{"title":"Features of sarcopenic obesity in rheumatoid arthritis patients","authors":"Yuma Saito, Mochihito Suzuki, Toshihisa Kojima, Hiroto Yamamoto, Yuki Saito, Kenya Terabe, Yoshifumi Ohashi, Ryo Sato, Junya Hasegawa, Yusuke Ohno, Kaoru Nagai, Chinami Ohnishi, Hideshi Sugiura, Hitomi Fujita, Mako Nagayoshi, Masayo Kojima, Shuji Asai, Shiro Imagama","doi":"10.1111/ggi.70149","DOIUrl":"10.1111/ggi.70149","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>The present study aimed to determine the proportion of rheumatoid arthritis (RA) patients with sarcopenic obesity and to identify associated factors through assessments of physical function and patient-reported outcomes (PROs).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A prospective cohort study of 321 RA patients aged 40–79 years was conducted. Participants were classified into four groups—Normal, Obesity, Sarcopenia, and Sarcopenic obesity—based on sarcopenia criteria, which included skeletal muscle mass index, grip strength, and physical function, as well as obesity criteria defined by body fat percentage. Baseline characteristics were analyzed, including evaluations of physical function, such as the Timed Up and Go (TUG) test, as well as PROs, such as the Health Assessment Questionnaire – Disability Index (HAQ-DI).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Sarcopenia was found in 19.6% of participants. Proportions of participants by group were as follows: Normal, 28.7%; Obesity, 51.7%; Sarcopenia, 11.2%; and Sarcopenic obesity, 8.4%. The median disease activity score suggested that remission was achieved in all groups. The TUG and HAQ-DI scores were highest in the Sarcopenic obesity group, showing a significant difference compared with all other groups. Other physical function assessments and PROs were also worse in the Sarcopenic obesity group compared with all other groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The proportion of sarcopenic obesity in the present study population of well-controlled RA patients was 8.4%. The Sarcopenic obesity group had significantly higher scores in TUG and HAQ-DI compared with all other groups. We observed not only reduced physical function but also a notable decline in quality of life, as evaluated by PROs, in patients with sarcopenic obesity. <b>Geriatr Gerontol Int 2025; 25: 1323–1331</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 10","pages":"1323-1331"},"PeriodicalIF":2.5,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144950337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
André Hajek, Larissa Zwar, Razak M Gyasi, Dong Keon Yon, Supa Pengpid, Karl Peltzer, Hans-Helmut König
{"title":"Loneliness and isolation: Are they associated with the wish for an earlier end of life?","authors":"André Hajek, Larissa Zwar, Razak M Gyasi, Dong Keon Yon, Supa Pengpid, Karl Peltzer, Hans-Helmut König","doi":"10.1111/ggi.70148","DOIUrl":"10.1111/ggi.70148","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To examine the association of loneliness and social isolation with the desired age at death among middle-aged and older adults in Germany.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Data were taken from the German Aging Survey (wave 8: nationally representative sample of community-dwelling individuals aged ≥43 years; <i>n</i> = 3826). The mean age equaled 69.3 years (SD 11.3 years, 43–99 years). Loneliness and social isolation were both quantified using psychometrically sound and widely used tools. Several sociodemographic, lifestyle-related and health-related covariates were included in linear regression analysis (with robust standard errors).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The mean desired age at death was 90.1 years (SD 8.0 years). Regressions showed that there was a robust association of loneliness (β = −1.47, <i>P</i> < 0.001) and social isolation (β = −1.49, <i>P</i> < 0.001) with lower desired age at death among the total sample, even after adjusting for a wide array of covariates. In the fully-adjusted model, such associations were also present among both men and women (with significant sex differences for the association between loneliness and the outcome; i.e., more pronounced association between loneliness and the desired age at death among men).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Loneliness (among men in particular) and social isolation were both associated with a lower desired age at death. This stresses the importance of tackling loneliness and social isolation in later life. It is of note that this is the very first study examining the association of loneliness and social isolation with the desired age at death. Thus, it can serve as a basis for future studies. <b>Geriatr Gerontol Int 2025; 25: 1412–1417</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 10","pages":"1412-1417"},"PeriodicalIF":2.5,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ggi.70148","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144855081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Standardizing shear wave elastography for sarcopenia assessment: A necessary step forward","authors":"Yi-Ching Chu, Chao-Chun Huang","doi":"10.1111/ggi.70147","DOIUrl":"10.1111/ggi.70147","url":null,"abstract":"<p>We read with great interest the recent systematic review by Gutiu <i>et al</i>. in <i>Geriatrics & Gerontology International</i>, titled “Muscle elasticity variations in assessing age-related changes in adults”.<span><sup>1</sup></span> The authors are to be commended for their excellent work in synthesizing the complex and often contradictory literature on the use of shear wave elastography (SWE) to assess age-related muscle changes.</p><p>The most cautionary conclusion of the review is the authors' inability to carry out a meta-analysis due to “substantial variability in methodologies” across studies.<span><sup>1</sup></span> This is not a limitation of the review, but a powerful statement on the current state of the field. This finding highlights a systemic issue: methodological inconsistency has become a primary barrier to translating SWE from a research tool to a clinical application, creating a critical “translational gap.” Without standardization, large-scale validation studies are impossible; without validation, SWE cannot be integrated into clinical guidelines, such as those defined by the European Working Group on Sarcopenia in Older People,<span><sup>2</sup></span> for the diagnosis and monitoring of sarcopenia. This is not an isolated problem; other reviews have similarly noted a “striking lack of consensus” and a “pressing need for developing standardized, validated scanning protocols” in musculoskeletal SWE research.<span><sup>3</sup></span></p><p>Therefore, we support and echo the conclusion of Gutiu <i>et al</i>. that “refining standardized SWE protocols” is an urgent priority.<span><sup>1</sup></span> We further propose the formation of an international working group composed of experts in geriatrics, radiology, rehabilitation medicine and biomedical engineering/physics. This cross-disciplinary collaboration is crucial, as the solution requires not only clinical consensus, but also the deep understanding of the underlying physics of SWE technology that physicists and engineers can provide, thereby bridging the gap between clinical needs and technical reality. The success of similar consensus-building initiatives in establishing standardized guidelines for liver elastography<span><sup>9</sup></span> and the broader push for structured reporting in radiology<span><sup>10</sup></span> underscore the feasibility and importance of such an endeavor.</p><p>Only through such rigorous standardization can we facilitate multicenter studies and meta-analyses, establish reliable normative reference values, and ultimately validate the full potential of SWE as a non-invasive, accessible biomarker in the diagnosis and management of sarcopenia and age-related muscle decline.</p><p>The authors received no specific funding for this work.</p><p>The authors declare no conflict of interest.</p><p>Y-CC conceived the study, carried out the literature search and drafted the manuscript. C-CH provided critical revision, supervised the project and is","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 10","pages":"1445-1446"},"PeriodicalIF":2.5,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ggi.70147","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144855082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Characteristics of Driving Risk Checklist-25 among community-dwelling older adults with mild cognitive impairment","authors":"Ayuto Kodama, Takuji Nakamura, Hideyuki Azuma, Yukiko Mouri, Yuji Tanaka, Hidenori Tochigi, Hidetaka Ota","doi":"10.1111/ggi.70127","DOIUrl":"10.1111/ggi.70127","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>With the rapid increase of aging societies worldwide, ensuring road safety among older adults has become a critical public health concern. This study aimed to assess driving risks among community-dwelling older adults with mild cognitive impairment (MCI).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A total of 387 participants aged 65 years and older were recruited from Akita Prefecture, Japan. Physical functions, such as walking speed and grip strength, cognitive functions, and depressive symptoms were evaluated alongside driving behaviors. Participants were classified into MCI-positive and MCI-negative groups based on cognitive assessments.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The results demonstrated significant differences in driving risk, physical performance, and cognitive abilities between the two groups. MCI-positive individuals exhibited higher driving risks and poorer functional performance. Receiver operating characteristic (ROC) curve analysis identified a cutoff score of 5.5 on the Driving Risk Checklist-25 (DRCL-25), with a sensitivity of 45.5% and specificity of 89.7% for identifying MCI.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>These findings underscore the importance of integrating physical and cognitive assessments to enhance the accuracy of driving risk evaluations. The DRCL-25 shows promise as a detection tool for MCI, facilitating the development of interventions aimed at maintaining mobility and improving road safety among older drivers. Future research should focus on refining the checklist and evaluating its applicability across diverse populations and settings. <b>Geriatr Gerontol Int 2025; 25: 1194–1199</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 9","pages":"1194-1199"},"PeriodicalIF":2.5,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12439236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144845530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fangyuan Cong, Lihua Deng, Rong Jia, Jie Liu, Jingtong Wang
{"title":"Ogilvie syndrome caused by varicella zoster virus: A case report","authors":"Fangyuan Cong, Lihua Deng, Rong Jia, Jie Liu, Jingtong Wang","doi":"10.1111/ggi.70142","DOIUrl":"10.1111/ggi.70142","url":null,"abstract":"<p>Ogilvie syndrome consists of dilatation of part or all of the colon and rectum without intrinsic obstruction or extrinsic inflammatory process. This disease has not yet been completely elucidated, but appears to be multifactorial.<span><sup>1</sup></span> Altered extrinsic regulation of colonic function by the sympathetic and parasympathetic nervous systems is the most commonly suggested mechanism for Ogilvie syndrome.<span><sup>2</sup></span> The relationship between varicella zoster virus (VZV) infection and the development of Ogilvie syndrome remains a rare, but clinically significant, phenomenon. VZV's impact on the autonomic nervous system is central to the development of Ogilvie syndrome, with neurogenic involvement being a primary mechanism.<span><sup>3</sup></span> Older adults are at high risk of this disease, and the symptoms might be atypical. This paper reports a 95-year-old male patient with Ogilvie syndrome after VZV infection.</p><p>The patient, a 95-year-old man, complained of “skin rash on the back for 12 days with abdominal pain for 5 days”. Twelve days earlier, the rash appeared on the right waist and abdomen, with a flaky red rash and protruding skin surface, accompanied by itching, pain and a burning sensation. He was diagnosed with herpes zoster, and was given ganciclovir orally and fusidic acid externally. Five days earlier, abdominal pain was manifested as jumping pain in the right upper abdomen, accompanied by abdominal distension in the middle and lower abdomen, and flatulence and defecation stopped. Three days earlier, the patient went to a nearby community hospital and was diagnosed with bowel obstruction. He was given fasting, rehydration and enema therapy, and abdominal symptoms were lightly relieved. Then, the patient was admitted to our department and denied a history of chronic diseases of the digestive system. He had a red rash and blisters on the right abdomen and back, some of which were shrinking and tender (see Fig. 1a), and abdominal physical examination suggested abdominal distension. There were no obvious abnormalities in laboratory tests. Abdominal and pelvic computed tomography showed that the sigmoid colon was long and locally went to the right upper abdomen with local wall thickening, and the upper lumen expanded with accumulated gas (see Fig. 1c). Colonoscopy showed poor intestinal preparation, but all intestinal segments were unobstructed, and no obvious abnormality was found in the mucosa (see Fig. 1d).</p><p>Combined with clinical symptoms and imaging examination, both computed tomography and colonoscopy excluded the causes of mechanical intestinal obstruction, so it was considered that the patient had a high probability of pseudo-obstruction. Considering the history of herpes zoster before abdominal symptoms, and T8–12 dermatomes involved, the final diagnosis was Ogilvie syndrome caused by VZV infection, and we confirmed our diagnosis again through literature retrieval.<span><sup>4</sup></span>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 9","pages":"1273-1275"},"PeriodicalIF":2.5,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12439230/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144845531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between health information-processing ability and frailty among community-dwelling older adults: A cross-sectional web-based study","authors":"Noriko Hori, Jiaqi Li, Yosuke Osuka","doi":"10.1111/ggi.70135","DOIUrl":"10.1111/ggi.70135","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Health literacy refers to the ability to understand and use health-related information, which underpins improvements in healthcare, disease prevention and health promotion. Although it is crucial for frailty prevention, the specific information-processing abilities associated with frailty remain unclear. This study aimed to clarify the association between information-processing ability and frailty in community-dwelling older adults.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This cross-sectional, web-based survey study was conducted on June 12–13, 2024, targeting 1032 independent adults aged ≥75 years. Frailty was assessed using the Questionnaire for Medical Checkup of Old-Old (score ≥4 indicating frailty). Health literacy was evaluated via the Health Literacy Survey European Questionnaire-47, dichotomized into “easy” or “difficult.” Multivariable logistic regression analysis was performed to examine associations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In total, 1032 participants (50.2% male) were analyzed, with frailty in 30.8%. Multivariable logistic regression, adjusted for age, sex, income, education and living situation, revealed significant associations between frailty and difficulties in “obtaining health information” across all domains. In the healthcare, disease prevention and health promotion domains, difficulty with “find where to get professional help when you are ill” (odds ratio [OR] = 1.42, 95% confidence interval [CI] = 1.01–1.99), “find information about vaccinations and health screenings that you should have” (OR = 1.89, 95% CI = 1.16–3.09) and “find information on healthy activities such as exercise, healthy food and nutrition” (OR = 1.77, 95% CI = 1.16–2.70), respectively, showed a high frailty risk.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>This study identified specific health information-processing abilities related to frailty. These findings provide valuable insights into the development of frailty prevention strategies. <b>Geriatr Gerontol Int 2025; 25: 1215–1222</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 9","pages":"1215-1222"},"PeriodicalIF":2.5,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144834841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lifestyle activities to protect against depressive symptoms after driving cessation among older adults: A longitudinal study","authors":"Fumio Sakimoto, Takehiko Doi, Hideaki Ishii, Soichiro Matsuda, Keitaro Makino, Hiroyuki Shimada","doi":"10.1111/ggi.70144","DOIUrl":"10.1111/ggi.70144","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To investigate whether lifestyle activities reduce the risk of depressive symptoms among older adults who have ceased driving.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This longitudinal, community-based study included 1654 community-dwelling older adults aged ≥60 years, excluding individuals with baseline depressive symptoms or without driver's licenses. Participants recruited from Takahama City, Aichi Prefecture, Japan, between September 2015 and February 2019 were categorized into driving and driving-cessation groups at baseline. Follow-up postal surveys were conducted over an average of 30.7 (standard deviation: 2.4) months. Depressive symptoms at 30 months were assessed using the Geriatric Depression Scale-15. Lifestyle activities were assessed using the 36-item Lifestyle Activities Questionnaire (LAQ), comprising 12 items each for physical, cognitive and social activities. Logistic regression analysis for each activity and the total LAQ score adjusted for potential covariates identified activities that had a protective role against depressive symptom development.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>During the follow-up period, 213 participants (13.6%) from the driving group (<i>n</i> = 1564) and 16 participants (17.8%) from the driving-cessation group (<i>n</i> = 90) developed depressive symptoms. Logistic regression analysis adjusted for covariates indicated that a higher total LAQ score was associated with depressive symptoms. Engagement in all activities reduced the risk of depressive symptoms in the driving group, whereas only engagement in cognitive activities reduced the risk in the driving-cessation group.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>High engagement in lifestyle activities was associated with a decreased risk of developing depressive symptoms. Hence, a conducive environment and support system are required to enhance engagement in lifestyle activities before older adults cease driving. <b>Geriatr Gerontol Int 2025; 25: 1316–1322</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 10","pages":"1316-1322"},"PeriodicalIF":2.5,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144803957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brijesh Sathian, Farah Rahat, Reham Kamal Aboshdid, Ebtehal Obeidat, Hanadi Al Hamad
{"title":"Challenging the independent role of sarcopenia in asthma mortality and lung function decline","authors":"Brijesh Sathian, Farah Rahat, Reham Kamal Aboshdid, Ebtehal Obeidat, Hanadi Al Hamad","doi":"10.1111/ggi.70145","DOIUrl":"10.1111/ggi.70145","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 10","pages":"1441-1442"},"PeriodicalIF":2.5,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144803955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gokcen Akyurek, Remziye Dilşah Şimşek, Özge Buket Arslan
{"title":"Quality of life in older individuals with chronic diseases: The role of depression and daily functioning","authors":"Gokcen Akyurek, Remziye Dilşah Şimşek, Özge Buket Arslan","doi":"10.1111/ggi.70141","DOIUrl":"10.1111/ggi.70141","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>This study aimed to identify the factors associated with quality of life (QoL) in older individuals with chronic diseases, focusing on the impact of depression and functional independence in daily activities within a primary care setting.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A cross-sectional study was carried out with 200 participants aged ≥65 years who had at least one diagnosed chronic diseases. Data were collected using a sociodemographic form, the Katz Index of Independence in Activities of Daily Living, the Lawton and Brody Instrumental Activities of Daily Living Scale, the Geriatric Depression Scale, and the Brief Older People's Quality of Life questionnaire. Multiple linear regression analysis was used to identify significant predictors of QoL.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The mean age of the participants was 72.92 ± 9.27 years. Depression (<i>β</i> = −0.669, <i>P</i> < 0.001), independence in activities of daily living (<i>β</i> = 0.171, <i>P</i> = 0.013) and the presence of additional chronic diseases (<i>β</i> = 0.137, <i>P</i> = 0.005) significantly predicted QoL, accounting for 64.6% of the variance (adjusted <i>R</i><sup>2</sup> = 0.611).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Depression and reduced independence in activities of daily living are key determinants of diminished QoL in older adults with chronic diseases. Routine screening for depressive symptoms, and interventions that promote functional autonomy are strongly recommended in primary care to support QoL in this population. <b>Geriatr Gerontol Int 2025; 25: 1301–1306</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 10","pages":"1301-1306"},"PeriodicalIF":2.5,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144803958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}