Frontiers in Surgery最新文献

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Single-incision laparoscopic cholecystectomy reduced postoperative pain than three-incision laparoscopic cholecystectomy in patients with large gallstone, a retrospective study.
IF 1.6 4区 医学
Frontiers in Surgery Pub Date : 2024-12-05 eCollection Date: 2024-01-01 DOI: 10.3389/fsurg.2024.1448684
Zhiheng Zhang, Jiawei Xu, Decai Yu, Nacheng Lin, Jin Peng
{"title":"Single-incision laparoscopic cholecystectomy reduced postoperative pain than three-incision laparoscopic cholecystectomy in patients with large gallstone, a retrospective study.","authors":"Zhiheng Zhang, Jiawei Xu, Decai Yu, Nacheng Lin, Jin Peng","doi":"10.3389/fsurg.2024.1448684","DOIUrl":"https://doi.org/10.3389/fsurg.2024.1448684","url":null,"abstract":"<p><strong>Aim: </strong>To compare the short-term outcomes between SILC and TILC depending on gallstone size.</p><p><strong>Material and methods: </strong>Data from 114 patients with gallstones who underwent cholecystectomy hospitalized in Nanjing Drum Tower Hospital between June 2022 and October 2023 were collected. The gallstone diameter, the operation time, estimated blood loss, post-operative pain, complications post-operation, and length of hospital stay were all collected and examined.</p><p><strong>Results: </strong>Of the 114 patients included in this study, 61 underwent SILC, and 53 underwent TILC. The pain score 6 h, 24 h post-operation was higher in the TILC group compared with the SILC group. Patients were divided into large (diameter > 2 cm) and small groups (diameter < 2 cm), larger gallstones significantly increased operation duration in the SILC group. For the TILC group, large gallstones significantly increased blood loss during the operation. The blood loss and pain scores were higher in the TILC group compared with the SILC group for patients with large gallstones.</p><p><strong>Conclusion: </strong>In this study, SILC and TILC both had comparable postoperative outcomes, while SILC significantly reduced postoperative pain than TILC. Moreover, SILC might be a suitable option for patients with larger gallstones (diameter > 2 cm) and helps reduce blood loss and postoperative pain.</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":"11 ","pages":"1448684"},"PeriodicalIF":1.6,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11655490/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case Report: Treatment of a complex hand disfigurement injury by fully shaped reconstruction of a severed finger combined with ectopic banking. 病例报告:通过断指全形再造结合异位银行治疗复杂的手部毁容伤。
IF 1.6 4区 医学
Frontiers in Surgery Pub Date : 2024-12-05 eCollection Date: 2024-01-01 DOI: 10.3389/fsurg.2024.1488338
Zhengfeng Jia, Longbao Shi, Weilu Gao, Han Li, Jianzheng Zhang, Weidong Shi, Jiantao Li, Jianwen Zhao
{"title":"Case Report: Treatment of a complex hand disfigurement injury by fully shaped reconstruction of a severed finger combined with ectopic banking.","authors":"Zhengfeng Jia, Longbao Shi, Weilu Gao, Han Li, Jianzheng Zhang, Weidong Shi, Jiantao Li, Jianwen Zhao","doi":"10.3389/fsurg.2024.1488338","DOIUrl":"https://doi.org/10.3389/fsurg.2024.1488338","url":null,"abstract":"<p><p>One of the primary challenges in hand microsurgical reconstruction lies in addressing severe hand injuries, particularly those involving multiple finger amputations, as autologous replantation might not fully restore hand functionality. In such scenarios, fully shaped reconstruction of a severed finger combined with Ectopic banking could yield superior reconstructive outcomes and enhance the amputated limb's function. This case report presents a unique approach that combines ectopic replantation of an amputated finger with interphalangeal reconstruction methods to restore both the form and function of the hand. A 43-year-old female patient suffered an injury to her left hand, leading to ischaemic amputation of all four fingers. Our treatment strategy involved a blend of allograft reimplantation, interdigital reconstruction, iliac bone grafting, and metacarpophalangeal joint fusion to revive the hand's functionality. A year post-surgery, the toe-to-finger reconstructions of the left thumb and middle finger exhibited excellent survival, although the ring and little fingers were lost. The flap located on the dorsum of the left foot healed seamlessly, with uninterrupted blood flow to the toe tips and no complications. As a result, the patient retained three fingers and regained functional activity. Our study underscores that the synergistic approach of fully shaped reconstruction of a severed finger combined with Ectopic banking not only elevates surgical efficiency but also significantly bolsters hand morphology and function. This case report underscores the significance of the Treatment of a complex hand disfigurement injury by fully shaped reconstruction of a severed finger combined with Ectopic banking in the realm of finger reconstruction, highlighting their transformative potential in restoring hand function and appearance.</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":"11 ","pages":"1488338"},"PeriodicalIF":1.6,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11656348/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Choosing the proper path: outcomes of subxiphoid vs. lateral intercostal approaches in the resection of anterior mediastinal masses. 选择合适的路径:剑突下与肋间外侧入路切除前纵隔肿块的效果。
IF 1.6 4区 医学
Frontiers in Surgery Pub Date : 2024-12-03 eCollection Date: 2024-01-01 DOI: 10.3389/fsurg.2024.1463881
Xuechun Leng, Mengzou Chen, Yang Zhang, Jian Gao, Zhenbing You, Zhongwu Hu
{"title":"Choosing the proper path: outcomes of subxiphoid vs. lateral intercostal approaches in the resection of anterior mediastinal masses.","authors":"Xuechun Leng, Mengzou Chen, Yang Zhang, Jian Gao, Zhenbing You, Zhongwu Hu","doi":"10.3389/fsurg.2024.1463881","DOIUrl":"https://doi.org/10.3389/fsurg.2024.1463881","url":null,"abstract":"<p><strong>Background: </strong>While the subxiphoid approach (SA) in thoracoscopic thymectomy offers benefits in terms of fat removal and pain reduction, it remains unclear which patients with anterior mediastinal masses benefit most from the subxiphoid vs. the lateral intercostal approach (LA).</p><p><strong>Methods: </strong>This retrospective study analyzed patients treated for anterior mediastinal masses at our center from January 2019 to December 2023. Patients were categorized into two groups based on the surgical approach: SA (35 cases) and LA (56 cases). Demographic data, clinical characteristics, perioperative metrics, and short-term outcomes were compared.</p><p><strong>Results: </strong>Ninety-one patients were included, with diagnoses including thymic cysts (43), thymomas types A, AB, and B1 (24), B2 thymomas (18), thymic carcinoma (6).No significant differences were found between the groups in terms of gender, age, tumor size, body mass index, conversion to sternotomy, or blood loss. The LA group, however, experienced shorter surgical durations (<i>P</i> < 0.001), less drainage (<i>P</i> = 0.021), shorter hospital stays (<i>P</i> < 0.001), and lower hospitalization costs (<i>P</i> = 0.024). Pain scores on the visual analogue scale were similar between groups on the day of surgery and the first postoperative day.</p><p><strong>Conclusion: </strong>The findings suggest that the lateral intercostal approach is preferable for patients with thymic cysts and Masaoka stage I-II thymomas without myasthenia gravis due to its efficiency and cost-effectiveness.</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":"11 ","pages":"1463881"},"PeriodicalIF":1.6,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11649629/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142846261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of blunt splenic injury in children in China.
IF 1.6 4区 医学
Frontiers in Surgery Pub Date : 2024-12-03 eCollection Date: 2024-01-01 DOI: 10.3389/fsurg.2024.1502557
Wu Wang, Haiyan Lei, Wenhan Zhang, Wenhai Li, Hongqiang Bian, Jun Yang
{"title":"Treatment of blunt splenic injury in children in China.","authors":"Wu Wang, Haiyan Lei, Wenhan Zhang, Wenhai Li, Hongqiang Bian, Jun Yang","doi":"10.3389/fsurg.2024.1502557","DOIUrl":"https://doi.org/10.3389/fsurg.2024.1502557","url":null,"abstract":"<p><strong>Introduction: </strong>Nonoperative management (NOM) is recognized as a viable treatment for pediatric closed splenic trauma. However, clinical guidelines are applied inconsistently, resulting in different treatment strategies in different regions. This study aimed to investigate the independent risk factors influencing the length of stay in pediatric closed splenic injuries and to analyze the key determinants in the choice of surgical treatment to optimize inpatient management and patient care and improve outcomes.</p><p><strong>Methods: </strong>A retrospective evaluation of medical records of pediatric patients with blunt splenic injury (BSI) admitted to Wuhan Children's Hospital from 2020 to 2024 was conducted. The dataset included demographics, mechanism of injury, injury grade, associated injuries, therapeutic measures, and outcomes, which were subjected to statistical analysis. Factors influencing length of hospital stay and treatment regimen were also analyzed.</p><p><strong>Results: </strong>A total of 88.5% of patients underwent NOM, with 11% requiring splenic embolization due to hemodynamic instability or arterial hemorrhage. Surgery was required in 11.5% of patients, primarily for combined gastrointestinal perforation, or peritonitis. One patient died due to brain injury. Trauma scores and transfusion requirements were higher in the surgical group (37.7 ± 16.1 vs. 17.2 ± 13.1, <i>p</i> < 0.001; 21.7% vs. 100%, <i>p</i> < 0.001). Multivariate logistic regression showed that gastrointestinal complications significantly influenced the decision to operate (<i>p</i> = 0.0087). A generalized additive model showed a corresponding increase in length of stay with increasing injury severity, with the curve flattening in the mid to high ISS range (40-60).</p><p><strong>Conclusion: </strong>NOM remains an effective and preferred treatment strategy for pediatric BSI, particularly in the setting of stable hemodynamic parameters. This approach reduces the need for surgical intervention and associated complications while preserving splenic function. The study highlights that gastrointestinal complications are important determinants of surgical management. Further research into long-term outcomes and advancements in conservative management are needed.</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":"11 ","pages":"1502557"},"PeriodicalIF":1.6,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11649639/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142846313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cystic plate approach in laparoscopic cholecystectomy: a consecutive retrospective analysis.
IF 1.6 4区 医学
Frontiers in Surgery Pub Date : 2024-12-03 eCollection Date: 2024-01-01 DOI: 10.3389/fsurg.2024.1487568
Yanjie Zhou, Le Xiao, Zhulin Luo, Hao Luo, Zhen Tan, Tao Wang
{"title":"Cystic plate approach in laparoscopic cholecystectomy: a consecutive retrospective analysis.","authors":"Yanjie Zhou, Le Xiao, Zhulin Luo, Hao Luo, Zhen Tan, Tao Wang","doi":"10.3389/fsurg.2024.1487568","DOIUrl":"https://doi.org/10.3389/fsurg.2024.1487568","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to investigate the safety, feasibility, and possible advantages of the cystic plate approach during laparoscopic cholecystectomy in a retrospective cohort of surgical patients.</p><p><strong>Methods: </strong>We summarized the key points of the technical approach, retrospectively analyzed the clinical outcomes of 156 patients in the cystic plate approach group from July 2018 to July 2023, and compared the findings with those of 173 cases in the routine approach group from the same period.</p><p><strong>Results: </strong>We observed no differences in the average stone size, operation time, postoperative hospital stay, conversion rate, complications, or Visual Analog Scale pain scores on the second day of surgery between the two groups (<i>p</i> = 0.076, 0.067, 0.278, 1.000, 0.633, and 0.131, respectively). However, intraoperative blood loss, number of clips used, volume of postoperative drainage fluid, and Visual Analog Scale pain scores on the day of surgery in the cystic plate approach group were significantly lower than those in the routine approach group (<i>p</i> = 0.000, 0.031, 0.027, and 0.021, respectively).</p><p><strong>Conclusions: </strong>The cystic plate approach is a safe, feasible, and effective approach that has the advantages of minimal invasiveness with less bleeding and seepage, reduced use of biological clips, and less pain, potentially minimizing the risk of iatrogenic biliary injury.</p><p><strong>Trial registration: </strong>This study was registered at the International Clinical Trial Registry (ChiCTR2100052860). Registration date: November 6, 2021.</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":"11 ","pages":"1487568"},"PeriodicalIF":1.6,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11649668/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142846304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial: Translational research in surgical applications and spinal tumors.
IF 1.6 4区 医学
Frontiers in Surgery Pub Date : 2024-12-03 eCollection Date: 2024-01-01 DOI: 10.3389/fsurg.2024.1492713
Madison J Michles, Margot Martinez Moreno, Patricia L Zadnik Sullivan, Ziya L Gokaslan
{"title":"Editorial: Translational research in surgical applications and spinal tumors.","authors":"Madison J Michles, Margot Martinez Moreno, Patricia L Zadnik Sullivan, Ziya L Gokaslan","doi":"10.3389/fsurg.2024.1492713","DOIUrl":"https://doi.org/10.3389/fsurg.2024.1492713","url":null,"abstract":"","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":"11 ","pages":"1492713"},"PeriodicalIF":1.6,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11649541/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142846306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictors of mortality at 3 months in patients with skull base tumor resections in a low-income setting.
IF 1.6 4区 医学
Frontiers in Surgery Pub Date : 2024-12-03 eCollection Date: 2024-01-01 DOI: 10.3389/fsurg.2024.1398829
Mestet Yibeltal Shiferaw, Abat Sahlu Baleh, Abel Gizaw, Tsegazeab Laeke Teklemariam, Abenezer Tirsit Aklilu, Atalel Fentahun Awedew, Denekew Tenaw Anley, Bereket Hailu Mekuria, Ermias Fikiru Yesuf, Mengistu Ayele Yigzaw, Henok Teshome Molla, Mekides Muse Awano, Alemu Adise Mldie, Endeshaw Chekole Abebe, Nebyou Hailu, Sura Daniel, Dejen Teke Gebrewahd
{"title":"Predictors of mortality at 3 months in patients with skull base tumor resections in a low-income setting.","authors":"Mestet Yibeltal Shiferaw, Abat Sahlu Baleh, Abel Gizaw, Tsegazeab Laeke Teklemariam, Abenezer Tirsit Aklilu, Atalel Fentahun Awedew, Denekew Tenaw Anley, Bereket Hailu Mekuria, Ermias Fikiru Yesuf, Mengistu Ayele Yigzaw, Henok Teshome Molla, Mekides Muse Awano, Alemu Adise Mldie, Endeshaw Chekole Abebe, Nebyou Hailu, Sura Daniel, Dejen Teke Gebrewahd","doi":"10.3389/fsurg.2024.1398829","DOIUrl":"https://doi.org/10.3389/fsurg.2024.1398829","url":null,"abstract":"<p><strong>Objective: </strong>Globally, skull base tumors are among the most challenging tumors to treat and are known for their significant morbidity and mortality. Hence, this study aimed to identify robust associated factors that contribute to mortality of patients following surgical resection for a variety of skull base tumors at the 3-month follow-up period. This in turn helps devise an evidence-based meticulous treatment strategy and baseline input for quality improvement work.</p><p><strong>Methodology: </strong>A retrospective cohort study of patients undergoing skull base tumor resection was conducted at two large-volume neurosurgery centers in Ethiopia. The categorical variables were expressed in frequencies and percentages. Normal distribution of continuous data was checked by histogram and the Shapiro-Wilk test. Median with interquartile range (IQR) was calculated for skewed data, while mean with standard deviation (SD) was used for normally distributed data. Odds ratio and adjusted odds ratio (AOR) were used to express the result of univariate and multivariate binary logistic analyses, respectively. A <i>p</i>-value <0.005 was considered statistically significant at 95% confidence interval (CI).</p><p><strong>Result: </strong>The study involved 266 patients. Of this, women accounted for 63.5% of patients. The median age of patients was 37 (±IQR = 17) years while the median size of the tumor in this study was 4.9 (±IQR 1.5) cm. The mean duration of symptoms at time of presentation was 17.3 (±SD = 11.1) months. Meningioma, pituitary adenoma, and craniopharyngioma contributed to 68.4%, 19.2%, and 9% of the skull-based tumors, respectively. Mortality following skull base tumor resection was 21.1%. On multivariable binary logistic regression analysis, intraoperative iatrogenic vascular insult (AOR = 28.76, 95% CI: 6.12-135.08, <i>p</i> = 0.000), intraventricular hemorrhage (AOR = 6.32, 95% CI: 1.19-33.63, <i>p</i> = 0.031), hospital-associated infection (AOR = 6.96, 95% CI: 2.04-23.67, <i>p</i> = 0.002), and extubation time exceeding 24 h (AOR = 12.89, 95% CI: 4.89-40.34, <i>p</i> = 0.000) were statistically significant with 3-month mortality.</p><p><strong>Conclusion: </strong>Mortality from skull base tumor resection remains high in our setting. Holistic pre-operative surgical planning, meticulous intraoperative execution of procedures, and post-operative dedicated follow-up of patients in a neurointensive care unit alongside quality improvement works on identified risks of mortality are strongly recommended to improve patient outcomes. The urgent need for setup improvement and further training of neurosurgeons is also underscored.</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":"11 ","pages":"1398829"},"PeriodicalIF":1.6,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11653179/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142853591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case Report: A young man with frontal traumatic sinus pericranii.
IF 1.6 4区 医学
Frontiers in Surgery Pub Date : 2024-12-03 eCollection Date: 2024-01-01 DOI: 10.3389/fsurg.2024.1479233
Zihao Zhang, Qingpei Hao, Ruirui Luan, Guangbiao Qin, Ruen Liu
{"title":"Case Report: A young man with frontal traumatic sinus pericranii.","authors":"Zihao Zhang, Qingpei Hao, Ruirui Luan, Guangbiao Qin, Ruen Liu","doi":"10.3389/fsurg.2024.1479233","DOIUrl":"https://doi.org/10.3389/fsurg.2024.1479233","url":null,"abstract":"<p><p>Sinus pericranii is a rare venous anomaly characterized by abnormal communication between intracranial and subperiosteal veins, and reports of trauma-induced sinus pericranii are even rarer. Herein, we report a case of delayed-onset sinus pericranii resulting from a traumatic injury to the left side of the midline of the forehead sustained in early childhood. The anomaly was successfully resected via a coronal incision within the hairline, followed by meticulous bone wax sealing. In this paper, we aim to provide details on the diagnosis and surgical techniques of trauma-induced sinus pericranii, contributing valuable insights for the management of such rare condition.</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":"11 ","pages":"1479233"},"PeriodicalIF":1.6,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11649643/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142846221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Platelet rich fibrin three-layer reconstruction of the sellar floor after endoscopic endonasal transsphenoidal approach: technical note and initial experience.
IF 1.6 4区 医学
Frontiers in Surgery Pub Date : 2024-12-03 eCollection Date: 2024-01-01 DOI: 10.3389/fsurg.2024.1500158
Mukesch Johannes Shah, Katerina Argiti, Julia M Nakagawa, Angeliki Stathi, Emilia Schönen, Daniel Strahnen, Kevin Joseph, Jakob Straehle, Nicolas Neidert, Jürgen Beck, Ioannis Vasilikos
{"title":"Platelet rich fibrin three-layer reconstruction of the sellar floor after endoscopic endonasal transsphenoidal approach: technical note and initial experience.","authors":"Mukesch Johannes Shah, Katerina Argiti, Julia M Nakagawa, Angeliki Stathi, Emilia Schönen, Daniel Strahnen, Kevin Joseph, Jakob Straehle, Nicolas Neidert, Jürgen Beck, Ioannis Vasilikos","doi":"10.3389/fsurg.2024.1500158","DOIUrl":"https://doi.org/10.3389/fsurg.2024.1500158","url":null,"abstract":"<p><strong>Background: </strong>Cerebrospinal fluid (CSF) leakage frequently complicates endoscopic endonasal transsphenoidal pituitary resections, despite the use of lumbar drains, nasoseptal flaps, or commercial dura sealants. Managing this complication often requires revision surgery and increases the risk of infection. Platelet-rich fibrin (PRF), an affordable autologous biomaterial derived from the patient's blood through short, angulated centrifugation, contains growth factors and leukocytes embedded in a fibrin matrix. PRF exhibits regenerative properties in various surgical disciplines. This study assesses a three-layer sellar reconstruction method employing solid membranous (s-PRF) and high-viscosity injectable (i-PRF) forms of PRF.</p><p><strong>Materials and methods: </strong>We present our initial experience on a series of 22 patients with pituitary macroadenomas. For all patients, an endoscopic transnasal transsphenoidal approach was selected. Following the resection of the pathology, sellar reconstruction was accomplished using a three-layer orthobiologic technique. A membranous s-PRF was utilized as an inlay inside the opened sellar floor, followed by a layer of injectable i-PRF finally covered with another s-PRF membrane over the top to the sellar corridor.</p><p><strong>Results: </strong>In all cases the implementation of the proposed three-layer PRF reconstruction strategy was feasible and safe. During the 12-month follow-up period there were no adverse effects reported associated with the PRF application. 77% (17/22) of the patients demonstrated intraoperatively a cerebrospinal fluid (CSF) leak (Esposito Grade 1-3). In total, the proposed PRF reconstruction effectively prevented postoperative CSF leaks in 95% of the patients and in 94% of those with an Esposito Grade 1-3. One of the two patients with intraoperative Esposito Grade 3 developed a CSF leak on the first postoperative day, which was successfully managed with a lumbar drain for 5 days.</p><p><strong>Conclusion: </strong>Sellar reconstruction after endoscopic endonasal transsphenoidal resection of pituitary adenomas with PRF is feasible and safe. The three layer PRF augmentation is a novel technique to prevent CSF-leakage.</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":"11 ","pages":"1500158"},"PeriodicalIF":1.6,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11649627/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142846308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Challenges following CRS and HIPEC surgery in cancer patients with peritoneal metastasis: a comprehensive review of clinical outcomes. 腹膜转移癌症患者接受 CRS 和 HIPEC 手术后面临的挑战:临床结果综合评述。
IF 1.6 4区 医学
Frontiers in Surgery Pub Date : 2024-12-02 eCollection Date: 2024-01-01 DOI: 10.3389/fsurg.2024.1498529
Mehdi Karimi, Niyousha Shirsalimi, Eshagh Sedighi
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