Geriatrics & Gerontology International最新文献

{"title":"Chapter 1: Effectiveness of each element of the comprehensive geriatric assessment (CGA): English translation of the Japanese CGA-based healthcare guidelines 2024","authors":"Koji Shibasaki, Sumito Ogawa, Tatsuya Hosoi, Shinya Ishii, Katsuyoshi Mizukami, Hiroyuki Umegaki, Fumihiro Mizokami, Shosuke Satake, Masahiro Akishita","doi":"10.1111/ggi.15086","DOIUrl":"https://doi.org/10.1111/ggi.15086","url":null,"abstract":"<p>Is screening with the comprehensive geriatric assessment (CGA) useful in older adults?</p><p>The following were considered important in developing recommendations for this CQ: reduction in mortality for outpatients, inpatients, and institutionalized patients, reduction in the length of stay, improvement in polypharmacy, and increase in costs.</p><p>Is ADL assessment useful in older adults?</p><p>The following were considered important in developing recommendations for this CQ: reducing mortality for outpatients, inpatients, and institutionalized older adults, increasing institutionalization, increasing costs, and optimizing care services.</p><p>Is it useful to assess the CGA in older adults using cognitive assessment tools?</p><p>The following were considered important in developing recommendations for this CQ: improving the diagnosis rate of dementia, improving the diagnosis rate of mild cognitive impairment, optimizing comorbidity management, and increasing costs.</p><p>Is depression assessment useful in older adults with physical disease? Which depression scales are useful?</p><p>The following were considered important in developing recommendations for this CQ: reduction in mortality and hospital admission/readmission rates that could be identified as outcomes. A study on improving polypharmacy was used as a reference for the recommendations.</p><p>Is it useful to assess motivation in older adults with possible apathy? Which measures of motivation are useful?</p><p>The following were considered important in developing recommendations for this CQ: physical and motor function that could be identified as an outcome.</p><p>Is it advisable to assess the QOL in older adult care?</p><p>Are interventions based on the assessment of social factors useful in older adults?</p><p>The following were considered important in developing recommendations for this CQ: improving QOL, increasing costs, and improving ADLs as a result of interventions based on social factors.</p><p>The following were considered important in developing recommendations for this CQ: optimizing care services, improving ADLs, optimizing management of comorbidities, and increasing costs.</p><p>The following were considered important in developing recommendations for this CQ: optimizing care services, improving ADLs, improving nutritional status, increasing costs, and increased costs were considered important.</p><p>SO received lecture fee from Daiichi Sankyo. SI received funding from Nihon Kijyun Shingu, Sompo Care, and Hoshizaki. KM received lecture fees from Eisai and Tsumura. HU received research funding from Astellas Pharma, Abbott Japan, Chugai Pharmaceutical, Daiichi Sankyo, Eisai, Merck & Co., Fukuda Lifetech, FUJIFILM Toyama Chemical, FUJIFILM RI Pharma, Kracie, Mitsubishi-Tanabe Pharma, Mochida Pharmaceutical, Ono Pharmaceutical, Otsuka Pharmaceutical, Pfizer, Sanofi, Sumitomo Dainippon Pharma, Takeda, and Tsumura. MA received research funding from Astellas Pharma, Bayer Ya","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 S1","pages":"9-15"},"PeriodicalIF":2.4,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ggi.15086","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Durability of antibody titers and associated factors after the booster dose of COVID-19 mRNA vaccination in Japanese SARS-CoV-2 infection-naive residents in geriatric intermediate care facilities.","authors":"Ayane Kasamatsu, Satoko Ohfuji, Asae Suita, Kyoko Kondo, Hiroyuki Nakata, Tetsuya Kita, Akifumi Deguchi, Mikio Fujimoto, Kazuko Iba, Hideki Sakamoto, Kaori Iwasaka, Noboru Sakamoto, Hikaru Sakamoto, Yoshiko Yodoi, Yasutoshi Kido, Yu Nakagama, Ayako Konishi, Emiko Mukai, Kazuhiro Matsumoto, Tomoka Matsuura, Tetsuo Kase, Hiroshi Kakeya, Wakaba Fukushima, Yoshio Hirota","doi":"10.1111/ggi.70028","DOIUrl":"https://doi.org/10.1111/ggi.70028","url":null,"abstract":"<p><strong>Aim: </strong>Elderly adults are at higher risk for severe COVID-19 infection. This multicenter, prospective cohort study assessed immunogenicity after COVID-19 vaccinations in elderly residents compared with staff in geriatric intermediate care facilities. Predictors of lower antibody titers were also examined.</p><p><strong>Methods: </strong>Fifty-four residents and 117 staff who had received three doses of the COVID-19 mRNA vaccine between March 2021 and September 2022 were included. Anti-receptor binding domain antibody titers were measured 3-4 weeks and 6 months after the vaccinations. Adjusted geometric mean titers (GMT) were calculated using multivariable linear mixed effects models.</p><p><strong>Results: </strong>After the first dose, residents had a significantly lower adjusted GMT than did staff (115 vs. 267 AU/mL, P < 0.01), whereas the adjusted GMT of residents was comparable to that of staff after the third dose (14 178 vs. 12 159 AU/mL, P = 0.63). However, 6 months later, the adjusted GMT of residents was less than half that of staff (1645 vs. 4302 AU/mL, P < 0.01). In residents, steroid users had a significantly lower adjusted GMT than did steroid nonusers.</p><p><strong>Conclusions: </strong>The third dose of mRNA vaccine boosted the immune response of elderly residents. However, their antibody titers, particularly in steroid users, were highly attenuated 6 months after the last vaccination. For this population, attention should be focused on additional vaccinations. Geriatr Gerontol Int 2025; ••: ••-••.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of participating in Kayoi-no-ba during the COVID-19 pandemic on frailty 1 year later in older adults.","authors":"Hiroki Mori, Satoshi Seino, Yuri Yokoyama, Mari Yamashita, Yu Nofuji, Takuya Ueda, Akihiko Kitamura, Shinji Hattori, Minoru Yamada, Katsunori Kondo, Hidenori Arai, Hayato Uchida, Erika Kobayashi, Yoshinori Fujiwara","doi":"10.1111/ggi.70029","DOIUrl":"https://doi.org/10.1111/ggi.70029","url":null,"abstract":"<p><strong>Aim: </strong>This study examined the short-term effects of participation in Kayoi-no-ba - community gathering places for residents to contribute to care prevention with the support of volunteers in Japan - on frailty status during the coronavirus disease 2019 (COVID-19) pandemic, based on a 1-year longitudinal study of older adults.</p><p><strong>Methods: </strong>Participants (n = 3899) were aged ≥65 years. At baseline, they were classified into four groups, based on their frequency of participation in Kayoi-no-ba before and after the COVID-19 pandemic: the nonparticipation group, the continued participation group, the interrupted participation group and the new participation group. Frailty status, assessed using the modified Kihon Checklist, was the dependent variable. A generalized linear mixed-effects model was used to compare frailty status changes after a 1-year follow up in the four groups.</p><p><strong>Results: </strong>The frailty prevalence at baseline was 30.8% in the nonparticipation group, and 37.2% in the participation group. The frailty prevalence in the participation group was significantly reduced at the 1-year follow up (-3.9 percentage points [95% CI -7.4, -0.5]), compared with that of the nonparticipation group. In subgroup analyses, the frailty prevalence was reduced at the 1-year follow up in the order of continued participation group (-4.5 percentage points [95% CI -8.9, -0.2]), new participation group (-4.0 percentage points [95% CI -12.9, 5.0]), and interrupted participation group (-2.4 percentage points [95% CI -9.1, 4.3]), compared with the nonparticipation group (P = 0.024 for trend).</p><p><strong>Conclusions: </strong>Even during the COVID-19 pandemic, participation in Kayoi-no-ba was effective in preventing/reducing frailty. Thus, avoiding prolonged nonparticipation in Kayoi-no-ba might be important. Geriatr Gerontol Int 2025; ••: ••-••.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between education for home care nurses and their practice of comprehensive client assessment: A cross-sectional study.","authors":"Ryousuke Yamada, Ayumi Igarashi, Kosuke Kashiwabara, Chie Fukui, Masumi Shinohara, Maiko Noguchi-Watanabe, Sakiko Fukui, Noriko Yamamoto-Mitani","doi":"10.1111/ggi.70024","DOIUrl":"https://doi.org/10.1111/ggi.70024","url":null,"abstract":"<p><strong>Aim: </strong>This study examined the home care nurses' implementation of comprehensive assessment of their clients, their education and the association betwwen the two. Staff education in home care nursing agencies has the potential to improve nurses' comprehensive client assessment, contributing to the provision of high-quality home care nursing services.</p><p><strong>Methods: </strong>A cross-sectional questionnaire survey was conducted to investigate educational approaches provided by agencies and comprehensive assessment by home care nurses. Multilevel regression analyses were performed to examine the association between education and comprehensive assessment.</p><p><strong>Results: </strong>We analyzed data from 105 clients, based on 78 nurses' assessments, across 11 agencies with respect to their respective staff education systems. Various educational programs for novices and all staff were provided. In the multilevel regression analysis, having a designated individual in charge of staff education and regular case reviews for all staff were significantly associated with more comprehensive assessments.</p><p><strong>Conclusions: </strong>Ensuring specific educational opportunities for all home care nurses, rather than solely for novices, might improve their comprehensive assessment in home care nursing agencies. Designating educators and introducing regular case reviews as part of agencies' educational systems may improve comprehensive assessment. Geriatr Gerontol Int 2025; ••: ••-••.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early retirement as a multidimensional construct: Resolving contradictions in health outcome research.","authors":"Enzo Emanuele, Piercarlo Minoretti","doi":"10.1111/ggi.70030","DOIUrl":"https://doi.org/10.1111/ggi.70030","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reversed loneliness development after age 65 for men and women: Modeling of the age trajectories of loneliness using national cohorts in Taiwan and Japan.","authors":"Ching-Ju Chiu, Szu-Yu Hou, Erika Kobayashi, Yu-Cheng Lin, Yun-An Chen, Hiroshi Murayama, Shohei Okamoto, Yi-Hsuan Chen, Yi-Jia Huang","doi":"10.1111/ggi.70022","DOIUrl":"https://doi.org/10.1111/ggi.70022","url":null,"abstract":"<p><strong>Aim: </strong>This study depicts the age trajectories of loneliness and gender differences among older adults in Taiwan and Japan.</p><p><strong>Methods: </strong>Two nationally representative data sets for older adults in Taiwan and Japan were obtained from the Taiwan Longitudinal Study on Aging (TLSA, 1996-2011) and the National Survey of the Japanese Elderly (NSJE, 1996-2012), respectively. The analytic sample included 3037 and 1974 older adults aged 65 and over at baseline in Taiwan and Japan, respectively.</p><p><strong>Results: </strong>The prevalence rate of loneliness for adults aged 65+ living in the community was 23.64% in Taiwan and 17.03% in Japan. Higher average levels (β_Taiwan = 0.1508, P < 0.001) and rates of increment (β_Taiwan*age = 0.0068, P < 0.05) in loneliness development were found in Taiwan as compared with Japan. In addition, although women reported higher levels of loneliness compared with men at age 65 (29.0% vs. 19.4% in Taiwan, and 19.3% vs. 13.9% in Japan), a soaring development of loneliness with accelerated rates of increment after age 65 was observed in men in both countries.</p><p><strong>Conclusions: </strong>Lonliness in old age is very different between men and women. Women's loneliness curve shows an inverted U state: Although they feel more lonely than men during midlife, it has a downward trend as they get older. On the contrary, men's loneliness curve shows an upward U-shaped curve: After retirement, both Japanese and Taiwanese men continue to rise. Geriatr Gerontol Int 2025; ••: ••-••.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel predictors of infection-related rehospitalization in older patients with heart failure in Japan.","authors":"Kei Kawada, Tomoaki Ishida, Toru Kubo, Tomoyuki Hamada, Hitoshi Fukuda, Yuki Hyohdoh, Kazuya Kawai, Yoko Nakaoka, Toshikazu Yabe, Takashi Furuno, Eisuke Yamada, Shinji Abe, Kohei Jobu, Mitsuhiro Goda, Yukihiro Hamada, Hiroaki Kitaoka, Keisuke Ishizawa","doi":"10.1111/ggi.70019","DOIUrl":"https://doi.org/10.1111/ggi.70019","url":null,"abstract":"<p><strong>Aim: </strong>Rehospitalization of patients with heart failure (HF) incurs high health care costs and increased mortality. Infection-related rehospitalizations in patients with HF occur frequently, and the risk increases with age. This study aimed to identify the factors associated with infection-related rehospitalizations in older patients with HF.</p><p><strong>Methods: </strong>Demographic, clinical, and pharmacological data from 1061 patients with acute HF who were enrolled in the Kochi Registry of Subjects With Acute Decompensated Heart Failure (Kochi YOSACOI study) were analyzed. Additionally, a machine learning approach was applied in addition to the traditional statistical analysis model. Of the patients hospitalized for HF, 729 were ultimately analyzed.</p><p><strong>Results: </strong>During the 2-year postdischarge follow-up period, 121 (17%) patients were readmitted for infections. Logistic regression analysis identified a Japanese Cardiovascular Health Study (J-CHS) score of ≥3 (odds ratio, 1.83 [95% confidence interval, 1.18-2.83]; P = 0.007) at discharge as a key factor for infection-related rehospitalizations. Machine learning models confirmed that a higher J-CHS score and lower estimated glomerular filtration rate (eGFR) increased the risk of infection-related rehospitalizations. Decision tree analysis classified the risk into high (J-CHS score ≥3), medium (J-CHS score <3; eGFR ≤35.0) and low (J-CHS score <3; eGFR >35.0) groups.</p><p><strong>Conclusions: </strong>Infection-related rehospitalizations occur in older patients with HF and are associated with frailty and eGFR. These findings provide valuable insights for health care providers to better manage the risk of infection-related rehospitalizations in older patients with HF, potentially improving patient outcomes. Geriatr Gerontol Int 2025; ••: ••-••.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differential associations between physical frailty and aspects of well-being in community-dwelling older adults.","authors":"Yukiko Nishita, Sayaka Kubota, Mana Tateishi, Chikako Tange, Rei Otsuka","doi":"10.1111/ggi.70027","DOIUrl":"https://doi.org/10.1111/ggi.70027","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemoglobin to red cell distribution width ratio predicts postoperative delirium in older patients undergoing hip fracture surgery: A retrospective cohort study.","authors":"Xinyu Cao, Huanhuan Zhang, Yi Li, Meinv Liu, Jinhua He, Jianli Li","doi":"10.1111/ggi.70023","DOIUrl":"https://doi.org/10.1111/ggi.70023","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to investigate the predictive effect of hemoglobin to red cell distribution width ratio (HRR) on postoperative delirium (POD) in older patients undergoing hip fracture surgery.</p><p><strong>Methods: </strong>POD was diagnosed by capturing descriptive words from the medical records. The correlation between POD and HRR was determined using logistic regression analysis, and the receiver operating characteristic curve was used to further evaluate the value of HRR in predicting POD.</p><p><strong>Results: </strong>In total, 202 older patients accepting hip fracture surgery were included in our study. The result of multiple logistic regression analysis presented HRR (odds ratio, 0.504 [95% confidence interval, 0.340-0.747]; P < 0.001), American Society of Anesthesiologists physical status >2, and neutrophils were independently correlated with POD. The area under the curve of HRR was 0.746 (95% confidence interval, 0.676-0.815), and the optimal cutoff value was 8.322.</p><p><strong>Conclusions: </strong>HRR, American Society of Anesthesiologists physical status >2 and neutrophils could independently predict POD in older patients undergoing hip fracture surgery, and HRR had satisfactory predictive value. However, further research is needed to confirm our findings. Geriatr Gerontol Int 2025; ••: ••-••.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143566741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anticholinergic burden quantified using the Japanese risk scale as a predictor of frailty and sarcopenia among community-dwelling older adults: A 9-year Kashiwa cohort study.","authors":"Tomoki Tanaka, Masahiro Akishita, Taro Kojima, Bo-Kyung Son, Katsuya Iijima","doi":"10.1111/ggi.70012","DOIUrl":"https://doi.org/10.1111/ggi.70012","url":null,"abstract":"<p><strong>Aim: </strong>Given the adverse effects of anticholinergic drugs and the necessity for medication evaluation tools in the aging population, a comprehensive scale to assess the total anticholinergic burden in Japan was developed. We examined the longitudinal association between the anticholinergic burden, quantified using the Japanese Anticholinergic Drug Risk Scale, and the development of frailty and sarcopenia in older adults.</p><p><strong>Methods: </strong>In this longitudinal population-based cohort study, 2044 older residents without long-term care needs were randomly selected from a community in Kashiwa, Japan. Baseline data were collected in 2012, with follow-ups in 2013, 2014, 2016, 2018, and 2021. Medications were identified through interviews and assessed with the Screening Tool for Older Persons' Appropriate Prescriptions for the Japanese. The anticholinergic burden was quantified using the Japanese Anticholinergic Risk Scale. We evaluated new-onset frailty and sarcopenia using the Cardiovascular Health Study Index and Asian Working Group for Sarcopenia 2019 criteria, respectively.</p><p><strong>Results: </strong>Of the 1549 participants without sarcopenia or frailty at baseline (age 72.5 ± 5.5 years; 49.1% women; median follow-up 6.0 years), 274 and 230 developed new-onset frailty and sarcopenia, respectively, during follow-up. After adjusting for potential confounders, an anticholinergic burden score ≥3 was strongly associated with new-onset frailty and sarcopenia (adjusted hazard ratio [95% confidence interval]: 2.45 [1.52-3.94] and 2.01 [1.20-3.35], respectively).</p><p><strong>Conclusions: </strong>Anticholinergic burden is a predictor of frailty and sarcopenia in community-dwelling older adults. Effective evaluation and management of anticholinergic burden using the Japanese Anticholinergic Drug Risk Scale are crucial for promoting healthy aging and mitigating adverse health outcomes. Geriatr Gerontol Int 2025; ••: ••-••.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143566727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}