Geriatrics & Gerontology International最新文献

{"title":"Copper Deficiency Anemia in Older Adults.","authors":"Masato Takasaki, Takuya Omura, Takahiro Kamihara, Taiki Sugimoto, Ken Tanaka, Kenta Motegi, Akira Katsumi, Haruhiko Tokuda","doi":"10.1111/ggi.70201","DOIUrl":"https://doi.org/10.1111/ggi.70201","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145225092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to \"Reconsidering Cost-Effectiveness Claims of Short-Term Prevention Services in Japan\".","authors":"Ryota Watanabe, Masashige Saito, Kazushige Ide, Katsunori Kondo","doi":"10.1111/ggi.70191","DOIUrl":"https://doi.org/10.1111/ggi.70191","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145206421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Serum Creatinine-Cystatin C Ratio With Hospital-Associated Complications and Post-Discharge Mortality.","authors":"Yosuke Yamada, Hirotaka Nakashima, Masaaki Nagae, Kazuhisa Watanabe, Chisato Fujisawa, Hitoshi Komiya, Tomihiko Tajima, Tomomichi Sakai, Shosuke Satake, Hiroyuki Umegaki","doi":"10.1111/ggi.70206","DOIUrl":"https://doi.org/10.1111/ggi.70206","url":null,"abstract":"<p><strong>Aim: </strong>To examine the associations of serum creatinine-cystatin C ratio (CCR) at admission with mortality at 3 months post-discharge and the incidence of hospital-associated complications (HAC).</p><p><strong>Methods: </strong>The study was conducted at 2 centers and included patients admitted to and discharged from geriatric wards between October 2019 and July 2023. Patient backgrounds were compared according to mortality at 3 months post-discharge. Next, logistic regression analysis was performed using mortality at 3 months post-discharge as the objective variable. Similarly, logistic regression analysis was performed with the incidence of HAC as the objective variable.</p><p><strong>Results: </strong>Two hundred thirty-one patients were included in the analysis. The death group had significantly lower CCR (p < 0.001). In logistic regression analysis adjusted for age and sex, a low CCR was associated with increased mortality (odds ratio 3.260, p = 0.003). This association remained significant even after additional adjustment for kidney function (odds ratio 2.710, p = 0.014). The lowest CCR quartile showed a similar trend with an increased risk of death at 3 months compared to the highest quartile, even after extensive adjustment for demographics, kidney function, comorbidities, frailty, and cognitive function (Odds Ratio 4.157, p = 0.086). On the other hand, no significant association was found between CCR and the incidence of HAC.</p><p><strong>Conclusions: </strong>A low CCR predicted higher post-discharge mortality after basic adjustment; although the association attenuated when frailty and cognition were included, a risk increase persisted for the lowest versus highest quartile. Measuring CCR in hospitalized older adults may be useful for early identification of patients at high risk of death.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145199016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Chewing difficulty, swallowing problems, xerostomia and cause-specific mortality among older adults: A 7-year follow-up JAGES cohort study\".","authors":"Pinar Soysal, Irem Tanriverdi","doi":"10.1111/ggi.70181","DOIUrl":"https://doi.org/10.1111/ggi.70181","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145198997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is there a benefit to training older fallers using the backward chaining method to prevent complications of falls?","authors":"Julien Moyet, Frédéric Bloch","doi":"10.1111/ggi.70188","DOIUrl":"https://doi.org/10.1111/ggi.70188","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145199132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical activity associations with physical function and body composition among community-dwelling older adults in Japan: The Kyotango Longevity Cohort Study.","authors":"Motonori Kubo, Norikazu Hishikawa, Hironari Shinjo, Suzuyo Ohashi, Koshiro Sawada, Satoaki Matoba, Yasuo Mikami","doi":"10.1111/ggi.70189","DOIUrl":"https://doi.org/10.1111/ggi.70189","url":null,"abstract":"<p><strong>Aim: </strong>Physical activity benefits health, whereas physical inactivity increases the risk of age-related conditions and adverse health outcomes. Kyotango City in Japan is known for its residents' longevity, and many centenarians live there. This study investigated the physical activity associations with physical function and body composition in older adults living in this area.</p><p><strong>Methods: </strong>Community-dwelling older adults (n = 727; mean age 74.1 years; 59.4% women) participated in this study. Multiple linear regression analyses were carried out to examine objectively-measured physical activity associations with physical function (handgrip strength, knee extension strength and maximum gait speed) and body composition (skeletal muscle mass index and whole-body phase angle), adjusting for potential confounders. Additionally, isotemporal substitution models were applied to estimate changes resulting from replacing sedentary behavior with light-intensity physical activity (LPA) and moderate-to-vigorous-intensity physical activity (MVPA).</p><p><strong>Results: </strong>All physical function and body composition indicators were significantly associated with SB and MVPA (all P < 0.050). However, LPA was associated with only handgrip strength and body composition indicators. Replacing 30 min of SB per day with LPA was associated with a 0.176 kg increase in handgrip strength, 0.018 kg/m² increase in skeletal muscle mass index and 0.016° increase in whole-body phase angle. Alternatively, replacing sedentary behavior with MVPA improved all physical function and body composition indicators.</p><p><strong>Conclusions: </strong>Older adults in a region of Japan known for longevity might maintain physical function and favorable body composition through engaging in abundant physical activity. Public health strategies should prioritize MVPA promotion while recognizing LPA's complementary role for physically inactive older adults. Geriatr Gerontol Int 2025; ••: ••-••.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Poor Appetite Negatively Affects Recovery of Swallowing Function During Post-Acute Rehabilitation.","authors":"Akio Shimizu, Xiaojing Sharon Wu, Shinsuke Nagami, Katsuya Nakamura, Jun Kayashita, Akiko Nomoto, Ichiro Fujishima, Ryo Momosaki","doi":"10.1111/ggi.70198","DOIUrl":"https://doi.org/10.1111/ggi.70198","url":null,"abstract":"<p><strong>Purpose: </strong>Impaired swallowing function is prevalent among older adults, significantly impacting nutritional status and quality of life. Although appetite plays a crucial role in nutrition and clinical recovery, its influence on swallowing function recovery remains unclear. This study aimed to clarify the relationship between poor appetite and swallowing recovery in older adults undergoing rehabilitation.</p><p><strong>Methods: </strong>This retrospective cohort study analyzed data from 309 hospitalized older adults (aged ≥ 65 years) admitted to a post-acute rehabilitation ward with diagnosed impaired swallowing function. Appetite at admission was assessed using the Simplified Nutritional Appetite Questionnaire for Japanese Elderly (SNAQ-JE). Swallowing function was evaluated at discharge using the Food Intake Level Scale (FILS). Multivariable analyses adjusted for age, sex, nutritional status, sarcopenia, cognitive function, functional independence, and clinical characteristics.</p><p><strong>Results: </strong>Among participants (mean age 80.3 ± 7.9 years; 57.6% female), 41.4% had poor appetite. Patients with poor appetite showed significantly lower FILS scores at discharge compared to those with normal appetite (p = 0.002). In adjusted analyses, poor appetite remained negatively associated with FILS scores (Estimate: -0.224, 95% CI: -0.435 to -0.013, p = 0.038). Similarly, poor appetite was associated with impaired swallowing function at discharge (odds ratio: 2.11, 95% confidence interval: 1.16-3.92, p = 0.016).</p><p><strong>Conclusions: </strong>Poor appetite was negatively associated with the recovery of swallowing function among older patients undergoing post-acute rehabilitation. Early evaluation of appetite may assist in identifying barriers to the recovery of swallowing function within this population.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research Progress on the Prognostic Significance of Systemic Immune Inflammation Index in Patients With Resected Colorectal Cancer: A Meta-Analysis.","authors":"Wenqing Chen, Xiangrui Li, Jiayue Xia, Da Pan, Xiaotian Chen, Guiju Sun","doi":"10.1111/ggi.70197","DOIUrl":"https://doi.org/10.1111/ggi.70197","url":null,"abstract":"<p><strong>Aim: </strong>The systemic immune-inflammation index (SII) serves as a prognostic index of survival among cancer patients. SII is calculated based on the counts of lymphocytes, neutrophils, and platelets. This study aimed to conduct a meta-analysis to explore the predictive role of SII in patients who have undergone surgery for colorectal cancer (CRC).</p><p><strong>Methods: </strong>A comprehensive search of Web of Science, PubMed, the Cochrane Library, and EMBASE databases was performed to include studies published until 12 Dec 2023. The association between SII and overall survival (OS) in CRC patients who had undergone surgery was assessed by hazard ratios (HRs) and 95% confidence intervals (CIs).</p><p><strong>Results: </strong>A total of 10 studies with 4537 cases published between 2017 and 2023 were included in this meta-analysis. The mean age of the patients was 60.8 years. The pooled result showed that high SII was correlated with poorer OS (HR = 2.21, 95% CI = 1.95-2.49, p < 0.001) and poorer DFS (HR = 2.81, 95% CI = 2.36-3.34, p < 0.001) in CRC patients who underwent surgery. The cut-off value of SII to predict OS would be 550. Subgroup analysis of SII and survival outcomes in CRC confirmed these findings.</p><p><strong>Conclusions: </strong>SII emerges as a useful tool for prediction of survival outcomes in patients undergoing CRC surgery, especially in the elderly population over 60 years old.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145185426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frailty, Time-Windowed Mortality, and the Neglected Burden in Younger Adults.","authors":"Yalcin Golcuk","doi":"10.1111/ggi.70192","DOIUrl":"https://doi.org/10.1111/ggi.70192","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145185450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Constipation, frailty, and cardiovascular mortality in acute decompensated heart failure: Methodological considerations for the CFA-AHEAD risk model.","authors":"Xinxin Liu, Hao Liu","doi":"10.1111/ggi.70180","DOIUrl":"https://doi.org/10.1111/ggi.70180","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145174649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}