Fungal Biology Reviews最新文献

Ecological roles of leaf-inhabiting fungi and their host-associated predictors: a review 叶栖真菌的生态作用及其与寄主相关的预测因子综述

IF 4.6 2区生物学

Fungal Biology Reviews Pub Date : 2026-03-01 Epub Date: 2026-02-17 DOI: 10.1016/j.fbr.2026.100475

Hajra Khalil , Leho Tedersoo , Niloufar Hagh-Doust

{"title":"Ecological roles of leaf-inhabiting fungi and their host-associated predictors: a review","authors":"Hajra Khalil , Leho Tedersoo , Niloufar Hagh-Doust","doi":"10.1016/j.fbr.2026.100475","DOIUrl":"10.1016/j.fbr.2026.100475","url":null,"abstract":"<div><div>Plant microbiome refers to the diverse communities of microorganisms, including bacteria, fungi, viruses, and archaea, that inhabit plant organs and surfaces. Plant microbiomes contribute to nutrient acquisition, plant immunity, stress resilience, and overall plant fitness. Among these microorganisms, leaf-associated fungi, encompassing saprotrophic, endophytic, and pathogenic species, play essential roles in plant and ecosystem functioning. This review provides an overview of the current knowledge on the functional roles of leaf-associated fungi and how plant functional traits and host identity shape these fungal communities. The functional identity of many fungi is dynamic, shaped by ecological plasticity that allows shifts in lifestyle across temporal and spatial gradients. Our synthesis highlights that plant structural, chemical, and phenological traits expressed within species-specific evolutionary contexts act as ecological filters influencing fungal colonization, community composition, and functional strategies. Thus, the ecological roles of leaf-associated fungi emerge from the interaction among plant phenotype, host identity, and environmental conditions. Future studies should utilize culture-dependent and culture-independent approaches to fully uncover the ecological roles and diversity of leaf-associated fungi. Such studies will provide valuable insights for conservation and sustainable ecosystem management amidst global environmental changes.</div></div>","PeriodicalId":12563,"journal":{"name":"Fungal Biology Reviews","volume":"55 ","pages":"Article 100475"},"PeriodicalIF":4.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147421084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Arbuscular mycorrhizal fungi in desert ecosystems: Adaptive mechanisms to co-occurring drought, temperature, and salinity stress 沙漠生态系统中的丛枝菌根真菌：对同时发生的干旱、温度和盐度胁迫的适应机制

IF 4.6 2区生物学

Fungal Biology Reviews Pub Date : 2026-03-01 Epub Date: 2026-01-31 DOI: 10.1016/j.fbr.2026.100472

Hassan Etesami , Umarov Otabek , Bafayeva Zahro , Yuldoshov Laziz , Nazarova Sevara

{"title":"Arbuscular mycorrhizal fungi in desert ecosystems: Adaptive mechanisms to co-occurring drought, temperature, and salinity stress","authors":"Hassan Etesami , Umarov Otabek , Bafayeva Zahro , Yuldoshov Laziz , Nazarova Sevara","doi":"10.1016/j.fbr.2026.100472","DOIUrl":"10.1016/j.fbr.2026.100472","url":null,"abstract":"<div><div>Arid ecosystems, covering over 40 % of Earth's land, face increasing stress from drought, salinity, and extreme temperatures. Arbuscular mycorrhizal fungi (AMF) form keystone symbioses with desert plants, enhancing their resilience to these co-occurring stressors. This review synthesizes mechanistic and field-based evidence from deserts (e.g., Caatinga, Atacama, and Arabian Peninsula), showing AMF mediate drought tolerance through osmotic adjustment and improved water/nutrient uptake via extensive hyphal networks. In saline conditions, AMF enhance ion homeostasis, reducing Na<sup>+</sup> toxicity. Key mechanisms include activation of antioxidant defense systems (e.g., superoxide dismutase, catalase, and ascorbate peroxidase) and modulation of phytohormones (e.g., abscisic acid) and stress-responsive genes (e.g., aquaporins). Morphological adaptations like improved soil aggregation via glomalin-related soil proteins further aid water retention. However, benefits are context-dependent, varying with fungal and host identity, and can be absent under hyper-arid extremes. Field studies confirm native AMF communities, particularly Glomeraceae, are critically adapted for local stress tolerance and are vital for soil health and combating desertification. Their functionality declines at environmental thresholds, underscoring the need to conserve indigenous symbionts. Future research must prioritize multi-stress interactions, molecular cross-talk in tripartite symbioses (e.g., AMF-endobacteria-plant), and developing climate-resilient AMF inoculants for restoration. Integrating omics with field studies will elucidate microbial consortia dynamics, advancing sustainable agriculture in arid frontiers and advocating for AMF-centric approaches to preserve biodiversity in a warming climate.</div></div>","PeriodicalId":12563,"journal":{"name":"Fungal Biology Reviews","volume":"55 ","pages":"Article 100472"},"PeriodicalIF":4.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146090706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Omics approaches in Cryptococcosis: Molecular insights into host alterations 隐球菌病的组学方法：宿主改变的分子洞察

IF 4.6 2区生物学

Fungal Biology Reviews Pub Date : 2026-03-01 Epub Date: 2026-02-13 DOI: 10.1016/j.fbr.2026.100473

Laura Rascovetzki Saciloto-de-Oliveira , Yohana Porto Calegari-Alves , Júlia de Fraga Sant’Ana , Camila Innocente-Alves , Anna Karoline Canelossi Valério , Marilene Henning Vainstein , Lucélia Santi , Walter Orlando Beys-da-Silva

{"title":"Omics approaches in Cryptococcosis: Molecular insights into host alterations","authors":"Laura Rascovetzki Saciloto-de-Oliveira , Yohana Porto Calegari-Alves , Júlia de Fraga Sant’Ana , Camila Innocente-Alves , Anna Karoline Canelossi Valério , Marilene Henning Vainstein , Lucélia Santi , Walter Orlando Beys-da-Silva","doi":"10.1016/j.fbr.2026.100473","DOIUrl":"10.1016/j.fbr.2026.100473","url":null,"abstract":"<div><div>Cryptococcosis is one of the most common invasive fungal diseases in immunocompromised subjects, and it is associated with a high mortality rate. This disease is caused by fungi of the <em>Cryptococcus</em> genus, particularly by members of the <em>Cryptococcus neoformans</em> and <em>Cryptococcus gattii</em> species complex. The infection typically originates in the lungs and can spread to the central nervous system and other organs, often resulting in cryptococcal meningitis, a serious and potentially fatal condition. Understanding molecular pathogenesis is essential for paving the way for more accurate diagnoses and effective treatments, ultimately improving clinical outcomes. In this regard, omics approaches are a valuable tool to help elucidate infection alterations. Indeed, several studies have employed these approaches, mostly focusing on fungal molecular changes, while fewer articles address host molecular changes. This review provides an overview of the molecular aspects of cryptococcosis, emphasizing the contributions of omics sciences to infection characterization toward host impact. Accordingly, this article offers new insights into this infectious disease, such as modulation of the host immune system and alterations in energy metabolism. Additionally, we highlight the versatility of omics science in addressing different infection characterization approaches using several experimental models, including cell cultures, from immune systems to epithelial cells and <em>in vivo</em> models.</div></div>","PeriodicalId":12563,"journal":{"name":"Fungal Biology Reviews","volume":"55 ","pages":"Article 100473"},"PeriodicalIF":4.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147421083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dematophora necatrix: From taxonomy to molecular advances 颈线虫：从分类到分子进展

IF 4.6 2区生物学

Fungal Biology Reviews Pub Date : 2026-03-01 Epub Date: 2026-01-19 DOI: 10.1016/j.fbr.2026.100471

Maryke Carstens , Clara Pliego , Annabel Norval , Noëlani van den Berg

{"title":"Dematophora necatrix: From taxonomy to molecular advances","authors":"Maryke Carstens , Clara Pliego , Annabel Norval , Noëlani van den Berg","doi":"10.1016/j.fbr.2026.100471","DOIUrl":"10.1016/j.fbr.2026.100471","url":null,"abstract":"<div><div><em>Dematophora necatrix</em> Hartig is a destructive soil-borne fungus responsible for White Root Rot (WRR), affecting more than 350 plant species across 51 countries, including many economically important crops. The pathogen's persistence in soil and broad host range makes it especially challenging to control. Over the past decade, molecular studies have significantly advanced our understanding of the pathogen's biology and its interactions with host plants. These developments underscore the need for a comprehensive review to consolidate recent scientific progress. First, we outline the taxonomy, biology, disease symptoms, hosts and global distribution, and current management strategies of <em>D. necatrix</em>. We then focus on recent molecular advances, highlighting how genomics, transcriptomics, proteomics and metabolomics studies have improved our understanding of the pathogen's virulence and pathogenicity. A high-quality, chromosome-level genome assembly has enabled more precise annotation and gene prediction. Transcriptomic analyses have identified candidate pathogenicity-related genes and putative effectors, while secretome proteomic studies suggest the production of antimicrobial proteins which may facilitate infection by suppressing microbial competitors. Secondary metabolites, such as cytochalasin E, have been implicated in virulence, although their precise roles in pathogenicity remain unresolved. Improved transformation protocols now permit targeted gene manipulation, creating new opportunities for functional studies. Lastly, this review highlights key knowledge gaps and calls for integrated multi-omics approaches to better understand <em>D. necatrix</em> pathogenicity and virulence, long-term survival, and environmental adaptation. Such insights are critical for the development of durable, targeted strategies to manage WRR.</div></div>","PeriodicalId":12563,"journal":{"name":"Fungal Biology Reviews","volume":"55 ","pages":"Article 100471"},"PeriodicalIF":4.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146034636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Do we need a more structured system for gene names and pathways now that omics studies revealed a higher complexity of fungal carbon metabolism? 既然组学研究揭示了真菌碳代谢的更高复杂性，我们是否需要一个更结构化的基因名称和途径系统？

IF 4.6 2区生物学

Fungal Biology Reviews Pub Date : 2026-03-01 Epub Date: 2025-12-29 DOI: 10.1016/j.fbr.2025.100470

Ronald P. de Vries, Jiajia Li

{"title":"Do we need a more structured system for gene names and pathways now that omics studies revealed a higher complexity of fungal carbon metabolism?","authors":"Ronald P. de Vries, Jiajia Li","doi":"10.1016/j.fbr.2025.100470","DOIUrl":"10.1016/j.fbr.2025.100470","url":null,"abstract":"<div><div>Omics studies have revealed a much higher complexity and diversity of fungal primary carbon metabolism than was previously assumed, especially with respect to the number of genes/enzymes involved in individual pathway steps. These new insights sometimes conflict with historical gene naming systems which may lead to confusion, especially in comparative studies with multiple fungi. To reduce such issues in the future, especially taking into account the increasing use of AI-methods in data mining and comparative genomics, a more systematic and uniform naming system could be beneficial. This would require some gene renaming and prevention of using different names for the same biological function or the same name for genes with different biological functions and likely will depend on a fungal community-wide effort to achieve this. In this opinion paper we suggest such a structure, based on the genes involved in primary carbon metabolism of one of the best studied fungi in this field, the ascomycete <em>Aspergillus niger</em>. The proposed restructuring in this opinion paper therefore represents a model-derived framework rather than a universally applicable solution.</div></div>","PeriodicalId":12563,"journal":{"name":"Fungal Biology Reviews","volume":"55 ","pages":"Article 100470"},"PeriodicalIF":4.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145880664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mechanisms of chronic infection: The multificated strategy of Cryptococcus 慢性感染的机制：隐球菌的多重策略

IF 4.6 2区生物学

Fungal Biology Reviews Pub Date : 2026-03-01 Epub Date: 2025-12-10 DOI: 10.1016/j.fbr.2025.100469

Sijie Qian, Danfeng Fang, Hongxin Fu, Wei Wu, Weibo Du

引用次数: 0

Rhodotorula genus: vast knowledge, limited commercialization – What's holding us back? 红酵母属：广博的知识，有限的商业化——是什么阻碍了我们？

IF 4.6 2区生物学

Fungal Biology Reviews Pub Date : 2025-12-01 Epub Date: 2025-10-16 DOI: 10.1016/j.fbr.2025.100459

Imene Chentir , Yamina Ben Miri , Anna Maria Kot , Pooja Nikhanj , Cassamo Ussemane Mussagy , Fatma Arous , Giorgos Markou

引用次数: 0

Opening the black box of an underexplored and megadiverse group: history, taxonomy and functionality of dark septate endophytes (DSE) 打开一个未被充分探索和多样化的群体的黑盒子：暗隔内生菌（DSE）的历史、分类和功能

IF 4.6 2区生物学

Fungal Biology Reviews Pub Date : 2025-12-01 Epub Date: 2025-09-12 DOI: 10.1016/j.fbr.2025.100457

Jaqueline Aparecida de Oliveira, Olinto Liparini Pereira

{"title":"Opening the black box of an underexplored and megadiverse group: history, taxonomy and functionality of dark septate endophytes (DSE)","authors":"Jaqueline Aparecida de Oliveira, Olinto Liparini Pereira","doi":"10.1016/j.fbr.2025.100457","DOIUrl":"10.1016/j.fbr.2025.100457","url":null,"abstract":"<div><div>Dark septate endophytes (DSE) are facultative, biotrophic fungi that have a close association with and are restricted to plant roots; typically, with darkly-pigmented hyphae, and which frequently produce microsclerotia within the host tissues. They do not form a single taxonomic category and are distributed across different classes, orders and families of the phylum <em>Ascomycota</em>, representing a highly taxonomically-diverse group. There has been greater emphasis on studying DSE that can resist abiotic stresses and which confer this ability to their host plants such as resistance to high concentrations of salts and heavy metals; conditions of low nutrient availability; and, periods of prolonged drought. Furthermore, it has been demonstrated that DSE have the potential to improve the performance of many crops, as evidenced by <em>in vitro</em> studies. The first observations of DSE date back over a century but, only recently, have studies focused exclusively on understanding this unique group of fungi, especially their taxonomy and functionality. This review provides a detailed history of DSE and highlights the many challenges posed by studying them. We also aim to encourage more in-depth and multidisciplinary research on DSE, particularly due to the urgent need for innovative and sustainable technologies in agriculture. DSE have shown great potential as candidates for developing future ‘bioinputs’ or ‘biologicals’.</div></div>","PeriodicalId":12563,"journal":{"name":"Fungal Biology Reviews","volume":"54 ","pages":"Article 100457"},"PeriodicalIF":4.6,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145045011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial: Together we raise the mycologists of the future 社论：我们一起培养未来的真菌学家

IF 4.6 2区生物学

Fungal Biology Reviews Pub Date : 2025-12-01 Epub Date: 2025-11-14 DOI: 10.1016/j.fbr.2025.100460

Jan Dijksterhuis (Senior Editor), Irina S. Druzhinina (Senior Editor)

引用次数: 0

Fungi-mediated nanomaterials: Advances, synthesis pathways, and limitations 真菌介导的纳米材料：进展、合成途径和局限性

IF 4.6 2区生物学

Fungal Biology Reviews Pub Date : 2025-12-01 Epub Date: 2025-08-15 DOI: 10.1016/j.fbr.2025.100445

Parikshana Mathur, Santhosh Pillai

引用次数: 0