Geriatrics & Gerontology International最新文献

{"title":"Association of personality and social support with subjective well-being among Japanese older adults.","authors":"Hajime Iwasa, Hiroki Inagaki, Yukie Masui, Yasuyuki Gondo","doi":"10.1111/ggi.15043","DOIUrl":"https://doi.org/10.1111/ggi.15043","url":null,"abstract":"<p><strong>Aim: </strong>Although the association between personality and health has been well documented, the interaction between personality and health risk factors is understudied. This study examined (i) the relationship between the Big Five model of personality and subjective well-being and (ii) the buffering effect of social support on the relationship between personality and subjective well-being among Japanese older adults.</p><p><strong>Methods: </strong>The participants were 1265 adults aged 65-84 (499 men, 766 women). The Philadelphia Geriatric Center Morale Scale was used as an index of subjective well-being (the study outcome). As explanatory variables, the Japanese version of the NEO-Five Factor Inventory measured the five domains of personality traits, and the Multidimensional Scale of Perceived Social Support measured social support. Data on age, sex, years of education, living arrangements (living alone or with family), psychiatric problems, chronic illness, and instrumental activities of daily living dependence, which were used as covariates, were obtained to test the independent association of personality and social support with subjective well-being.</p><p><strong>Results: </strong>The multivariable regression analysis showed that neuroticism (β = -0.543), extraversion (β = 0.167), agreeableness (β = -0.099), social support (β = 0.143), and the interaction between social support and neuroticism (β = 0.058) were significantly associated with subjective well-being.</p><p><strong>Conclusions: </strong>Our findings show that social support moderates the association between neuroticism and subjective well-being among older adults. Accordingly, for older adults who are higher in neuroticism, interventions that provide increased social support may help reduce the risk of poorer well-being. Geriatr Gerontol Int 2024; ••: ••-••.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142835101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying determinants of physical activity in older patients with musculoskeletal disorders undergoing rehabilitation: Comparison of two distinct models using structural equation modeling.","authors":"Masashi Kanai, Kazuki Yoshida, Hiroki Okada, Takuro Ohtsubo, Katsuhiro Ueno, Masafumi Nozoe","doi":"10.1111/ggi.15022","DOIUrl":"https://doi.org/10.1111/ggi.15022","url":null,"abstract":"<p><strong>Aim: </strong>Mobility restrictions cause older adults with musculoskeletal disorders to have lower levels of physical activity. However, the determinants of their physical activity during hospitalization are unclear. We aimed to compare two conceptual frameworks using structural equation modeling to identify factors influencing physical activity in older patients with musculoskeletal disorders.</p><p><strong>Methods: </strong>This cross-sectional study included older patients with musculoskeletal disorders at a single convalescent rehabilitation hospital. Physical activity was objectively measured using a triaxial accelerometer. We utilized structural equation modeling to contrast two conceptual frameworks: (i) the sarcopenia/nutrition/activities of daily living model, and (ii) the age-related deconditioning/activities of daily living model. The models' goodness-of-fit was evaluated, including root mean square approximation error, goodness-of-fit index (GFI), adjusted GFI and Akaike information criterion.</p><p><strong>Results: </strong>We enrolled 274 older patients (age 78.0 years; 42 men, 232 women) with musculoskeletal disorders. Among them, 123 (44.9%) were diagnosed with sarcopenia and 69 (25.2%) with malnutrition. The goodness-of-fit of the (ii) model (root mean square approximation error = 0.068, GFI = 0.958, adjusted GFI = 0.909, Akaike information criterion = 5780.875) was superior to the (i) model (root mean square approximation error = 0.080, GFI = 0.953, adjusted GFI = 0.887, Akaike information criterion = 5791.429).</p><p><strong>Conclusions: </strong>We discovered that the age-related deconditioning/activities of daily living model effectively explained physical activity in hospitalized older patients with musculoskeletal disorders. A comprehensive approach considering age-related changes, such as sarcopenia and malnutrition, might offer a simpler and more effective framework for understanding and promoting physical activity in this demographic. Geriatr Gerontol Int 2024; ••: ••-••.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142828021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between the number of remaining teeth and postoperative delirium in patients after gastrointestinal surgery.","authors":"Nanako Kawata, Mitsuyoshi Yoshida, Ayu Sakai, Tsuyoshi Tanaka, Gaku Inaguma, Koichi Suda, Akitsugu Ohuchi","doi":"10.1111/ggi.15047","DOIUrl":"https://doi.org/10.1111/ggi.15047","url":null,"abstract":"<p><strong>Aim: </strong>Malnutrition is reportedly associated with the development of delirium. As dental health is essential for nutritional intake, tooth loss may be a risk factor for the development of delirium. This study aimed to investigate the relationship between postoperative delirium and the number of remaining teeth in patients undergoing gastrointestinal surgery.</p><p><strong>Methods: </strong>This retrospective study included 453 consecutive patients aged ≥65 years who underwent programmed gastrointestinal cancer surgery under general anesthesia at the Department of Surgery, Fujita Health University Hospital, between January 2022 and December 2022. Background factors were prepared between the participants with and without dental intervention. In the dental intervention group, associations between background and surgical factors and the presence of postoperative delirium were explored. Factors with significant associations with postoperative delirium in the univariate analysis were subjected to logistic regression analysis to determine their association with the number of remaining teeth.</p><p><strong>Results: </strong>Overall, 189 participants underwent postoperative management. They had a significantly lower Prognostic Nutritional Index and higher cognitive decline than the 264 patients who underwent no dental intervention during this period. However, no significant difference was observed in the incidence of postoperative delirium between the two groups. In the dental intervention group, logistic regression analyses revealed that postoperative complications and the number of remaining teeth were significantly associated with postoperative delirium development.</p><p><strong>Conclusion: </strong>The results revealed that a decrease in the number of remaining teeth is associated with postoperative delirium. The cause of this is not clear, but it is thought to be related to brain fragility. Geriatr Gerontol Int 2024; ••: ••-••.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142823751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of high blood pressure on the risk of mortality among Japanese people aged 65 years and older.","authors":"Shinsuke Akagi, Soshi Takao, Rumi Matsuo, Naomi Matsumoto, Takashi Yorifuji","doi":"10.1111/ggi.15046","DOIUrl":"https://doi.org/10.1111/ggi.15046","url":null,"abstract":"<p><strong>Aim: </strong>The purpose of this study is to investigate the impact of abnormal blood pressure on the risk of all-cause and cardiovascular mortality in a large cohort of older Japanese people aged ≥65 years.</p><p><strong>Methods: </strong>This cohort study enrolled 54 760 participants from Okayama City aged ≥65 years who underwent basic health checkups from April 2006 to March 2008. Based on blood pressure, the participants were divided into six categories, from C1 (lowest) to C6 (highest). To assess the association of blood pressure with all-cause and cardiovascular mortality, we used survival analysis to estimate hazard ratios (HRs) for all-cause mortality and subdistribution HRs (SHRs) for cardiovascular mortality on C3. We then repeated the analyses based on age groups (65-74 years, 75-84 years, and ≥85 years).</p><p><strong>Results: </strong>The fully adjusted HRs for all-cause mortality, which included all individual potential confounders, were 1.11 (95% confidence interval [CI]: 1.04-1.19) for C5 and 1.23 (95% CI: 1.09-1.38) for C6, respectively. The fully adjusted SHRs for cardiovascular mortality were 1.11 (95% CI: 1.01-1.21) for C4, 1.19 (95% CI: 1.05-1.34) for C5, and 1.36 (95% CI: 1.09-1.70) for C6. In the age-stratification, an increased risk of hypotension was observed with older age. The HR for C1 was 1.28 (95% CI: 1.16-1.41) for ≥85 years.</p><p><strong>Conclusions: </strong>Hypertension increased the risk of all-cause and cardiovascular mortality among those aged 65-74 and 75-84 years, but not among those aged ≥85 years. Geriatr Gerontol Int 2024; ••: ••-••.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142812839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on: Association of sleep duration with obesity in older adults: A systematic review and meta-analysis.","authors":"Merve Yilmaz Kars, Mustafa Hakan Dogan, Ilyas Akkar, Zeynep Iclal Turgut, Orhan Cicek, Muhammet Cemal Kizilarslanoglu","doi":"10.1111/ggi.15044","DOIUrl":"https://doi.org/10.1111/ggi.15044","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142812838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Causal association between sarcopenia and cognitive impairment contributes to the muscle-brain axis: A bidirectional Mendelian randomization study.","authors":"Lincheng Duan, Haoming Li, Shiyin Li, Yue Shi, Yue Feng","doi":"10.1111/ggi.15045","DOIUrl":"https://doi.org/10.1111/ggi.15045","url":null,"abstract":"<p><strong>Aim: </strong>There is a growing body of evidence suggesting a correlation between sarcopenia (SP) and cognitive impairment (CI), but with conflict. This study employed a bidirectional Mendelian randomization (MR) approach to ascertain the causality between SP and CI.</p><p><strong>Method: </strong>This study looked at whether there might be causality between SP and CI by using a bidirectional MR analysis on the GWAS summary datasets, which anyone can publicly access. The primary analysis employed inverse variance weighting (IVW), with MR-Egger, weighted median, and mendelian randomization pleiotropy residual sum and outlier (MR-PRESSO) serving as supplements. Multiple sensitivity analyses were performed to enhance the stability of the results, which encompassed heterogeneity tests and pleiotropy tests.</p><p><strong>Results: </strong>Appendicular lean mass (ALM), walking pace (WP), and grip strength (GS) were found to be causally connected to cognitive performance in forward MR analysis. In the reverse MR study, cognitive performance also had a causal impact on ALM and WP. Additionally, we discovered comparable outcomes in the replication samples, which strengthens the validity of our findings.</p><p><strong>Conclusions: </strong>The results of our MR investigation revealed a definitive cause-and-effect association between SP and CI. Our findings provide additional supporting evidence for the muscle-brain axis, which may suggest that muscle strengthening has a significant impact on the management and avoidance of CI. Geriatr Gerontol Int 2024; ••: ••-••.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142806787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Time-course assessment of oral intake function and its impact on end-of-life in older individuals over 90 years with frailty.","authors":"Hidetada Yamada, Masahiro Nakamori, Masaya Oda, Megumi Toko, Hideaki Sakahara, Yuichiro Tagane, Yu Yamazaki, Yuishin Izumi, Hirofumi Maruyama","doi":"10.1111/ggi.15048","DOIUrl":"https://doi.org/10.1111/ggi.15048","url":null,"abstract":"<p><strong>Aim: </strong>The study investigates end-of-life trajectories, focusing on the degree of oral intake function in older individuals with frailty aged over 90 years.</p><p><strong>Methods: </strong>This retrospective observational study examined individuals aged 90 years and older who passed away at a long-term chronic care hospital and related facilities in Japan. We assessed their Clinical Frailty Scale (CFS) and Function Oral Intake Scale (FOIS), categorizing them into two groups-\"preserved CFS\" (CFS score ≤7) and \"poor CFS\" (CFS score ≥8)-considering evaluations conducted 6 months before death. We examined the transitional progression of their CFS and FOIS scores, along with a time-course assessment of low FOIS scores (≤3) in each group at various intervals.</p><p><strong>Results: </strong>Among 66 cases, 38 were in the preserved CFS group, and 28 were in the poor CFS group. The CFS and FOIS scores of the preserved CFS group declined rapidly towards the end-of-life, with approximately half experiencing significant declines within 3 months. In contrast, both the CFS and the FOIS scores of the poor CFS group declined gradually within 6 months. The percentage of low FOIS score (≤3) was lower at 12 and 6 months than at 1 month prior to death in the preserved CFS group.</p><p><strong>Conclusions: </strong>The end-of-life trajectories in older individuals with frailty aged over 90 years were heterogeneous. Clinicians should carefully monitor the degree of frailty and changes in food intake as crucial indications of the end-of-life phase, providing optimal support to manage potential vicious cycles. Geriatr Gerontol Int 2024; ••: ••-••.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142806806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for post-endoscopic retrograde cholangiopancreatography complications in very elderly patients aged 90 years or older-No additional risk.","authors":"Daisuke Manabe, Toshihiko Arizumi, Hitoshi Aoyagi, Koichiro Abe, Shinya Kodashima, Yoshinari Asaoka, Takatsugu Yamamoto, Atsushi Tanaka","doi":"10.1111/ggi.15037","DOIUrl":"https://doi.org/10.1111/ggi.15037","url":null,"abstract":"<p><strong>Aim: </strong>In recent years, the majority of patients eligible for endoscopic retrograde cholangiopancreatography (ERCP) have been aged ≥75 years. We investigated ERCP safety in very elderly patients (aged ≥90 years).</p><p><strong>Methods: </strong>We included patients aged ≥75 years who underwent ERCP between January 2015 and December 2020. We compared background factors, comorbidities, ERCP indications, complications, and outcomes and identified risk factors for complications using binary logistic regression and inverse probability of treatment weighting with propensity scores.</p><p><strong>Results: </strong>The study included 1344 patients aged ≥75 years (137 and 1207 very elderly and elderly patients, respectively). The very elderly group had more women, less frequent diabetes, fewer antithrombotic medications, more frequent parapapillary diverticulum, less frequent post-cholecystectomy, and worse performance status. No significant differences were observed in the ERCP indications. Experienced endoscopists were likely to perform the procedure, and the procedure time was shorter for the very elderly. Complications occurred in 21 (15%) very elderly patients and 120 (10%) elderly patients, with no significant differences. The very elderly did not have an increased risk of complications but were less likely to be discharged home and had a significantly worse performance status at discharge.</p><p><strong>Conclusions: </strong>ERCP could be safely performed in the very elderly, and age did not increase the risk of complications. Geriatr Gerontol Int 2024; ••: ••-••.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142806799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PRISMA-7 is a predictor of intensive care unit admission and mortality in older patients in an emergency department.","authors":"Şimşek Çelik, Onur Türkdoğan, Tayfun Erdoğan, Pelin Çelik","doi":"10.1111/ggi.15039","DOIUrl":"https://doi.org/10.1111/ggi.15039","url":null,"abstract":"<p><strong>Aim: </strong>To compare the performance of the Programme of Research on the Integration of Services for the Maintenance of Autonomy (PRISMA-7), which is used to assess the frailty of older patients visiting emergency departments, with the quick Sepsis Related Organ Failure Assessment (qSOFA) and Emergency Severity Index (ESI) in terms of 28-day mortality and intensive care unit (ICU) admission.</p><p><strong>Methods: </strong>This study was prospective and observational. All patients above the age of 65 who were admitted to the Sivas Republic University Medical Faculty Hospital from March 1 to April 30 in the year 2024 were included in the study. Patients' all-cause mortality values and ICU acceptance rates were evaluated for a 28-day period following their applications.</p><p><strong>Results: </strong>The area under the receiver operating characteristic curve stood for the 28-day mortality, while the values for PRISMA-7, ESI, and qSOFA were, respectively, 0.81 (95% confidence interval [CI]: 0.78-0.84), 0.78 (95% CI: 0.72-0.83), and 0.71 (95% CI: 0.65-0.77). Our findings have demonstrated PRISMA-7 to be more effective than ESI and qSOFA in terms of hospitalization predictions. However, while it was found to be more effective than qSOFA in mortality predictions, it was determined that, despite PRISMA-7 having a larger AUC than ESI, no meaningful difference existed between PRISMA-7 and ESI.</p><p><strong>Conclusions: </strong>In conclusion, PRISMA-7, which is thought of as a reliable and valid tool for the determination of frailty in emergency departments, has predictive value for individuals' 28-day mortality risk as well as for their acceptance to the ICU. Geriatr Gerontol Int ••; ••: ••-•• Geriatr Gerontol Int 2024; ••: ••-••.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of oral health care intervention for stroke patients following the introduction of Oral Health Assessment Tool.","authors":"Kazuyuki Matsunaga, Ayaka Yoshida-Tsuboi, Ken Inohara, Yasuko Yoshida, Kanako Nakahama, Kazuki Sasaki, Fumie Souda, Yuka Terasawa, Yutaka Shimoe, Kazu Takeuchi-Hatanaka, Tadashi Yamamoto, Kazuhiro Omori, Tatsuo Kohriyama, Shogo Takashiba","doi":"10.1111/ggi.15035","DOIUrl":"https://doi.org/10.1111/ggi.15035","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to evaluate the effectiveness of oral health assessment tools in facilitating oral health care interventions by dental care providers for acute stroke patients within 48 h of admission, following a reform of the nursing system.</p><p><strong>Methods: </strong>Data were gathered from a retrospective cohort study conducted at a stroke center, comparing 10 months before and after the implementation of the reformed system, with a 2-month interval. Parameters assessed included stroke type, severity measured using the National Institutes of Health Stroke Scale, stroke history, stroke-related factors, number of teeth, hospitalization cost and duration, occurrence of fever and pneumonia, stroke treatment, days from admission to dental intervention, and intervention frequency.</p><p><strong>Results: </strong>Implementation of the new system significantly reduced the time before dental intervention (P < 0.001), increased the frequency of interventions (P < 0.001), and allowed for the management of more severe cases (P = 0.007). However, there was a slight increase in the occurrence of fevers and the days of fever (P = 0.039 and P = 0.015, respectively). Multiple regression analysis showed that fever days were positively correlated with stroke severity and the number of days from admission to dental intervention (P < 0.001 and P = 0.013, respectively). Even after propensity score matching adjusting for stroke severity, these associations persisted. Additional multiple regression analysis was performed after this, but fever days were positively correlated with stroke severity and sex (P < 0.001 and P = 0.008, respectively), as well as with the presence of other factors affecting the occurrence of fever.</p><p><strong>Conclusions: </strong>Although the frequency and duration of fevers increased slightly, this approach, incorporating oral health assessment tools, made it possible to provide early dental intervention, particularly for patients with severe strokes. Geriatr Gerontol Int 2024; ••: ••-••.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}