Gels最新文献

{"title":"Graphene Oxide-Regulated Calcium Alginate Molecularly Imprinted Hydrogel Films with Enhanced Physico-Mechanical Properties and Selective Protein Recognition.","authors":"Siyu Wang, Haojie Li, Ying Zhang, Zhengchun Yang, Kongyin Zhao","doi":"10.3390/gels12100913","DOIUrl":"https://doi.org/10.3390/gels12100913","url":null,"abstract":"<p><p>Calcium alginate (CaAlg) hydrogels are attractive matrices for molecular imprinting because of their biocompatibility and functionalizability, but their limited mechanical stability and excessive swelling can compromise the integrity and accessibility of molecular recognition sites. In this study, graphene oxide (GO) was incorporated into CaAlg to regulate the physicochemical properties of the hydrogel and construct a bovine serum albumin (BSA)-imprinted hydrogel interface for selective protein recognition and electrochemical sensing. The incorporation of GO effectively reduced swelling and enhanced the mechanical stability of the hydrogel, with the 1 wt.% GO-containing film exhibiting a tensile strength of 1921.15 kPa and the highest fracture energy. The resulting molecularly imprinted hydrogel showed a BSA adsorption capacity of 55.21 mg g^-1 and an imprinting efficiency of 3.68, while preferential recognition of BSA over other proteins was observed. After integration with a carbon electrode, template removal and BSA rebinding produced distinguishable electrochemical responses, with an electrochemical imprinting ratio of approximately 6.5. These results demonstrate that GO can simultaneously regulate the structural stability and molecular recognition behavior of CaAlg-based imprinted hydrogels. The proposed hydrogel interface provides a promising material platform for selective protein recognition and electrochemical sensing, with potential applications in biomolecular detection and functional biointerfaces.</p>","PeriodicalId":12506,"journal":{"name":"Gels","volume":"12 10","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149265497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insights into the Protonation State and Counterion Interactions of Linear Polyethyleneimine Materials.","authors":"Agustín J Byrne, Daniel Vladimir, Yamila Garro-Linck, Guillermo J Copello, Ayelén F Crespi, Daniel Vega, Mariela Bollini, Paula G Franco, Juan M Lázaro-Martínez","doi":"10.3390/gels12100912","DOIUrl":"https://doi.org/10.3390/gels12100912","url":null,"abstract":"<p><p>Polyethyleneimine (PEI) polymers are widely used in the synthesis of nanoparticles, hydrogels and composite materials for biotechnological and environmental applications. However, the solid-state structural organization of linear PEI (L-PEI) materials, and how it is influenced by molecular weight, protonation state and counterion type, have not yet been comprehensively studied. In this work, <i>solid-state</i> nuclear magnetic resonance (<i>ss</i>-NMR), X-ray powder diffraction (XRD), small-angle X-ray scattering (SAXS) and time-domain NMR (TD-NMR) experiments were combined with theoretical calculations to analyze the local chemical environments, crystalline and nanoscale organization, and molecular mobility of L-PEI materials with different molecular weights. The analyzed materials were the free base (PEI·FB), the hydrochloride (PEI·HCl), the trifluoroacetate (PEI·TFA), and the sulfate-containing forms of L-PEI (PEI·Na₂SO₄ and PEI·H₂SO₄), as well as an intermediate protonation state obtained by the heterogeneous treatment with HCl-saturated isopropanol. Proton, ¹³C or ¹⁵N <i>ss</i>-NMR studies evidenced different chemical environments associated with changes in protonation state and counterion identity. Furthermore, XRD and SAXS showed that these variables, together with molecular weight and sample preparation conditions, influenced the crystalline arrangement and characteristic nanoscale organization of the polymer chains. Moreover, TD-NMR revealed the presence of three dynamically distinct proton populations, assigned to rigid, interfacial, and mobile domains, whose relative contributions and relaxation behavior varied among the PEI materials. Finally, high-resolution magic-angle spinning (HRMAS) NMR experiments were used to study different PEI-gel materials and films as well as the crosslinking of protonated PEI and sulfate ions.</p>","PeriodicalId":12506,"journal":{"name":"Gels","volume":"12 10","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149265555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Engineering Next-Generation Wound Gels for Advanced Healing.","authors":"Kannan Badri Narayanan","doi":"10.3390/gels12100908","DOIUrl":"https://doi.org/10.3390/gels12100908","url":null,"abstract":"<p><p>Wound healing is frequently perceived as a straightforward biological process; in practice, however, it remains a major challenge in clinical medicine due to the intricate, overlapping phases of hemostasis, inflammation, proliferation, and tissue remodeling [...].</p>","PeriodicalId":12506,"journal":{"name":"Gels","volume":"12 10","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149265538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and Characterization of <i>Phlomis brachyodon</i> Extract-Loaded Thermoresponsive In Situ Gels: Antioxidant Activity, Wound-Healing Evaluation in a Rat Excision Model, and Potential Anticancer Activity.","authors":"Nour Aboalhaija, Fatimah Al-Dulaimi, Osama H Abusara, Fatma Afifi, Heba Syaj, Baraa Hajjaj, Wasan Al-Farhan, Rania Hamed","doi":"10.3390/gels12100909","DOIUrl":"https://doi.org/10.3390/gels12100909","url":null,"abstract":"<p><p>This study aimed to characterize butanol and methanol extracts of <i>Phlomis brachyodon</i> (<i>P. brachyodon</i>) and incorporate them into thermoresponsive in situ gels (F1 and F2, respectively) to evaluate their wound-healing activity. Total phenolic content (TPC), total flavonoid content (TFC), and antioxidant activity of the extracts were determined. Extracts were profiled by LC-MS. The rheological properties of the gels, using a controlled-stress rheometer, and their wound-healing activity and histological examinations were evaluated. Cell viability assays of the extracts were conducted against human gingival fibroblasts (HGF) and a small-cell lung cancer cell line (H69). The methanol extract showed higher TPC and TFC values and stronger antioxidant activity than the butanol extract (IC₅₀, 55.82 ± 8.94 versus 144.11 ± 10.95 µg/mL). F1 and F2 underwent a sol-gel transition at temperatures suitable for topical application and exhibited shear-thinning behavior with predominantly elastic behavior. Both extract-loaded gels promoted wound contraction, with F2 producing the greatest reduction in wound area and near-complete closure by day 15. F1 and F2 gels showed complete re-epithelialization. LC-MS profiling detected 37 constituents and showed greater chemical diversity in the methanol extract. Both extracts had selectivity indices greater than 30 against H69 cancer cells, with IC₅₀ values of 3.16 and 2.24 µg/mL for the butanol and methanol extracts, respectively. <i>P. brachyodon</i> extract-loaded thermoresponsive gels, particularly the methanol extract formulation, showed promising antioxidant and wound-healing activity. In conclusion, these findings support the development of <i>P. brachyodon</i> topical formulations and demonstrate anticancer activity, particularly against H69 lung cancer cells, for <i>P. brachyodon</i> extracts.</p>","PeriodicalId":12506,"journal":{"name":"Gels","volume":"12 10","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149265398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Smartphone-Assisted Aerogel Colorimetric Sensor Array Coupled with Lightweight Deep Learning for Multi-Meat Freshness Monitoring.","authors":"Hanzhi Chen, Xiao Zhou, Caoyuan Zhang, Zengrui Wu, Bo Peng, Yingli Wang","doi":"10.3390/gels12100910","DOIUrl":"https://doi.org/10.3390/gels12100910","url":null,"abstract":"<p><p>Rapid assessment of chilled-meat freshness is constrained by conventional laboratory-based measurements. Although food-detection studies emphasize predictive performance, computational cost is reported less consistently. Here, we developed a 2 × 2 colorimetric sensor array based on a porous konjac glucomannan (KGM)/gelatin/starch/SiO₂ aerogel substrate loaded with four pH-sensitive dyes. Sensor images were acquired with a smartphone under standardized conditions, and four dye-responsive regions of interest (ROIs) were manually extracted and assembled into 2 × 2 dye-grid images. Five lightweight models-Spot-CNN, ShuffleNetV2-0.5x, EfficientNet-Lite0, MobileNetV3-Small and Tiny-MLP-were evaluated for classifying beef and pork freshness as Fresh, Sub-fresh or Spoiled. During chilled storage, the sensor color responses showed broadly consistent temporal trends with total volatile basic nitrogen (TVB-N). Under the fixed group-level split, Spot-CNN achieved image-unit-level accuracies of 0.933 and 0.938 and macro-AUC values of 0.995 and 0.982 on the beef and pork test sets, respectively. Tiny-MLP contained 0.013 M parameters and required less than 0.001 G floating-point operations, demonstrating lower computational cost. These results establish a controlled-laboratory prototype integrating an aerogel colorimetric sensor array, standardized smartphone image processing and lightweight-model comparison for multi-meat freshness screening. Further validation across meat batches, smartphone devices, lighting conditions and deployment environments is required.</p>","PeriodicalId":12506,"journal":{"name":"Gels","volume":"12 10","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149265531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and Evaluation of a Novel Zwitterionic Surfactant-Based Foaming Formulation for Gas Well Deliquification.","authors":"Sanbao Dong, Yao Yan, Haifeng Liu, Jiakui Chen, Jinhua Li, Weiwei Han, Chao Ma","doi":"10.3390/gels12100904","DOIUrl":"https://doi.org/10.3390/gels12100904","url":null,"abstract":"<p><p>A novel zwitterionic surfactant (HAPB) was synthesized and combined with lauramidopropyl trimethylammonium chloride (LATC) and alpha olefin sulfonate (AOS) to form a high-performance foaming formulation for gas well deliquification. The optimized LATC/AOS/HAPB formulation (15 mmol/L, molar ratio of 16/4/5) achieved a foaming volume and half-life of 400 mL and 9.46 min, respectively. Adding 0.2% sodium alginate (SA), a green polymer, the LATC/AOS/HAPB/SA foam's volume dropped to 350 mL; however, its half-life ramped to 55.47 min. With 0.1 SA and 0.01% calcium lactate (CL), the LATC/AOS/HAPB/SA/CL system exhibited excellent foaming and liquid-carrying performance. At 50% methanol, its liquid-carrying rate reached its maximum (57.44%), while the foaming rate remained 100%. Condensate oil slightly reduced the LATC/AOS/HAPB/SA/CL mixture's liquid-carrying performance, but did not affect its foaming ability, which was maintained at 100% below 50% condensate oil content. The foaming formulation demonstrated outstanding salt resistance, producing a liquid-carrying rate of 26.40% and a foaming rate of 90% at an extremely high salinity of 410 g/L, which was the highest level reported in the literature to date. Furthermore, surface tension tests and the foam's morphological analysis verified the presence of synergy among the LATC/AOS/HAPB/SA/CL system, which effectively enhanced its foaming capability, foam stability, and liquid-carrying ability.</p>","PeriodicalId":12506,"journal":{"name":"Gels","volume":"12 10","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149265445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multi-Stimuli-Responsive Hydrogels: From Strategic Design to Biomedical Applications.","authors":"Sijing Yi, Hao-Ying Li, Ru Chang","doi":"10.3390/gels12100906","DOIUrl":"https://doi.org/10.3390/gels12100906","url":null,"abstract":"<p><p>Multi-stimuli-responsive hydrogels have emerged as versatile biomaterial platforms for biomedical applications owing to their capacity to recognize and respond to multiple environmental signals. Such integration can provide responsiveness to signals that vary spatially and temporally. However, the effectiveness of such integrated systems requires more than simply incorporating signal-recognition components: the response characteristics of individual components must be preserved after integration and translated into measurable network-level changes rather than inferred from component-level sensitivity alone. This review develops a structure-response-application framework for multi-stimuli-responsive biomedical hydrogels. Strategies based on responsive polymer segments, dynamic covalent bonds, and functional nanocomposites are examined according to how responsive components are structurally integrated and coordinated to achieve application-specific functions. By connecting component integration with biomedical function, this cross-scale framework provides criteria for selecting integration strategies and assessing whether multiple responses are functionally coordinated rather than merely coincident.</p>","PeriodicalId":12506,"journal":{"name":"Gels","volume":"12 10","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149265476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surimi Gel Quality Enhanced by κ-Carrageenan/Konjac Glucomannan and Sodium Caseinate-Stabilized Emulsion.","authors":"Tianzhen Xiong, Lala Li, Guanchen Wu, Lihua Zhang, Wei Xu","doi":"10.3390/gels12100907","DOIUrl":"https://doi.org/10.3390/gels12100907","url":null,"abstract":"<p><p>This study investigated the effects of a combination of κ-carrageenan (CRG), konjac glucomannan (KGM) and a sodium caseinate-stabilized camellia oil emulsion on the quality attributes of surimi. The results demonstrated that adding the emulsion alone enhanced the textural properties but failed to increase the water-holding capacity (WHC) or reduce cooking loss. In contrast, incorporating both polysaccharides with the emulsion reduced cooking loss to 7.3% of that of the control (2.3 ± 1.0% vs. 31.4 ± 1.4%) and increased the WHC to 97.7 ± 1.3%, representing a 47.8% improvement over the control (66.1 ± 1.2%). Furthermore, this ternary composite system yielded substantial enhancements in the textural profile of the gels. These improvements were attributed primarily to the formation of hydrogen bonds between the polysaccharides and surimi proteins, which strengthened intermolecular interactions. Microstructural observations corroborated this mechanism, revealing that the composite system promoted the formation of a denser and more uniform network, which improved the freeze-thaw stability of the surimi. Sensory evaluation indicated that the combined treatment enhanced the flavor profile and acceptability of surimi gels. Thus, KGM and CRG can be combined with sodium caseinate-stabilized camellia oil emulsion to improve the quality of surimi gels. These results offer valuable theoretical guidance for advancing surimi-based foods.</p>","PeriodicalId":12506,"journal":{"name":"Gels","volume":"12 10","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149265547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Salt-Tolerant Non-Crosslinked Polymer Networks for High-Temperature Weighted Fracturing Fluids in Deep Hydrocarbon Reservoirs.","authors":"Jv Liu, Xin Qiao, Jianxin Peng, Lili Yan, Qingsong Cheng, Fei Peng, Bowen Zhong, Shulong Chen, Lingfeng Wu, Yang Bai","doi":"10.3390/gels12100905","DOIUrl":"https://doi.org/10.3390/gels12100905","url":null,"abstract":"<p><p>High-density potassium formate fracturing fluids require polymers that hydrate in concentrated brine while providing low friction and proppant suspension at high temperature. We hypothesized that the 2-acrylamido-2-methylpropanesulfonic acid (AMPS) content balances salt-tolerant hydration against molar-mass-dependent chain entanglement, enabling a reversible non-crosslinked network. Five hydrophobically associating copolymers based on acrylamide (AM) and AMPS, with AMPS feed contents of 5.5-23.8 wt%, were synthesized by low-temperature micellar copolymerization followed by post-hydrolysis. Polymer structure, molar mass, and solution conformation were determined by proton nuclear magnetic resonance spectroscopy and size-exclusion chromatography coupled with multi-angle light scattering. Hydration and thickening were evaluated in 1.40 g/cm³ potassium formate brine, followed by rheological testing at 160 °C, pipe-flow drag-reduction testing, and static proppant-suspension testing. Increasing the AMPS feed content decreased the weight-average molar mass from 25.83 × 10⁶ to 9.26 × 10⁶ g/mol, increased the chain-conformation exponent from 0.570 to 0.610, and shortened the time required to reach 90% hydration (t₉₀) from approximately 118 to 48 min. SN-4, containing 17.9 wt% AMPS, provided the best overall balance. A 0.60 wt% SN-4 fluid retained approximately 63 mPa·s after shearing at 160 °C and 170 s^-1 and recovered 92.1% of its viscosity after 300 s. Fresh and thermally sheared-recovered fluids maintained drag-reduction rates above 60%, and the recovered fluid reduced proppant settling velocity by 97.4%. These results support the proposed balance and demonstrate the potential of this reversible network for high-temperature weighted fracturing fluids in deep hydrocarbon reservoirs.</p>","PeriodicalId":12506,"journal":{"name":"Gels","volume":"12 10","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149265568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential and Safety Assessment of a Hydrogel as a Vitreous Substitute Following Vitrectomy in an Ex Vivo Porcine Model.","authors":"Soheil Sojdeh, Zahra Bibak Bejandi, Miranda Castillo, Gregory Tsougranis, Anwar N Khandaker, R V Paul Chan, Zohreh Arabpour, Ali R Djalilian","doi":"10.3390/gels12100900","DOIUrl":"https://doi.org/10.3390/gels12100900","url":null,"abstract":"<p><strong>Purpose: </strong>To develop and preliminarily evaluate a hyaluronic acid-1,4-butanediol diglycidyl ether (HA-BDDE)/polyethylene glycol-tyramine (PEG-Tyramine) dual-hydrogel designed as a transparent and injectable vitreous substitute with suitable optical, rheological, and cytocompatibility characteristics for potential application following vitrectomy.</p><p><strong>Methods: </strong>HA-BDDE and PEG-Tyramine were prepared separately and combined to form a dual-hydrogel formulation. The resulting hydrogel was characterized using attenuated total reflectance Fourier-transform infrared (ATR-FTIR) spectroscopy, proton nuclear magnetic resonance (¹H NMR) spectroscopy, oscillatory rheometry, and spectrophotometry to evaluate its chemical, rheological, and optical properties. Cytocompatibility was assessed using retinal pigment epithelial (RPE) cells through the methyl thiazolyl tetrazolium (MTT) assay and Live/Dead fluorescence staining. Ex vivo performance was evaluated following hydrogel injection into porcine eyes after vitrectomy, with assessment of macroscopic transparency, structural integrity, and retention within the vitreous cavity.</p><p><strong>Results: </strong>The HA-BDDE/PEG-Tyramine formulation formed a transparent and macroscopically homogeneous hydrogel phase. Spectroscopic analyses demonstrated the characteristic chemical functionalities and molecular environments associated with the HA- and PEG-containing components. Rheological analysis showed predominantly elastic, gel-like behavior, with the storage modules exceeding the loss modulus across the investigated frequency range. The hydrogel exhibited measurable and relatively stable visible-light transmission across the evaluated wavelength range. RPE cells maintained high metabolic activity during the culture period, while Live/Dead imaging demonstrated predominantly viable cells with limited dead-cell staining. In the ex vivo porcine model, the hydrogel remained within the vitreous cavity and maintained its macroscopic transparency and structural integrity during the observation period.</p><p><strong>Conclusions: </strong>The HA-BDDE/PEG-Tyramine dual-hydrogel exhibited favorable optical, rheological, cytocompatibility, and short-term ex vivo retention characteristics. These findings support further investigation of this dual-hydrogel system as a potential injectable vitreous substitute following vitrectomy.</p>","PeriodicalId":12506,"journal":{"name":"Gels","volume":"12 10","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149265550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}