Frontiers in Medicine最新文献

{"title":"Managing two cases of twin anemia-polycythemia sequence in monochorionic twin pregnancies.","authors":"Yongke Zhang, Yiheng Liang, Ran Chen, Dirong Zhang, Jing Wu","doi":"10.3389/fmed.2024.1504772","DOIUrl":"https://doi.org/10.3389/fmed.2024.1504772","url":null,"abstract":"<p><strong>Background: </strong>Twin anemia-polycythemia sequence (TAPS) is a rare monochorionic complication. In this study, we discuss the management of two cases of TAPS with different conditions.</p><p><strong>Case presentation: </strong>Patient 1 was a 34-year-old multigravida in whom the fetal middle cerebral artery peak systolic velocities (MCA-PSVs) were 0.86 multiples of the median (MoM) and 2.0 MoM at 33 weeks of gestation. After cesarean section, stage 3 TAPS was confirmed according to the ultrasound findings and hemoglobin results of the newborns and placenta examination after birth. Patient 2 was a nulligravida who was diagnosed with stage 2 TAPS at 18 weeks of gestation. The patient underwent fetoscopic laser surgery. Ultrasonography monitoring of the MCA-PSVs was performed on a schedule after surgery, with a good status but selective intrauterine growth restriction of one cotwin. The newborns reached their normal development milestones after spontaneous preterm birth.</p><p><strong>Conclusion: </strong>Optimal management should be carefully selected for patients with different TAPS conditions.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"11 ","pages":"1504772"},"PeriodicalIF":3.1,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11810567/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143398869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mapping knowledge landscapes and emerging trends in artificial intelligence for antimicrobial resistance: bibliometric and visualization analysis.","authors":"Zhongli Wang, Gaopei Zhu, Shixue Li","doi":"10.3389/fmed.2025.1492709","DOIUrl":"https://doi.org/10.3389/fmed.2025.1492709","url":null,"abstract":"<p><strong>Objective: </strong>To systematically map the knowledge landscape and development trends in artificial intelligence (AI) applications for antimicrobial resistance (AMR) research through bibliometric analysis, providing evidence-based insights to guide future research directions and inform strategic decision-making in this dynamic field.</p><p><strong>Methods: </strong>A comprehensive bibliometric analysis was performed using the Web of Science Core Collection database for publications from 2014 to 2024. The analysis integrated multiple bibliometric approaches: VOSviewer for visualization of collaboration networks and research clusters, CiteSpace for temporal evolution analysis, and quantitative analysis of publication metrics. Key bibliometric indicators including co-authorship patterns, keyword co-occurrence, and citation impact were analyzed to delineate research evolution and collaboration patterns in this domain.</p><p><strong>Results: </strong>A collection of 2,408 publications was analyzed, demonstrating significant annual growth with publications increasing from 4 in 2014 to 549 in 2023 (22.7% of total output). The United States (707), China (581), and India (233) were the leading contributors in international collaborations. The Chinese Academy of Sciences (53), Harvard Medical School (43), and University of California San Diego (26) were identified as top contributing institutions. Citation analysis highlighted two major breakthroughs: AlphaFold's protein structure prediction (6,811 citations) and deep learning approaches to antibiotic discovery (4,784 citations). Keyword analysis identified six enduring research clusters from 2014 to 2024: sepsis, artificial neural networks, antimicrobial resistance, antimicrobial peptides, drug repurposing, and molecular docking, demonstrating the sustained integration of AI in antimicrobial therapy development. Recent trends show increasing application of AI technologies in traditional approaches, particularly in MALDI-TOF MS for pathogen identification and graph neural networks for large-scale molecular screening.</p><p><strong>Conclusion: </strong>This bibliometric analysis shows the importance of artificial intelligence in enhancing the progress in the discovery of antimicrobial drugs especially toward the fight against AMR. From enhancing the fast, efficient and predictive performance of drug discovery methods, current AI capabilities have revealed observable potential to be proactive in combating the ever-growing challenge of AMR worldwide. This study serves not only an identification of current trends, but also, and especially, offers a strategic approach to further investigations.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1492709"},"PeriodicalIF":3.1,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11810743/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143398920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mouthguard types, properties and influence on performance in sport activities: a narrative review.","authors":"Ke Wang, Yitong Liu, Zihe Zhao, Shengjie Zhou, Min Zhang","doi":"10.3389/fmed.2025.1527621","DOIUrl":"https://doi.org/10.3389/fmed.2025.1527621","url":null,"abstract":"<p><p>Mouthguards are proven devices placed inside the mouth to prevent oral lacerations, dental injuries, and jaw fractures. Endorsed by the World Dental Federation, mouthguards are crucial for preventing orofacial and dental trauma. However, their adoption in sports is challenged by limited guidance, communication barriers, and cost considerations. Based on extensive literature research in PubMed/MEDLINE, this narrative review summarizes the historical development of mouthguards, elaborates on their primary classifications, and examines the factors influencing their properties. Importantly, the impact of mouthguards on sports performance is clarified in this study. Overall, using mouthguards in sports not only reduces the occurrence and severity of dental injuries but also holds promise for enhancing athletic performances such as strength, aerobic capacity, agility, balance, and flexibility. Therefore, promoting mouthguard use in the sports community should be encouraged.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1527621"},"PeriodicalIF":3.1,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11810891/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143398921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum: Refractory human cytomegalovirus infection without evidence of genetic resistance in the UL-54 and UL-97 genes in a pediatric hematopoietic stem cell transplant recipient: a case report.","authors":"Alejandra Pando-Caciano, Ketty Adid Escudero-Ramirez, Jackeline Carol Rodríguez-Torres, Holger Maita-Malpartida","doi":"10.3389/fmed.2025.1526535","DOIUrl":"https://doi.org/10.3389/fmed.2025.1526535","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.3389/fmed.2024.1335969.].</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1526535"},"PeriodicalIF":3.1,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11812928/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143398792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and clinical profile of comorbidity among newly diagnosed pulmonary tuberculosis patients: a multi-center observational study in eastern China.","authors":"Wei Wang, Xiaomeng Wang, Songhua Chen, Jun Li, Qinglin Cheng, Yu Zhang, Qian Wu, Kui Liu, Xuli Jiang, Bin Chen","doi":"10.3389/fmed.2025.1446835","DOIUrl":"https://doi.org/10.3389/fmed.2025.1446835","url":null,"abstract":"<p><strong>Objective: </strong>To identify the composition of comorbidities among patients with newly diagnosed pulmonary tuberculosis and assess the impact of comorbidities on the clinical characteristics of patients.</p><p><strong>Methods: </strong>This study was conducted in 13 hospitals across 13 counties in Zhejiang province, China. Patient data collected in this study included demographic characteristics, chest radiography results, etiological results, and comorbidities. Descriptive statistics were conducted to describe the composition of comorbidities of all participants. Univariate and multivariate logistic regression analyzes were performed to identify the effects of comorbidities on the clinical features of the participants.</p><p><strong>Results: </strong>Of the 8,421 total participants, 27.6% reported cavities in the chest radiography results, 41.9% were <i>Mycobacterium tuberculosis</i>-positive in the etiology test results, and 38.7% (3,258/8,421) had at least one type of comorbidity. The most predominant comorbidity was pleuritis (1,833, 21.8%), followed by diabetes mellitus (763, 9.1%), other extrapulmonary tuberculosis (421, 5%), tracheobronchial tuberculosis (275, 3.3%), and silicosis (160, 1.9%). Participants with diabetes mellitus had the highest rate of chest cavities on X-ray (54.8%), followed by those with silicosis (33.1%). In addition, a higher percentage of the <i>M. tuberculosis</i>-positive etiology (45%) was observed in participants without comorbidities than in participants with comorbidities (37.1%). Compared to patients without comorbidities, patients with diabetes mellitus (adjusted odds ratio [AOR]: 2.88, 95% confidence interval [CI]: 2.42-3.43) were more likely to show cavities in chest X-ray, while patients with pleuritis (AOR: 0.27, 95% CI: 0.23-0.32), other extrapulmonary tuberculosis (AOR: 0.48, 95% CI: 0.36-0.64), and tracheobronchial tuberculosis (AOR: 0.40-0.79) were less likely to show chest cavities in X-ray. In addition, patients with diabetes mellitus (AOR: 2.05, 95% CI: 1.72-2.45), tracheobronchial tuberculosis (AOR: 3.22, 95% CI: 2.4-4.32) were more likely to show <i>Mycobacterium tuberculosis</i>-positive in the etiology, and patients with pleuritis (AOR: 0.25, 95% CI: 0.22-0.29), other extrapulmonary tuberculosis (AOR: 0.61, 95% CI: 0.48-0.76) were less likely to show <i>Mycobacterium tuberculosis</i>-positive in the etiology.</p><p><strong>Conclusion: </strong>The prevalence of comorbidities was high in patients newly diagnosed with pulmonary tuberculosis. Thus, integration of screening and personalized management is needed for the control of tuberculosis and its comorbidities.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1446835"},"PeriodicalIF":3.1,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11810726/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143398001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Participation in a pre-registration student interprofessional education (IPE) society: influence on subsequent professional practice.","authors":"Christine Hirsch, Emily Audet, Ekrahh Dawood, Freya Beardmore, Nafeesa Hussain, Wing Chi Wong, Robert J Barry, Sharon Buckley","doi":"10.3389/fmed.2024.1497799","DOIUrl":"https://doi.org/10.3389/fmed.2024.1497799","url":null,"abstract":"<p><strong>Background: </strong>Student interprofessional education (IPE) societies or organizations are popular ways to support pre-registration health professions students to develop the understanding and skills needed for collaborative working. Our experience with the University of Birmingham Knowledge and Skills Exchange (KASE) is that, whilst such societies can be excellent vehicles for IPE, sustaining them can be challenging; and that consistent faculty support, adequate resource and a focus for society activities are needed for them to flourish. Whilst the longer term impact of pre-registration IPE has been demonstrated, less is known about the influence of student IPE society membership on participants' subsequent professional practice. To inform institutional decisions about establishing and maintaining a student IPE society, we have investigated the perceptions of early career health professionals who were KASE members during their pre-registration training.</p><p><strong>Methods: </strong>KASE alumni working as early career health professionals were invited to participate in the study. Their perceptions of the influence of KASE on their transition to practice and experience as early career health professionals were explored through online semi-structured interviews and interview transcripts analyzed thematically. Resulting themes were reviewed for relevance to the University of Birmingham (UK) IPE Framework, which uses the competency domains of the Canadian Interprofessional Health Collaborative Competency Framework as the required learning outcomes for IPE at Birmingham.</p><p><strong>Results: </strong>Eight interviews with former KASE members were conducted between November 2022 and March 2023. Interviewees had between 2 and 5 years of experience in their professional role. Six themes relating to the influence of KASE on their subsequent professional practice were identified: interprofessional communication, teamworking, patient-centered care, leadership and organizational skills, confidence and resilience. Three of these themes related to required IPE learning outcomes. Two further themes: time to build relationships; and informality and autonomy, suggested possible reasons for such influence.</p><p><strong>Conclusion: </strong>Early career health professionals considered that participation in the KASE student IPE society helped their transition into the healthcare work environment and encouraged them to adopt a more collaborative and patient-centered approach. Benefits reported suggest that faculty support for institutional student IPE societies is worthy of consideration.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"11 ","pages":"1497799"},"PeriodicalIF":3.1,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11811773/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143398791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: Physical exercise and metabolic health in children and adolescents.","authors":"Stevo Popovic, Gianpaolo De Filippo, Noelia Gonzalez-Galvez","doi":"10.3389/fmed.2025.1558522","DOIUrl":"https://doi.org/10.3389/fmed.2025.1558522","url":null,"abstract":"","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1558522"},"PeriodicalIF":3.1,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11810979/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143398795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of continuous positive airway pressure therapy on atrial fibrillation in patients with obstructive sleep apnea.","authors":"Jiancheng Hu, Siyuan Zuo, Jiahui Qian, Fangfang Cheng, Dengji Wang, Yanyan Deng, Dasheng Lu","doi":"10.3389/fmed.2025.1509776","DOIUrl":"https://doi.org/10.3389/fmed.2025.1509776","url":null,"abstract":"<p><p>Obstructive sleep apnea (OSA) stands as an autonomous risk factor for a broad spectrum of cardiovascular diseases, particularly atrial fibrillation (AF), which is closely associated with heightened morbidity and mortality rates. The intricate pathophysiological pathways linking OSA to AF encompass chronic intermittent hypoxia, disruptions in the autonomic nervous system, inflammatory responses, and alterations in ion channel function. Continuous positive airway pressure (CPAP) therapy emerges as the frontline treatment for moderate to severe OSA, effectively alleviating symptomatic manifestations and potentially mitigating cardiovascular risks. However, the influence of CPAP on AF among OSA patients remains a subject of debate. Some investigations underscore its beneficial effects, including the reversal of atrial remodeling, enhanced atrial conduction, decreased AF incidence, and improved outcomes post-AF ablation in CPAP-treated individuals. Conversely, other studies reveal neutral or insignificant impacts. This review delves into the repercussions of CPAP therapy on AF in OSA patients, exploring potential explanations for the discrepancies observed across existing research endeavors. By consolidating current evidence and pinpointing areas ripe for further inquiry, this review aspires to inform clinical decision-making regarding the management of OSA-related AF.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1509776"},"PeriodicalIF":3.1,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11810731/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143398251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global research trends on gastrointestinal cancer and mental health (2004-2024): a bibliographic study.","authors":"Wenjin Han, Tianmeng Wang, Zhiqiang He, Caihua Wang, Zhaozhao Hui, Shuangyan Lei, Nan Hao, Ning Li, Xiaoqin Wang","doi":"10.3389/fmed.2025.1515853","DOIUrl":"https://doi.org/10.3389/fmed.2025.1515853","url":null,"abstract":"<p><strong>Background: </strong>Gastrointestinal (GI) cancers impose a significant burden on global public health. Patients often experience mental health challenges due to physical changes and treatment-related symptoms, which can worsen their condition or delay recovery. Although research is mounting in this field, visual bibliometric analysis has not yet been conducted. This study aims to reveal the research hotspots and frontiers in this field using bibliometrics to guide future research.</p><p><strong>Methods: </strong>The publications on GI cancer and mental health were retrieved in the Web of Science Core Collection from 2004 to 2024. VOS Viewer and CiteSpace, as commonly used bibliometric analysis tools, were employed to visualize the network structure of bibliometric data and uncover the evolving trends in scientific research fields. VOS Viewer was used to identify keyword co-occurrences, while CiteSpace was utilized to generate network visualizations, produce dual-map overlays of journals, and perform burst keyword analysis.</p><p><strong>Results: </strong>A total of 1,118 publications were included for analysis. China had the highest number of publications in this field (341, 30.5%), while the United States held a central position (centrality = 0.48). The most productive author and institution were Floortje Mols and Tilburg University, respectively. Keyword analysis highlighted that \"quality of life\" (QoL) is a prominent research topic in the field, while \"complications,\" \"cancer-related fatigue,\" (CRF) \"chronic stress,\" and \"epidemiology\" have been identified as key areas for future research.</p><p><strong>Conclusion: </strong>Research interest in this field continues to grow. The research direction is mainly focused on personalized mental health interventions to improve QoL, as well as preoperative mental healthcare and ongoing care through internet-based multidisciplinary collaboration to reduce postoperative complications. More detailed clinical symptom assessment is needed to distinguish between CRF and mental health issues and to provide targeted intervention measures in the future. The mechanism of mental health effects on the occurrence and development of GI cancer will be a frontier.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1515853"},"PeriodicalIF":3.1,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11811116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143398919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on influencing factors of age-adjusted Charlson comorbidity index in patients with Alzheimer's disease based on machine learning model.","authors":"Jian Ding, Zheng Long, Yiming Liu, Min Wang","doi":"10.3389/fmed.2025.1497662","DOIUrl":"10.3389/fmed.2025.1497662","url":null,"abstract":"<p><strong>Background: </strong>Alzheimer's disease (AD) is a widespread neurodegenerative disease, often accompanied by multiple comorbidities, significantly increasing the risk of death for patients. The age adjusted Charlson Comorbidity Index (aCCI) is an important clinical tool for measuring the burden of comorbidities in patients, closely related to mortality and prognosis. This study aims to use the MIMIC-V database and various regression and machine learning models to screen and validate features closely related to aCCI, providing a theoretical basis for personalized management of AD patients.</p><p><strong>Methods: </strong>The research data is sourced from the MIMIC-V database, which contains detailed clinical information of AD patients. Multiple logistic regression, LASSO regression, random forest, Support Vector Machine (SVM), and Extreme Gradient Boosting (XGBoost) models were used to screen for feature factors significantly correlated with aCCI. By comparing model performance, evaluating the classification ability and prediction accuracy of each method, and ultimately selecting the best model to construct a regression model and a nomogram. The model performance is evaluated through classification accuracy, net benefit, and robustness. The feature selection results were validated by regression analysis.</p><p><strong>Results: </strong>Multiple models have performed well in classifying aCCI patients, among which the model constructed using LASSO regression screening feature factors has the best performance, with the highest classification accuracy and net benefit. LASSO regression identified the following 11 features closely related to aCCI: age, respiratory rate, base excess, glucose, red blood cell distribution width (RDW), alkaline phosphatase (ALP), whole blood potassium, hematocrit (HCT), phosphate, creatinine, and mean corpuscular hemoglobin (MCH). The column chart constructed based on these feature factors enables intuitive prediction of patients with high aCCI probability, providing a convenient clinical tool.</p><p><strong>Conclusion: </strong>The results of this study indicate that the features screened by LASSO regression have the best predictive performance and can significantly improve the predictive ability of aCCI related comorbidities in AD patients. The column chart constructed based on this feature factor provides theoretical guidance for personalized management and precise treatment of AD patients.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1497662"},"PeriodicalIF":3.1,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11807998/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143389890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}