{"title":"Late-onset primary muscle diseases mimicking sarcopenia","authors":"Satoshi Yamashita","doi":"10.1111/ggi.15000","DOIUrl":"10.1111/ggi.15000","url":null,"abstract":"<p>Sarcopenia is an age-related loss of skeletal muscle mass, strength, and function that causes various health problems. In contrast, late-onset primary myopathies, which occur in the older population, are caused by a variety of factors, including genetic mutations, autoimmune processes, and metabolic abnormalities. Although sarcopenia and primary myopathy are two distinct disease processes, their symptoms can overlap, making differentiation challenging. The diagnostic criteria for sarcopenia have evolved over time, and various criteria have been proposed by expert groups. Late-onset primary muscle diseases such as inclusion body myositis, sporadic late-onset nemaline myopathy, muscular dystrophies, distal myopathies, myofibrillar myopathies, metabolic myopathies, and mitochondrial myopathies share common pathogenic mechanisms with sarcopenia, further complicating the diagnostic process. Appropriate clinical evaluation, including detailed history-taking, physical examination, and diagnostic testing, is essential for accurate diagnosis and management. Treatment approaches, including exercise, nutritional support, and disease-specific therapies, must be tailored to the characteristics of each disease. Despite these differences, sarcopenia and primary myopathies require careful consideration in the clinical setting for proper diagnosis and management. This review outlines the evolution of diagnostic criteria and diagnostic items for sarcopenia, late-onset primary myopathies that should be differentiated from sarcopenia, common pathomechanisms, and diagnostic algorithms to properly differentiate primary myopathies. <b>Geriatr Gerontol Int 2024; 24: 1099–1110</b>.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142462643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study protocol of the safe driving program for the prevention of car accidents: A randomized controlled trial protocol","authors":"Hiroyuki Shimada, Hideaki Ishii, Takehiko Doi, Kota Tsutsumimoto, Sho Nakakubo, Satoshi Kurita, Hidenori Arai","doi":"10.1111/ggi.14989","DOIUrl":"10.1111/ggi.14989","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Driving cessation is strongly associated with adverse health outcomes in older adults. Although numerous studies have focused on driving skill interventions for safe driving, the effects of interventions on car accidents remain unclear. We designed a randomized controlled trial to examine the effects of driving skill training on the prevention of car accidents among community-dwelling older adults using on-road training.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A total of 1408 community-dwelling older drivers aged ≥65 years participated in the randomized controlled trial with blinded endpoint assessment. Participants randomized to the intervention group (<i>n</i> = 697) underwent four sessions, with 200 min re-training focused on the problem of driving in the older people. Controls (<i>n</i> = 697) received one classroom education session. On-road driving performance was assessed by certified driving school instructors in a driving school. The primary endpoint is an incident car accident, which will be detected based on the Japanese national car accident report data, after 24 months.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>This study has the potential to provide the first evidence of the effectiveness of on-road driving skill training regarding the prevention of car accidents. If our trial results show a lower number of car accidents due to driving skill training, this kind of intervention will provide an effective method for maintaining safe driving. These results will be disseminated to the appropriate national transportation agencies to improve or modify safe driving policies and possibly extend the validity of driver's licenses for older adults.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p>UMIN-CTR (identification number: UMIN000034709). Registered 31 October 2018. <b>Geriatr Gerontol Int 2024; 24: 1218–1222</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142462646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Suguru Shimokihara, Hiroyuki Tanaka, Walter R Boot, Yuma Nagata, Shunsuke Nakai, Masahiro Tenjin, Takayuki Tabira
{"title":"Development of the Japanese version of the Mobile Device Proficiency Questionnaire: A cross-sectional validation study","authors":"Suguru Shimokihara, Hiroyuki Tanaka, Walter R Boot, Yuma Nagata, Shunsuke Nakai, Masahiro Tenjin, Takayuki Tabira","doi":"10.1111/ggi.14994","DOIUrl":"10.1111/ggi.14994","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>In response to the growing popularity of mobile devices among older adults in Japan, this study aimed to establish a reliable and valid measure of mobile device proficiency by developing a Japanese version of the Mobile Device Proficiency Questionnaire (MDPQ-J) for the Japanese population.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>To evaluate the reliability and validity of the MDPQ-J, we administered the questionnaire to 100 young or middle-aged participants (37.78 ± 13.90 years, 57.00% women), and 62 older participants (75.90 ± 6.01 years; 59.68% women).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The MDPQ-J showed a high degree of internal consistency (Cronbach's α = 0.98). Moreover, MDPQ-J scores in older participants tended to be lower than those in young or middle-aged participants. In terms of validity, the MDPQ-J score of older participants was significantly associated with age (ρ = −0.31), the amount of time using a mobile device per day (ρ = 0.64), and the system usability scale (ρ = 0.39). Additionally, the MDPQ-J scores were significantly positively associated with the importance (ρ = 0.37), performance (ρ = 0.57), and satisfaction (ρ = 0.29) associated with daily mobile device use in older participants.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The high reliability and validity of the MDPQ-J in the Japanese population highlight its utility in adapting mobile devices for older adults, which is crucial in an increasingly digital society. Further research should explore the mediating role of mobile device proficiency in various health-related outcomes. <b>Geriatr Gerontol Int 2024; 24: 1223–1232</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ggi.14994","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142389589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Characteristics of falls in Japanese community-dwelling older adults","authors":"Minoru Yamada, Yusuke Terao, Iwao Kojima, Shu Tanaka, Hiroki Saegusa, Miho Nanbu, Shiho Soma, Hiroki Matsumoto, Masaya Saito, Kohei Okawa, Naoto Haga, Hidenori Arai","doi":"10.1111/ggi.14995","DOIUrl":"10.1111/ggi.14995","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Understanding the characteristics of falls among older adults is necessary to prevent them. These characteristics include questions such as when (month and time), where (places), who (age), what (injury), why (trigger), and how (direction) the falls occur. The objective of this study was to identify the characteristics of falls in individuals aged 65–74 years (young-old), 75–84 years (old-old), and ≥85 years (oldest-old).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We conducted an observational mail survey among community-dwelling older adults in Japan and collected detailed information on the incidence of falls over the past 3 years. The month, time, location, trigger, direction, and resulting trauma of each fall were analyzed and compared across the different age groups (young-old, old-old, and oldest-old).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 1695 falls among 1074 community-dwelling older adults were analyzed in this study. Falls were frequent during May and October as well as during the winter season from December to February, especially between 10:00 a.m. and 11:00 a.m. These fall characteristics were consistent across all the age groups. There was a higher incidence of outdoor falls among relatively young older adults, which were typically caused by tripping or slipping. However, as one progresses with age, there is a higher incidence of falls indoors, typically due to loss of balance or leg entrapment. Approximately 60% of older fallers experience some form of injury due to falls, with fractures considered the most serious, occurring in ≈10% of all falls.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>We clarified the characteristics of falls including the “when, where, who, what, why, and how” of the fall. A future challenge is to use this valuable information to develop effective fall prevention programs for older populations worldwide. <b>Geriatr Gerontol Int 2024; 24: 1181–1188</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142389586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sandra Cuerpo, Sira Aguiló, Aitor Alquézar-Arbé, Cesáreo Fernández, Guillermo Burillo, Javier Jacob, Francisco Javier Montero-Pérez, Eric Jorge García-Lamberechts, Pascual Piñera, Beatriz Escudero Blázquez, Cristina Güemes de la Iglesia, Sílvia Flores Quesada, Aarati Vaswani-Bulchand, Montserrat Rodríguez-Cabrera, Paula Lázaro Aragüés, María Luisa Pérez Díaz-Guerra, Francesc Xavier Alemany González, Ana Puche Alcaraz, Jésica Mansilla Collado, Gema Jara Torres, Lidia Fuentes, Rocío Muñoz Martos, Antonio Real López, Rodrigo Javier Gil Hernández, Jorge Pedraza García, Esperanza Muñoz Trian, Juan González del Castillo, Òscar Miró, the members of the SIESTA network
{"title":"Tachypnea in response to hypoxemia decreases with age in older patients","authors":"Sandra Cuerpo, Sira Aguiló, Aitor Alquézar-Arbé, Cesáreo Fernández, Guillermo Burillo, Javier Jacob, Francisco Javier Montero-Pérez, Eric Jorge García-Lamberechts, Pascual Piñera, Beatriz Escudero Blázquez, Cristina Güemes de la Iglesia, Sílvia Flores Quesada, Aarati Vaswani-Bulchand, Montserrat Rodríguez-Cabrera, Paula Lázaro Aragüés, María Luisa Pérez Díaz-Guerra, Francesc Xavier Alemany González, Ana Puche Alcaraz, Jésica Mansilla Collado, Gema Jara Torres, Lidia Fuentes, Rocío Muñoz Martos, Antonio Real López, Rodrigo Javier Gil Hernández, Jorge Pedraza García, Esperanza Muñoz Trian, Juan González del Castillo, Òscar Miró, the members of the SIESTA network","doi":"10.1111/ggi.14965","DOIUrl":"10.1111/ggi.14965","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To investigate if tachypneic response to hypoxia is decreased in older patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We included all patients ≥65 years of age attending 52 Spanish emergency departments (EDs) for whom peripheral arterial oxygen saturation (SatO<sub>2</sub>) measured by pulsioxymetry and respiratory rate (RR) were registered at ED arrival. We assessed the relationship between SatO2 and RR in different models, and with the best-fitting model, we independently analyzed this relationship in four subgroups according to patient age (65–69, 70–79, 80–89, and ≥90 years). Five sensitivity analyses using different subsets of patients were carried out to check for the consistency of the results.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>We included 7126 patients, with medians for SatO<sub>2</sub> and RR of 97% (interquartile range [IQR]: 94–98) and 15 bpm (IQR: 15–16), respectively. We found significant associations (<i>P</i> < 0.001) between SatO<sub>2</sub> and RR in every model tested (<i>P</i> < 0.001 for all), with the quadratic model obtaining the best fit (R<sup>2</sup>: 0.098) over those obtained with linear (R<sup>2</sup>: 0.096) and logarithmic (R<sup>2</sup>: 0.092) models. The same was observed in sensitivity analyses, with R<sup>2</sup> for quadratic models ranging from 0.069 in patients with low comorbidity and 0.102 in patients breathing room air. The mean RR for 100% SatO<sub>2</sub> was 15 bpm and increased as SatO<sub>2</sub> decreased, although with a progressive slowing of the slope, with a mean RR of 27 at 50% SatO<sub>2</sub>. We detected a decreased RR response to increasing hypoxemia according to age and, while the RR curve was higher and with a progressively steepening slope in the 972 patients aged 65–69 (mean RR of 42 bpm with 50% SatO<sub>2</sub>), a progressive slowing of slope was observed in the 2693 patients aged 70–79 (mean RR of 28 with 50% SatO2), the 2582 aged 80–89 (mean RR of 25) and the 879 aged ≥90 (mean RR of 23). Sensitivity analyses provided very similar results.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Tachypneic response to hypoxemia in older patients decreases as age advances, regardless of the reason leading to hypoxemia. <b>Geriatr Gerontol Int 2024; 24: 1120–1129</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142389592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Consensus statement on “Oral frailty” from the Japan Geriatrics Society, the Japanese Society of Gerodontology, and the Japanese Association on Sarcopenia and Frailty","authors":"Tomoki Tanaka, Hirohiko Hirano, Kazunori Ikebe, Takayuki Ueda, Masanori Iwasaki, Shunsuke Minakuchi, Hidenori Arai, Masahiro Akishita, Koichi Kozaki, Katsuya Iijima","doi":"10.1111/ggi.14980","DOIUrl":"10.1111/ggi.14980","url":null,"abstract":"<p>The concept of oral frailty was first proposed in Japan in 2014 by the “Joint Working Committee on Oral Frailty,” consisting of three academic societies—the Japan Geriatrics Society, the Japanese Society of Gerodontology, and the Japanese Association on Sarcopenia and Frailty—to enhance public understanding of oral frailty. Oral frailty is a state between robust oral function (a “healthy mouth”) and its decline, characterized by slight declines in oral function, including tooth loss and difficulties in eating and communicating, which increase the risk of impaired oral functional capacity but can be reversed with proper intervention and treatment. Oral frailty can be assessed using the Oral Frailty 5-item Checklist (OF-5) without the need for a dental health professional. Oral frailty is defined as having at least two of the following components: (i) fewer teeth, (ii) difficulty chewing, (iii) difficulty swallowing, (iv) dry mouth, and (v) low articulatory oral motor skills. Approximately 40% of community-dwelling older adults have oral frailty. Oral frailty is associated with poor dietary variety, social isolation, physical frailty, disability, and mortality. This statement introduces the concept and definition of oral frailty, a new assessment tool (OF-5), and concept diagrams for healthcare professionals and the general public. These tools aim to promote public awareness and facilitate collaboration between medical and dental healthcare providers. <b>Geriatr Gerontol Int 2024; 24: 1111–1119</b>.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ggi.14980","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142389587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Associations between multimorbidity patterns and sarcopenia transitions in Chinese older adults","authors":"Lingxiao He, Shujing Lin, Jinzhu Yang, Ya Fang","doi":"10.1111/ggi.14984","DOIUrl":"10.1111/ggi.14984","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Previous studies have shown that chronic diseases are strongly linked to the development of sarcopenia. Few studies have assessed the relationship between multimorbidity patterns and sarcopenia. This study aimed to investigate the impact of multimorbidity patterns on sarcopenia transitions in Chinese older adults.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A total of 3842 older adults (aged 66.7 ± 6.2 years) with complete data at baseline and at least one follow-up record (2 years) were included from the China Health and Retirement Longitudinal Study. Multimorbidity patterns were identified using latent class analysis. Sarcopenia was determined by the Asian Working Group for Sarcopenia 2019 criteria. Multistage Markov modeling was used to explore the association of multimorbidity patterns with sarcopenia transitions after controlling for covariates in demographic features, health status and health-related behaviours.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Four multimorbidity patterns were identified at baseline: respiratory (17.73%), osteoarthritis-hypertension (22.23%), digestive-osteoarthritis (26.78) and cardiometabolic (33.27%). Participants with non-sarcopenia had 1-year transition probability of developing possible sarcopenia (10.1%) or sarcopenia (5.4%). Compared with the group without chronic diseases, the presence of cardiometabolic pattern increased the risk of progression from non-sarcopenia to possible sarcopenia (HR 1.43, 95% CI 1.05–2.95). The presence of the osteoarthritis-hypertension pattern (HR 1.55, 95% CI 1.00–2.41) and the digestive-osteoarthritis pattern (HR 1.78, 95% CI 1.20–2.66) were associated with the transition toward sarcopenia from non-sarcopenia.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Sarcopenia is a dynamic condition in older adults. To address sarcopenia in older adults, tailored interventions should be targeted at populations with different multimorbidity patterns. <b>Geriatr Gerontol Int 2024; 24: 1137–1143</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142389585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cross-sectional study of the optimal types of physical exercise for cognitive function in older Japanese adults","authors":"Koki Nagata, Kyohei Shibuya, Yuya Fujii, Jaehoon Seol, Takashi Jindo, Tomohiro Okura","doi":"10.1111/ggi.14991","DOIUrl":"10.1111/ggi.14991","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>This study aimed to determine whether practicing coordination exercises, compared with other physical exercise types, is associated with better cognitive function in older Japanese adults.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This cross-sectional study used data from a health checkup project carried out from 2015 to 2019 among older adults living in Kasama City, Ibaraki Prefecture, Japan. Data from 569 participants (mean age 74.0 ± 5.4 years, 53.8% women) were analyzed. The types of physical exercise practiced within the seven preceding days were identified. The Five-Cog test and Trail Making Test were used to evaluate general cognitive function and executive function, respectively. The cognitive functions of practitioners and non-practitioners of each type of physical exercise – coordination, endurance, resistance, and stretching – were examined using an analysis of covariance.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Although practitioners of any physical exercise did not have significantly better cognitive function than non-practitioners, in an analysis stratified by exercise amount, those who practiced more coordination exercise had better general cognitive function than non-practitioners (<i>P</i> = 0.046), in a fully adjusted model.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Those who practiced more coordination exercises had better general cognitive function. <b>Geriatr Gerontol Int 2024; 24: 1173–1180</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142389588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between physical activity levels and mortality across adiposity: A longitudinal study of age-specific Asian populations","authors":"Yunmin Han, Younghwan Choi, Yeon Soo Kim","doi":"10.1111/ggi.14987","DOIUrl":"10.1111/ggi.14987","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>This study investigated the association of physical activity (PA) levels with all-cause and cardiovascular disease (CVD) mortality risks stratified by adiposity and age.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Participants (36 703; mean age: 49.1; 57.1% women) were selected from the Korea National Health and Nutrition Examination Survey 2007–2013. A Cox proportional hazards model was used to examine the association between PA and mortality across different adiposity categories and ages.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Median follow-up was 9.22 years; 2393 individuals died, including 538 with CVD. Compared with normal-weight controls, underweight individuals had increased all-cause mortality risk (hazard ratio [HR]: 1.60, 95% confidence interval [CI]: 1.33–1.79). The overweight and obese groups demonstrated reduced mortality risks (HRs: 0.75 [95% CI: 0.67–0.84] and 0.59 [95% CI: 0.51–0.67], respectively). Mortality risk based on abdominal obesity had an HR of 1.22 (95% CI: 1.08–1.37). PA protected against mortality risk most in the obese group performing more than 1000 MET-min/week and was particularly significant among those who were underweight and obese aged 65 and older.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Overweight and obese Asian individuals (based on body mass index) had a lower mortality risk than those with normal body mass index, whereas obesity based on waist circumference was associated with increased mortality. PA protected against mortality across various weight categories, especially in individuals aged ≥65. <b>Geriatr Gerontol Int 2024; 24: 1156–1164</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ggi.14987","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142365015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}