Geriatrics & Gerontology International最新文献

{"title":"Clinical Features of Hyperpolypharmacy in Older Patients With Degenerative Cervical Myelopathy.","authors":"Hiroki Takeda, Takao Tobe, Takehiro Michikawa, Takaya Imai, Yuki Akaike, Soya Kawabata, Sota Nagai, Shinjiro Kaneko, Shigeki Yamada, Nobuyuki Fujita","doi":"10.1111/ggi.70194","DOIUrl":"https://doi.org/10.1111/ggi.70194","url":null,"abstract":"<p><strong>Aims: </strong>Polypharmacy, hyperpolypharmacy, and potentially inappropriate medication (PIM) in older adults are growing health concerns in the aging population. Older patients with degenerative cervical myelopathy (DCM) often have multiple comorbidities and are prescribed numerous medications. Thus, we investigated the current status of medication use among older patients with DCM, identified the characteristics of those with hyperpolypharmacy, and evaluated its impact on postoperative outcomes.</p><p><strong>Methods: </strong>This retrospective study included 130 older patients with surgery for DCM. All participants completed the Japanese Orthopaedic Association Cervical Myelopathy Evaluation Questionnaire (JOACMEQ) before and 1 year after surgery.</p><p><strong>Results: </strong>Forty-two patients had hyperpolypharmacy (H group), and 88 had non-hyperpolypharmacy (N group). The commonly prescribed PIMs were antidiabetics (24.6%), nonsteroidal anti-inflammatory drugs (21.5%), and hypnotics (20.8%). Hypnotic use was significantly higher in the H group than in the N group (p < 0.001). The H group exhibited significantly more advanced frailty than the N group (p = 0.001). The preoperative JOACMEQ scores for upper extremity, lower extremity, and bladder function were significantly worse in the H group than in the N group (p = 0.020, 0.003, and 0.007, respectively) and remained significant following the multivariable model. Both groups had favorable surgical outcomes, but quality of life improvements were significant in the N group (p = 0.005) but not in the H group (p = 0.900).</p><p><strong>Conclusions: </strong>Older DCM patients with hyperpolypharmacy had more severe preoperative symptoms. Although surgery is a viable treatment option for this population, thorough preoperative informed consent regarding surgical outcomes is critically important.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regional Differences in Characteristics, Service Utilization, and Outcome of Patients Receiving Physician-Led Home Visit Care in Japan: A Nationwide Study.","authors":"Yu Sun, Jun Komiyama, Masao Iwagami, Nobuo Sakata, Satoru Yoshie, Tomoko Ito, Takahiro Sugiyama, Kimikazu Kashiwagi, Nanako Tamiya","doi":"10.1111/ggi.70202","DOIUrl":"https://doi.org/10.1111/ggi.70202","url":null,"abstract":"<p><strong>Aim: </strong>Physician-led home-visit care has become essential in the super-aged society of Japan. To develop region-specific service systems, understanding regional differences in patient profiles is essential. This study aimed to describe regional differences in patient characteristics, service utilization, and outcomes, and to assess the associations between regional healthcare resources and patient outcomes.</p><p><strong>Methods: </strong>This retrospective study used linked data from the National Database of Health Insurance Claims and Specific Health Checkups and the Japanese Long-term Care Database (April 2020-March 2021). Patients aged ≥ 65 years receiving regular physician-led home visits in October 2020 were included. Analyses were conducted by prefecture and region. Associations between regional healthcare resources and patient outcomes were assessed using Spearman's correlation coefficients (ρ).</p><p><strong>Results: </strong>Among 337 863 patients, regional variations were observed. Western Japan had a higher prevalence of cancer, heart disease, respiratory disease, and orthopedic disorders, whereas Tohoku showed the highest rates of high care-need levels and home nursing utilization. Hospitalization risk was highest in western Japan, whereas in-home deaths were more frequent in eastern Japan. Hospital bed density was positively correlated with hospitalization risk (ρ = 0.62) and negatively with 6-month mortality risk (ρ = -0.44). Utilization of enhanced home care support clinics/hospitals was moderately associated with higher in-home death risks (ρ = 0.49).</p><p><strong>Conclusions: </strong>Substantial regional differences exist in patient characteristics, service utilization, and outcomes among older adults receiving physician-led home-visit care. Healthcare resources were strongly associated with hospitalization and end-of-life care, highlighting the need for region-specific strategies to optimize healthcare delivery and resource allocation for the super-aged society of Japan.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145225110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atypical Semantic Variant Primary Progressive Aphasia With Right Temporal Atrophy in an Ambidextrous Older Adult.","authors":"Shinichiro Maeshima, Keita Sakurai, Aiko Osawa, Akinori Takeda, Hidenori Arai","doi":"10.1111/ggi.70196","DOIUrl":"https://doi.org/10.1111/ggi.70196","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145225144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Copper Deficiency Anemia in Older Adults.","authors":"Masato Takasaki, Takuya Omura, Takahiro Kamihara, Taiki Sugimoto, Ken Tanaka, Kenta Motegi, Akira Katsumi, Haruhiko Tokuda","doi":"10.1111/ggi.70201","DOIUrl":"https://doi.org/10.1111/ggi.70201","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145225092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to \"Reconsidering Cost-Effectiveness Claims of Short-Term Prevention Services in Japan\".","authors":"Ryota Watanabe, Masashige Saito, Kazushige Ide, Katsunori Kondo","doi":"10.1111/ggi.70191","DOIUrl":"https://doi.org/10.1111/ggi.70191","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145206421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Serum Creatinine-Cystatin C Ratio With Hospital-Associated Complications and Post-Discharge Mortality.","authors":"Yosuke Yamada, Hirotaka Nakashima, Masaaki Nagae, Kazuhisa Watanabe, Chisato Fujisawa, Hitoshi Komiya, Tomihiko Tajima, Tomomichi Sakai, Shosuke Satake, Hiroyuki Umegaki","doi":"10.1111/ggi.70206","DOIUrl":"https://doi.org/10.1111/ggi.70206","url":null,"abstract":"<p><strong>Aim: </strong>To examine the associations of serum creatinine-cystatin C ratio (CCR) at admission with mortality at 3 months post-discharge and the incidence of hospital-associated complications (HAC).</p><p><strong>Methods: </strong>The study was conducted at 2 centers and included patients admitted to and discharged from geriatric wards between October 2019 and July 2023. Patient backgrounds were compared according to mortality at 3 months post-discharge. Next, logistic regression analysis was performed using mortality at 3 months post-discharge as the objective variable. Similarly, logistic regression analysis was performed with the incidence of HAC as the objective variable.</p><p><strong>Results: </strong>Two hundred thirty-one patients were included in the analysis. The death group had significantly lower CCR (p < 0.001). In logistic regression analysis adjusted for age and sex, a low CCR was associated with increased mortality (odds ratio 3.260, p = 0.003). This association remained significant even after additional adjustment for kidney function (odds ratio 2.710, p = 0.014). The lowest CCR quartile showed a similar trend with an increased risk of death at 3 months compared to the highest quartile, even after extensive adjustment for demographics, kidney function, comorbidities, frailty, and cognitive function (Odds Ratio 4.157, p = 0.086). On the other hand, no significant association was found between CCR and the incidence of HAC.</p><p><strong>Conclusions: </strong>A low CCR predicted higher post-discharge mortality after basic adjustment; although the association attenuated when frailty and cognition were included, a risk increase persisted for the lowest versus highest quartile. Measuring CCR in hospitalized older adults may be useful for early identification of patients at high risk of death.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145199016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Chewing difficulty, swallowing problems, xerostomia and cause-specific mortality among older adults: A 7-year follow-up JAGES cohort study\".","authors":"Pinar Soysal, Irem Tanriverdi","doi":"10.1111/ggi.70181","DOIUrl":"https://doi.org/10.1111/ggi.70181","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145198997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is there a benefit to training older fallers using the backward chaining method to prevent complications of falls?","authors":"Julien Moyet, Frédéric Bloch","doi":"10.1111/ggi.70188","DOIUrl":"https://doi.org/10.1111/ggi.70188","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145199132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical activity associations with physical function and body composition among community-dwelling older adults in Japan: The Kyotango Longevity Cohort Study.","authors":"Motonori Kubo, Norikazu Hishikawa, Hironari Shinjo, Suzuyo Ohashi, Koshiro Sawada, Satoaki Matoba, Yasuo Mikami","doi":"10.1111/ggi.70189","DOIUrl":"https://doi.org/10.1111/ggi.70189","url":null,"abstract":"<p><strong>Aim: </strong>Physical activity benefits health, whereas physical inactivity increases the risk of age-related conditions and adverse health outcomes. Kyotango City in Japan is known for its residents' longevity, and many centenarians live there. This study investigated the physical activity associations with physical function and body composition in older adults living in this area.</p><p><strong>Methods: </strong>Community-dwelling older adults (n = 727; mean age 74.1 years; 59.4% women) participated in this study. Multiple linear regression analyses were carried out to examine objectively-measured physical activity associations with physical function (handgrip strength, knee extension strength and maximum gait speed) and body composition (skeletal muscle mass index and whole-body phase angle), adjusting for potential confounders. Additionally, isotemporal substitution models were applied to estimate changes resulting from replacing sedentary behavior with light-intensity physical activity (LPA) and moderate-to-vigorous-intensity physical activity (MVPA).</p><p><strong>Results: </strong>All physical function and body composition indicators were significantly associated with SB and MVPA (all P < 0.050). However, LPA was associated with only handgrip strength and body composition indicators. Replacing 30 min of SB per day with LPA was associated with a 0.176 kg increase in handgrip strength, 0.018 kg/m² increase in skeletal muscle mass index and 0.016° increase in whole-body phase angle. Alternatively, replacing sedentary behavior with MVPA improved all physical function and body composition indicators.</p><p><strong>Conclusions: </strong>Older adults in a region of Japan known for longevity might maintain physical function and favorable body composition through engaging in abundant physical activity. Public health strategies should prioritize MVPA promotion while recognizing LPA's complementary role for physically inactive older adults. Geriatr Gerontol Int 2025; ••: ••-••.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Poor Appetite Negatively Affects Recovery of Swallowing Function During Post-Acute Rehabilitation.","authors":"Akio Shimizu, Xiaojing Sharon Wu, Shinsuke Nagami, Katsuya Nakamura, Jun Kayashita, Akiko Nomoto, Ichiro Fujishima, Ryo Momosaki","doi":"10.1111/ggi.70198","DOIUrl":"https://doi.org/10.1111/ggi.70198","url":null,"abstract":"<p><strong>Purpose: </strong>Impaired swallowing function is prevalent among older adults, significantly impacting nutritional status and quality of life. Although appetite plays a crucial role in nutrition and clinical recovery, its influence on swallowing function recovery remains unclear. This study aimed to clarify the relationship between poor appetite and swallowing recovery in older adults undergoing rehabilitation.</p><p><strong>Methods: </strong>This retrospective cohort study analyzed data from 309 hospitalized older adults (aged ≥ 65 years) admitted to a post-acute rehabilitation ward with diagnosed impaired swallowing function. Appetite at admission was assessed using the Simplified Nutritional Appetite Questionnaire for Japanese Elderly (SNAQ-JE). Swallowing function was evaluated at discharge using the Food Intake Level Scale (FILS). Multivariable analyses adjusted for age, sex, nutritional status, sarcopenia, cognitive function, functional independence, and clinical characteristics.</p><p><strong>Results: </strong>Among participants (mean age 80.3 ± 7.9 years; 57.6% female), 41.4% had poor appetite. Patients with poor appetite showed significantly lower FILS scores at discharge compared to those with normal appetite (p = 0.002). In adjusted analyses, poor appetite remained negatively associated with FILS scores (Estimate: -0.224, 95% CI: -0.435 to -0.013, p = 0.038). Similarly, poor appetite was associated with impaired swallowing function at discharge (odds ratio: 2.11, 95% confidence interval: 1.16-3.92, p = 0.016).</p><p><strong>Conclusions: </strong>Poor appetite was negatively associated with the recovery of swallowing function among older patients undergoing post-acute rehabilitation. Early evaluation of appetite may assist in identifying barriers to the recovery of swallowing function within this population.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}