Frontiers in Medicine最新文献

{"title":"Case Report: Hemolytic anemia secondary to infliximab treatment in a patient with ulcerative colitis.","authors":"Gerolamo Bevivino, Patrizio Scarozza, Michela Di Fonzo, Giulia Zerboni, Federico Iacopini","doi":"10.3389/fmed.2025.1548321","DOIUrl":"10.3389/fmed.2025.1548321","url":null,"abstract":"<p><p>Infliximab, a monoclonal antibody targeting tumor necrosis factor-alpha (TNF-α), is widely used in treating inflammatory bowel diseases (IBD), including ulcerative colitis (UC). While generally well-tolerated, infliximab is associated with rare but significant adverse effects, including autoimmune hemolytic anemia (AIHA). This report describes the case of a 54-year-old male diagnosed with UC, who developed hemolytic anemia secondary to infliximab therapy after 1 year of treatment. During the infusion preceding the onset of anemia, the patient experienced a severe infusion reaction characterized by urticaria, bronchospasm, chills, fever, and pulsating headache. Laboratory findings confirmed hemolytic anemia with a positive direct and negative indirect Coombs tests. The patient responded well to corticosteroid therapy (prednisone at 1 mg/kg/day for 30 days) and stopping anti-TNF-α, with hemoglobin levels improving from 7.2 g/dL at presentation to 14.6 g/dL after 1 month. AIHA should be considered an uncommon but serious complication of infliximab therapy, necessitating careful monitoring, especially in patients treated for gastrointestinal indications. This case underscores the importance of recognizing and managing infusion-related complications of biologic therapies.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1548321"},"PeriodicalIF":3.1,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11936980/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EEG-based epilepsy detection with graph correlation analysis.","authors":"Chongrui Tian, Fengbin Zhang","doi":"10.3389/fmed.2025.1549491","DOIUrl":"10.3389/fmed.2025.1549491","url":null,"abstract":"<p><p>Recognizing epilepsy through neurophysiological signals, such as the electroencephalogram (EEG), could provide a reliable method for epilepsy detection. Existing methods primarily extract effective features by capturing the time-frequency relationships of EEG signals but overlook the correlations between EEG signals. Intuitively, certain channel signals exhibit weaker correlations with other channels compared to the normal state. Based on this insight, we propose an EEG-based epilepsy detection method with graph correlation analysis (EEG-GCA), by detecting abnormal channels and segments based on the analysis of inter-channel correlations. Specifically, we employ a graph neural network (GNN) with weight sharing to capture target channel information and aggregate information from neighboring channels. Subsequently, Kullback-Leibler (KL) divergence regularization is used to align the distributions of target channel information and neighbor channel information. Finally, in the testing phase, anomalies in channels and segments are detected by measuring the correlation between the two views. The proposed method is the only one in the field that does not require access to seizure data during the training phase. It introduces a new state-of-the-art method in the field and outperforms all relevant supervised methods. Experimental results have shown that EEG-GCA can indeed accurately estimate epilepsy detection.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1549491"},"PeriodicalIF":3.1,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11937027/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The efficacy and safety of auricular acupoint therapy on treating functional dyspepsia with insomnia: study protocol for a randomized controlled trial.","authors":"Meng-Yuan Shen, Qin-Yi Lou, Shan Liu, Ze-Jiong Li, Tian-Chen Lin, Rong Zhou, Dan-Dan Feng, Dong-Dong Yang, Jian-Nong Wu","doi":"10.3389/fmed.2025.1496502","DOIUrl":"10.3389/fmed.2025.1496502","url":null,"abstract":"<p><strong>Background: </strong>Functional dyspepsia (FD) is a prevalent health issue currently lacking optimal treatment options, with its global incidence rate increasing in recent years. Clinical studies have recently focused on the application of auriculotherapy in functional gastrointestinal disorders that are accompanied by negative emotions. However, few randomized controlled trials have investigated the use of auriculotherapy for FD patients with insomnia, leaving the therapeutic efficacy and safety largely undefined. This study aims to evaluate the clinical efficacy and safety of auriculotherapy in treating FD patients with insomnia.</p><p><strong>Methods and analysis: </strong>This study is a single-center, randomized controlled clinical trial involving 80 patients with FD and insomnia. Using a central randomization system, the subjects are randomly assigned to the auricular acupressure group or the sham auricular acupressure group at a 1:1 ratio, with the auricular acupressure group targeting the concha region and the sham auricular acupressure group targeting the earlobe region. The primary outcome is the response rate at 2 weeks, and the secondary outcomes include the response rate at 8 weeks, sleep data assessed by actigraphy, modified Functional Dyspepsia Symptom Diary, short form-Nepean Dyspepsia Index, Self-rated Anxiety Scale, Self-rated Depression Scale, High Arousal Scale, and Heart Rate Variability. Efficacy results will be evaluated at baseline and at 2 and 8 weeks after treatment. Adverse events will be monitored throughout the study observation period.</p><p><strong>Discussion: </strong>The results of this trial are anticipated to validate the efficacy and safety of auriculotherapy in improving symptoms of FD and insomnia, as well as in reducing negative emotional states.</p><p><strong>Clinical trial registration: </strong>ClinicalTrials.gov, NCT06466044. Registered 14th May 2024, https://register.clinicaltrials.gov.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1496502"},"PeriodicalIF":3.1,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11937052/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case Report: Bilateral adrenal hemorrhage and hemophagocytosis in the reticuloendothelial system caused by <i>Escherichia coli</i> in a young woman: an autopsy case.","authors":"Yudai Tanaka, Koji Hayashi, Ei Kawahara, Shin-Ichiro Azuma, Maho Hayashi, Yuka Nakaya, Asuka Suzuki, Midori Ueda, Rei Asano, Hiromi Hayashi, Toyoaki Miura, Kouji Hayashi, Mamiko Sato, Yasutaka Kobayashi","doi":"10.3389/fmed.2025.1496961","DOIUrl":"10.3389/fmed.2025.1496961","url":null,"abstract":"<p><strong>Background: </strong>Sepsis can lead to life-threatening complications such as hemophagocytic lymphohistiocytosis (HLH) and bilateral adrenal hemorrhage (BAH), commonly known as Waterhouse-Friderichsen syndrome. HLH involves severe inflammation and organ damage, often linked with infections and autoimmune diseases, while BAH leads to adrenal insufficiency, typically caused by <i>Neisseria meningitidis</i>, though <i>Escherichia coli</i> (<i>E. coli</i>) is a rare cause.</p><p><strong>Case presentation: </strong>A 27-year-old Japanese woman, with a history of diabetes mellitus and obesity, presented with a complicated urinary tract infection. She commenced oral levofloxacin treatment five days before hospital admission. Her medications included prednisolone 5 mg/day, trimethoprim-sulfamethoxazole for pyoderma gangrenosum, and oral hypoglycemic agents. Upon admission, her vital signs, including body temperature and blood pressure, were stable, and her body mass index was recorded at 49.8. Laboratory tests indicated elevated white blood cell count and C-reactive protein. She was diagnosed with a urinary tract infection and was treated with levofloxacin and trimethoprim-sulfamethoxazole. On day 16 of hospitalization, her general condition rapidly worsened, leading to her sudden death on day 18. Premortem blood tests showed cytopenia, and blood cultures tested positive for <i>E. coli</i>. Autopsy imaging using computed tomography revealed enlargement and high density of the left adrenal gland. Postmortem pathology identified bilateral adrenal hemorrhages with focal necrosis. Extensive erythrophagocytic macrophages were observed in the bone marrow, spleen, and liver. Disseminated intravascular coagulopathy was confirmed through the detection of a renal glomerular fibrin thrombus.</p><p><strong>Conclusion: </strong>We concluded that <i>E. coli</i> infection had caused multiple fatal conditions, such as disseminated intravascular coagulopathy, bilateral adrenal hemorrhage, and suspected hemophagocytic lymphohistiocytosis leading to the death of the young woman.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1496961"},"PeriodicalIF":3.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11932846/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The current state and development trends of frailty research in diabetic patients: a bibliometric analysis.","authors":"Ziqi Xu, Rui Zhou, Xinran Zhou, Zhengyan Zhang, Qiong Li, Guodong Wang","doi":"10.3389/fmed.2025.1529218","DOIUrl":"10.3389/fmed.2025.1529218","url":null,"abstract":"<p><strong>Background: </strong>Diabetes mellitus is a global public health issue, often leading to organ damage, complications, and disabilities. Frailty is an age-related syndrome characterized by reduced physiological reserve and increased vulnerability to stressors, significantly affecting the prognosis of older diabetic patients. The prevalence of frailty is notably higher in older adults with diabetes than in those without. Therefore, a bibliometric analysis of research on diabetes-related frailty can provide deeper insights into the current state of this field and inform future research directions.</p><p><strong>Methods: </strong>This study retrieved English-language publications on diabetes-related frailty from the Web of Science Core Collection (WOS) database, covering the period from 2005 to 2023. A total of 403 articles were included in the analysis. Statistical analysis and data visualization were conducted using Microsoft Excel, R Studio, VOS viewer, and Cite Space 6.3.R1. The analysis emphasized journals, authors, keywords, country collaborations, institutional collaborations, and references to elucidate trends and knowledge structures within the field of diabetes-related frailty research.</p><p><strong>Results: </strong>The number of publications on diabetes-related frailty has been steadily increasing each year, with research predominantly focused in developed countries, particularly the United States and Europe. The University of London has emerged as the institution with the highest volume of publications, while Alan J. Sinclair has been recognized as a significant contributor to this field. Key research hotspots include the complications associated with diabetes-related frailty, epidemiology, and quality of life. Additionally, a timeline analysis of references suggests that diabetic nephropathy is currently at the forefront of research in this area.</p><p><strong>Conclusion: </strong>This comprehensive bibliometric analysis of diabetes-related frailty research underscores the necessity for improved international collaboration to further investigate the mechanisms underlying diabetes-related frailty and to devise more effective prevention and treatment strategies. Future research should emphasize the relationship between diabetic nephropathy and frailty, as well as the development of personalized intervention programs tailored for frail diabetic patients.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1529218"},"PeriodicalIF":3.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11933048/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe pneumonia caused by <i>Chlamydia abortus</i> complicated by hemophagocytic syndrome: a case report.","authors":"Jisong Xu, Haiwen Zeng, Huangen Li, Xiaoyun Lin, Tianlai Lin","doi":"10.3389/fmed.2025.1547766","DOIUrl":"10.3389/fmed.2025.1547766","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Pneumonia caused by &lt;i&gt;Chlamydia abortus&lt;/i&gt; (&lt;i&gt;C. abortus&lt;/i&gt;) is uncommon, particularly when complicated by severe acute respiratory distress syndrome (ARDS) and multiple organ dysfunction syndrome (MODS). Hemophagocytic lymphohistiocytosis (HLH) is a rare and potentially fatal disease characterized by the uncontrolled activation and non-malignant expansion of macrophages and T lymphocytes. This report describes a case of severe pneumonia complicated by hemophagocytic lymphohistiocytosis, caused by &lt;i&gt;Chlamydia abortus&lt;/i&gt;.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Case introduction: &lt;/strong&gt;A 42-year-old female with no history of underlying medical conditions, no known exposure to poultry or avian animals, and no consumption of undercooked sheep or ewes contaminated with infected placenta, presented to the respiratory medicine department with a 3-day history of fever, cough, and sputum production. Initially diagnosed with community-acquired pneumonia, she was treated with piperacillin-tazobactam for 5 days. However, despite 12 h of high-flow oxygen therapy, her oxygenation did not improve, and she was transferred to the ICU, where she received additional treatments, including moxifloxacin and methylprednisolone. Her condition worsened further, prompting the initiation of veno-venous extracorporeal membrane oxygenation (VV-ECMO) and bronchoalveolar lavage for metagenomic next-generation sequencing (mNGS) analysis. The mNGS results identified &lt;i&gt;Chlamydia abortus&lt;/i&gt; with a count of 180,791, leading to the cessation of moxifloxacin and the addition of omadacycline to her regimen. After 13 days of ECMO therapy, her condition improved, and the ECMO was discontinued. The endotracheal tube was successfully removed 15 days after intubation. However, 3 days later, the patient developed recurrent fever, pancytopenia, elevated ferritin, blood lipids, soluble CD25, and decreased natural killer cell activity, leading to a diagnosis of hemophagocytic lymphohistiocytosis (HLH). She was treated with ruxolitinib, etoposide, and other supportive medications. Despite treatment, her condition continued to deteriorate. Three days later, the family opted to discontinue therapy due to financial constraints. She passed away 12 h later.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;&lt;i&gt;Chlamydia abortus&lt;/i&gt; infection can result in severe acute respiratory distress syndrome (ARDS), necessitating prompt diagnosis and active clinical intervention. This case is unique due to the rare occurrence of HLH following &lt;i&gt;Chlamydia abortus&lt;/i&gt; infection, a pathogen not commonly associated with this condition. Metagenomic next-generation sequencing (mNGS) offers a distinct advantage in rapidly and accurately identifying rare pathogen infections, while extracorporeal membrane oxygenation (ECMO) can be an effective treatment for severe pneumonia caused by &lt;i&gt;Chlamydia abortus&lt;/i&gt;. It highlights the importance of early recognition and management of HLH in patients with severe, unexplained","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1547766"},"PeriodicalIF":3.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11933035/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nomenclature of renal involvement in diabetes mellitus: unify to manage diversity.","authors":"María Marques, José Portolés, Carmen Mora-Fernández, Alberto Ortiz, Juan F Navarro-González","doi":"10.3389/fmed.2025.1533011","DOIUrl":"10.3389/fmed.2025.1533011","url":null,"abstract":"<p><p>Diabetes mellitus is the most common cause of chronic kidney disease leading to kidney failure and premature death. Over the years, the nomenclature of kidney involvement in diabetes mellitus has evolved, driven both by the understanding that the phenotype may be more diverse than initially thought and by pragmatism. In clinical practice, most patients with diabetes mellitus do not undergo a comprehensive work-up (including kidney biopsy and genetic testing) to exclude the presence or coexistence of additional factors or other kidney diseases. Furthermore, the inclusion criteria for successful kidney protection clinical trials that are the basis of current guidelines covered a wide range of kidney phenotypes under the label of \"diabetes and kidney disease,\" without requiring proactive efforts to exclude other nephropathies. The aim of this review is to provide a critical review of the most common chronic kidney disease phenotypes in the context of diabetes mellitus and discuss the evolving nomenclature. Various topics are discuss diabetic kidney disease, classic diabetic nephropathy, regression of albuminuria, rapid progression, non-albuminuric and non-proteinuric kidney disease, the connections between and the impact of aging on these phenotypes and a glimpse into future phenotypes resulting from proactive prevention rather than reactive treatment of kidney disease in diabetes.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1533011"},"PeriodicalIF":3.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11933090/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Valuable insights into general practice staff's experiences and perspectives on AI-assisted diabetic retinopathy screening-An interview study.","authors":"Malene Krogh, Malene Hentze, Morten Sig Ager Jensen, Martin Bach Jensen, Marie Germund Nielsen, Henrik Vorum, Jette Kolding Kristensen","doi":"10.3389/fmed.2025.1565532","DOIUrl":"10.3389/fmed.2025.1565532","url":null,"abstract":"<p><strong>Aim: </strong>This study explores the hands-on experiences and perspectives of general practice staff regarding the feasibility of conducting artificial intelligence-assisted (AI-assisted) diabetic retinopathy screenings (DRS) in general practice settings.</p><p><strong>Method: </strong>The screenings were tested in 12 general practices in the North Denmark Region and were conducted as part of daily care routines over ~4 weeks. Subsequently, 21 staff members involved in the DRS were interviewed.</p><p><strong>Results: </strong>Thematic analysis generated four main themes: (1) Experiences with DRS in daily practice, (2) Effective DRS implementation in general practice in the future, (3) Trust and approval of AI-assisted DRS in general practice, and (4) Implications of DRS in general practice. The findings suggest that general practice staff recognise the potential for AI-assisted DRS to be integrated into their clinical workflows. However, they also emphasise the importance of addressing both practical and systemic factors to ensure successful implementation of DRS within the general practice setting.</p><p><strong>Conclusion: </strong>Focusing on the practical experiences and perspectives of general practice staff, this study lays the groundwork for future research aimed at optimising the implementation of AI-assisted DRS in general practice settings, while recognising that the insights gained may also inform broader primary care contexts.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1565532"},"PeriodicalIF":3.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11933039/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital recordings of a clinical encounter facilitate reflection in physical therapy students and clinicians.","authors":"Anthony Kinney, Amy Nordon-Craft, Suzan Kardong-Edgren, Anshul Kumar, Anne Thompson","doi":"10.3389/fmed.2024.1516724","DOIUrl":"10.3389/fmed.2024.1516724","url":null,"abstract":"<p><strong>Background: </strong>Medical and health professions students use digital media in their educational pursuits. No studies have examined the process or utility of reviewing digital recordings of a clinical encounter. This pilot study examined how physical therapy students varied in their approach when compared to practicing physical therapists, in their self-reflection and assessment of a recorded physical therapist (PT) encounter with a standardized patient (SP).</p><p><strong>Methods: </strong>A single site, cross-sectional, mixed-methods design was used. Participants reviewed an 11-minute digital recording of a patient encounter and completed survey questions. Post-survey interview sessions were used to gain additional perspective from participants.</p><p><strong>Results: </strong>Ninety-two physical therapy students across three levels of training and twenty-seven physical therapists participated in the study. Self-ratings of perceived clinical ability increased with each year of training. First-year students (PY1) gave higher performance ratings to the PT than other groups. Seventy-five percent of respondents found the review of the digital recording to be a useful tool for reflection. A variety of approaches in the review process were found across groups, especially between clinicians and students.</p><p><strong>Conclusion: </strong>Review of a recording of a physical therapist's encounter with an SP can be a useful educational tool for reflection across training levels of students and clinicians.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"11 ","pages":"1516724"},"PeriodicalIF":3.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11933041/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: From bench to bedside in gastric cancer: diagnosis, prognosis, and treatment, volume II.","authors":"Avtar Singh Meena, Alberto Bongiovanni","doi":"10.3389/fmed.2025.1562989","DOIUrl":"10.3389/fmed.2025.1562989","url":null,"abstract":"","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1562989"},"PeriodicalIF":3.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11933116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}