Fabien Coisy, Chloé Desbrosses, Thibaut Markarian, Laura Grau-Mercier, Sarah Lavielle, Dino Tikvesa, Xavier Bobbia, Romain Genre Grandpierre
{"title":"Thirty-day survival rate of patients having a treatment withholding or treatment withdrawal decision in the emergency department: A retrospective monocentric study","authors":"Fabien Coisy, Chloé Desbrosses, Thibaut Markarian, Laura Grau-Mercier, Sarah Lavielle, Dino Tikvesa, Xavier Bobbia, Romain Genre Grandpierre","doi":"10.1111/ggi.70013","DOIUrl":"10.1111/ggi.70013","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Treatment withholding or withdrawal (TWW) is frequent in the emergency department (ED). Most studies on this topic only study patients who die in the ED. The main aim of this study was to determine 30-day mortality after a TWW decision in the ED, for patients discharged alive from ED.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This was a retrospective monocentric study conducted from January 1, 2020, to March 31, 2022, in a university hospital in France. Classes of TWW levels were low, medium and high, corresponding to do-not-resuscitate order, treatment withholding and treatment withdrawal, respectively. The secondary aim was to determine if there were predictive factors of survival among patients with medium-level TWW.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Overall, 280 patients were included and 219 (78%) were analyzed, with mean age of 82 (±12) years. Respectively, 12 (5%), 145 (66%) and 62 (28%) had a low, medium, or high level of TWW. A total of 78 (36% [95% CI, 29%–42%]) patients were alive on day 30 following their ED admission: 7 (11%) with a high level, 63 (43%) with a medium level and 8 (67%) with a low level. No difference was found after adjustment between surviving and nonsurviving patients having a medium TWW level.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Among patients having a TWW decision in the ED, 36% of patients were alive at 30 days. The decision to limit some therapeutics for patients does not mean an imminent death, and those patients need adequate care. The care pathway for these patients must be organized accordingly. <b>Geriatr Gerontol Int 2025; 25: 528–534</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 4","pages":"528-534"},"PeriodicalIF":2.4,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143523141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Relationships between elementary school children's experiences in helping older adults and their attitudes toward individuals with dementia and intention to help: A cross-sectional survey aiming to develop age-friendly education","authors":"Ayumi Igarashi, Manami Takaoka, Hiroshige Matsumoto, Noriko Yamamoto-Mitani","doi":"10.1111/ggi.70014","DOIUrl":"10.1111/ggi.70014","url":null,"abstract":"<p>A survey of 116 sixth-grade students found that 39% had supported older adults in the past year. Those with prior experience showed significantly higher attitudes and helping intentions toward people with dementia. Encouraging practical helping experiences may foster awareness and willingness to assist older adults in the community.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 4","pages":"633-634"},"PeriodicalIF":2.4,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ggi.70014","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143515354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Toshitaka Sawamura, Shigehiro Karashima, Ai Ohmori, Mitsuhiro Kometani, Takashi Yoneda
{"title":"Impacts of tirzepatide on older patients with diminished β-cell function and dementia","authors":"Toshitaka Sawamura, Shigehiro Karashima, Ai Ohmori, Mitsuhiro Kometani, Takashi Yoneda","doi":"10.1111/ggi.70018","DOIUrl":"10.1111/ggi.70018","url":null,"abstract":"<p>Tirzepatide could control postprandial hyperglycemia even in cases with diminished β-cell function. This finding gives new insight into the treatment of older patients with diabetes. However, tilzepatide does not replace basal insulin in cases with diminished β-cell function and requires careful observation for sarcopenia.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 4","pages":"630-632"},"PeriodicalIF":2.4,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ggi.70018","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143500212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reply to comment on “Regional disparities in home health care utilization for older adults and their associated factors at the secondary medical area level: A nationwide study in Japan”","authors":"Yu Sun, Nobuo Sakata, Masao Iwagami, Satoru Yoshie, Ryota Inokuchi, Tomoko Ito, Naoaki Kuroda, Jun Hamano, Nanako Tamiya","doi":"10.1111/ggi.70015","DOIUrl":"10.1111/ggi.70015","url":null,"abstract":"<p>We sincerely appreciate Luthfiyah <i>et al</i>.'s interest in and comments<span><sup>1</sup></span> on our recently published work in <i>Geriatrics and Gerontology International</i>.<span><sup>2</sup></span> They expressed concerns regarding (1) data aggregation at the secondary medical area level, (2) the exclusion of patient-specific variables, and (3) the lack of dynamics between facility-based and home-visit care. We have provided responses to address these points and to clarify and contextualize our findings.</p><p>First, as mentioned in the limitations of our study, we used “secondary medical areas” as the unit of analysis because they were the smallest geographic units available in the National Database (NDB) Open Data. As Luthfiyah <i>et al</i>. suggested, future studies could benefit from analyzing smaller units, such as municipalities, to enhance the precision of findings and guide more localized interventions. However, it is important to note that “secondary medical areas” in Japan are integral to planning the medical provision system.<span><sup>3</sup></span> Moreover, using municipalities as the unit of analysis would reveal that approximately half of them lack enhanced home care support clinics,<span><sup>4</sup></span> which could lead to instability in multivariate analysis models. Therefore, we believe that it is appropriate to capture overall trends in regional disparities at the secondary medical area level.</p><p>Second, because our study used aggregated data, we could not access individual-level patient data or adjust for patient-specific factors. This limitation suggests that patients who receive home visits may have different characteristics depending on their region. Moreover, there is the possibility that home visits may be disproportionately provided to patients with lower actual needs (such as to patients capable of visiting medical institutions) in regions with high home-visit utilization rates. To address this issue, our ongoing study has leveraged individual-level data from the NDB, enabling adjustments for patient-specific variables and providing deeper insights into regional differences in home healthcare utilization.</p><p>Third, as Luthfiyah <i>et al</i>. pointed out, home-visit care and long-term care (LTC) facilities often exhibit a complementary relationship. In line with this, our study found a negative association between home-visit rates and the number of beds in the LTC welfare and health facilities within a region. As described in the Discussion section, this suggests that in depopulated areas with fewer home-visit care services available, a higher proportion of older adults tend to reside in LTC facilities. In Japan, visiting medical care is also provided in non-LTC facilities, such as assisted-living facilities with services and group homes for patients with dementia. In an additional analysis, we included the visiting medical care provided to these non-LTC facilities to examine regional disparities ","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 4","pages":"646-647"},"PeriodicalIF":2.4,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ggi.70015","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143500217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Expanding perspectives on workload and emotional exhaustion among older assistant care workers: A commentary on Ma et al.","authors":"Lien-Chung Wei, Hsien-Jane Chiu","doi":"10.1111/ggi.70001","DOIUrl":"10.1111/ggi.70001","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 4","pages":"637-638"},"PeriodicalIF":2.4,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143491708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jaya Singh Kshatri, Daisy J.A. Janssen, Susan D. Shenkin, Asit Mansingh, Sandipana Pati, Subrata Kumar Palo, Sanghamitra Pati
{"title":"Comprehensive geriatric assessment in nonhospitalized settings: An overview of systematic reviews","authors":"Jaya Singh Kshatri, Daisy J.A. Janssen, Susan D. Shenkin, Asit Mansingh, Sandipana Pati, Subrata Kumar Palo, Sanghamitra Pati","doi":"10.1111/ggi.70004","DOIUrl":"10.1111/ggi.70004","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Comprehensive geriatric assessment (CGA) is a commonly used intervention for addressing the health needs of older people. Traditionally used for hospital inpatients, there is inconclusive evidence on its effectiveness in other settings. This overview of reviews aims to synthesize the current evidence regarding CGA models, their effectiveness, feasibility and acceptability in nonhospital settings.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methodology</h3>\u0000 \u0000 <p>The overview included systematic reviews with or without meta-analysis reporting on older adults (≥50 years) undergoing CGA in primary care facilities, outpatient care, community-based programs, long-term care settings and home-based care, excluding narrow high-risk groups or specific disease conditions. MEDLINE, Embase, Cochrane CENTRAL, PsychInfo and CINAHL, were searched up to August 2023, with blinded double screening and data extraction. Review quality was assessed using Assessing the Methodological Quality of Systematic Reviews-2.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of 2574 identified articles, 22 systematic reviews (478 primary studies, >136 336 participants) met the inclusion criteria. Most reviews were of moderate to good quality, 73% were based in community or home settings, and in 50% of the reviews the participants were aged ≥65 years. They identified diverse CGA models without uniform definition or domains of assessment, most delivered by nurses and multidisciplinary teams, with variation of input duration (6–36 months) and poor reporting of frequency of assessment or follow-up duration. Most reviews found no effect of CGA on rates of admission to hospitals or long-term care facilities, quality of life or function. Of the 10 reviews that reported it as an outcome, only two found that CGA reduced mortality risk by 13% and 14% at longest follow-up. Of the three reviews reporting frailty as an outcome, two showed benefit, with one meta-analysis showing significant reduction in frailty (relative risk, 0.77 [95% CI, 0.64–0.93]). The acceptability of CGA is good among care providers, but limited information was found among patients. Facilitators for implementation identified include preexisting interprofessional working, skilled staff, better informed patients and focus on patient convenience. The evidence was exclusively from high-income countries.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>CGA models are highly heterogenous across domains, delivery, dosage and frequency. Most systematic reviews show little to no evidence of benefit of CGA on rates of hospitali","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 4","pages":"491-503"},"PeriodicalIF":2.4,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ggi.70004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Merve Yilmaz Kars, Ilyas Akkar, Orhan Cicek, Zeynep Iclal Turgut, Mustafa Hakan Dogan, Muhammet Cemal Kizilarslanoglu
{"title":"Comment on: Association between self-reported weight loss and new long-term care insurance certifications: A 9-year Japanese older adult cohort study","authors":"Merve Yilmaz Kars, Ilyas Akkar, Orhan Cicek, Zeynep Iclal Turgut, Mustafa Hakan Dogan, Muhammet Cemal Kizilarslanoglu","doi":"10.1111/ggi.70011","DOIUrl":"10.1111/ggi.70011","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 4","pages":"644-645"},"PeriodicalIF":2.4,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmed Mohammed Hassan Haroun, Mona Hegazy Mohamed, Marwa Abd El Azeem Abd EL Gawad, Doha Rasheedy
{"title":"Development and validation of a new tool for simultaneous screening of malnutrition, sarcopenia and cachexia in older adults","authors":"Ahmed Mohammed Hassan Haroun, Mona Hegazy Mohamed, Marwa Abd El Azeem Abd EL Gawad, Doha Rasheedy","doi":"10.1111/ggi.70010","DOIUrl":"10.1111/ggi.70010","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>The high prevalence of malnutrition, sarcopenia and cachexia among older adults presents a significant health care challenge, underscoring the need for effective screening tools. Given the frequent overlap of these conditions, a tool capable of simultaneously screening for all three conditions is imperative.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The development process included an extensive review of existing assessment instruments and data on risk factors, clinical presentations, and consequences of the three conditions. The tool underwent rigorous testing to evaluate its reliability and validity in a sample of 300 older adults. It was compared against standard diagnostic criteria and assessed alongside other screening tools, including the Mini Nutritional Assessment-Short Form, the Short Nutritional Assessment Questionnaire and the Simple Questionnaire to Rapidly Diagnose Sarcopenia.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Eighteen percent (<i>n</i> = 54) of participants were diagnosed with an overlap of the three conditions, 10% (<i>n</i> = 30) of cases presented with sarcopenia alone and 3% (<i>n</i> = 10) were diagnosed with malnutrition only. The new tool demonstrated Cronbach's alpha of 0.818 and high construct validity. The newly developed tool and Mini Nutritional Assessment–Short Form had the highest diagnostic accuracy for predicting the malnutrition and sarcopenia. The Short Nutritional Assessment Questionnaire had the highest diagnostic accuracy for predicting cachexia, whereas the Simple Questionnaire to Rapidly Diagnose Sarcopenia exhibited the lowest diagnostic accuracy across all conditions. The retention criteria for items were deemed valid for the 19 items included in the finalized version of the new tool.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Screening for malnutrition, sarcopenia and cachexia in older adults using a single tool was feasible. The new tool was easy to use and did not require anthropometric measurements or physical performance tasks. <b>Geriatr Gerontol Int 2025; 25: 511–519</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 4","pages":"511-519"},"PeriodicalIF":2.4,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143457549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response to the Letter to the Editor, “Is oral frailty a cause or a consequence?”","authors":"Masanori Iwasaki, Maki Shirobe, Keiko Motokawa, Tomoki Tanaka, Kazunori Ikebe, Takayuki Ueda, Shunsuke Minakuchi, Masahiro Akishita, Hidenori Arai, Katsuya Iijima, Hiroyuki Sasai, Shuichi Obuchi, Hirohiko Hirano","doi":"10.1111/ggi.70006","DOIUrl":"10.1111/ggi.70006","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 4","pages":"640-641"},"PeriodicalIF":2.4,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143457568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reconstruction of a resilient and secure community and medical care system in the coronavirus era – English translation of the Japanese opinion released from the Science Council of Japan","authors":"Katsuya Iijima, Masahiro Akishita, Tamao Endo, Tetsuo Ichikawa, Norio Ozaki, Kouetsu Ogasawara, Yasuki Kihara, Masafumi Kuzuya, Hiroko Komatsu, Hiroko Terasaki, Yuichiro Doki, Haruko Noguchi, Kiyoko Nishi, Yumi Nishimura, Nobuhiko Haga, Motohiko Miyachi, Dr Seiji Yasumura PhD, Junko Wake, Hidenori Arai","doi":"10.1111/ggi.15073","DOIUrl":"10.1111/ggi.15073","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Over 3 years have passed since the outbreak of novel coronavirus disease 2019 (COVID-19), a disease associated with a high risk of severe illness and death among older individuals. This period has brought to light regional and social issues, including issues in overall and regional healthcare, that existed before the epidemic. “COVID-19-related frailty” is defined as secondary damage to health caused by inactivity and disconnection from human interaction owing to prolonged isolation among older individuals. Now in its fourth year, COVID-19 cannot be taken lightly, even though it is now a Category 5 infectious disease. Looking at it from the perspective of the Corona (COVID-19)/post-Corona (COVID-19) era and society, it is necessary to reconstruct regional communities in which active residents can resume their activities, a resilient regional society from multiple perspectives, and a medical and care system that can give the public a sense of security, all of which will lead to the development of local communities.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Current situation and problems</h3>\u0000 \u0000 <div>\u0000 <ol>\u0000 \u0000 <li>Weak healthcare systems in emergencies such as emerging infectious diseases and disasters</li>\u0000 </ol>\u0000 </div>\u0000 \u0000 <div>The COVID-19 pandemic has posed challenges in the management of older individuals in Japan. These challenges are common to those encountered with other emerging infectious diseases and disasters; however, the pandemic has emphasized the vulnerability of older adults.\u0000 <ol>\u0000 \u0000 <li>End-of-life care and advance care planning do not function during a contingency</li>\u0000 </ol>\u0000 </div>\u0000 \u0000 <div>The COVID-19 pandemic has had a significant effect on the end-of-life (EOL) care of older adults, with the lack of implementation and dysfunction of advance care planning (ACP) identified as the biggest factors. This has made it difficult for this population to share their values, intentions, and life goals with their families and healthcare providers.\u0000 <ol>\u0000 \u0000 <li>Inadequate use of information and communication technology and the latest technologies</li>\u0000 </ol>\u0000 </div>\u0000 \u0000 <div>Disparity in the digital field (digital divide) is more pronounced among older individuals. Consequently, the benefits of new technologies, such as digitalization and robotics, have not fully reached older individuals, leading to social isolation and frailty in this population.\u0000 <ol>\u0000 ","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 4","pages":"481-490"},"PeriodicalIF":2.4,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ggi.15073","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143457553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}