Geriatrics & Gerontology International最新文献

{"title":"Diabetes treatment: beyond glycemia","authors":"Hugo Gutierrez-Hermosillo, Enrique Díaz de León-González","doi":"10.1111/ggi.15030","DOIUrl":"10.1111/ggi.15030","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 1","pages":"132-133"},"PeriodicalIF":2.4,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142686722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between employment and cognitive function in older adults: A systematic review","authors":"Mai Takase,&nbsp;Keiko Sugiura,&nbsp;Isuzu Nakamoto,&nbsp;Saya Watanabe,&nbsp;Hiroshi Murayama","doi":"10.1111/ggi.15017","DOIUrl":"10.1111/ggi.15017","url":null,"abstract":"<p>The number of working older adults has been increasing in the past decade. Past studies have shown that working has a beneficiary effect on the health of older adults. One of the functions that older adults want to maintain is cognitive function, as this function is essential for an independent and high quality of life. Meanwhile, the association between employment &gt;60 years and cognitive function has not yet been organized. In this study, a systematic review was conducted to clarify the longitudinal association between working older adults and cognitive function. A computerized search was performed using PubMed, CINHAL, and PsycINFO for prospective studies published until July 2023. Of the 76 174 studies identified, six were included in the systematic review based on the inclusion and exclusion criteria. Four studies were from Asian countries (one from Taiwan and three from Japan), and two from the USA. Of the six studies, five reported an association between employment later in life and a lower risk of cognitive decline. Three studies examined the association by performing gender-specific analyses, reporting varied results. Overall, the results of this review suggest that the employment of older adults was positively associated with cognitive function over time. <b>Geriatr Gerontol Int 2024; 24: 1283–1291</b>.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"24 12","pages":"1283-1291"},"PeriodicalIF":2.4,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ggi.15017","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142667354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic accuracy analysis of SARC-F, its modified versions and the Quality of Life in Sarcopenia questionnaire in screening for sarcopenia in nursing home residents","authors":"Hilal ŞİMŞEK,&nbsp;Aslı UÇAR","doi":"10.1111/ggi.15020","DOIUrl":"10.1111/ggi.15020","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Sarcopenia, which is among the most important geriatric syndromes, is also a public health challenge. This study evaluated the performance of the SARC-F, its modified versions and the Quality of Life in Sarcopenia (SarQoL) in screening for sarcopenia.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>In the diagnostic accuracy study carried out with a total of 195 nursing home residents, sarcopenia was evaluated according to the European Working Group on Sarcopenia in Older Persons 2 algorithm. For SARC-CalFs, the calf circumference standard and its population-specific reference (31 cm, 32/33 cm, respectively) were used, whereas for SARC + elderly and body mass index information, age (&gt;75 years) and body mass index (&lt;21 kg/m²) were used. Screening test performance was evaluated with receiver operating characteristic analysis, and the optimal cut-off points were determined according to the Youden index.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The prevalence of sarcopenia was 33.8%. Although SarQoL and SARC-CalF scores were lower in individuals with sarcopenia, standard SARC-F and SARC-F + elderly and body mass index information scores were not different. SARC-F had the poorest screening performance, whereas the SarQoL scale had the best screening performance (area under the curve 0.502 vs 0.787). SARC-CalF (32/33 cm) had the best performance among the modified versions of SARC-F. The optimal cut-off point for SarQoL was &lt;64.56, and its sensitivity in sarcopenia screening was 74.24% (95% CI 62.0–84.2) and its specificity was 79.07% (95% CI 71.0–85.7). All the modified versions of SARC-CalF had higher sensitivity and area under the curve compared with SARC-F.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>SarQoL screening performance might be conducive to providing clinical discrimination in a nursing home sample. Further research is needed for the use of SarQoL as a potential sarcopenia screening strategy. Additionally, SARC-CalFs, especially the population-specific SARC-CalF (32/33 cm), might improve screening performance compared with standard SARC-F. <b>Geriatr Gerontol Int 2024; 24: 1335–1342</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"24 12","pages":"1335-1342"},"PeriodicalIF":2.4,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142667351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between cardiovascular disease risk and sarcopenia in community-dwelling Japanese older adults","authors":"Kazuhei Nishimoto,&nbsp;Kota Tsutsumimoto,&nbsp;Sho Nakakubo,&nbsp;Yuto Kiuchi,&nbsp;Yuka Misu,&nbsp;Tomoka Ohata,&nbsp;Hiroyuki Shimada","doi":"10.1111/ggi.15018","DOIUrl":"10.1111/ggi.15018","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Sarcopenia's high prevalence in older adults with cardiovascular disease (CVD) suggests that the risk of comorbidity in sarcopenia might also be increased during the at-risk phase of CVD. However, the relationship between CVD risk and sarcopenia has not been elucidated. Therefore, the purpose of this cross-sectional study was to investigate the association between CVD risk and sarcopenia in community-dwelling Japanese older adults.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The participants in this cross-sectional study included 14 923 community-dwelling Japanese older adults (mean age 73.2 ± 5.6 years). The present study estimated the CVD risk using the revised World Health Organization risk chart, and classified CVD risk into “low” (&lt;10%) and “mid-high” (≥10%). Assessments of sarcopenia, muscle mass, muscle strength and gait speed were measured based on the clinical definitions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Among the participants, 654 people (4.4%) had sarcopenia, and 4857 (32.6%) had CVD mid-high risk. A multiple logistic model showed that the CVD mid-high risk was associated with sarcopenia (odds ratio [OR] 1.55, 95% confidence interval [CI] 1.28–1.89). In addition, CVD mid-high risk was associated with low muscle mass (OR 1.74, 95% CI 1.50–2.01), low muscle strength (OR 1.25, 95% CI 1.14–1.37) and slow gait speed (OR 1.17, 95% CI 1.07–1.27) in the adjusted model.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Among community-dwelling older adults, high or moderate CVD risk was associated with an increased risk of sarcopenia. Our findings could help identify older adults with a future high risk for sarcopenia. <b>Geriatr Gerontol Int 2024; 24: 1328–1334</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"24 12","pages":"1328-1334"},"PeriodicalIF":2.4,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142618391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aphasia in Alzheimer's disease: Frequency and characteristics","authors":"Yuto Masuda,&nbsp;Masaki Kamiya,&nbsp;Ikue Ueda,&nbsp;Takako Yoshimura,&nbsp;Aiko Osawa,&nbsp;Shinichiro Maeshima","doi":"10.1111/ggi.15010","DOIUrl":"10.1111/ggi.15010","url":null,"abstract":"<p>Aphasia is frequently observed in Alzheimer's disease, with its prevalence increasing as the disease progresses. This study highlights the importance of recognizing early language impairments in Alzheimer's disease, and suggests that comprehensive language assessments are crucial for early diagnosis and effective communication interventions.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"24 12","pages":"1380-1381"},"PeriodicalIF":2.4,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142618381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to: Comments on Association of sleep traits with benign prostatic hyperplasia in middle-aged and elderly men: A prospective analysis in UK Biobank","authors":"Yougen Wu,&nbsp;Yuting Gu,&nbsp;Ju Xia,&nbsp;Guangchun Sun","doi":"10.1111/ggi.15019","DOIUrl":"10.1111/ggi.15019","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"24 12","pages":"1385-1386"},"PeriodicalIF":2.4,"publicationDate":"2024-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142618393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regional disparities in home health care utilization for older adults and their associated factors at the secondary medical area level: A Nationwide study in Japan","authors":"Yu Sun,&nbsp;Nobuo Sakata,&nbsp;Masao Iwagami,&nbsp;Satoru Yoshie,&nbsp;Ryota Inokuchi,&nbsp;Tomoko Ito,&nbsp;Naoaki Kuroda,&nbsp;Jun Hamano,&nbsp;Nanako Tamiya","doi":"10.1111/ggi.15011","DOIUrl":"10.1111/ggi.15011","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>As aging populations shift health care from hospitals to communities, Japan has implemented policies to promote home health care. This study explored regional differences in home health care recipients among older adults and related factors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We used nationwide data from 2020 to describe the proportion of older adults receiving regular home visits and the medical institutions utilized across secondary medical areas: urban, middle and depopulated areas. We examined factors associated with the proportion of patients receiving regular home visits. Exposures included each secondary medical area's medical and long-term-care (LTC) resources, adjusted for the older adult population; proportion of single-person households; and regional factors. We performed a multivariate negative binomial distribution analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 333 secondary medical areas were included. Urban areas had more patients receiving regular home visits, primarily from enhanced home care support clinics/hospitals (HCSCs). Fewer patients received regular home visits in depopulated areas, and conventional HCSCs were more common. Multivariate analysis revealed that the number of conventional HCSCs (coefficient, 0.17 [95% confidence intervals (CI), 0.08 to 0.26]), enhanced HCSCs (coefficient, 0.21 [95% CI, 0.14 to 0.29]) and population density (coefficient, 0.10 [95% CI, 0.02 to 0.19]) were positively associated with higher home-visit rates. Beds in LTC welfare facilities (coefficient, −0.10 [95% CI, −0.19 to −0.01]) and beds in LTC health facilities (coefficient, −0.09 [95% CI, −0.17 to 0.00]) were negatively associated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Policies to promote home health care have led to high home-visit rates in urban areas. Medical and LTC resources and regional factors influence disparities. As Japan's population ages, it is crucial to recognize these disparities and develop medical and LTC systems tailored to each region's characteristics. <b>Geriatr Gerontol Int 2024; 24: 1350–1361</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"24 12","pages":"1350-1361"},"PeriodicalIF":2.4,"publicationDate":"2024-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11628894/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142618392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Decadal changes in nocturia among American middle-aged and older men","authors":"Zhenjun Luo,&nbsp;Jie Wang,&nbsp;Shuai Huang,&nbsp;Xiaowei Hao,&nbsp;Kaikai Lv,&nbsp;Chao Lv,&nbsp;Guorong Yang,&nbsp;Qing Yuan","doi":"10.1111/ggi.15007","DOIUrl":"10.1111/ggi.15007","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To estimate the prevalence of nocturia in middle-aged and elderly men and evaluate its associated factors and changes over time.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Data of middle-aged and older men aged ≥40 years from the 2007–2008 and 2017–2020 cycles of the National Health and Nutrition Examination Survey were retrospectively analyzed. The prevalence of nocturia was estimated using participant questionnaires on nocturia, lifestyle-related factors, and health factors, and its decadal changes were examined using multivariate logistic regression analysis to determine related factors associated with the prevalence of nocturia.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The prevalence of nocturia was 38.0% in 2007–2008 and 39.6% in 2017–2020, with no significant increase observed (<i>P</i> = 0.3989). Being a non-Hispanic black was positively correlated with nocturia (adjusted odds ratio [AOR] = 1.54, 1.22–1.93, <i>P</i> &lt; 0.001), whereas the correlation with being a Mexican American disappeared (AOR = 1.25, 0.90–1.73, <i>P</i> = 0.187). Diabetes (AOR = 1.32, 1.07–1.64, <i>P</i> = 0.010) and sleep disorders (AOR = 1.31, 1.07–1.60, <i>P</i> = 0.008) showed a statistically significant positive correlation with nocturia, whereas a significant negative correlation was observed between employment (AOR = 0.66, 0.54–0.82, <i>P</i> &lt; 0.001) and nocturia. Above-high-school education (AOR = 0.60, 0.47–0.76, <i>P</i> &lt; 0.001) showed a constant trend toward a negative correlation with nocturia. The correlation between high school education or general educational development and nocturia disappeared (AOR = 0.81, 0.62–1.05, <i>P</i> = 0.112).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Diabetes and sleep disorders contribute to the development of nocturia, while work and high educational attainment can actively combat nocturia. <b>Geriatr Gerontol Int 2024; 24: 1308–1314</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"24 12","pages":"1308-1314"},"PeriodicalIF":2.4,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations among frailty conditions and pain indicators: Data from 22 356 European older adults","authors":"Trinidad Sentandreu-Mañó,&nbsp;Elena Marques-Sule,&nbsp;Pallav Deka,&nbsp;José M Tomás,&nbsp;Leiver Andrés Romero Pintado,&nbsp;Leonie Klompstra,&nbsp;Hady Atef","doi":"10.1111/ggi.15016","DOIUrl":"10.1111/ggi.15016","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Recent studies supported the presence of a relationship between pain and frailty, but more research is needed to highlight the pain–frailty association. The study aimed to investigate the prevalence and the influence of different pain indicators on frailty while controlling for age, sex and country.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This observational study used data from the sixth wave of the SHARE survey. A sample of 22 356 community-dwelling individuals aged &gt;60 years from six European countries (Spain, Estonia, France, Greece, Czech Republic and Sweden) was analyzed. The pain was measured through assessment of medication used for joint pain or other types of pain, pain location, polypharmacy and pain level. Frailty was assessed with the modified Fried Frailty phenotype.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Pain indicators, especially widespread pain and pain severity, were significantly associated with prefrailty (odds ratio 3.30, 95% CI 2.40, 4.55; and odds ratio 0.61, 95% CI 0.51, 0.72) and frailty status (odds ratio 4.69, 95% CI 3.31, 6.67; and odds ratio 0.37, 95% CI 0.30, 0.44). Advancing age and female sex consistently correlated with increased prefrailty (odds ratio 1.06, 95% CI 1.05, 1.07; and odds ratio 1.36, 95% CI 1.22, 1.53) and frailty risk (odds ratio 1.11, 95% CI 1.10, 1.12; and odds ratio 1.71, 95% CI 1.48, 1.96). Country-specific differences emerged, with Spaniards showing higher odds ratios of prefrailty and frailty compared with Swedish, French and Czech individuals, whereas Greeks showed elevated odds ratios compared with Spaniards. The factors associated jointly explained 27.5% of the variance in frailty categories.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Significant associations were identified, particularly with widespread pain and pain severity, highlighting their impact on frailty. Country-specific variations in frailty prevalence were observed, alongside consistent associations with advancing age and female sex. These findings provide valuable insights into the intricate interplay between pain and frailty, offering the potential for targeted interventions in older adults' care through tailored pain management strategies. <b>Geriatr Gerontol Int 2024; 24: 1362–1369</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"24 12","pages":"1362-1369"},"PeriodicalIF":2.4,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11628897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between self-reported weight loss and new long-term care insurance certifications: A 9-year Japanese older adult cohort study","authors":"Ryo Katayose,&nbsp;Mika Okura,&nbsp;Ayae Kinoshita,&nbsp;Sora Shimamura,&nbsp;Saki Tanaka,&nbsp;Hidenori Arai,&nbsp;Mihoko Ogita","doi":"10.1111/ggi.15015","DOIUrl":"10.1111/ggi.15015","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>This cohort study aimed to assess weight loss associated with new long-term care insurance (LTCI) certifications over a 9-year period, accounting for the competing risk of death.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We analyzed data from 3749 Japanese individuals aged ≥65 years in Kami Town, Hyogo Prefecture, Japan. Weight loss was assessed using the Kihon Checklist during the baseline survey. Data regarding LTCI certifications were collected until March 2022. Cox proportional hazards models were used to calculate adjusted hazard ratios (HRs) of 9-year LTCI certification because of weight loss, adjusted for confounding factors. To exclude the effect of competing risks, Fine-Gray regression was used to estimate subdistribution HRs. Subgroup analyses were carried out after the examination of potential interactions between subjective cognitive function, body mass index categories and weight loss.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The incidence rate of new LTCI certifications was 5.16 per 100 person-years overall – broken down into 7.02 for those with weight loss and 4.97 for those without. The adjusted HR for weight loss to new LTCI certifications was 1.35 (95% CI 1.15–1.59). Considering mortality as a competing risk, the adjusted subdistribution HR was 1.37 (95% CI 1.16–1.61). Conversely, no interaction was observed between weight loss and subjective cognitive function or body mass index categories.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Excluding the effect of mortality, weight loss was identified as a risk factor for new LTCI certifications. However, no interaction was observed between weight loss and subjective cognitive function or body mass index categories. <b>Geriatr Gerontol Int 2024; 24: 1320–1327</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"24 12","pages":"1320-1327"},"PeriodicalIF":2.4,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142582629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}