General and comparative endocrinology最新文献_第5页

A novel culture method for Rana [Lithobates] catesbeiana olfactory epithelium reveals differential effects of transcriptional and translational inhibitors on the temperature-dependent induction of thyroid hormone-responsive transcripts 一种新的Rana [Lithobates] catesbeiana嗅上皮培养方法揭示了转录和翻译抑制剂对温度依赖性诱导甲状腺激素应答转录物的差异作用。

IF 2.1 3区医学

General and comparative endocrinology Pub Date : 2026-06-01 Epub Date: 2026-08-04 DOI: 10.1016/j.ygcen.2026.114988

Emma M. Field, Caren C. Helbing

{"title":"A novel culture method for Rana [Lithobates] catesbeiana olfactory epithelium reveals differential effects of transcriptional and translational inhibitors on the temperature-dependent induction of thyroid hormone-responsive transcripts","authors":"Emma M. Field, Caren C. Helbing","doi":"10.1016/j.ygcen.2026.114988","DOIUrl":"10.1016/j.ygcen.2026.114988","url":null,"abstract":"<div><div>Amphibian organ culture is invaluable for gaining insight into thyroid hormone (TH) action. The olfactory epithelium (OE) of <em>Rana (aka Aquarana or Lithobates) catesbeiana</em> tadpoles is a highly TH-sensitive tissue that regulates essential survival behaviors and undergoes drastic remodeling during TH-dependent metamorphosis. These features make it a valuable bioindicator for normal and disrupted TH action. To our knowledge, we developed and validated the first successful <em>ex vivo</em> culture method for anuran tadpole olfactory epithelium. Pairs of OE-containing principal cavities from premetamorphic tadpoles were excised, each cavity cut in half, and exposed to 10 nM 3,5,3′-triiodothyronine (T<sub>3</sub>) or solvent control at 24 °C for 24 h. Each half cavity showed consistent enrichment of the olfactory marker <em>omp</em> compared to back skin. Robust and reproducible TH responses were observed in individual, unpooled cultured olfactory epithelium (C-OE) as measured by reverse transcription-quantitative polymerase chain reaction of TH-responsive transcripts <em>thra</em>, <em>thrb</em>, and <em>thibz</em>. No spatial variation in hormone sensitivity within the principal cavity was observed supporting the use of repeated-measures statistics while capturing biological variation between animals. To probe early TH signaling events, C-OE and cultured back skin (C-skin) were treated with T<sub>3</sub> in the presence of transcriptional and translational inhibitors at 24 °C or 4 °C. The cold condition represents a metamorphic stasis period during which the TH signal is initiated, but metamorphosis does not proceed. Notably, TH-induction of <em>thibz</em> at 4 °C was unaffected by transcriptional inhibition in both tissues, suggesting that mechanisms other than RNA synthesis may be driving the increase in transcript abundance.</div></div>","PeriodicalId":12582,"journal":{"name":"General and comparative endocrinology","volume":"384 ","pages":"Article 114988"},"PeriodicalIF":2.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148683681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The sole Drosophila melanogaster insulin receptor gene mediates metabolism and movement regulating lipid and carbohydrate stores, sleep, and motor activity 唯一的黑腹果蝇胰岛素受体基因介导代谢和运动，调节脂质和碳水化合物储存、睡眠和运动活动。

IF 2.1 3区医学

General and comparative endocrinology Pub Date : 2026-06-01 Epub Date: 2026-08-06 DOI: 10.1016/j.ygcen.2026.114984

Jéssica Paloma Álvarez-Rendón, Juan Rafael Riesgo-Escovar

{"title":"The sole Drosophila melanogaster insulin receptor gene mediates metabolism and movement regulating lipid and carbohydrate stores, sleep, and motor activity","authors":"Jéssica Paloma Álvarez-Rendón, Juan Rafael Riesgo-Escovar","doi":"10.1016/j.ygcen.2026.114984","DOIUrl":"10.1016/j.ygcen.2026.114984","url":null,"abstract":"<div><div>The insulin signaling pathway is a core and evolutionarily conserved signal transduction network. Here we study hypomorphic mutant conditions in the sole insulin receptor gene (<em>Inr</em>) in the fruit fly <em>Drosophila melanogaster</em>, placed at the beginning of the signaling cascade where it mediates the effects from the seven <em>Drosophila</em> insulin-like peptides. As such, it sits at a nodal point where signaling must pass to ensure and carry out all the functions ascribed to this anabolic pathway. We find that these mutant flies, while viable, exhibit hyperactivity and accumulate glycogen and body lipids. The hyperactivity phenotype was characterized in detail and is significantly different from controls both measuring it in several days' spells, or when done in a more detailed fashion in shorter time periods (twenty-five minutes). The proportion of time spent sleeping is also altered, highlighting the robust role that the insulin pathway has not only regulating metabolism but also behavior. When confronted with mild pro-oxidative conditions, these flies and control wildtype flies have reduced lifespans as well. The metabolic dysregulation is rescued when the <em>Inr</em> mutant flies are also heterozygous for <em>keap1</em>, a negative regulator of the <em>Nrf2</em> pathway, while the antioxidant response and the activity/sleep levels exhibit only partial and sexually dimorphic improvements. Transcriptomic analyses of <em>Inr</em> mutants show that many metabolism and hormonal signaling genes are dysregulated.</div></div>","PeriodicalId":12582,"journal":{"name":"General and comparative endocrinology","volume":"384 ","pages":"Article 114984"},"PeriodicalIF":2.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148684268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative analysis of the expression and localization of prolactin 1A and 1B in the pituitary gland of the red-bellied newt Cynops pyrrhogaster 催乳素1A和1B在红腹蝾螈脑垂体中表达和定位的比较分析。

IF 2.1 3区医学

General and comparative endocrinology Pub Date : 2026-06-01 Epub Date: 2026-07-14 DOI: 10.1016/j.ygcen.2026.114978

Takatoshi Ikeda, Yuriko Sudo, Momoka Itao, Yousuke Tsuneoka, Masahiro Matsuno, Shawichi Iwamuro, Reiko Okada, Sakae Kikuyama, Itaru Hasunuma

{"title":"Comparative analysis of the expression and localization of prolactin 1A and 1B in the pituitary gland of the red-bellied newt Cynops pyrrhogaster","authors":"Takatoshi Ikeda, Yuriko Sudo, Momoka Itao, Yousuke Tsuneoka, Masahiro Matsuno, Shawichi Iwamuro, Reiko Okada, Sakae Kikuyama, Itaru Hasunuma","doi":"10.1016/j.ygcen.2026.114978","DOIUrl":"10.1016/j.ygcen.2026.114978","url":null,"abstract":"<div><div>The authentic prolactin (PRL) designated PRL1 is a multifunctional hormone secreted by the anterior pituitary gland of vertebrates. The PRL1 gene exists in two forms: fish-type PRL1 gene (<em>PRL1B</em>) and tetrapod-type PRL1 gene (<em>PRL1A</em>). It has been proposed that <em>PRL1B</em> gene underwent duplication during the early amphibian lineage. Subsequently, the ancestral gene (<em>PRL1B</em>) was lost in amniotes, while the newly duplicated gene (<em>PRL1A</em>) was retained. Notably, only amphibians possess both <em>PRL1B</em> and <em>PRL1A</em> genes. In the anuran amphibian bullfrog, <em>PRL1A</em> gene expression is low during the pre- and prometamorphic stages, gradually increasing toward the end of the metamorphic climax stage. In contrast, <em>PRL1B</em> gene expression is relatively high during the early metamorphic stages but significantly declines during the metamorphic climax stage and becomes undetectable after completion of metamorphosis. These differential expression patterns suggest a functional transition of PRL1 paralogs associated with the shift from aquatic to terrestrial life. However, data on <em>PRL1B</em> expression in urodele amphibians remain limited. In this study, we cloned the <em>PRL1B</em> cDNA from the urodele amphibian, the red-bellied newt (<em>Cynops pyrrhogaster</em>) and analyzed its expression in the pituitary gland. Unlike in anuran bullfrog, PRL1B is expressed as the transcript and protein in the adult pituitary of this urodele species, suggesting that the regulatory mechanism controlling <em>PRL1B</em> expression in urodeles differs from that in anurans. This is the first report demonstrating the existence of PRL1B in urodeles in the form of protein as well as mRNA.</div></div>","PeriodicalId":12582,"journal":{"name":"General and comparative endocrinology","volume":"383 ","pages":"Article 114978"},"PeriodicalIF":2.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148445666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessing staining methods for amphibian sperm viability and morphological assessment: several different methods are acceptable to assess amphibian sperm quality 评估两栖动物精子活力和形态评估的染色方法：几种不同的方法可用于评估两栖动物精子质量。

IF 2.1 3区医学

General and comparative endocrinology Pub Date : 2026-06-01 Epub Date: 2026-07-26 DOI: 10.1016/j.ygcen.2026.114983

Shannon Murphy, Nina Ross, Natalie Tear, Claudia Hui Wen Khoo, Daniel Vivas Barreto, Dilakni D. Udapitya, Laura A. Brannelly

{"title":"Assessing staining methods for amphibian sperm viability and morphological assessment: several different methods are acceptable to assess amphibian sperm quality","authors":"Shannon Murphy, Nina Ross, Natalie Tear, Claudia Hui Wen Khoo, Daniel Vivas Barreto, Dilakni D. Udapitya, Laura A. Brannelly","doi":"10.1016/j.ygcen.2026.114983","DOIUrl":"10.1016/j.ygcen.2026.114983","url":null,"abstract":"<div><div>Assisted reproduction methodologies are essential to protect species from extinction. But to improve reproductive outcomes, we need to understand gamete quality. Gamete quality assays are powerful functional endpoints for comparative endocrinology, especially when they are integrated with hormone measurements and experimental manipulations. However, the methodologies for assessing amphibian gamete quality do not have published validation or comparisons within the literature. In this study we analysed sperm samples from two bell frog species, looking at morphology (measuring sperm head and sperm tail length) using both wet mounts and dry mounts of three different stains (unstained mounts, Coomassie blue and eosin nigrosin). We also assessed viability in the same sperm samples using three different preparations (eosin nigrosin dry mount, eosin nigrosin wet mount, and fluorescent SYBR-14 propidium iodide). We found that the methods varied in mean morphological measurements. For example, sperm tail lengths were measured longer when the slides were dry mounts, and when the eosin nigrosin stain was used. There were differences among species as well, where, for example, stain type influenced the sperm head length in one species, but not in the other species. Importantly, all methods had similar variance, indicating that all staining techniques are suitable given that the methods used are consistent within a study. For viability assessment, the dried eosin nigrosin staining method showed lower viability, while the wet mount of eosin nigrosin and the fluorescent SYBR-14 propidium iodide stain were statistically equivalent. These results indicate that there are a wide range of methodologies that can be used for sperm quality assessment of amphibian sperm, and researchers must choose the methodology best suited for the study.</div></div>","PeriodicalId":12582,"journal":{"name":"General and comparative endocrinology","volume":"384 ","pages":"Article 114983"},"PeriodicalIF":2.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148591223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Profiles in comparative endocrinology: Louis J. Guillette, Jr. 比较内分泌学简介：Louis J. Guillette, Jr。

IF 2.1 3区医学

General and comparative endocrinology Pub Date : 2026-05-01 Epub Date: 2026-05-22 DOI: 10.1016/j.ygcen.2026.114949

Jerrold J. Heindel, Mark A. Sheridan

引用次数: 0

Nonapeptide modulation of looming-induced responses in male Betta splendens 雄性锦绣斗鱼若虫诱导反应的非肽调节。

IF 2.1 3区医学

General and comparative endocrinology Pub Date : 2026-05-01 Epub Date: 2026-06-26 DOI: 10.1016/j.ygcen.2026.114965

Bianca Fusani, Sara D. Cardoso, Andreia Ramos, David Gonçalves

{"title":"Nonapeptide modulation of looming-induced responses in male Betta splendens","authors":"Bianca Fusani, Sara D. Cardoso, Andreia Ramos, David Gonçalves","doi":"10.1016/j.ygcen.2026.114965","DOIUrl":"10.1016/j.ygcen.2026.114965","url":null,"abstract":"<div><div>The looming stimulus is a widely used paradigm for investigating defensive behaviours in prey-predator contexts, as it simulates an approaching threat through the rapid expansion of a dark disk. Such stimuli typically evoke fight, flight, or freeze responses. In the present study, the role of the nonapeptides oxytocin and vasotocin, both known for their roles in social behaviour and stress regulation, in the behavioural and endocrine response to a looming stimulus in the Siamese fighting fish <em>Betta splendens</em> was assessed. Fish displayed pronounced freezing behaviour and the expression of conspicuous body stripes in response to a 10-min looming stimulus. Despite the marked behavioural reaction, no concomitant changes in plasma cortisol levels were recorded. The oxytocin receptor antagonist (L-368,899) did not affect the behavioural response, whereas treatment with the vasotocin receptor antagonist Manning compound enhanced fight and reduced flight responses. None of the nonapeptides modulated post-looming plasma cortisol levels. These findings provide new insights into the expression and regulation of stripe patterns in <em>B. splendens</em>, a phenomenon previously noted in aquaculture and behavioural studies but not quantitatively described, and highlight the involvement of the vasotocin system in the modulation of defensive strategies.</div></div>","PeriodicalId":12582,"journal":{"name":"General and comparative endocrinology","volume":"382 ","pages":"Article 114965"},"PeriodicalIF":2.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148338199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Circulating testosterone is not associated with social challenge or aggression in female northern house wrens (Troglodytes aedon) 雌性北方鹪鹩（Troglodytes aedon）的循环睾酮与社会挑战或攻击无关。

IF 2.1 3区医学

General and comparative endocrinology Pub Date : 2026-05-01 Epub Date: 2026-06-11 DOI: 10.1016/j.ygcen.2026.114961

Cara A. Krieg, Nora H. Prior, Gregory F. Ball, Karan J. Odom

{"title":"Circulating testosterone is not associated with social challenge or aggression in female northern house wrens (Troglodytes aedon)","authors":"Cara A. Krieg, Nora H. Prior, Gregory F. Ball, Karan J. Odom","doi":"10.1016/j.ygcen.2026.114961","DOIUrl":"10.1016/j.ygcen.2026.114961","url":null,"abstract":"<div><div>Mechanisms that coordinate appropriate behavioral responses to social competition are important for both sexes. Males in many species show a seasonal peak in baseline circulating testosterone (T) concentrations at times when social challenges are more frequent with additional acute elevation in T following competitive interactions. Females in some species show the same patterns, while others do not, making females interesting test cases to evaluate these mechanisms. Here we used three approaches to investigate the interrelationship among circulating T, social challenge, and aggression in female northern house wrens (<em>Troglodytes aedon</em>), a species where female aggression confers a variety of fitness benefits. First, we compared circulating T concentration after a simulated territorial intrusion to T in unchallenged females to determine if T responds to social challenge. Second, we compared T concentrations between females that responded to simulated female intrusions with different levels of aggressive intensity to determine if aggressive behavior relates to T concentrations. Third, we compared natural T concentrations across breeding stages to determine if T is elevated during stages when competition is most common. Overall, female circulating T concentrations were quite low. Neither social challenge nor breeding stage had any impact on T concentrations. Likewise, the intensity of a female's aggressive response to simulated female intruders was unrelated to T. Our results indicate that house wrens may be one of a growing number of species where females mediate competitive behavior through alternative circulating signals or local mechanisms at target tissues.</div></div>","PeriodicalId":12582,"journal":{"name":"General and comparative endocrinology","volume":"382 ","pages":"Article 114961"},"PeriodicalIF":2.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148224395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nucleobindin-derived peptides and stress regulation in vertebrates 核结合蛋白衍生肽和脊椎动物的应激调节。

IF 2.1 3区医学

General and comparative endocrinology Pub Date : 2026-05-01 Epub Date: 2026-06-12 DOI: 10.1016/j.ygcen.2026.114960

Paalki Sethi, Atefeh Nasri, Suraj Unniappan

{"title":"Nucleobindin-derived peptides and stress regulation in vertebrates","authors":"Paalki Sethi, Atefeh Nasri, Suraj Unniappan","doi":"10.1016/j.ygcen.2026.114960","DOIUrl":"10.1016/j.ygcen.2026.114960","url":null,"abstract":"<div><div>Stress response entails a complex array of interactions between the neuroendocrine and nervous systems. When a sensory stimulus is perceived as stressful, the brain triggers a response controlled by two key neuroendocrine systems: the sympathetic pathways for the “fight or flight” response, and the hypothalamus-pituitary-adrenal (HPA) axis, for a long-term stress response. Growing evidence suggests that nucleobindin (Nucb)-derived peptides nesfatin-1 and nesfatin-1-like peptide (NLP), two anorexigens and metabolic regulators, are also involved in stress regulation. Nesfatin-1 stimulates corticotropin-releasing hormone (CRH) in the hypothalamus to induce stress and satiety. Nesfatin-1 and NLP activate the stress axis, by stimulating adrenocorticotropic hormone (ACTH) synthesis and through the modulation of cortisol synthesis. Nesfatin-1 elicits stress behavior, such as anxiety and depression. Nesfatin-1 and NLP regulate both stress and metabolism, suggesting their role in interlinking these processes. This review discusses the involvement of nesfatin-1 and NLP in stress-related pathways in vertebrates, their mechanism of action, as well as existing knowledge gaps that warrant further research.</div></div>","PeriodicalId":12582,"journal":{"name":"General and comparative endocrinology","volume":"382 ","pages":"Article 114960"},"PeriodicalIF":2.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148239138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phytochemicals as eco-friendly modulators of ovarian vitellogenesis and reproductive efficiency in aquaculture 植物化学物质作为水产养殖中卵巢卵黄发生和生殖效率的生态友好调节剂。

IF 2.1 3区医学

General and comparative endocrinology Pub Date : 2026-05-01 Epub Date: 2026-06-17 DOI: 10.1016/j.ygcen.2026.114964

Manjula Elumalai, Shobana Sampath

{"title":"Phytochemicals as eco-friendly modulators of ovarian vitellogenesis and reproductive efficiency in aquaculture","authors":"Manjula Elumalai, Shobana Sampath","doi":"10.1016/j.ygcen.2026.114964","DOIUrl":"10.1016/j.ygcen.2026.114964","url":null,"abstract":"<div><div>The search for natural alternatives to chemical additives and artificial hormones to enhance reproductive function in aquatic animals is driven by demand for eco-friendly aquaculture. This review explores how bioactive plant compounds can enhance ovarian vitellogenesis and reproductive efficiency in crustaceans and finfish.</div><div>Vitellogenesis is regulated by the hypothalamic-pituitary-gonadal axis, controlling yolk protein deposition and embryogenesis. While synthetic hormones have significant effects, their environmental and health impacts have sparked interest in phytochemicals such as carotenoids, flavonoids, alkaloids, and phytoestrogens. These compounds can stimulate vitellogenin production, boost reproductive performance, and improve egg quality through immunomodulatory, hormone-mimetic, and antioxidant activities that reduce oxidative stress.</div><div>Plant extracts like Moringa oleifera, Eurycoma longifolia, and Cyperus spp. boost reproductive maturity and larval survival. The review highlights their cost-effectiveness, biodegradability, and cultural acceptance aligned with sustainable aquaculture demands. Challenges include variation in bioactivity, lack of standardized protocols, and species-specific responses. Future research should explore nanotechnology, omics, and precision extraction to enhance the applications of phytochemicals. Combining traditional knowledge with modern science can improve aquaculture productivity for environmental and food security.</div></div>","PeriodicalId":12582,"journal":{"name":"General and comparative endocrinology","volume":"382 ","pages":"Article 114964"},"PeriodicalIF":2.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148271057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterizing the annual cycle of steroid hormones in males from an invasive vertebrate (Python bivittatus) of management concern 描述管理关注的侵入性脊椎动物（双维蟒）雄性类固醇激素的年周期。

IF 2.1 3区医学

General and comparative endocrinology Pub Date : 2026-05-01 Epub Date: 2026-06-10 DOI: 10.1016/j.ygcen.2026.114959

Gabriela Logo, Mark R. Sandfoss, Natalie M. Claunch, Andrea F. Currylow, Ian A. Bartoszek, Ian Easterling, Amy A. Yackel Adams, Christina M. Romagosa

{"title":"Characterizing the annual cycle of steroid hormones in males from an invasive vertebrate (Python bivittatus) of management concern","authors":"Gabriela Logo, Mark R. Sandfoss, Natalie M. Claunch, Andrea F. Currylow, Ian A. Bartoszek, Ian Easterling, Amy A. Yackel Adams, Christina M. Romagosa","doi":"10.1016/j.ygcen.2026.114959","DOIUrl":"10.1016/j.ygcen.2026.114959","url":null,"abstract":"<div><div>South Florida's subtropical climate has facilitated the establishment of numerous invasive species, including the Burmese python (<em>Python bivittatus</em>). Despite decades of efforts to manage the invasive python population across South Florida, we lack a comprehensive understanding of their reproductive physiology, limiting the development of targeted control strategies. Here, we characterized seasonal patterns of testosterone (T) and corticosterone (CORT) in free-ranging adult male pythons and evaluated environmental correlates of hormone variation. Results indicate that T peaks before the onset of the breeding season and declines through the season to baseline levels in the non-breeding season. CORT did not show a clear seasonal trend but showed greater variability during the breeding season. These findings reveal that photoperiod and ambient temperature are key environmental correlates of male hormone cycles, contributing to our understanding of the endocrine phenology of a tropical ectotherm in a novel environment.</div></div>","PeriodicalId":12582,"journal":{"name":"General and comparative endocrinology","volume":"382 ","pages":"Article 114959"},"PeriodicalIF":2.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148217510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0