalIF":3.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12259640/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}