{"title":"Predictive ability of Mini-Cog for postoperative delirium: A systematic review and meta-analysis.","authors":"Shugo Yajima, Kohei Hirose, Hitoshi Masuda","doi":"10.1111/ggi.70067","DOIUrl":"https://doi.org/10.1111/ggi.70067","url":null,"abstract":"<p><strong>Aim: </strong>This study aims to determine the predictive value of the preoperative Mini-Cognitive Assessment Instrument (Mini-Cog) for postoperative delirium (POD), a significant complication in older surgical patients. Given its widespread recommendation despite unclear predictive utility, we will conduct the first meta-analysis to synthesize the available evidence.</p><p><strong>Methods: </strong>A systematic review and meta-analysis were conducted following PRISMA guidelines. Electronic databases (Medline, CINAHL, Cochrane Library, and Web of Science) were searched from inception to May 2024. Studies evaluating the association between preoperative Mini-Cog scores and POD were included. Two independent reviewers performed study selection and data extraction. The methodological quality was assessed using the Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) tool. Random-effects models were used to calculate pooled odds ratios (ORs), sensitivity, and specificity. Sensitivity analyses were performed based on standardized cutoff values and POD assessment methods.</p><p><strong>Results: </strong>Sixteen studies involving 4980 patients were included. Participants' mean/median ages ranged from 70 to 80 years, and the percentage of patients scoring below the Mini-Cog cutoff varied from 12.5% to 60.5%. Low Mini-Cog scores were significantly associated with increased POD risk (OR = 3.79; 95% confidence interval [CI] = 2.81-5.12; I<sup>2</sup> = 57%). The Mini-Cog demonstrated a pooled specificity of 0.80 and sensitivity of 0.50 for POD prediction. Sensitivity analysis of studies using standardized cutoffs (<3) and validated POD assessment tools yielded an OR of 3.40 (95% CI = 2.56-4.53). Half of the included studies showed a low risk of bias across all QUADAS-2 domains. Publication bias assessment using funnel plots and Egger's test showed no significant bias.</p><p><strong>Conclusions: </strong>The Mini-Cog shows moderate predictive ability for POD, with high specificity but limited sensitivity. While it may be valuable as part of comprehensive preoperative assessment, its moderate sensitivity suggests it should not be used as the sole predictor. The variability in surgical populations and assessment methods highlights the need for standardization. Future research should focus on establishing consistent methodologies and exploring the Mini-Cog's efficacy in specific surgical populations to enhance its clinical utility in POD risk stratification. Geriatr Gerontol Int 2025; ••: ••-••.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144005531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Individual factors associated with out-of-hours outpatient visits for emergency medical care and readmissions within 90 days of discharge among older adults: A retrospective cohort study.","authors":"Rumiko Tsuchiya-Ito, Seigo Mitsutake, Chie Teramoto, Shota Hamada, Satoru Yoshie, Nanako Tamiya, Katsuya Iijima, Tatsuro Ishizaki","doi":"10.1111/ggi.70051","DOIUrl":"https://doi.org/10.1111/ggi.70051","url":null,"abstract":"<p><strong>Aim: </strong>Transitional care interventions might help reduce the risk of emergency medical care and readmission after hospital discharge. However, it is unclear whether individual factors differentially affect the risks of these outcomes in Japan. We examined the individual factors associated with out-of-hours outpatient visits and readmissions among older Japanese adults.</p><p><strong>Methods: </strong>This retrospective cohort study analyzed residents of Kashiwa City who were discharged from hospital between 2012 and 2014. The outcomes were out-of-hours outpatient visits and readmissions within 90 days of discharge. The exposures were individual factors, such as age, sex, household income, certified care needs levels, diseases and health services before discharge. Fine-Gray proportional subdistribution hazards models were used to estimate the associations between the individual factors and outcomes.</p><p><strong>Results: </strong>Among 7842 patients, out-of-hours outpatient visits and readmissions occurred in 8.8% and 19.0% of patients, respectively. Patients with ischemic heart disease (subdistribution hazard ratio [SHR] 1.26, 95% confidence interval [CI] 1.06-1.48), dementia (SHR 1.29, 95% CI 1.04-1.61) and hearing impairment (SHR 1.49, 95% CI 1.07-2.07) were more likely to attend out-of-hours outpatient visits. In contrast, patients with other cardiac diseases (SHR 1.17, 95% CI 1.01-1.36), cancer (SHR 1.98, 95% CI 1.65-2.38), chronic obstructive pulmonary disease (SHR 1.26, 95% CI 1.04-1.52) and other lower respiratory tract diseases (SHR 1.16, 95% CI 1.04-1.31) were more likely to be readmitted. The use of discharge planning services was negatively associated with readmissions.</p><p><strong>Conclusion: </strong>Underlying factors for out-of-hours outpatient visits for emergency medical care and readmissions differed. The use of new follow-up methods and other targeted strategies are required in transitional care programs to address disease-specific needs. Geriatr Gerontol Int 2025; ••: ••-••.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143999333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Qiang Zhou, Yuxiu Miao, Fenghua Li, Jianhua Liu, Jianing Li, Na Li
{"title":"Authors' reply for comments on \"Association between base excess and mortality in septic older adults\".","authors":"Qiang Zhou, Yuxiu Miao, Fenghua Li, Jianhua Liu, Jianing Li, Na Li","doi":"10.1111/ggi.70058","DOIUrl":"https://doi.org/10.1111/ggi.70058","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143977553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Şimşek Çelik, Onur Türkdoğan, Tayfun Erdoğan, Pelin Çelik
{"title":"Reply to: Comments on \"PRISMA-7 is a predictor of intensive care unit admission and mortality in older patients in an emergency department\".","authors":"Şimşek Çelik, Onur Türkdoğan, Tayfun Erdoğan, Pelin Çelik","doi":"10.1111/ggi.70056","DOIUrl":"https://doi.org/10.1111/ggi.70056","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143995432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sarcopenia in heart failure: Comparison of prognostic value between the Asian working Group for Sarcopenia 2014 and 2019 criteria.","authors":"Kazuya Saito, Taisuke Nakade, Nobuyuki Kagiyama, Daichi Maeda, Yudai Fujimoto, Tsutomu Sunayama, Taishi Dotare, Kentaro Jujo, Kentaro Kamiya, Hiroshi Saito, Yuki Ogasahara, Emi Maekawa, Masaaki Konishi, Takeshi Kitai, Kentaro Iwata, Hiroshi Wada, Takatoshi Kasai, Hirofumi Nagamatsu, Shin-Ichi Momomura, Yuya Matsue","doi":"10.1111/ggi.70040","DOIUrl":"https://doi.org/10.1111/ggi.70040","url":null,"abstract":"<p><strong>Aim: </strong>Sarcopenia is a prevalent comorbidity among older patients with heart failure. This study aimed to evaluate the differences between sarcopenia diagnosed using the Asian Working Group for Sarcopenia (AWGS) 2014 and 2019 criteria in older patients with heart failure.</p><p><strong>Methods: </strong>This study is a post hoc sub-analysis of data from the FRAGILE-HF study, a prospective, multicenter, observational study. The study included 879 patients aged >65 years who were hospitalized for heart failure decompensation and could walk at discharge. Sarcopenia was diagnosed using criteria from the AWGS 2014 (2014 model) and 2019 (2019 model). The primary outcome was 2-year mortality.</p><p><strong>Results: </strong>Sarcopenia was identified in 186 (21.1%) patients using the 2014 model and 211 (24.0%) patients using the 2019 model. Over the 2-year follow-up period, 158 (18.0%) deaths occurred. Adjusted Cox proportional hazard analysis showed that sarcopenia was significantly associated with 2-year mortality in the 2014 model, whereas only severe sarcopenia was associated with mortality in the 2019 model. Both models showed significant net reclassification improvement when sarcopenia was added to the baseline model (2014 model: 0.358, 2019 model: 0.357). However, no significant difference in net reclassification improvement was observed upon direct comparison between the two models (-0.082, P = 0.376), suggesting comparable performance.</p><p><strong>Conclusions: </strong>The 2014 model shows strong prognostic value for predicting 2-year mortality in patients with heart failure. Although the 2019 model shows similar prognostic value, particularly for severe sarcopenia, it does not significantly outperform the 2014 model. Geriatr Gerontol Int 2025; ••: ••-••.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brijesh Sathian, Hanadi Al Hamad, Ashfaq Ahmad, Javed Iqbal
{"title":"Comment on: \"Relationship between the quality of formal care and family caregivers' positive and negative aspects of caregiving for older patients with chronic conditions\".","authors":"Brijesh Sathian, Hanadi Al Hamad, Ashfaq Ahmad, Javed Iqbal","doi":"10.1111/ggi.70064","DOIUrl":"https://doi.org/10.1111/ggi.70064","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Omar Mohamed Al-Qahtani, Mohammad Ayaz Khan, Brijesh Sathian, Javed Iqbal
{"title":"Role of education in enhancing home care nurses' assessment skills: A closer look at key findings.","authors":"Omar Mohamed Al-Qahtani, Mohammad Ayaz Khan, Brijesh Sathian, Javed Iqbal","doi":"10.1111/ggi.70053","DOIUrl":"https://doi.org/10.1111/ggi.70053","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143997566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Commentary on: \"Dual-task gait test provides limited additional value for fall prediction in care-requiring older adults: A prospective study\".","authors":"Venkata Dileep Kumar Veldi, Rachana Mehta, Ranjana Sah","doi":"10.1111/ggi.70054","DOIUrl":"https://doi.org/10.1111/ggi.70054","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143995331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on: \"Effect of pet therapy on sleep and life quality of elderly individuals\".","authors":"Xiaolin Wang, Qian Zhang","doi":"10.1111/ggi.70057","DOIUrl":"https://doi.org/10.1111/ggi.70057","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143988082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mathias Lundström, Niko Wasenius, Mia Eriksson, Tuija M Mikkola, Eero Kajantie, Johan G Eriksson
{"title":"Leisure-time physical activity predicts levels of advanced glycation end-products in older women: A 15-year follow up from the Helsinki Birth Cohort Study.","authors":"Mathias Lundström, Niko Wasenius, Mia Eriksson, Tuija M Mikkola, Eero Kajantie, Johan G Eriksson","doi":"10.1111/ggi.70049","DOIUrl":"https://doi.org/10.1111/ggi.70049","url":null,"abstract":"<p><strong>Aim: </strong>Physical activity might be able to delay the aging process by reducing levels of advanced glycation end-products (AGEs). However, the influence of physical activity on levels of AGEs remains unclear. We investigated the associations between leisure time physical activity (LTPA) in late midlife and change in LTPA during a 15-year follow up on the levels of AGEs in old age.</p><p><strong>Methods: </strong>We analyzed 767 participants from the Helsinki Birth Cohort Study. LTPA was measured with a validated questionnaire in late midlife and in old age. The levels of AGEs were measured by skin autofluorescence in old age. General linear models and restricted cubic regression spline models were used to study the associations between LTPA and AGEs. Analyses were adjusted for age, alcohol consumption, dietary index, smoking, follow-up time, body mass index and socioeconomic status.</p><p><strong>Results: </strong>Mean levels of AGEs in women (2.33 AU, SD 0.46) were lower than in men (2.49 AU, SD 0.50, P < 0.001). Women in the lowest LTPA quartile had 0.19 AU (95% CI 0.07-0.32, P = 0.002), 0.21 AU (95% CI 0.09-0.33, P = 0.001) and 0.18 AU (95% CI 0.05-0.31, P = 0.006) higher levels of AGEs compared with women in the second, third and fourth quartile. In the restricted cubic regression spline model, levels of AGEs (P = 0.006) were decreasing with increasing LTPA from 0 to 32 METh/week, after which the association plateaued. No associations were found in men.</p><p><strong>Conclusions: </strong>Greater volume of LTPA in late midlife is associated with lower levels of AGEs in skin tissue in old age in women. Geriatr Gerontol Int 2025; ••: ••-••.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144007280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}