Geriatrics & Gerontology International最新文献

{"title":"Localized AL amyloidosis of the breast in a geriatric female","authors":"Nicholas Renton,&nbsp;Riddhi Amin,&nbsp;Nina L. Blachman","doi":"10.1111/ggi.14952","DOIUrl":"10.1111/ggi.14952","url":null,"abstract":"<p>Localized breast amyloidosis is often found incidentally on mammography or ultrasound, as amyloid deposits can be calcified and mimic malignancy. Although rare, breast amyloidosis should be considered a possible etiology of abnormal mammography findings in older women.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"24 9","pages":"982-983"},"PeriodicalIF":2.4,"publicationDate":"2024-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141901419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validating respiratory sarcopenia diagnostic criteria by mortality based on a position paper by four professional organizations: Insights from the Otassha study","authors":"Takeshi Kera,&nbsp;Hisashi Kawai,&nbsp;Manami Ejiri,&nbsp;Keigo Imamura,&nbsp;Hirohiko Hirano,&nbsp;Yoshinori Fujiwara,&nbsp;Kazushige Ihara,&nbsp;Shuichi Obuchi","doi":"10.1111/ggi.14937","DOIUrl":"10.1111/ggi.14937","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>The Japanese Society for Respiratory Care and Rehabilitation, Japanese Association on Sarcopenia and Frailty, Japanese Society of Respiratory Physical Therapy, and Japanese Association of Rehabilitation Nutrition proposed the definition and diagnosis of respiratory sarcopenia using low respiratory muscle strength and appendicular skeletal muscle mass (ASM; ASM/height²) instead of respiratory muscle mass; however, these parameters have not been validated. This study aimed to confirm the validity of the respiratory sarcopenia definition proposed by these four professional organizations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Participants of our cohort study in 2015 of 468 community-dwelling older people who were evaluated for sarcopenia and underwent spirometry were included in this analysis. We determined two respiratory sarcopenia models based on low skeletal muscle mass and respiratory muscle strength. Low skeletal muscle mass was defined by low ASM/height², and low respiratory muscle strength was defined by peak expiratory flow rate (PEFR) or percentage of predicted PEFR (%PEFR). Survival status was assessed 5 years after baseline assessment (in 2020). To evaluate the validity of the cut-off values for PEFR and %PEFR, we determined different respiratory sarcopenia models by sequentially varying the cut-off values for each parameter, including ASM/height², from high to low. We subsequently calculated the hazard ratio (HR) for mortality for each respiratory sarcopenia model using the Cox proportional hazards model. Additionally, we plotted the HR for each combination of cut-off values for ASM/height² and PEFR or %PEFR on a three-dimensional chart to observe the relationship between the different cut-off values and HR.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 31 people died during the 5-year observation period. With ASM/height² cut-off values of approximately 7.0 kg/m² for men and 5.7 kg/m² for women and %PEFR cut-off values of 66–75%, respiratory sarcopenia was associated with mortality risk (HR, 2.36–3.27, point estimation range).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The definition of respiratory sarcopenia by the four professional organizations is related to future health outcomes, and this definition is valid. <b>Geriatr Gerontol Int 2024; 24: 948–953</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"24 9","pages":"948-953"},"PeriodicalIF":2.4,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141897249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unexpected improvement of resistant hypertension in older adults: A red flag sign","authors":"Ami Schattner MD","doi":"10.1111/ggi.14954","DOIUrl":"10.1111/ggi.14954","url":null,"abstract":"&lt;p&gt;Resistant hypertension is defined as failure to reach blood pressure (BP) targets despite the use of three classes of antihypertensive drugs, including a diuretic, at their maximal tolerated doses.&lt;span&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/span&gt; A recent meta-analysis including 91 studies and &gt;3 million patients with essential hypertension reported a prevalence of 10.3% for resistant hypertension, higher with advancing age or chronic kidney disease.&lt;span&gt;&lt;sup&gt;2&lt;/sup&gt;&lt;/span&gt; The National Health and Nutrition Examination Surveys database also identified older age as a distinct risk factor for refractory hypertension.&lt;span&gt;&lt;sup&gt;3&lt;/sup&gt;&lt;/span&gt; These patients pose a therapeutic challenge, because of their increased risk of major adverse cardiovascular events and end-organ damage.&lt;span&gt;&lt;sup&gt;4&lt;/sup&gt;&lt;/span&gt; Thus, invasive treatments, such as renal denervation, had been tried, including among older adult patients, but remain under clinical trial.&lt;span&gt;&lt;sup&gt;5, 6&lt;/sup&gt;&lt;/span&gt; In contrast, patients with longstanding resistant hypertension that suddenly spontaneously resolved are rarely encountered. Two such patients are briefly reported to suggest different mechanisms of this unusual, poorly-reported occurrence and its potentially urgent clinical significance in older adults.&lt;/p&gt;&lt;p&gt;A 92-year-old community-dwelling woman had a long history of primary isolated systolic hypertension and chronic obstructive pulmonary disease on budesonide inhaler treatment. The chronic obstructive pulmonary disease (Global Initiative for Chronic Obstructive Lung Disease 3 when last tested a few months prior) did not cause dyspnea on effort, as she was bedridden for most of the day, helped by a caretaker. She had never been hospitalized, and adhered to a low-salt diet and medications administered by her live-in caregiver, including candesartan 16 mg/day, amlodipine 10 mg/day, bisoprolol 5 mg/day and clonidine 0.3 mg b.i.d. (thiazides could not be tolerated due to hyponatremia). Nevertheless, frequent episodic asymptomatic BP recordings of &gt;200/83 mmHg continued, confirmed by 24-h Holter monitoring. I was consulted after her son became concerned that her BP readings suddenly were “too good”: 130/80 mmHg, without peaks. She was found apathetic, and was referred immediately to the hospital where respiratory acidosis and hypercapnic respiratory failure was detected (pH 7.269, PCO&lt;sub&gt;2&lt;/sub&gt; 95). There were no other contributing associated conditions, such as chest infection. She was intubated, admitted to the intensive care unit and later discharged home on non-invasive ventilation, resuming her full anti-hypertensive treatment shortly after.&lt;/p&gt;&lt;p&gt;A 76-year-old banker with a long history of primary hypertension and prediabetes (HbA1c 6.3%) was receiving valsartan 320 mg/day, disothiazide 25 mg/day, eplerenone 25 mg/day, bisoprolol 10 mg/day and metformin. Nevertheless, 24-h ambulatory blood pressure monitoring showed frequently abnormal BP (systolic 100%, diastolic 77% of the time). At home, val","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"24 9","pages":"983-985"},"PeriodicalIF":2.4,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ggi.14954","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141893239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementation status of comprehensive geriatric assessment among older inpatients: A nationwide retrospective study","authors":"Tatsuya Hosoi,&nbsp;Hayato Yamana,&nbsp;Shoya Matsumoto,&nbsp;Hiroki Matsui,&nbsp;Kiyohide Fushimi,&nbsp;Masahiro Akishita,&nbsp;Hideo Yasunaga,&nbsp;Sumito Ogawa","doi":"10.1111/ggi.14953","DOIUrl":"10.1111/ggi.14953","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>The importance of comprehensive geriatric assessment (CGA) is increasing in aging societies worldwide. However, there are few comprehensive studies on CGA, resulting in a limited understanding of its implementation rate, temporal changes and factors associated with its implementation. We aimed to investigate the implementation status of CGA and its regional variance in Japan.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Using the Diagnosis Procedure Combination database, we investigated CGA trends, and identified the patient, hospital and regional factors associated with its implementation. We identified patients aged ≥65 years who were admitted for the first time between 2016 and 2020 with a diagnosis of stroke, heart failure, pneumonia, bone fracture or colorectal cancer. We examined the CGA implementation rate according to patient and hospital characteristics. We also investigated temporal changes and tendencies to carry out CGA in different prefectures.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 1 974 817 patients were analyzed, of whom 570 696 (28.9%) underwent CGA. The implementation trend increased steadily from 25.3% in fiscal year 2016 to 33.4% in fiscal year 2019. The implementation rate also increased with patient age (30.3% in patients aged ≥95 years). Regional variations in its implementation status were observed, with a higher tendency to be implemented in areas near major metropolitan regions. A trend toward carrying out CGA for colorectal cancer, but not for other diseases, has been observed in eastern Japan.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Although CGA is increasingly carried out, considerable regional differences remain in its implementation status. Initiatives to reduce variations are necessary. <b>Geriatr Gerontol Int 2024; 24: 904–911</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"24 9","pages":"904-911"},"PeriodicalIF":2.4,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ggi.14953","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141893238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Economic burden of frailty in older adults accessing community-based aged care services in Australia","authors":"Barbara Toson,&nbsp;Laura Catherine Edney,&nbsp;Hossein Haji Ali Afzali,&nbsp;Renuka Visvanathan,&nbsp;Jyoti Khadka,&nbsp;Jonathan Karnon","doi":"10.1111/ggi.14955","DOIUrl":"10.1111/ggi.14955","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To explore the utilization of permanent residential aged care (PRAC), healthcare costs, and mortality for frail compared with non-frail individuals following their first assessment by an aged care assessment team (ACAT) for a government-funded home care package.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The study involved people aged 65 years and over who completed their first ACAT assessment in 2013 and were followed for up to 36 months. Frail and non-frail study participants were matched through caliper matching without replacement to adjust for potential unobserved confounders. Poisson regression estimated the impact of frailty on PRAC admission and mortality rates. Healthcare costs, encompassing hospital admissions, emergency department presentations, primary care consultations, and pharmaceutical use, from ACAT assessment to end of follow-up, PRAC entry or death were summarized monthly by frailty status.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>13 315 non-frail controls were matched with up to three frail individuals (52 678 total). Frail individuals experienced higher mortality (incidence rate ratio [IRR] = 1.76; 95% confidence interval [CI] 1.70–1.83) and greater likelihood of entering PRAC (IRR = 1.73; 95% CI 1.67–1.79) compared with non-frail individuals. Total healthcare costs over the 3-year post-assessment period for 39 363 frail individuals were $1 277 659 900, compared with expected costs of $885 322 522 had they not been frail. The primary contributor to the mean monthly excess cost per frail individual (mean = $457, SD = 3192) was hospital admissions ($345; 75%).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Frailty is associated with higher rates of mortality and of entering PRAC, and excess costs of frailty are substantial and sustained over time. These findings emphasize the potential economic value of providing home care for older people before they become frail. <b>Geriatr Gerontol Int 2024; 24: 939–947</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"24 9","pages":"939-947"},"PeriodicalIF":2.4,"publicationDate":"2024-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ggi.14955","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141888973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Senotherapy preserves resilience in aging","authors":"Takumi Mikawa,&nbsp;Kazumichi Yoshida,&nbsp;Hiroshi Kondoh","doi":"10.1111/ggi.14949","DOIUrl":"10.1111/ggi.14949","url":null,"abstract":"<p>In aging societies, social and economic burdens of aging-related diseases are increasing significantly. Senotherapy, which targets aging by eliminating senescent cells (senolytics) or removing sources of chronic inflammation (senostatics), are proposed as novel strategies for aging-related diseases. Aged or frail people suffer a decline of tissue reserve capacity during aging. Resilience, which is much reduced in older people, is essential for recovery from diseases, stresses or crises. Impaired resilience is one of the reasons why aged people experience a gradual waning of their daily activity and an increase of multimorbidity. Calorie restriction results in senostatic alleviation of chronic inflammation, whereas senolytic drugs induce apoptosis of senescent cells, which exacerbate aging by excreting inflammatory factors. Thus, both senolytics and senostatics are expected to reduce sterile inflammation, originating from senescent cells. <b>Geriatr Gerontol Int 2024; 24: 845–849</b>.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"24 9","pages":"845-849"},"PeriodicalIF":2.4,"publicationDate":"2024-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ggi.14949","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141888974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mineral supplementation in patients with frailty and sarcopenia—a systematic review","authors":"Masato Ogawa,&nbsp;Yoichi Sato,&nbsp;Fumihiko Nagano,&nbsp;Yoshihiro Yoshimura,&nbsp;Masafumi Kuzuya","doi":"10.1111/ggi.14936","DOIUrl":"10.1111/ggi.14936","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Addressing sarcopenia and frailty in aging populations is crucial for enhancing quality of life and reducing healthcare dependence. While the importance of energy, protein, and amino acid supplementation is known, the role of minerals needs further exploration. This systematic review evaluates the effectiveness of these minerals in managing sarcopenia and frailty.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We analyzed data from the Cochrane Central Register of Controlled Trials, MEDLINE, and Ichu-shi Web from January 2000 to March 2023. Studies were selected if they were interventional or observational, focused on individuals with frailty or sarcopenia who were aged 65 or older, and involved mineral supplementation. The risk of bias in these studies was assessed using the Cochrane Risk of Bias 2 tool.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of the 615 studies identified, seven met the inclusion criteria. These studies mainly focused on the effects of combined nutrient supplements, with few focusing on individual minerals. The findings were mixed, demonstrating some improvements in muscle strength, activity of daily living, and cognitive functions. Notably, minerals appeared to offer benefits as part of multi-nutrient interventions, especially for cognitive and immune health, but had limited impact on muscle mass or strength when used alone. The limited number and variable outcomes of studies precluded a feasible meta-analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The effect of mineral supplementation on sarcopenia and frailty remains uncertain, suggesting a need for tailored nutritional strategies. Future studies should aim for well-designed clinical trials in order to gain a better understanding of the roles of minerals in improving muscle health and functional outcomes, leading to clearer recommendations for clinical practice. <b>Geriatr Gerontol Int 2024; 24: 850–858</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"24 9","pages":"850-858"},"PeriodicalIF":2.4,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ggi.14936","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141874580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between oral frailty and nutritional status among hemodialysis patients aged ≥50 years","authors":"Masanori Iwasaki,&nbsp;Yuko Ohta,&nbsp;Natsuka Furusho,&nbsp;Satoko Kakuta,&nbsp;Kosuke Muraoka,&nbsp;Toshihiro Ansai,&nbsp;Shuji Awano,&nbsp;Masayo Fukuhara,&nbsp;Hidetoshi Nakamura","doi":"10.1111/ggi.14947","DOIUrl":"10.1111/ggi.14947","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Malnutrition is a prevalent health issue among hemodialysis patients. Oral frailty, a condition characterized by impairments in multiple oral health aspects and functions, has been associated with nutritional status in the general population. We aimed to determine whether oral frailty was associated with nutritional status in hemodialysis patients aged ≥50 years. Our secondary aim was to determine the prevalence of oral frailty in this population.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This cross-sectional study included hemodialysis patients who were admitted to a single medical center. According to the Oral Frailty 5-item Checklist, oral frailty is characterized by the presence of two or more of the following criteria: (i) fewer teeth, (ii) difficulty in chewing, (iii) difficulty in swallowing, (iv) dry mouth, and (v) low articulatory oral motor skills. Patients' nutritional status was assessed using the Geriatric Nutritional Risk Index (GNRI). Multivariable ordinal logistic regression analysis was performed to assess the association between oral frailty and nutritional status (classified into three categories according to the GNRI: &gt;98, 92–98, and &lt;92).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In total, 152 hemodialysis patients (55 women and 97 men) with a mean age of 70.4 years were included. The prevalence of oral frailty was 61.2%. After adjusting for health characteristics and sociodemographic background, oral frailty was associated with poor nutritional status according to the GNRI (odds ratio = 2.04, 95% confidence interval = 1.02–4.09).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>In this study, approximately 60% of hemodialysis patients aged ≥50 years exhibited oral frailty, and hemodialysis patients with oral frailty had poor nutritional status according to the GNRI. <b>Geriatr Gerontol Int 2024; 24: 891–897</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"24 9","pages":"891-897"},"PeriodicalIF":2.4,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141874578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between serum vitamin D levels and skeletal muscle indices in an older Japanese population: The SONIC study","authors":"Yuri Onishi,&nbsp;Hiroshi Akasaka,&nbsp;Kodai Hatta,&nbsp;Ken Terashima,&nbsp;Shino Yoshida,&nbsp;Yukiko Yasunobe,&nbsp;Taku Fujimoto,&nbsp;Masaaki Isaka,&nbsp;Kayo Godai,&nbsp;Michiko Kido,&nbsp;Mai Kabayama,&nbsp;Ken Sugimoto,&nbsp;Yukie Masui,&nbsp;Kiyoaki Matsumoto,&nbsp;Saori Yasumoto,&nbsp;Madoka Ogawa,&nbsp;Takeshi Nakagawa,&nbsp;Yasumichi Arai,&nbsp;Tatsuro Ishizaki,&nbsp;Yasuyuki Gondo,&nbsp;Kazunori Ikebe,&nbsp;Kei Kamide,&nbsp;Koichi Yamamoto","doi":"10.1111/ggi.14951","DOIUrl":"10.1111/ggi.14951","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Vitamin D (VD) affects skeletal muscles. The high prevalence of VD deficiency in Japan may lead to decreased skeletal muscle mass and strength, increasing the prevalence of sarcopenia. Therefore, we aimed to investigate the association between serum VD levels and skeletal muscle indices in a Japanese community-dwelling older population.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We extracted data from the Septuagenarians, Octogenarians, Nonagenarians Investigation with Centenarians (SONIC) study. We analyzed the data for participants in the 70s and 90s age groups. Skeletal mass index (SMI) using bioimpedance analysis, grip strength, walking speed, and serum VD levels using 25-hydroxyvitamin D [25(OH)D] were measured.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>We analyzed the data of 310 participants in their 70s and 48 in their 90s. Mean serum 25(OH)D levels were 21.6 ± 5.0 ng/mL in the 70s group and 23.4 ± 9.1 ng/mL in the 90s group. In the 70s group, serum 25(OH)D levels correlated with SMI (<i>r</i> = 0.21, <i>P</i> &lt; 0.0001) and grip strength (<i>r</i> = 0.30, <i>P</i> &lt; 0.0001). Serum 25(OH)D levels were independently associated with SMI after adjusting for sex, body mass index, and serum albumin levels. In the 90s group, serum 25(OH)D levels were correlated with SMI (<i>r</i> = 0.29, <i>P</i> = 0.049) and grip strength (<i>r</i> = 0.34, <i>P</i> = 0.018). However, the multivariate analysis showed no independent association between SMI, grip strength, and serum 25(OH)D levels.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>In a cross-sectional analysis of an older population, serum VD levels were associated with SMI and grip strength, and this association was more pronounced in the 70s group than in the 90s group. Our results suggest that serum VD levels maintain skeletal muscle mass and grip strength. <b>Geriatr Gerontol Int 2024; 24: 898–903</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"24 9","pages":"898-903"},"PeriodicalIF":2.4,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ggi.14951","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141874579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Last year of life care transitions between long-term care insurance services in Japan: Analysis of long-term care insurance claims data","authors":"Masayo Kashiwagi,&nbsp;Kimikazu Kashiwagi,&nbsp;Noriko Morioka,&nbsp;Kazuhiro Abe","doi":"10.1111/ggi.14944","DOIUrl":"10.1111/ggi.14944","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>We determined the number of care transitions in the year before death among older adults requiring long-term care (LTC) and those receiving public LTC insurance (LTCI) services in Japan, along with care transition pathways and factors associated with the number of care transitions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This study used data from the Japanese LTCI claims, which store national information on certification of needed LTC and LTCI claims data. Services received in the year before death were classified as in-home, facility, mixture of in-home and facility, and not using LTCI services. The transition count is presented, and Sankey diagrams are produced to visualize care transition pathways. We used a multivariable analysis to identify factors associated with the number of care transitions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of the participants, 276 896 (65.2%) experienced at least one transition in LTCI care settings in the year before death. Further, 72.0% of those requiring mild LTC underwent one or more transitions. Participants who were 75–84 years old (vs. 65–74 years old), male, without medical care needs, with symptoms of dementia, and with changes in LTC needs in the year before death were more likely to require care transitions. Moreover, participants with higher baseline LTC needs were less likely to require transitions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Over half the participants requiring LTC underwent one or more care transitions in the year before death. Policy deliberations regarding enhancing care under the LTCI system at the end of life and optimizing care transitions are necessary. <b>Geriatr Gerontol Int 2024; 24: 883–890</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"24 9","pages":"883-890"},"PeriodicalIF":2.4,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ggi.14944","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141855328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}