Frontiers in Surgery最新文献

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Salivary microRNAs for oral cancer and oral potentially malignant disorder triage: a scoping review and evidence map. 口腔癌和口腔潜在恶性疾病分诊的唾液微小rna:范围回顾和证据图谱。
IF 1.9 4区 医学
Frontiers in Surgery Pub Date : 2026-10-02 eCollection Date: 2026-01-01 DOI: 10.3389/fsurg.2026.1949232
Jianbang Ding, Han Jiang, Shanyue Lin, Dinghua Li, Ying Zeng
{"title":"Salivary microRNAs for oral cancer and oral potentially malignant disorder triage: a scoping review and evidence map.","authors":"Jianbang Ding, Han Jiang, Shanyue Lin, Dinghua Li, Ying Zeng","doi":"10.3389/fsurg.2026.1949232","DOIUrl":"10.3389/fsurg.2026.1949232","url":null,"abstract":"<p><strong>Background: </strong>Salivary microRNAs (miRNAs) have been investigated for oral cancer detection, but comparison with healthy volunteers does not establish performance among patients with oral mucosal lesions. This review maps evidence relevant to discrimination between oral squamous cell carcinoma or oral cancer (OSCC/OC) and oral potentially malignant disorders (OPMDs).</p><p><strong>Methods: </strong>The evidence was organized as a scoping review with study-specific diagnostic descriptions. Clinical comparators, assay methods, thresholds, participant overlap and data provenance were charted. No estimates were pooled. Searches were executed on 8 September 2026 in PubMed (<i>n</i> = 487), Web of Science Core Collection (<i>n</i> = 362), Scopus (<i>n</i> = 318) and the Cochrane Central Register of Controlled Trials (<i>n</i> = 34), with 28 additional records identified through citation chasing and reference-list checking, for a total of 1,229 records. After removal of 412 duplicates and 15 records before screening, 802 titles and abstracts were screened; 54 full-text reports were sought, of which 3 could not be retrieved and 51 were assessed. Sixteen sources were included in the evidence map, comprising 13 primary studies and 3 contextual systematic reviews.</p><p><strong>Results: </strong>Three diagnostic reports contained five assay-level results for cancer vs. OPMD or oral lichen planus. A four-miRNA panel was reported to have 90% sensitivity and 82.7% specificity in 50 OC and 52 OPMD participants. Two individual miRNAs evaluated in the same 30 OSCC and 30 OPMD participants each had reported sensitivity of 70% and specificity of 60%. An additional oral lichen planus comparison had uncertain ROC analysis denominators and was retained without reconstructed counts. Repeated assays within a cohort were not considered independent studies. Small selected samples, data-derived thresholds, inconsistent reporting and limited independent validation restricted interpretation.</p><p><strong>Conclusions: </strong>Salivary miRNAs have shown study-specific discrimination between cancer and selected OPMD groups. Evidence does not establish a transportable accuracy estimate or clinical benefit for lesion triage. Prospective evaluation in consecutive lesion cohorts is needed before these assays can inform biopsy, referral or surveillance decisions.</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":"13 ","pages":"1949232"},"PeriodicalIF":1.9,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13671942/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149215793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How well do large language models answer postoperative lumbar fusion questions? A blinded comparative analysis of accuracy, quality, readability, and safety-related content. 大型语言模型如何很好地回答术后腰椎融合问题?准确性、质量、可读性和安全性相关内容的盲法比较分析。
IF 1.9 4区 医学
Frontiers in Surgery Pub Date : 2026-10-01 eCollection Date: 2026-01-01 DOI: 10.3389/fsurg.2026.1932133
Ahmet Kürşat Kara, Ozan Işık
{"title":"How well do large language models answer postoperative lumbar fusion questions? A blinded comparative analysis of accuracy, quality, readability, and safety-related content.","authors":"Ahmet Kürşat Kara, Ozan Işık","doi":"10.3389/fsurg.2026.1932133","DOIUrl":"10.3389/fsurg.2026.1932133","url":null,"abstract":"<p><strong>Background: </strong>Patients recovering from lumbar fusion increasingly seek guidance from large language model (LLM) chatbots when their surgeon is unavailable, but the accuracy, completeness, and safety-related content of such responses have not been compared across models for the postoperative period.</p><p><strong>Objective: </strong>To compare the accuracy, quality, safety-related content, and readability of responses from ChatGPT, Gemini, and Claude to frequently asked postoperative lumbar fusion questions, and to identify the question types for which responses are weakest.</p><p><strong>Methods: </strong>Thirty questions, compiled by three neurosurgeons and grouped into six clinical categories, were submitted to each model, each with a standardized, patient-oriented prompt requesting warning signs. Ninety anonymized, randomized responses were rated independently by three blinded neurosurgeons for accuracy and four quality subdomains (clarity, completeness, relevance, and patient safety) on 4-point scales. Readability (Flesch-Kincaid, Flesch Reading Ease, and Gunning Fog), word count, and responses meeting an operational screening criterion for potential harm were also assessed. Models were compared with Friedman and Holm-corrected pairwise tests.</p><p><strong>Results: </strong>Accuracy was high for all models without significant differences. Quality, clarity, completeness, relevance, and patient safety differed globally, but effect sizes were small (Kendall's <i>W</i>: 0.10-0.21) and, after correction across the six outcome families, only quality and completeness remained significant, with Gemini scoring lower than ChatGPT and Claude. Gemini had the most favorable readability. ChatGPT responses were the shortest (mean 294 vs. 462 and 445 words); length was unrelated to completeness or readability. Two Gemini responses (6.7%) and none from ChatGPT or Claude met a <i>post hoc</i> operational screening criterion for potential harm (a score of ≤2 on accuracy or patient safety from at least one of three raters, without concurrence from the other two); no response was adjudicated as actually harmful. In exploratory question- and category-level analyses, responses tended to be rated highest for standardized questions and lowest for those requiring individualized judgment or interpretation of wound-related symptoms.</p><p><strong>Conclusion: </strong>Responses from contemporary LLMs to common postoperative lumbar fusion questions were generally rated as accurate, with small between-model differences and a model-level divergence between readability and completeness. Because safety-related content was explicitly prompted and no patient outcomes were assessed, these findings describe the quality of safety-related information rather than clinical safety. LLMs may support postoperative patient education but should not replace physician guidance, particularly for warning signs and patient-specific recovery decisions.</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":"13 ","pages":"1932133"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13668492/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149215654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preoperative staging of gastric cancer: a prospective comparison of gastric filling ultrasonography and enhanced CT with implications for surgical decision-making. 胃癌术前分期:胃充盈超声与增强CT的前瞻性比较及其对手术决策的影响。
IF 1.9 4区 医学
Frontiers in Surgery Pub Date : 2026-10-01 eCollection Date: 2026-01-01 DOI: 10.3389/fsurg.2026.1925096
Xinxin Qin, Junmei Zhao, Litao Ge, Song Wu, Xiaofeng Sun, Wei Li
{"title":"Preoperative staging of gastric cancer: a prospective comparison of gastric filling ultrasonography and enhanced CT with implications for surgical decision-making.","authors":"Xinxin Qin, Junmei Zhao, Litao Ge, Song Wu, Xiaofeng Sun, Wei Li","doi":"10.3389/fsurg.2026.1925096","DOIUrl":"10.3389/fsurg.2026.1925096","url":null,"abstract":"<p><strong>Background: </strong>Accurate preoperative staging is essential for optimizing treatment strategies in gastric cancer. While gastric-enhanced CT is widely used, its accuracy remains suboptimal, particularly for early-stage tumors. Gastric filling ultrasonography, a non-invasive technique using oral contrast to displace intraluminal gas, offers potential advantages in mural visualization. This prospective study compared the diagnostic performance of gastric filling ultrasonography and gastric-enhanced CT against postoperative pathological staging.</p><p><strong>Methods: </strong>We enrolled 406 patients with histologically confirmed gastric cancer who underwent both imaging modalities prior to surgery. Preoperative T and N stages assigned by each modality were compared with pathological results. Diagnostic accuracy, sensitivity, specificity, and area under the ROC curve (AUC) were calculated. McNemar's test was used for paired comparisons, DeLong test for AUC comparisons, and Kappa statistics for agreement assessment. Univariate logistic regression identified factors affecting ultrasound accuracy.</p><p><strong>Results: </strong>For T-staging, overall accuracy was 72.7% (295/406) for ultrasound vs. 63.5% (258/406) for CT (<i>P</i> < 0.001). Ultrasound significantly outperformed CT in T1 (81.5% vs. 56.3%, <i>P</i> = 0.009) and T2 (81.1% vs. 67.9%, <i>P</i> < 0.001) stages. For N-staging, accuracy was 82.0% (333/406) for ultrasound vs. 60.1% (244/406) for CT (<i>P</i> < 0.001). Kappa agreement with pathology was substantial for ultrasound T-staging (<i>κ</i> = 0.625) and N-staging (<i>κ</i> = 0.748), compared with moderate agreement for CT (<i>κ</i> = 0.508 and 0.395, respectively). In multivariate analysis, vascular infiltration was the only independent factor associated with ultrasound T-staging accuracy.</p><p><strong>Conclusions: </strong>Gastric filling ultrasonography demonstrates superior accuracy over gastric-enhanced CT for preoperative T1/T2 and N-staging, with substantial agreement with pathological findings. This non-invasive and radiation-free examination method can serve as an effective complement to CT, and is particularly suitable for gastric cancer at the T1 and T2 stages. We have proposed a complementary imaging protocol to assist in surgical decision-making, which is expected to enable clinicians to make more accurate preoperative staging assessments for patients with gastric cancer.</p><p><strong>Registration: </strong>It was registered in the ClinicalTrials.gov (NCT05596864).</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":"13 ","pages":"1925096"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13670109/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149215703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current progress and controversies in thoracic ossification of the ligamentum flavum: pathogenesis, diagnosis and surgical management. 胸椎黄韧带骨化的进展与争议:发病机制、诊断与外科治疗。
IF 1.9 4区 医学
Frontiers in Surgery Pub Date : 2026-10-01 eCollection Date: 2026-01-01 DOI: 10.3389/fsurg.2026.1896885
Guoxing Ding, Huijing Shang, Fuhai Yan, Weijie Cui, Zhi Li, Yiheng Zhang, Zhan Wang, Jie Wen, Yifan Feng, Junxiao Su, Hui Zhang
{"title":"Current progress and controversies in thoracic ossification of the ligamentum flavum: pathogenesis, diagnosis and surgical management.","authors":"Guoxing Ding, Huijing Shang, Fuhai Yan, Weijie Cui, Zhi Li, Yiheng Zhang, Zhan Wang, Jie Wen, Yifan Feng, Junxiao Su, Hui Zhang","doi":"10.3389/fsurg.2026.1896885","DOIUrl":"10.3389/fsurg.2026.1896885","url":null,"abstract":"<p><p>Thoracic ossification of ligamentum flavum (TOLF) is the primary pathological driver of thoracic spinal stenosis (TSS), characterized by insidious clinical onset, high surgical complexity, and a elevated risk of permanent neurological deficits. This systematic review synthesizes the epidemiological landscape and genetic, mechanical, and inflammatory pathogeneses ofTOLF. We provide a comprehensive evaluation of current radiological classification systems and critically appraise different decompressive procedures-ranging from classic open laminectomies to emerging minimally invasive biportal and uniportal endoscopic techniques. By assessing surgical outcomes, complications (e.g., cerebrospinal fluid leakage), and clinical indicators, this review aims to provide clinicians with an evidence-based framework for individualized surgical decision-making in managing TOLF.</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":"13 ","pages":"1896885"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13669501/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149215889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Age is the wrong axis: rethinking surgical selection for octogenarians with early-stage non-small cell lung cancer. 年龄是错误的轴:重新考虑八十多岁早期非小细胞肺癌的手术选择。
IF 1.9 4区 医学
Frontiers in Surgery Pub Date : 2026-10-01 eCollection Date: 2026-01-01 DOI: 10.3389/fsurg.2026.1961761
Vasiliki Androutsopoulou, Prokopis-Andreas Zotos, Dimitrios E Magouliotis
{"title":"Age is the wrong axis: rethinking surgical selection for octogenarians with early-stage non-small cell lung cancer.","authors":"Vasiliki Androutsopoulou, Prokopis-Andreas Zotos, Dimitrios E Magouliotis","doi":"10.3389/fsurg.2026.1961761","DOIUrl":"10.3389/fsurg.2026.1961761","url":null,"abstract":"<p><p>Lung cancer is increasingly a disease of older age, and as low-dose computed tomography screening extends into the ninth decade, a growing number of octogenarians present with early-stage, potentially curable non-small cell lung cancer. Faced with these patients, clinicians repeatedly ask a single question: is this patient too old for surgery? Recent prospective data show that selected octogenarians achieve long-term survival comparable to younger patients despite substantially higher complication rates, with quality of life that recovers over the first postoperative year. Yet the favorable result is attributed to careful selection that is rarely defined, and is seldom accompanied by any account of the patients who were assessed and not offered an operation. This article argues that chronological age is the wrong axis for the decision. Physiologic reserve, measurable through validated frailty instruments and established physiologic testing, predicts postoperative outcome far better than birth year, and aging is sufficiently heterogeneous that any age threshold misclassifies patients in both directions. A substantial competing risk of non-cancer death, compounded by overdiagnosis among screen-detected tumors, tempers the survival gain expected from aggressive treatment and makes overtreatment as real a hazard as age-based exclusion. A graded menu of options now exists, extending from minimally invasive lobectomy through sublobar resection and stereotactic ablative radiotherapy to active surveillance, and intensity should descend with reserve rather than with age. The task is to operationalize careful selection through structured geriatric assessment, multidisciplinary collaboration, prehabilitation, and shared decision-making, and to judge success by outcomes that older patients actually value.</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":"13 ","pages":"1961761"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13669174/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149215954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pseudo-cerebrospinal fluid rhinorrhea following endoscopic endonasal transsphenoidal surgery for PitNET: a case report and literature review. 经鼻内窥镜经蝶窦手术后假性脑脊液鼻漏1例报告及文献复习。
IF 1.9 4区 医学
Frontiers in Surgery Pub Date : 2026-10-01 eCollection Date: 2026-01-01 DOI: 10.3389/fsurg.2026.1945557
Guotao Peng, Jiankuai Zhou, Jun Mo
{"title":"Pseudo-cerebrospinal fluid rhinorrhea following endoscopic endonasal transsphenoidal surgery for PitNET: a case report and literature review.","authors":"Guotao Peng, Jiankuai Zhou, Jun Mo","doi":"10.3389/fsurg.2026.1945557","DOIUrl":"10.3389/fsurg.2026.1945557","url":null,"abstract":"<p><p>Pseudo-cerebrospinal fluid (CSF) rhinorrhea, defined as non-CSF nasal discharge mimicking true CSF leakage, is a rare but clinically significant complication that may prompt unnecessary aggressive treatment. We report a case of a 64-year-old man who developed positional clear nasal discharge after endoscopic endonasal resection of recurrent pituitary neuroendocrine tumor (PitNET). Glucose oxidase testing was negative, and imaging demonstrated intact skull base reconstruction. Nasal endoscopy revealed bilateral crusting and purulent secretions without evidence of CSF leak. The condition was diagnosed as vasomotor rhinitis. Conservative management-including nasal debridement, antibiotic therapy, topical corticosteroids, and saline irrigation-led to complete symptom resolution. This case underscores the importance of differentiating pseudo-CSF rhinorrhea from true CSF rhinorrhea to avoid invasive interventions.</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":"13 ","pages":"1945557"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13668825/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149215816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk factors and prediction model for post-endoscopic lithotripsy infections. 内镜下碎石术后感染的危险因素及预测模型。
IF 1.9 4区 医学
Frontiers in Surgery Pub Date : 2026-10-01 eCollection Date: 2026-01-01 DOI: 10.3389/fsurg.2026.1861286
Xiaotao Liang, Ziyong Lei, Yuxi Chen, Wei Fang, Ruming Liu, Xiaoyu Liu, Yizhe Yang, Lianhong Gao, Yongming Jiang
{"title":"Risk factors and prediction model for post-endoscopic lithotripsy infections.","authors":"Xiaotao Liang, Ziyong Lei, Yuxi Chen, Wei Fang, Ruming Liu, Xiaoyu Liu, Yizhe Yang, Lianhong Gao, Yongming Jiang","doi":"10.3389/fsurg.2026.1861286","DOIUrl":"10.3389/fsurg.2026.1861286","url":null,"abstract":"<p><strong>Objective: </strong>To identify independent risk factors for infectious complications (fever, SIRS, sepsis) after endoscopic lithotripsy and construct a multi-outcome hierarchical prediction model.</p><p><strong>Methods: </strong>Retrospective study of 914 patients (<i>n</i> = 914). Primary analysis used multinomial logistic regression for sepsis; sensitivity analysis used binary logistic regression for fever and SIRS with backward elimination. Bootstrap validation, AUC, calibration (MAE), and DCA were performed.</p><p><strong>Results: </strong>Primary analysis: positive urine culture (OR = 3.36), previous surgery (OR = 3.62), radiological signs of infection (OR = 4.02), and combined surgery (OR = 4.95) were independent risk factors for sepsis (AUC=0.794, MAE=0.008). Fever model: radiological signs and surgical modality (AUC=0.715). SIRS model: radiological signs and ULE+++ (OR = 5.1, AUC=0.73). DCA showed net clinical benefit for all three models.</p><p><strong>Conclusion: </strong>The multi-outcome hierarchical model effectively predicts postoperative infection risk. Nomograms guide individualized perioperative interventions.</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":"13 ","pages":"1861286"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13669194/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149215760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case Report: Spinoglenoid notch cysts associated with type II SLAP lesions: a report of two cases and review of the literature.
IF 1.9 4区 医学
Frontiers in Surgery Pub Date : 2026-10-01 eCollection Date: 2026-01-01 DOI: 10.3389/fsurg.2026.1792792
Jianan Ouyang, Weiming Guo, Fen Luo
{"title":"Case Report: Spinoglenoid notch cysts associated with type II SLAP lesions: a report of two cases and review of the literature.","authors":"Jianan Ouyang, Weiming Guo, Fen Luo","doi":"10.3389/fsurg.2026.1792792","DOIUrl":"https://doi.org/10.3389/fsurg.2026.1792792","url":null,"abstract":"<p><strong>Background: </strong>Spinoglenoid notch cysts associated with type II superior labrum anterior-to-posterior (SLAP) lesions are an uncommon cause of suprascapular nerve compression.</p><p><strong>Case presentation: </strong>This report presents two patients with posterior shoulder pain, weakness of inverted glenohumeral external rotation, and isolated infraspinatus atrophy. Magnetic resonance imaging confirmed spinoglenoid notch cysts communicating with type II SLAP lesions in both cases. Both patients underwent arthroscopic labral repair through standard SLAP portals, with intra-articular decompression of the cysts through the pre-existing capsular defect, avoiding additional dissection within the spinoglenoid notch. Postoperative rehabilitation and follow-up imaging demonstrated complete resolution of the cysts, restoration of infraspinatus muscle bulk, and recovery of external rotation strength.</p><p><strong>Conclusions: </strong>These cases demonstrate that arthroscopic labral repair, combined with indirect cyst decompression, can achieve complete cyst resolution and muscle recovery for selected patients. The findings support the potential reversibility of compression-related muscle atrophy following timely nerve decompression and emphasize the importance of accurate diagnosis and individualized management.</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":"13 ","pages":"1792792"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13693992/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149265809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modern hysteroscopic management of congenital uterine anomalies: current techniques, emerging technologies, and future directions. 现代宫腔镜治疗先天性子宫畸形:当前技术、新兴技术和未来方向。
IF 1.9 4区 医学
Frontiers in Surgery Pub Date : 2026-10-01 eCollection Date: 2026-01-01 DOI: 10.3389/fsurg.2026.1931279
Mariana da Cunha Vieira, Giovanna C C Martin, Katherine A R Miller, Juliana A Oliveira, Ana Clara P Servidoni, Mauricio S Abrao
{"title":"Modern hysteroscopic management of congenital uterine anomalies: current techniques, emerging technologies, and future directions.","authors":"Mariana da Cunha Vieira, Giovanna C C Martin, Katherine A R Miller, Juliana A Oliveira, Ana Clara P Servidoni, Mauricio S Abrao","doi":"10.3389/fsurg.2026.1931279","DOIUrl":"10.3389/fsurg.2026.1931279","url":null,"abstract":"<p><strong>Background: </strong>Congenital uterine anomalies are clinically relevant in reproductive medicine, particularly among women with infertility, recurrent pregnancy loss, adverse obstetric outcomes, or obstructive symptoms. Hysteroscopy has transformed the management of correctable intracavitary anomalies by enabling conservative, image-guided reconstruction of the uterine cavity while avoiding the morbidity of historical abdominal metroplasty.</p><p><strong>Scope: </strong>This narrative review critically examines contemporary hysteroscopic management of septate uterus, dysmorphic uterus, bicorporeal septate uterus and rare obstructive malformations, such as Robert's uterus. We discuss the implications of the ESHRE/ESGE, CUME, and ASRM classification systems; the role of three-dimensional transvaginal ultrasound and magnetic resonance imaging in preoperative mapping; and the technical principles that guide metroplasty, cavity remodeling, ultrasound-guided hysteroscopy, office-based metroplasty, and staged approaches in complex anatomy.</p><p><strong>Discussion: </strong>Bipolar saline-based platforms, miniaturized resectoscopes, bipolar needle electrodes, cold scissors, and selected tissue removal systems have expanded the therapeutic spectrum and improved safety. The evidence supporting surgery remains heterogeneous: the TRUST randomized trial challenged routine septum resection in unselected women, whereas data for T-shaped and other dysmorphic uteri remain largely observational. Emerging technologies, including laser platforms, artificial intelligence-assisted hysteroscopy, and robotic concepts, are promising, but currently lack prospective validation.</p><p><strong>Conclusion: </strong>Optimal management should therefore be individualized, anatomy-driven, and grounded in shared decision-making, with careful preservation of endometrium and myometrium. Standardized reporting, multicenter registries, and prospective comparative studies are needed to define which patients benefit most from hysteroscopic correction.</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":"13 ","pages":"1931279"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13669504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149215567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cross-cultural adaptation, validation, and arabic translation of the rhinoplasty outcome evaluation. 鼻整形效果评价的跨文化适应、验证和阿拉伯语翻译。
IF 1.9 4区 医学
Frontiers in Surgery Pub Date : 2026-09-30 eCollection Date: 2026-01-01 DOI: 10.3389/fsurg.2026.1744891
Feras Alkholaiwi, Yazeed Alghonaim
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