Frontiers in Medicine最新文献

{"title":"Building a rural medical workforce: the foundations of a place-based approach to program evaluation.","authors":"Lara Fuller, Jessica Beattie, Vincent L Versace, Gary D Rogers, Matthew Richard McGrail","doi":"10.3389/fmed.2025.1582793","DOIUrl":"10.3389/fmed.2025.1582793","url":null,"abstract":"<p><strong>Introduction: </strong>To address the maldistribution of medical practitioners within Deakin University's rural training footprint, a place-based Rural Training Stream (RTS) was established (2022). Formal definition of the footprint has enabled priority admission of 30 local students annually. This paper describes graduate workforce outcomes for the footprint, providing a baseline for future evaluation of the RTS.</p><p><strong>Methods: </strong>Graduates' (2011-2022) Principal Places of Practice (2023) were extracted from the Australian Health Practitioner Regulation Agency register and linked with demographic, admission and training data. Descriptive statistics, univariate analysis and multinomial logistic regression were employed to describe associations with practice in three defined rural Tiers (Tier 1: Deakin's rural footprint, Tier 2: other rural Victoria, Tier 3: other rural Australia), with metropolitan practice as the reference group.</p><p><strong>Results: </strong>120 (39.2%) graduates were working in Tier 1 and 93 (30.4%) in each of Tiers 2 and 3. Significant associations (<i>p</i> < 0.001) with working in the footprint were: post-graduate years 1-3 (OR 7.2), rural longitudinal integrated clerkship and rural clinical school (RCS) pathway (OR 6.8); RCS pathway only (OR 4.1), general practice specialty (OR 4.7) and rural background (OR 3.0).</p><p><strong>Discussion: </strong>The differential effect of rural training on graduates working in the rural footprint, compared with other parts of rural Victoria and Australia is noteworthy. Attrition of graduates from the footprint beyond post-graduate year three highlights the urgency of expanding rural specialty training pathways. These baseline data reinforce the place-based design of the RTS and provide a foundation for future evaluation of local workforce outcomes.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1582793"},"PeriodicalIF":3.1,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12241060/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144608046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: Hepatocellular carcinoma: from diagnostic approaches to surgical and systemic therapies.","authors":"Pradeep Kumar Shukla, Marcello Dallio, Liliana Chemello","doi":"10.3389/fmed.2025.1633587","DOIUrl":"https://doi.org/10.3389/fmed.2025.1633587","url":null,"abstract":"","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1633587"},"PeriodicalIF":3.1,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12242844/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144608012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation and comparison of large language models' responses to questions related optic neuritis.","authors":"Han-Jie He, Fang-Fang Zhao, Jia-Jian Liang, Yun Wang, Qian-Qian He, Hongjie Lin, Jingyun Cen, Feifei Chen, Tai-Ping Li, Zhanchi Hu, Jian-Feng Yang, Lan Chen, Carol Y Cheung, Yih-Chung Tham, Ling-Ping Cen","doi":"10.3389/fmed.2025.1516442","DOIUrl":"10.3389/fmed.2025.1516442","url":null,"abstract":"<p><strong>Objectives: </strong>Large language models (LLMs) show promise as clinical consultation tools and may assist optic neuritis patients, though research on their performance in this area is limited. Our study aims to assess and compare the performance of four commonly used LLM-Chatbots-Claude-2, ChatGPT-3.5, ChatGPT-4.0, and Google Bard-in addressing questions related to optic neuritis.</p><p><strong>Methods: </strong>We curated 24 optic neuritis-related questions and had three ophthalmologists rate the responses on two three-point scales for accuracy and comprehensiveness. We also assessed readability using four scales. The final results showed performance differences among the four LLM-Chatbots.</p><p><strong>Results: </strong>The average total accuracy scores (out of 9): ChatGPT-4.0 (7.62 ± 0.86), Google Bard (7.42 ± 1.20), ChatGPT-3.5 (7.21 ± 0.70), Claude-2 (6.44 ± 1.07). ChatGPT-4.0 (<i>p</i> = 0.0006) and Google Bard (<i>p</i> = 0.0015) were significantly more accurate than Claude-2. Also, 62.5% of ChatGPT-4.0's responses were rated \"Excellent,\" followed by 58.3% for Google Bard, both higher than Claude-2's 29.2% (all <i>p</i> ≤ 0.042) and ChatGPT-3.5's 41.7%. Both Claude-2 and Google Bard had 8.3% \"Deficient\" responses. The comprehensiveness scores were similar among the four LLMs (<i>p</i> = 0.1531). Note that all responses require at least a university-level reading proficiency.</p><p><strong>Conclusion: </strong>Large language models-Chatbots hold immense potential as clinical consultation tools for optic neuritis, but they require further refinement and proper evaluation strategies before deployment to ensure reliable and accurate performance.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1516442"},"PeriodicalIF":3.1,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12238082/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mapping and visualization of global research progress on autophagy in metabolic dysfunction-associated steatotic liver disease and metabolic syndrome: a bibliometric analysis (2009-2024).","authors":"Xing Liu, Xiang Li","doi":"10.3389/fmed.2025.1525526","DOIUrl":"10.3389/fmed.2025.1525526","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to delineate the current trends and hotspots in autophagy research related to metabolic syndrome (MetS) and metabolic dysfunction-associated steatotic liver disease (MASLD), with the aim of guiding future investigations in this area.</p><p><strong>Methods: </strong>This study extracted research on autophagy in MetS and MASLD from the Web of Science Core Collection (WoSCC) database. Review articles were systematically excluded to focus on original research contributions. A bibliometric analysis and visualization were conducted using VOSviewer 1.6.20, CiteSpace 6.3.R1, and R 4.3.3.</p><p><strong>Results: </strong>The study included 1,114 articles from 1,220 institutions across 42 countries/regions, demonstrating a significant increase in research output from 2009 to 2024. China led with 506 publications, followed by the USA and Korea. The Egyptian Knowledge Bank constitutes a consortium of institutions operating within the national research framework, with one institution designated as the primary publishing entity. Notably, the journal Nature has emerged as the most frequently cited publication. Singh Rajat received the highest number of citations (3,610), while Marycz Krzysztof was the most prolific author. The most cited article, published in 2009, was titled \"Autophagy regulates lipid metabolism.\" Keyword trends have shifted from earlier topics such as \"phosphorylation\" and \"gene-expression\" to more recent terms like \"lipid accumulation\" and \"mitophagy.\" Burst keyword analysis indicated that \"liver fibrosis,\" \"modulation,\" \"gut microbiota,\" and \"lipotoxicity\" have emerged as significant topics.</p><p><strong>Conclusions: </strong>This study has elucidated the protective role of autophagy in MASLD and MetS. Future research is anticipated to concentrate on the activation of autophagy in the context of natural product drug discovery, the exploration of underlying molecular mechanisms, the regulation of fatty acid metabolism, and the development of functional nutritional supplements, among other relevant areas.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1525526"},"PeriodicalIF":3.1,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12237938/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Motivation in medical students: higher intrinsic motivation among graduate-entry students across academic stages.","authors":"Rita Matos Sousa, Maurílio Santos, Marco Marangoni, Vitor Hugo Pereira","doi":"10.3389/fmed.2025.1625352","DOIUrl":"10.3389/fmed.2025.1625352","url":null,"abstract":"<p><p>Academic success and professional development are determined by several factors, being motivation an important one. In this study we explored its different dimensions of motivation among students enrolled in the undergraduate medical degree at the School of Medicine of the University of Minho, comparing students from the traditional national entry and graduate entry (PA) pathways across all curricular years. A total of 354 students (response rate: 39.4%) participated in this cross-sectional study during the 2023/2024 and 2024/2025 academic years. Motivation was assessed using the Minho Medical Academic Motivation Scale-Minho-MEDAMS, a validated scale adapted within the Self-Determination Theory framework. Motivation types examined included intrinsic motivation (IM), identified regulation (EMID), introjected regulation (EMIR), external regulation (EMER), and amotivation (AMOT), alongside the Self-Determination Index (SDI). Statistical analyses were conducted to compare motivation across academic years, entry pathways, gender, and age groups. EMID and IM were the most prevalent motivation types, while AMOT was the least reported. No significant differences were found in motivation levels across academic years. PA students showed significantly higher levels of IM, EMID, and SDI compared to traditional pathway students. Motivation levels did not vary significantly with age, and gender differences were minimal, with the exception of higher EMER scores among male students. In conclusion, these findings suggest that graduate-entry students are more self-determined in their motivation profiles, independent of age, and that motivation remains relatively stable throughout the medical curriculum.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1625352"},"PeriodicalIF":3.1,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12238096/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case Report: Heterotopic pregnancy after adenomyosis surgery: a rare case highlighting diagnostic pitfalls and clinical insights.","authors":"Qingqing Zhu, Shun Cao, Qi Wang, Jing Xu, Hongjie Hu","doi":"10.3389/fmed.2025.1606074","DOIUrl":"10.3389/fmed.2025.1606074","url":null,"abstract":"<p><p>We present an extremely rare heterotopic pregnancy (HP) in a 33-year-old patient with multiple adenomyosis surgeries and bilateral salpingectomy, who conceived via assisted reproductive technology (ART). According to a review of the literature spanning two decades, concurrent intrauterine and extrauterine pregnancies are uncommon, especially in the case of intramural ectopic gestations. On day 31 post-embryo transfer, only an intrauterine pregnancy (IUP) was observed by ultrasound. However, early vaginal bleeding and high-risk factors prompted further ultrasound, revealing an intramural ectopic pregnancy. Though MRI initially misdiagnosed the lesion, reevaluation led to the correct diagnosis. Surgical removal of the ectopic pregnancy was performed while preserving the IUP, which progressed uneventfully. In the late second trimester, follow-up MRI confirmed an intact posterior uterine myometrium, ruling out uterine rupture and resolving lingering concerns. This case illustrates a progression from incomplete ultrasound assessment to an initial misinterpretation of MRI. Ultimately, complementary imaging was vital for accurately diagnosing and managing the intramural ectopic pregnancy, while safeguarding the intrauterine pregnancy by confirming uterine wall integrity later on. Highlighting the complexity of HP in a patient with adenomyosis conceived via ART, it underscores the importance of multiple imaging techniques for early diagnosis and ongoing monitoring in high-risk scenarios. These findings guide clinical strategies and emphasize the critical role of accurate imaging in protecting both maternal and fetal wellbeing.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1606074"},"PeriodicalIF":3.1,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12237884/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic kidney disease as a catalyst for cerebral microbleeds: understanding the underlying mechanisms and treatment approaches.","authors":"Jia Yang, Xuezhi Chen, Xianming Cao, Hui Yang, Peiwen Liu, Xiaoping Yin, Xiaorong Zhang, Zhiying Chen","doi":"10.3389/fmed.2025.1578666","DOIUrl":"10.3389/fmed.2025.1578666","url":null,"abstract":"<p><p>Cerebral microbleeds (CMBs) are tiny deposits of blood degradation products in the brain that appear as small, low-signal lesions on magnetic resonance imaging paramagnetic susceptibility sequences. They are common forms of the cerebral small-vessel diseases and are thought to be associated with serious consequences such as cognitive decline and increased risk of stroke. Chronic kidney disease (CKD) is a chronic disease in which renal impairment lasts for more than 3 months and is often accompanied by pathophysiologic changes such as inflammation, abnormal vascular endothelial function, and increased oxidative stress. It has been found that chronic renal insufficiency can induce the onset, development, and aggravation of cognitive impairment of CMBs, which may be caused by hypertension, inflammation and immune response, vascular lesions, blood-brain barrier damage, vitamin D deficiency, and so on. Therefore, it is essential to study the mechanism of cerebral microbleeds induced by chronic kidney disease to prevent the occurrence, development, treatment, and prognosis of stroke and related events in patients in the future. This article summarizes the definition, epidemiological investigation, pathophysiological mechanism, correlation, and treatment status of CMBs and CKD.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1578666"},"PeriodicalIF":3.1,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12238016/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fetuin-B as a biomarker for metformin response in women with polycystic ovary syndrome: a prospective study.","authors":"Konstantin Hofmann, Susanne Singer, Ann-Christin Meyer, Susanne Theis, Annette Hasenburg, Walburgis Brenner, Christine Skala","doi":"10.3389/fmed.2025.1567255","DOIUrl":"10.3389/fmed.2025.1567255","url":null,"abstract":"<p><strong>Introduction: </strong>Polycystic ovary syndrome (PCOS), affecting 5-15% of women of reproductive age globally, is linked to metabolic complications such as insulin resistance, obesity, and non-alcoholic fatty liver disease. While metformin helps manage PCOS, reliable biomarkers for monitoring treatment response are lacking. Fetuin-B, a liver-derived protein, has emerged as a potential candidate, as previous studies have shown increased fetuin-B levels in women with PCOS. This study examined whether serum fetuin-B levels correlated with metabolic improvements in PCOS patients undergoing metformin therapy, exploring its potential as a biomarker.</p><p><strong>Methods: </strong>PCOS patients from the Fertility Center at the University Medical Center Mainz were assigned to two groups: metformin therapy (M-group) and alternative/no treatment (C-group), based on their metabolic profiles. Baseline and 24-week follow-up assessments included gonadotropins and reproductive hormone levels, metabolic markers (such as lipid profile, hepatic markers, fasting and stimulated glucose levels, and the respective derived indices), and anthropometric data, including fetuin-B. A multivariate regression analysis evaluated associations between metabolic changes and fetuin-B levels.</p><p><strong>Results: </strong>A total of 62 PCOS patients were included (31 per group). At baseline, the M-group exhibited worse metabolic parameters compared to the C-group, including higher body mass index (BMI) (<i>p</i> < 0.001), Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) (<i>p</i> < 0.001), waist circumference (<i>p</i> < 0.001), and fatty liver index (FLI) (<i>p</i> < 0.001). At follow-up, the M-group showed greater improvements. Fetuin-B levels were significantly higher in the M-group at baseline (<i>p</i> = 0.01), but at follow-up, no significant difference was observed between the groups (M-group: 3.7mcg/mL; C-group: 4.4 mcg/mL; <i>p</i> = 0.13). The M-group's fetuin-B levels decreased significantly (<i>p</i> < 0.001), while the C-group's levels increased slightly. Changes in fetuin-B levels differed significantly between groups (<i>p</i> < 0.001), and regression analysis confirmed a strong association (B: 1.80; 95% CIs: 0.57-3.03; <i>p</i> = 0.01).</p><p><strong>Conclusion: </strong>This study demonstrated that metformin therapy is associated with significantly reducing fetuin-B levels in PCOS patients, underscoring its role in enhancing metabolic health. These findings highlight fetuin-B as a potential biomarker for monitoring treatment efficacy, offering a link between metabolic and reproductive health.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1567255"},"PeriodicalIF":3.1,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12238098/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between family functioning and academic burnout among vocational college nursing students: mediating role of academic self-efficacy.","authors":"Yanying Yang, Sujiao Liu, Min Zhou, Lihong Miao, Xuejuan Liu","doi":"10.3389/fmed.2025.1590280","DOIUrl":"10.3389/fmed.2025.1590280","url":null,"abstract":"<p><strong>Introduction: </strong>Academic burnout is not uncommon and interferes with the role shift from nursing students to qualified nurses, aggravating a shortage of workforce in global healthcare system. However, there is currently a lack of research examining the relationship between family functioning, academic self-efficacy, and academic burnout in nursing students. The purpose of this study is to examine the relationship among family functioning, academic self-efficacy, and academic burnout among nursing students.</p><p><strong>Materials and methods: </strong>This cross-sectional survey recruited 2,847 nursing students from a three-year vocational school located in Henan province in eastern China and used an online questionnaire to measure the participants' basic information, family functioning, academic self-efficacy and academic burnout. Descriptive statistics, Pearson's correlation, multiple linear regression and mediation analyses were used.</p><p><strong>Results: </strong>The mean (SD) score of academic burnout among nursing students was 53.98 (10.87). Family functioning (<i>r</i> = -0.39, <i>p</i> < 0.001) and academic self-efficacy (<i>r</i> = -0.64, <i>p</i> < 0.001) were negatively correlated with academic burnout. Family functioning (<i>r</i> = 0.46, <i>p</i> < 0.001) was positively correlated with academic self-efficacy. At the same time, academic self-efficacy plays a partial mediating role (indirect effect = -1.009; 95% CI, -1.114 to -0.910) in the influence of family functioning on academic burnout.</p><p><strong>Conclusion: </strong>Nursing students with higher level of family functioning may have a stronger sense of academic self-efficacy, which could lead to a lower level of academic burnout. This finding provides important guidance for educational administrators to formulate targeted strategies to prevent academic burnout of nursing students.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1590280"},"PeriodicalIF":3.1,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12237952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Addressing treatment fatigue, therapeutic inertia, and cognitive dissonance in musculoskeletal pain management in primary care setting.","authors":"Waseem Jerjes, Daniel Harding, Aidan Hilton","doi":"10.3389/fmed.2025.1543434","DOIUrl":"10.3389/fmed.2025.1543434","url":null,"abstract":"","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1543434"},"PeriodicalIF":3.1,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12238004/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}